Patents by Inventor Yao-En Li
Yao-En Li has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20140256980Abstract: A continuous process and system for manufacturing beta-hydroxy-beta-methylbutyrate (HMB) and salts thereof is provided. The continuous process includes providing at least one oxidant and diacetone alcohol, and combining the at least one oxidant with the diacetone alcohol in a first flow reactor to produce a product stream comprising HMB or a salt thereof. Optionally, the process includes a second flow reactor for the acidification of a salt of beta-hydroxy-beta-methylbutyrate to produce beta-hydroxy-beta-methylbutyrate in free acid form.Type: ApplicationFiled: August 15, 2012Publication date: September 11, 2014Applicant: ABBOTT LABORATORIESInventor: Yao-En Li
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Publication number: 20080287675Abstract: A method of purifying an active pharmaceutical ingredient sufficient for administration into a human subject can include: obtaining a reaction product composition having the active pharmaceutical ingredient and impurities, wherein said active pharmaceutical ingredient is rapamycin or a rapamycin analog; introducing the reaction product composition into a first column of a chromatography system; directing a first portion of a first elutant from the first column to waste, said first portion having more impurity than active pharmaceutical ingredient; directing a second portion of the first elutant from the first column into a second column, said second portion having more active pharmaceutical ingredient than impurity; collecting factions of a second elutant from the second column that include the active pharmaceutical ingredient; and concentrating the said collected fractions to obtain a purity of the active pharmaceutical ingredient greater than 98% and with less than or about 0.Type: ApplicationFiled: May 15, 2008Publication date: November 20, 2008Applicant: ABBOTT LABORATORIESInventor: Yao-En Li
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Patent number: 6605133Abstract: Processes and systems to recover at least one perfluorocompound gas from a gas mixture are provided. In one embodiment the inventive process comprises the steps of a) providing a gas mixture comprising at least one perfluorocompound gas and at least one carrier gas, the gas mixture being at a predetermined pressure; b) providing at least one glassy polymer membrane having a feed side and a permeate side; c) contacting the feed side of the at least one membrane with the gas mixture; d) withdrawing from the feed side of the membrane as a non-permeate stream at a pressure which is substantially equal to the predetermined pressure a concentrated gas mixture comprising essentially the at least one perfluorocompound gas; and e) withdrawing from the permeate side of the membrane as a permeate stream a depleted gas mixture comprising essentially the at least one carrier gas.Type: GrantFiled: April 23, 1999Date of Patent: August 12, 2003Assignees: L'Air Liquide - Societe Anonyme a' Directoire et Conseil de Surveillance pour l'Etude et l'Exploitation des Procedes Georges Claude, American Air LiquideInventors: Yao-En Li, Joseph E. Paganessi, David Vassallo, Gregory K. Fleming
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Patent number: 6517771Abstract: A system useful for superadiabatic combustion generation of a reducing atmosphere for metal heat treatment includes a superadiabatic reactor which supplies a reducing atmosphere to a metal heat treatment apparatus.Type: GrantFiled: November 13, 2000Date of Patent: February 11, 2003Assignee: L'Air Liquide - Societe Anonyme a Directoire et Conseil de Surveillance pour l'Etude et l'Exploitation des Procedes Georges ClaudeInventor: Yao-En Li
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Publication number: 20030019551Abstract: A system useful for superadiabatic combustion generation of a reducing atmosphere for metal heat treatment includes a superadiabatic reactor which supplies a reducing atmosphere to a metal heat treatment apparatus.Type: ApplicationFiled: September 25, 2002Publication date: January 30, 2003Inventor: Yao-En Li
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Patent number: 6458217Abstract: Systems useful for superadiabatic combustion generation of a reducing atmosphere for metal heat treatment include a superadiabatic reactor which supplies a reducing atmosphere to a metal heat treatment apparatus. In one aspect, the reactor includes a porous medium and a start-up heater in the flow path of the gas that is to be heated. In another aspect, the gas is passed through a porous medium in alternating, opposite directions by the control of valves which lead the gas to and from the medium. In yet another aspect, a gas inflow pipe leads into an insulated porous bed from which the gas flows in a counter flow manner around the inflow pipe.Type: GrantFiled: February 29, 2000Date of Patent: October 1, 2002Assignee: American Air Liquide, Inc.Inventor: Yao-En Li
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Patent number: 6444011Abstract: Processes and systems to recover at least one perfluorocompound gas from a gas mixture are provided. In one embodiment the inventive process comprises the steps of a) providing a gas mixture comprising at least one perfluorocompound gas and at least one carrier gas, the gas mixture being at a predetermined pressure; b) providing at least once glassy polymer membrane having a feed side and a permeate side; c) contacting the feed side of the at least one membrane with the gas mixture; d) withdrawing from the feed side of the membrane as a non-permeate stream at a pressure which is substantially equal to the predetermined pressure a concentrated gas mixture comprising essentially the at least one perfluorocompound gas; and e) withdrawing from the permeate side of the membrane as a permeate stream a depleted gas mixture comprising essentially the at least one carrier gas.Type: GrantFiled: January 25, 2001Date of Patent: September 3, 2002Assignee: American Air Liqide, Inc.Inventors: Yao-En Li, Jospeh E. Paganessi, David Vassallo, Gregory K. Fleming
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Patent number: 6389845Abstract: A method and apparatus for the separation and recovery of SF6 from a gas mixture consisting essentially of SF6, CF4, and N2. The method and apparatus involve membrane separation to separate N2 from SF6 and CF4, and liquefaction to separate SF6 from CF4.Type: GrantFiled: March 8, 2000Date of Patent: May 21, 2002Assignee: American Air Liquide, Inc.Inventor: Yao-En Li
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Patent number: 6312502Abstract: Processes and systems to recover at least one perfluorocompound gas from a gas mixture are provided. In one embodiment the inventive process comprises the steps of a) providing a gas mixture comprising at least one perfluorocompound gas and at least one carrier gas, the gas mixture being at a predetermined pressure; b) providing at least one glassy polymer membrane having a feed side and a permeate side; c) contacting the feed side of the at least one membrane with the gas mixture; d) withdrawing from the feed side of the membrane as a non-permeate stream at a pressure which is substantially equal to the predetermined pressure a concentrated gas mixture comprising essentially the at least one perfluorocompound gas; and e) withdrawing from the permeate side of the membrane as a permeate stream a depleted gas mixture comprising essentially the at least one carrier gas.Type: GrantFiled: April 23, 1999Date of Patent: November 6, 2001Assignees: L'Air Liquide, Societe Anonyme pour l'Etude et l'Exploitation des Procedes Georges Claude, American Air LiquideInventors: Yao-En Li, Jospeh E. Paganessi, David Vassallo, Gregory K. Fleming
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Publication number: 20010029841Abstract: Processes and systems to recover at least one perfluorocompound gas from a gas mixture are provided. In one embodiment the inventive process comprises the steps of a) providing a gas mixture comprising at least one perfluorocompound gas and at least one carrier gas, the gas mixture being at a predetermined pressure; b) providing at least once glassy polymer membrane having a feed side and a permeate side; c) contacting the feed side of the at least one membrane with the gas mixture; d) withdrawing from the feed side of the membrane as a non-permeate stream at a pressure which is substantially equal to the predetermined pressure a concentrated gas mixture comprising essentially the at least one perfluorocompound gas; and e) withdrawing from the permeate side of the membrane as a permeate stream a depleted gas mixture comprising essentially the at least one carrier gas.Type: ApplicationFiled: January 25, 2001Publication date: October 18, 2001Inventors: Yao-En Li, Joseph E. Paganessi, David Vassallo, Gregory K. Fleming
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Patent number: 6254666Abstract: Processes and systems to recover at least one perfluorocompound gas from a gas mixture are provided. In one embodiment the inventive process comprises the steps of a) providing a gas mixture comprising at least one perfluorocompound gas and at least one carrier gas, the gas mixture being at a predetermined pressure; b) providing at least one glassy polymer membrane having a feed side and a permeate side; c) contacting the feed side of the at least one membrane with the gas mixture; d) withdrawing from the feed side of the membrane as a non-permeate stream at a pressure which is substantially equal to the predetermined pressure a concentrated gas mixture comprising essentially the at least one perfluorocompound gas; and e) withdrawing from the permeate side of the membrane as a permeate stream a depleted gas mixture comprising essentially the at least one carrier gas.Type: GrantFiled: March 28, 2000Date of Patent: July 3, 2001Assignees: L'Air Liquide, Societe Anonyme pour l'Etude et l'Exploitation des Procedes Georges Claude, American Air LiquideInventors: Yao-En Li, Jospeh E. Paganessi, David Vassallo, Gregory K. Fleming
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Patent number: 6214089Abstract: Processes and systems to recover at least one perfluorocompound gas from a gas mixture are provided. In one embodiment the inventive process comprises the steps of a) providing a gas mixture comprising at least one perfluorocompound gas and at least one carrier gas, the gas mixture being at a predetermined pressure; b) providing at least one glassy polymer membrane having a feed side and a permeate side; c) contacting the feed side of the at least one membrane with the gas mixture; d) withdrawing from the feed side of the membrane as a non-permeate stream at a pressure which is substantially equal to the predetermined pressure a concentrated gas mixture comprising essentially the at least one perfluorocompound gas; and e) withdrawing from the permeate side of the membrane as a permeate stream a depleted gas mixture comprising essentially the at least one carrier gas.Type: GrantFiled: July 21, 1998Date of Patent: April 10, 2001Assignees: American Air Liquide, Inc., L'Air Liquide, Societe Anonyme pour l'Etude et, l'Exploitation des Procedes Georges ClaudeInventors: Yao-En Li, Jospeh E. Paganessi, David Vassallo, Gregory K. Fleming
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Patent number: 6187077Abstract: A process for separating at least one of CF4 and C2F6 from a gas. The process includes the steps of: (a) contacting a gas mixture comprising (i) at least one of CF4 and C2F6, (ii) at least one of NF3, CHF3, and N2, and (iii) SF6 with a membrane at conditions effective to obtain a retentate stream rich in SF6 and at least one of CF4 and C2F6, and a permeate stream rich in at least one of NF3, CHF3, and N2; and (b) contacting the retentate stream with an adsorbent at conditions effective to adsorb SF6 and produce a product stream rich in at least one of CF4 and C2F6.Type: GrantFiled: April 17, 1998Date of Patent: February 13, 2001Assignee: American Air Liquide Inc.Inventor: Yao-En Li
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Patent number: 6096114Abstract: A process for recovering SF.sub.6 from a gas is provided. The process includes the step of contacting a gas stream comprising SF.sub.6 and at least one of N.sub.2, O.sub.2, CO.sub.2, and H.sub.2 O with a membrane in at least one membrane separation unit at conditions effective to obtain a retentate stream rich in SF.sub.6 and a permeate stream rich in at least one of N.sub.2, O.sub.2, CO.sub.2, and H.sub.2 O. A process for forming solidified Mg metal is also provided. The process includes recovering and/or recycling of SF.sub.6 and/or CO.sub.2.Type: GrantFiled: October 30, 1998Date of Patent: August 1, 2000Assignees: American Air Liquide, Inc., Air Liquide Canada, Inc.Inventors: Yao-En Li, Magdy Meimari
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Patent number: 5968334Abstract: A process for recovering at least one of CF.sub.4 and C.sub.2 F.sub.6 from a vent gas from an aluminum electrolysis cell. The process includes the steps of:(a) removing inorganic fluorides from a vent gas comprising inorganic fluorides and at least one of CF.sub.4 and C.sub.2 F.sub.6 to obtain a purified vent gas; and(b) contacting the purified vent gas with a membrane at conditions effective to obtain a retentate stream rich in at least one of CF.sub.4 and C.sub.2 F.sub.6, and a permeate stream depleted in at least one of CF.sub.4 and C.sub.2 F.sub.6.Type: GrantFiled: May 1, 1998Date of Patent: October 19, 1999Assignee: American Air Liquide Inc.Inventor: Yao-En Li
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Patent number: 5919285Abstract: Processes and systems to recover at least one perfluorocompound gas from a gas mixture are provided. In one embodiment the inventive process comprises the steps of a) providing a gas mixture comprising at least one perfluorocompound gas and at least one carrier gas, the gas mixture being at a predetermined pressure; b) providing at least one glassy polymer membrane having a feed side and a permeate side; c) contacting the feed side of the at least one membrane with the gas mixture; d) withdrawing from the feed side of the membrane as a non-permeate stream at a pressure which is substantially equal to the predetermined pressure a concentrated gas mixture comprising essentially the at least one perfluorocompound gas; and e) withdrawing from the permeate side of the membrane as a permeate stream a depleted gas mixture comprising essentially the at least one carrier gas.Type: GrantFiled: April 3, 1998Date of Patent: July 6, 1999Assignees: American Air Liquide, Inc., l'Air Liquide, Societe Anonyme Pour l'Etude et, l'Exploitation Des Procedes Georges ClaudeInventors: Yao-En Li, Joseph E. Paganessi, David Vassallo, Gregory K. Fleming
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Patent number: 5858065Abstract: Processes and systems to recover at least one perfluorocompound gas from a gas mixture are provided. In one embodiment the inventive process comprises providing a gas mixture comprising at least one perfluorocompound gas and at least one carrier gas, the gas mixture being at a predetermined pressure; providing at least one size selective membrane having a feed side and a permeate side; contacting the feed side of the at least one membrane with the gas mixture; withdrawing from the feed side of the membrane as a non-permeate stream at a pressure which is substantially equal to the predetermined pressure a concentrated gas mixture comprising essentially the at least one perfluorocompound gas; and withdrawing from the permeate side of the membrane as a permeate stream a depleted gas mixture comprising essentially the at least one carrier gas.Type: GrantFiled: January 16, 1997Date of Patent: January 12, 1999Assignee: American Air LiquideInventors: Yao-En Li, Joseph E. Paganessi, David Vassallo, Gregory K. Fleming
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Patent number: 5855647Abstract: A process for recovering SF.sub.6 from a gas is provided. The process includes the step of contacting a gas stream comprising SF.sub.6 and at least one of N.sub.2, O.sub.2, CO.sub.2, and H.sub.2 O with a membrane in at least one membrane separation unit at conditions effective to obtain a retentate stream rich in SF.sub.6 and a permeate stream rich in at least one of N.sub.2, O.sub.2, CO.sub.2, and H.sub.2 O.Type: GrantFiled: May 15, 1997Date of Patent: January 5, 1999Assignee: American Air Liquide, Inc.Inventors: Yao-En Li, Magdy Meimari
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Patent number: 5814127Abstract: A process for recovering at least one of CF.sub.4 and C.sub.2 F.sub.6 from a vent gas from an aluminum electrolysis cell. The process includes the steps of:(a) removing inorganic fluorides from a vent gas comprising inorganic fluorides and at least one of CF.sub.4 and C.sub.2 F.sub.6 to obtain a purified vent gas; and(b) contacting the purified vent gas with a membrane at conditions effective to obtain a retentate stream rich in at least one of CF.sub.4 and C.sub.2 F.sub.6, and a permeate stream depleted in at least one of CF.sub.4 and C.sub.2 F.sub.6.Type: GrantFiled: December 23, 1996Date of Patent: September 29, 1998Assignee: American Air Liquide Inc.Inventor: Yao-En Li
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Patent number: 5785741Abstract: Processes and systems to recover at least one perfluorocompound gas from a gas mixture are provided. In one embodiment the inventive process comprises the steps of a) providing a gas mixture comprising at least one perfluorocompound gas and at least one carrier gas, the gas mixture being at a predetermined pressure; b) providing at least one glassy polymer membrane having a feed side and a permeate side; c) contacting the feed side of the at least one membrane with the gas mixture; d) withdrawing from the feed side of the membrane as a non-permeate stream at a pressure which is substantially equal to the predetermined pressure a concentrated gas mixture comprising essentially the at least one perfluorocompound gas; and e) withdrawing from the permeate side of the membrane as a permeate stream a depleted gas mixture comprising essentially the at least one carrier gas.Type: GrantFiled: June 14, 1996Date of Patent: July 28, 1998Assignees: L'Air Liquide, Societe Anonyme pour l'Etude et l'Exploitation des Procedes Georges, Claude, American Air LiquideInventors: Yao-En Li, Joseph E. Paganessi, David Vassallo, Gregory K. Fleming