Abstract: The present invention relates to a Rho-associated protein kinase inhibitor of formula (I), a pharmaceutical composition comprising the same, a preparation method thereof, and a use of the same in preventing or treating a disease mediated by Rho-associated protein kinase (ROCK).

Abstract: A P2X3 and/or P2X2/3 receptor antagonist of formula (I), a pharmaceutical composition comprising the same, and a use thereof in preparing a drag for preventing or treating a disease mediated by the P2X3 and/or P2X2/3 receptor antagonist.

Abstract: The present invention relates to the field of biomedicine, particularly to double-stranded RNA molecules targeting CKIP-1 and uses thereof, particularly to use of the double-stranded RNA molecules for the treatment of inflammatory diseases such as arthritis, particularly rheumatoid arthritis.

Abstract: There is provided an oil pumping apparatus including: (1) a connector connected to a device; (2) a top platform; (3) a roller disposed on a top platform; (4) a motor disposed on the top platform; (5) a driven belt to enable synchronous drives to operate the roller; (6) a load belt moveable over the roller, one end of the load belt being connected to the connector, and the other end of the load belt being connected to a balance box to balance the weight of the device; and (7) a control system for the apparatus. When the motor rotates in a clockwise direction, the motor drives the roller rotate in the clockwise direction and the device moves down vertically; and when the motor rotates in an anticlockwise direction, the motor drives the roller rotate in the anticlockwise direction and the device moves up vertically.

Abstract: The present invention relates to a Rho-associated protein kinase inhibitor of formula (I), a pharmaceutical composition comprising the same, a preparation method thereof, and a use of the same in preventing or treating a disease mediated by Rho-associated protein kinase (ROCK).

Abstract: A vertical pumping unit for pumping oil from a well is disclosed including a vertically oriented frame, an electrically powered motor, a flexible beam connected on a first end to pumping machinery lowered into an oil well hole, a counterweight connected to a second end of the flexible beam and suspended by the frame, and a drum-type deceleration roller cone. The roller cone includes an input shaft receiving torque from the motor, internal reduction machinery, and an output drum translating the flexible beam back and forth to activate a pumping action.

Abstract: There is provided an oil pumping apparatus including: (1) a connector connected to a device; (2) a top platform; (3) a roller disposed on a top platform; (4) a motor disposed on the top platform; (5) a driven belt to enable synchronous drives to operate the roller; (6) a load belt moveable over the roller, one end of the load belt being connected to the connector, and the other end of the load belt being connected to a balance box to balance the weight of the device; and (7) a control system for the apparatus. When the motor rotates in a clockwise direction, the motor drives the roller rotate in the clockwise direction and the device moves down vertically; and when the motor rotates in an anticlockwise direction, the motor drives the roller rotate in the anticlockwise direction and the device moves up vertically.

Abstract: The present invention relates to a Rho-associated protein kinase inhibitor of Formula (I), a pharmaceutical composition comprising the same, a preparation method thereof, and use thereof for the prevention or treatment of a disease mediated by the Rho-associated protein kinase (ROCK).

Abstract: The present invention relates to a Rho-associated protein kinase inhibitor of Formula (I), a pharmaceutical composition comprising the same, a preparation method thereof, and use thereof for the prevention or treatment of a disease mediated by the Rho-associated protein kinase (ROCK).

Abstract: The present invention relates to a Rho-associated protein kinase inhibitor of Formula (I), a pharmaceutical composition comprising the same, a preparation method thereof, and use thereof for the prevention or treatment of a disease mediated by the Rho-associated protein kinase (ROCK).

Abstract: The present invention relates to a Rho-associated protein kinase inhibitor of Formula (I), a pharmaceutical composition comprising the same, a preparation method thereof, and use thereof for the prevention or treatment of a disease mediated by the Rho-associated protein kinase (ROCK).

Abstract: There is provided an oil pumping apparatus including: a connector; a first roller mounted on a first frame and being rotatable about a first axle, a load belt moveable over the first roller, having one end connected to the connector and having another end connected with a hanging frame; a second roller being mounted with the hanging frame and being rotatable about a second axle; a third roller being mounted on the first frame and being rotatable about a third axle; a driven belt being moveable over the second roller, the driven belt being fixed at one end, and having another end being connected with the third roller; a control system for the apparatus; and a motor.

Abstract: There is provided an oil pumping apparatus including: a connector; a first roller mounted on a first frame and being rotatable about a first axle, a load belt moveable over the first roller, having one end connected to the connector and having another end connected with a hanging frame; a second roller being mounted with the hanging frame and being rotatable about a second axle; a third roller being mounted on the first frame and being rotatable about a third axle; a driven belt being moveable over the second roller, the driven belt being fixed at one end, and having another end being connected with the third roller; a control system for the apparatus; and a motor.

Abstract: A clapping type electromagnetic tripping system comprises an iron core with a U-shaped structure, an armature, a heating element, a bimetallic element and a connecting plate; a bracket extends into a U-shaped groove of the iron core and is fixedly connected with the iron core, and a wire connecting the heating element and the connecting plate surrounds the iron core and the bracket; the bracket twined round by the wire is fixedly connected with the middle part of the heating element, the bottom end of the heating element and the bottom end of the bimetallic element are fixedly connected with a supporting member together, and the armature is hung on the bracket surrounded by the wire; and the armature and the iron core twined round by the wire are arranged oppositely to form a magnetic loop, and one end of the armature is attracted by the iron core so as to swing when short-circuit current is generated.

Abstract: A clapping type electromagnetic tripping system comprises an iron core with a U-shaped structure, an armature, a heating element, a bimetallic element and a connecting plate; a bracket extends into a U-shaped groove of the iron core and is fixedly connected with the iron core, and a wire connecting the heating element and the connecting plate surrounds the iron core and the bracket; the bracket twined round by the wire is fixedly connected with the middle part of the heating element, the bottom end of the heating element and the bottom end of the bimetallic element are fixedly connected with a supporting member together, and the armature is hung on the bracket surrounded by the wire; and the armature and the iron core twined round by the wire are arranged oppositely to form a magnetic loop, and one end of the armature is attracted by the iron core so as to swing when short-circuit current is generated.

Abstract: A vertical pumping unit for pumping oil from a well is disclosed including a vertically oriented frame, an electrically powered motor, a flexible beam connected on a first end to pumping machinery lowered into an oil well hole, a counterweight connected to a second end of the flexible beam and suspended by the frame, and a drum-type deceleration roller cone. The roller cone includes an input shaft receiving torque from the motor, internal reduction machinery, and an output drum translating the flexible beam back and forth to activate a pumping action.

Abstract: Polypeptides having an amino acid sequence of SEQ ID NO: 2, and having amino acid residues 9 to 27 of SEQ ID NO: 2 are disclosed, which are together named C-terminal polypeptides of CKLF1. Also disclosed is a pharmaceutical composition containing a therapeutically effective amount of the CKLF1 C-terminal polypeptide and pharmaceutically acceptable salts, carrier or excipient. Further disclosed are the polynucleotides encoding the C-terminal polypeptides of CKLF1, and vectors and host cells containing the polynucleotides; the in vitro assays for detecting the expression level of the polypeptide or polynucleotide in a test sample; and the monoclonal or polyclonal antibodies against the polypeptides or active fragments thereof. The polypeptides of the present invention can be pharmaceutically used for treating the HIV infection, allergic disease, allograft rejection, diseases in brain and autoimmune diseases.

Abstract: Polypeptides having an amino acid sequence of SEQ ID NO: 2, and having amino acid residues 9 to 27 of SEQ ID NO: 2 are disclosed, which are together named C-terminal polypeptides of CKLF1. Also disclosed is a pharmaceutical composition containing a therapeutically effective amount of the CKLF1 C-terminal polypeptide and pharmaceutically acceptable salts, carrier or excipient. Further disclosed are the polynucleotides encoding the C-terminal polypeptides of CKLF1, and vectors and host cells containing the polynucleotides; the in vitro assays for detecting the expression level of the polypeptide or polynucleotide in a test sample; and the monoclonal or polyclonal antibodies against the polypeptides or active fragments thereof. The polypeptides of the present invention can be pharmaceutically used for treating the HIV infection, allergic disease, allograft rejection, diseases in brain and autoimmune diseases.