Patents by Inventor Yan Poon
Yan Poon has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10857370Abstract: Implantable devices and/or sensors can be wirelessly powered by controlling and propagating electromagnetic waves in a patient's tissue. Such implantable devices/sensors can be implanted at target locations in a patient, to stimulate areas such as the heart, brain, spinal cord, or muscle tissue, and/or to sense biological, physiological, chemical attributes of the blood, tissue, and other patient parameters. The propagating electromagnetic waves can be generated with sub-wavelength structures configured to manipulate evanescent fields outside of tissue to generate the propagating waves inside the tissue. Methods of use are also described.Type: GrantFiled: February 12, 2019Date of Patent: December 8, 2020Assignee: The Board of Trustees of the Leland Stanford Junior UniversityInventors: Ada Shuk Yan Poon, Alexander Jueshyan Yeh, Yuji Tanabe, John Ho, Sanghoek Kim
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Patent number: 10843004Abstract: Implantable devices and/or sensors can be wirelessly powered by controlling and propagating electromagnetic waves in a patient's tissue. Such implantable devices/sensors can be implanted at target locations in a patient, to stimulate areas such as the heart, brain, spinal cord, or muscle tissue, and/or to sense biological physiological, chemical attributes of the blood, tissue, and other patient parameters. The propagating electromagnetic waves can be generated with sub-wavelength structures configured to manipulate evanescent fields outside of tissue to generate the propagating waves inside the tissue. Methods of use are also described.Type: GrantFiled: April 23, 2019Date of Patent: November 24, 2020Assignee: The Board of Trustees of the Leland Stanford Junior UniversityInventors: Ada Shuk Yan Poon, Alexander Jueshyan Yeh, Yuji Tanabe, John Ho, Sanghoek Kim
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Patent number: 10843003Abstract: Implantable devices and/or sensors can be wirelessly powered by controlling and propagating electromagnetic waves in a patient's tissue. Such implantable devices/sensors can be implanted at target locations in a patient, to stimulate areas such as the heart, brain, spinal cord, or muscle tissue, and/or to sense biological, physiological, chemical attributes of the blood, tissue, and other patient parameters. The propagating electromagnetic waves can be generated with sub-wavelength structures configured to manipulate evanescent fields outside of tissue to generate the propagating waves inside the tissue. Methods of use are also described.Type: GrantFiled: February 12, 2019Date of Patent: November 24, 2020Assignee: The Board of Trustees of the Leland Stanford Junior UniversityInventors: Ada Shuk Yan Poon, Alexander Jueshyan Yeh, Yuji Tanabe, John Ho, Sanghoek Kim
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Patent number: 10828502Abstract: Implantable devices and/or sensors can be wirelessly powered by controlling and propagating electromagnetic waves in a patient's tissue. Such implantable devices/sensors can be implanted at target locations in a patient, to stimulate areas such as the heart, brain, spinal cord, or muscle tissue, and/or to sense biological, physiological, chemical attributes of the blood, tissue, and other patient parameters. In some embodiments, the implantable devices can include power management schemes that have one or more AC-DC conversion chains arranged and configured to rectify the induced alternating current or voltage into one or more energy domains. Methods of use are also described.Type: GrantFiled: June 20, 2018Date of Patent: November 10, 2020Assignee: THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITYInventors: Ada Shuk Yan Poon, Alexander J. Yeh
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Publication number: 20200253991Abstract: This invention is based on the discovery that many eye conditions associated with aging are mediated at least in part by cells bearing a senescent phenotype. Senescent cells accumulate with age, and express factors that contribute to the pathophysiology of age related conditions. The data show that in age-matched patients, the severity of age-related conditions correlates with the abundance of senescent cells, and that clearing senescent cells can help abrogate the condition. Small molecule drugs that remove senescent cells from affected tissue in the eye are provided that have special efficacy in treating ophthalmic conditions. They not only inhibit progression of the disease, they can also reverse some of the pathophysiology—such as neovascularization and vaso-obliteration—that lead to vision loss. These senolytic agents have an appropriate dose and specificity profile to be effective in the clinical management of previously intractable ophthalmic conditions.Type: ApplicationFiled: February 14, 2020Publication date: August 13, 2020Inventors: Pam Tsuruda, Jill Hopkins, Harry Sweigard, Yan Poon, Jamie Dananberg, Daniel Marquess, Nathaniel David
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Publication number: 20200222000Abstract: An implantable device is provided that can include any number of features. In some embodiments, the device includes a coil antenna configured to receive wireless power from a power source external to the patient. The device can include at least one sensor configured to sense a bodily parameter of the patient. The device can also include electronics configured to communicate the sensed bodily parameter of to a device located external to the patient. Methods of use are also described.Type: ApplicationFiled: July 8, 2019Publication date: July 16, 2020Inventors: Ada Shuk Yan POON, Bob S. HU, Jihoon JANG, Anatoly YAKOVLEV, Yuji TANABE, Alex YEH, Stephanie HSU, Andrew MA
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Publication number: 20200204209Abstract: Described herein are methods of making and using and apparatus for wirelessly communicating data and providing power, particularly from a location exterior to a body and to an implantable device disposed within a body with tissue. The described embodiments provide apparatus and methods for efficiently transfer data and power between an external transceiver and an (implanted) biomedical device. The method is to modulate power carrier, which wirelessly powers the device, using an asynchronous modulation scheme, such as amplitude shift keying (ASK) modulation, with minimal modulation depth in order to not disrupt the power flow. The digital data is encoded in the pulse width, eliminating the need for synchronization to the power carrier signal and further minimizing the power consumption necessary for data transfer. Additionally, a reverse backscatter method for obtaining data from the implant is described that has flexible, low power operation.Type: ApplicationFiled: August 2, 2019Publication date: June 25, 2020Inventors: Anatoly Anatolievich Yakovlev, Daniel Pivonka, Ada Shuk Yan Poon, Teresa H. Meng
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Patent number: 10690735Abstract: In certain embodiments, a coil circuitry component may be configured to detect RF signals from excited spins of at least a region of an organism, where the coil circuitry component comprises a RF detection coil and a detuning circuit for detuning the RF detection coil. A coil signal detection component may be configured to extract at least some of the RF signals detected by the coil circuitry component and to convert the extracted RF signals from analog signal to digital signals. An excitation estimation component may be configured to estimate the excitation pulses from an excitation source and to generate a control timing signal from the estimated excitation pulses to set a state of the detuning circuit. A wireless communication component may be configured to wirelessly transmit the converted RF signals, the estimated excitation pulses, and the control timing signal to an external computer system.Type: GrantFiled: April 26, 2017Date of Patent: June 23, 2020Assignee: Aivitae LLCInventors: Bob Sueh-chien Hu, Ada Shuk-Yan Poon
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Patent number: 10644539Abstract: Described is a locomotive implant for usage within a predetermined magnetic field. In one embodiment magnetohydrodynamics is used to generate thrust with a plurality of electrodes. In another embodiment, asymmetric drag forces are used to generate thrust.Type: GrantFiled: July 22, 2016Date of Patent: May 5, 2020Assignee: THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITYInventors: Daniel Michael Pivonka, Anatoly Anatolievich Yakovlev, Ada Shuk Yan Poon, Teresa H. Meng
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Patent number: 10588916Abstract: This invention is based on the discovery that many eye conditions associated with aging are mediated at least in part by cells bearing a senescent phenotype. Senescent cells accumulate with age, and express factors that contribute to the pathophysiology of age related conditions. The data show that in age-matched patients, the severity of age-related conditions correlates with the abundance of senescent cells, and that clearing senescent cells can help abrogate the condition. Small molecule drugs that remove senescent cells from affected tissue in the eye are provided that have special efficacy in treating ophthalmic conditions. They not only inhibit progression of the disease, they can also reverse some of the pathophysiology—such as neovascularization and vaso-obliteration—that lead to vision loss. These senolytic agents have an appropriate dose and specificity profile to be effective in the clinical management of previously intractable ophthalmic conditions.Type: GrantFiled: October 15, 2018Date of Patent: March 17, 2020Assignee: Unity Biotechnology, Inc.Inventors: Pam Tsuruda, Jill Hopkins, Harry Sweigard, Yan Poon, Jamie Dananberg, Daniel Marquess, Nathaniel David
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Patent number: 10594166Abstract: A planar immersion lens can include any number of features. A planar immersion lens can be configured to control a phase profile of an incident wave by modulating the incident wave with sub-wavelength structures of varying impedances. The planar immersion lens can also be directly excited, with electronics or other subwavelength sources coupled to the planar immersion lens, to generate a wave with the desired phase profile. The planar immersion lens can include a plurality of metallic elements and passive elements disposed over a substrate. The passive elements can be selected, based on both the intrinsic and mutual impedances of the elements, to shape the spatial phase profile of the incident wave within this phase range. The phase gradient can be introduced along the incident material/refractive material interface to focus the incident wave into the refractive material having wave components at or beyond the critical angle. Methods are also provided.Type: GrantFiled: September 28, 2015Date of Patent: March 17, 2020Assignee: THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITYInventors: John S. Y. Ho, Ada Shuk Yan Poon
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Patent number: 10434329Abstract: A power transmitter is provided that can include a microwave cavity resonant at a desired operating frequency, a hexagonal mesh top to leak evanescent fields out of the cavity, and a plurality of orthogonal monopole feeds with 90 degrees phase differences creating circularly polarized waves. The power transmitter can be configured to transmit energy to a wireless device implanted in an animal passing through the evanescent fields. Implantable devices are also described which can receive wireless energy from the power transmitter and stimulate the animals (e.g., optogenetic or electrical stimulation).Type: GrantFiled: March 25, 2015Date of Patent: October 8, 2019Assignee: THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITYInventors: Ada Shuk Yan Poon, John S. Y. Ho, Yuji Tanabe, Alexander J. Yeh, Kate L. Montgomery, Logan Grosenick, Emily A. Ferenczi, Vivien Tsao, Shrivats Mohan Iyer, Scott Lee Delp, Karl Deisseroth
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Patent number: 10411760Abstract: Described herein are methods of making and using and apparatus for wirelessly communicating data and providing power, particularly from a location exterior to a body and to an implantable device disposed within a body with tissue. The described embodiments provide apparatus and methods for efficiently transfer data and power between an external transceiver and an (implanted) biomedical device. The method is to modulate power carrier, which wirelessly powers the device, using an asynchronous modulation scheme, such as amplitude shift keying (ASK) modulation, with minimal modulation depth in order to not disrupt the power flow. The digital data is encoded in the pulse width, eliminating the need for synchronization to the power carrier signal and further minimizing the power consumption necessary for data transfer. Additionally, a reverse backscatter method for obtaining data from the implant is described that has flexible, low power operation.Type: GrantFiled: September 29, 2017Date of Patent: September 10, 2019Assignee: THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITYInventors: Anatoly Anatolievich Yakovlev, Daniel Michael Pivonka, Ada Shuk Yan Poon, Teresa H. Meng
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Publication number: 20190247667Abstract: Implantable devices and/or sensors can be wirelessly powered by controlling and propapting electromagnetic waves in a patient's tissue. Such implantable devices/sensors can be implanted at target locations in a patient, to stimulate areas such as the heart, brain, spinal cord, or muscle tissue, and/or to sense biological physiological, chemical attributes of the blood, tissue, and other patient parameters. The propagating electromagnetic waves can be generated with sub-wavelength structures configured to manipulate evanescent fields outside of tissue to generate the propagating waves inside the tissue. Methods of use are also described.Type: ApplicationFiled: April 23, 2019Publication date: August 15, 2019Inventors: Ada Shuk Yan Poon, Alexander Jueshyan Yeh, Yuji Tanabe, John Ho, Sanghoek Kim
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Patent number: 10322289Abstract: Implantable devices and/or sensors can be wirelessly powered by controlling and propagating electromagnetic waves in a patient's tissue. Such implantable devices/sensors can be implanted at target locations in a patient, to stimulate areas such as the heart, brain, spinal cord, or muscle tissue, and/or to sense biological, physiological, chemical attributes of the blood, tissue, and other patient parameters. The propagating electromagnetic waves can be generated with sub-wavelength structures configured to manipulate evanescent fields outside of tissue to generate the propagating waves inside the tissue. Methods of use are also described.Type: GrantFiled: November 17, 2017Date of Patent: June 18, 2019Assignee: The Board of Trustees of the Leland Stanford Junior UniversityInventors: Ada Shuk Yan Poon, Alexander Yeh, Yuji Tanabe, John Ho, Sanghoek Kim
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Publication number: 20190175920Abstract: Implantable devices and/or sensors can be wirelessly powered by controlling and propagating electromagnetic waves in a patient's tissue. Such implantable devices/sensors can be implanted at target locations in a patient, to stimulate areas such as the heart, brain, spinal cord, or muscle tissue, and/or to sense biological, physiological, chemical attributes of the blood, tissue, and other patient parameters. The propagating electromagnetic waves can be generated with sub-wavelength structures configured to manipulate evanescent fields outside of tissue to generate the propagating waves inside the tissue. Methods of use are also described.Type: ApplicationFiled: February 12, 2019Publication date: June 13, 2019Inventors: Ada Shuk Yan Poon, Alexander Jueshyan Yeh, Yuji Tanabe, John Ho, Sanghoek Kim
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Publication number: 20190175922Abstract: Implantable devices and/or sensors can be wirelessly powered by controlling and propagating electromagnetic waves in a patient's tissue. Such implantable devices/sensors can be implanted at target locations in a patient, to stimulate areas such as the heart, brain, spinal cord, or muscle tissue, and/or to sense biological, physiological, chemical attributes of the blood, tissue, and other patient parameters. The propagating electromagnetic waves can be generated with sub-wavelength structures configured to manipulate evanescent fields outside of tissue to generate the propagating waves inside the tissue. Methods of use are also described.Type: ApplicationFiled: February 12, 2019Publication date: June 13, 2019Inventors: Ada Shuk Yan Poon, Alexander Jueshyan Yeh, Yuji Tanabe, John Ho, Sanghoek Kim
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Publication number: 20190175919Abstract: Implantable devices and/or sensors can be wirelessly powered by controlling and propagating electromagnetic waves in a patient's tissue. Such implantable devices/sensors can be implanted at target locations in a patient, to stimulate areas such as the heart, brain, spinal cord, or muscle tissue, and/or to sense biological, physiological, chemical attributes of the blood, tissue, and other patient parameters. The propagating electromagnetic waves can be generated with sub-wavelength structures configured to manipulate evanescent fields outside of tissue to generate the propagating waves inside the tissue. Methods of use are also described.Type: ApplicationFiled: February 12, 2019Publication date: June 13, 2019Inventors: Ada Shuk Yan Poon, Alexander Jueshyan Yeh, Yuji Tanabe, John Ho, Sanghoek Kim
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Publication number: 20190175923Abstract: Implantable devices and/or sensors can be wirelessly powered by controlling and propagating electromagnetic waves in a patient's tissue. Such implantable devices/sensors can be implanted at target locations in a patient, to stimulate areas such as the heart, brain, spinal cord, or muscle tissue, and/or to sense biological, physiological, chemical attributes of the blood, tissue, and other patient parameters. The propagating electromagnetic waves can be generated with sub-wavelength structures configured to manipulate evanescent fields outside of tissue to generate the propagating waves inside the tissue. Methods of use are also described.Type: ApplicationFiled: February 12, 2019Publication date: June 13, 2019Inventors: Ada Shuk Yan Poon, Alexander Jueshyan Yeh, Yuji Tanabe, John Ho, Sanghoek Kim
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Publication number: 20190175921Abstract: Implantable devices and/or sensors can be wirelessly powered by controlling and propagating electromagnetic waves in a patient's tissue. Such implantable devices/sensors can be implanted at target locations in a patient, to stimulate areas such as the heart, brain, spinal cord, or muscle tissue, and/or to sense biological, physiological, chemical attributes of the blood, tissue, and other patient parameters. The propagating electromagnetic waves can be generated with sub-wavelength structures configured to manipulate evanescent fields outside of tissue to generate the propagating waves inside the tissue. Methods of use are also described.Type: ApplicationFiled: February 12, 2019Publication date: June 13, 2019Inventors: Ada Shuk Yan Poon, Alexander Jueshyan Yeh, Yuji Tanabe, John Ho, Sanghoek Kim