Abstract: A drug-loaded implanted medical device and a preparation method therefor. The drug-loaded implanted medical device comprises a device body and grooves (2) distributed on the surface of the device body, and at least one of the grooves (2) is loaded with a solid drug (11); the solid drug (11) is a crystal or has a form in which a crystal coexists with an amorphous body. The preparation method is implemented by loading the solid drug (11) into at least one of the grooves (2) by means of solution crystallization.

Abstract: The present invention discloses an application of clofoctol for manufacturing a pharmaceutical product for treating human neuroglioma. The clofoctol is a pharmaceutical product for treating an upper respiratory tract infection. The clofoctol exerts a significant and specific inhibition of a glioma stem cell activity relative to a human neuroglioma cell or a normal human astroglia, human embryonic kidney cell, and human neural stem cell. A glioma stem cell treated with the clofoctol exhibited significantly reduced self-renewal, tumorsphere formation, and in vivo tumor formation in a nude rat. In vivo experiments using a zebrafish glioma transplantation model and a nude rat glioma transplantation model provided in vivo verification for the therapeutic efficacy of the pharmaceutical product against glioma.

Abstract: A mask plate, an OLED display substrate, a display device and a manufacturing method thereof are provided. The mask plate includes: a mask plate body and a first blocking wall arranged on the mask plate body, where the mask plate body is provided with a plurality of openings, the plurality of openings are arranged in a matrix; the first blocking wall is arranged to close to the plurality of openings, and at least one part of the first blocking wall is arranged between two adjacent rows or adjacent columns of openings.

Abstract: Compositions and methods for treating or reducing the severity or likelihood of occurrence of a parasitic worm or helminth infection in a subject are described. The methods include administering to the subject a therapeutically effective amount of a recombinant bacterium expressing a crystal protein such as a Bacillus thuringiensis crystal protein (Cry). The crystal proteins may be full length, truncated, variant, or sub-variant Cry proteins. Examples of crystal proteins include Cry5B, Cry21, Cry14A, Cry6A, and Cry13A. The recombinant bacterium may be, for example, a Bacillus subtilis or other Gram-positive bacterium, for instance, a lactic acid fermenting bacterium such as Lactococcus or Lactobacillus. Related compositions and recombinant microorganisms are also described.

Abstract: A flexible substrate and a manufacture method thereof, and a flexible organic light-emitting diode display substrate. The flexible substrate comprises a first flexible layer and a second flexible layer stacked with each other and a hydrophobic layer on at least one side of at least one of the first flexible layer and the second flexible layer.

Abstract: The present disclosure provides a cesium tungsten bronze-based self-cleaning nano heat-insulation coating material, and method of preparing the same. Cesium tungsten bronze nanoparticles are prepared by hydrothermal method using WCl6 and CsOH.5H2O as raw materials, PVP as a surfactant and acetic acid as an acid catalyst. TiO2 nanoparticles are prepared from TiCl4. Subsequently ball milling and dispersing of the cesium tungsten bronze nanoparticles, the TiO2 nanoparticles, and a silane coupling agent with water to obtain an aqueous slurry containing cesium tungsten bronze/TiO2 composite particles is performed. The concentration of the aqueous slurry containing cesium tungsten bronze/TiO2 composite particles is adjusted to obtain a self-cleaning nano heat-insulation coating material.

Abstract: Aspects of the present invention disclose a method, computer program product, and system for content rendering. The method includes one or more processors retrieving at least one user interface (UI) component from a Document Object Model (DOM) tree. The method further includes one or more processors determining a corresponding rendering priority level (RPL) for each of the at least one UI component. The method further includes, in response to determining that the corresponding RPL of a first UI component of the at least one UI component is above a first threshold, one or more processors rendering the first UI component.

Abstract: A solid conductor including: a compound represented by Formula 1, a compound represented by Formula 2, or a combination thereof Li1+x+y?zTa2-xMxP1-yQyO8-zXz ??Formula 1 wherein, in Formula 1, M is an element having an oxidation number of +4, Q is an element having an oxidation number of +4, X is a halogen, a pseudohalogen, or a combination thereof, and 0?x?2, 0?y<1, and 0?z?2, except that cases i) x and y and z are simultaneously 0, ii) M is Hf, X is F, x is 1 , y is 0, and z is 1, iii) M is Hf, X is Cl, x is 2, y is 0, and z is 2, and iv) M is Hf, X is F, x is 2, y is 0, and z is 2, Li1+x+y?zTa2-xMxP1-yQyO8-zLiX ??Formula 2 wherein, in Formula 2, M is an element having an oxidation number of +4, Q is an element having an oxidation number of +4, X is a halogen, a pseudohalogen, or a combination thereof, and 0)(2, 0y<1, and 0z2, except that cases i) x and y and z are simultaneously 0, ii) M is Hf, X is F, x is 1 , y is 0, and z is 1, iii) M is Hf, X is Cl, x is 2, y is 0, and z is

Abstract: A compound of Formula 1: Li1+2x?yZn1?xPS4?y??Ay??(1) wherein A is halogen, 0?x?1, 0?y?0.5, and 0???0.5, and wherein the compound of Formula 1 has an body centered cubic crystal structure. Also a lithium battery and an electrode including the compound.

Abstract: The present invention relates to the field of treatment of diseases and immunology. Specifically, the present invention relates to an anti-LAG-3 antibody or an antigen-binding fragment thereof, nucleic acid molecules for encoding said antibody and fragment, and method for preparing said antibody and fragment. The anti-LAG-3 antibody or the antigen-binding fragment thereof according to the present invention has high specificity and high affinity to LAG-3, can effectively block the binding of LAG-3 to MHC II and/or FGL1, and can inhibit and/or block intracellular signaling mediated by LAG-3 binding to MHC II and/or FGL1. Therefore, the present invention further relates to a pharmaceutical composition comprising the antibody or the antigen-binding fragment thereof, and use of the pharmaceutical composition in the preparation of drugs.

Abstract: Aspects of the present invention disclose a method for identifying a relationship between objects of a NoSQL database based on queries of an application programming interface (API) call. The method includes one or more processors identifying an API call that includes two or more NoSQL query requests. The method further includes determining a class for the two or more NoSQL query requests of the API call. The method further includes determining whether a query value of the first NoSQL query request of the API call is present in a second NoSQL query request. The method further includes determining a relationship between the first NoSQL query request and the second NoSQL query request of the API call. The method further includes creating a view in a relational model database based on the respective determined classes for the two or more NoSQL query requests of the API call and the determined relationship.

Abstract: An evaporation mask plate, a manufacturing method thereof and an evaporation method are provided. The evaporation mask plate includes a body, a plurality of evaporation cutout regions formed in the body, and a plurality of shielding members arranged on the body. Each shielding member is arranged between two adjacent evaporation cutout regions.

Abstract: An improved mode of AFM imaging (Peak Force Tapping (PFT) Mode) uses force as the feedback variable to reduce tip-sample interaction forces while maintaining scan speeds achievable by all existing AFM operating modes. Sample imaging and mechanical property mapping are achieved with improved resolution and high sample throughput, with the mode workable across varying environments, including gaseous, fluidic and vacuum.

Abstract: A compound of Formula 1 Li1+(4?a)?Hf2??Ma?(PO4??)3??(1) wherein M is at least one cationic element with valence of a, wherein 0<???, 1?a?4, and 0???0.1. Also an electrolyte composition, a separator, a protected positive electrode, a protected negative electrode, and a lithium battery, each including the compound of Formula 1.

Abstract: Methods and apparatuses are provided for automatically controlling and stabilizing aspects of a scanning probe microscope (SPM), such as an atomic force microscope (AFM), using Peak Force Tapping (PFT) Mode. In an embodiment, a controller automatically controls periodic motion of a probe relative to a sample in response to a substantially instantaneous force determined and automatically controls a gain in a feedback loop. A gain control circuit automatically tunes a gain based on separation distances between a probe and a sample to facilitate stability. Accordingly, instability onset is quickly and accurately determined during scanning, thereby eliminating the need of expert user tuning of gains during operation.

Abstract: The disclosure discloses a method and apparatus for measuring a size of a crystal grain, and a method for fabricating a poly-silicon thin film. The method for measuring the size of the crystal grain includes: obtaining a grain morphology image of a crystalline region of a crystal, and drawing a grain interface diagram according to the grain morphology image; measuring at least one crystal grain in the grain interface diagram, and determining a transverse size and a longitudinal size of each measured crystal grain; and determining a transverse size and a longitudinal size of a crystal grain of the crystal according to the transverse size and the longitudinal size of each measured crystal grain.

Abstract: A flexible substrate and a manufacture method thereof, and a flexible organic light-emitting diode display substrate. The flexible substrate comprises a first flexible layer and a second flexible layer stacked with each other and a hydrophobic layer on at least one side of at least one of the first flexible layer and the second flexible layer.

Abstract: The present invention discloses an application of clofoctol for manufacturing a pharmaceutical product for treating human neuroglioma. The clofoctol is a pharmaceutical product for treating an upper respiratory tract infection. The clofoctol exerts a significant and specific inhibition of a glioma stem cell activity relative to a human neuroglioma cell or a normal human astroglia, human embryonic kidney cell, and human neural stem cell. A glioma stem cell treated with the clofoctol exhibited significantly reduced self-renewal, tumorsphere formation, and in vivo tumor formation in a nude rat. In vivo experiments using a zebrafish glioma transplantation model and a nude rat glioma transplantation model provided in vivo verification for the therapeutic efficacy of the pharmaceutical product against glioma.

Abstract: The present teachings relate to compositions for forming a negative-tone photopatternable dielectric material, where the compositions include, among other components, an organic filler and one or more photoactive compounds, and where the presence of the organic filler enables the effective removal of such photoactive compounds (after curing, and during or after the development step) which, if allowed to remain in the photopatterned dielectric material, would lead to deleterious effects on its dielectric properties.

Abstract: Provided herein are stable compositions containing anti-tau antibodies. In particular, compositions containing C2N-8E12 anti-tau antibody and a buffering system are provided herein.