Abstract: An antibody specifically binding to PD-1 and a functional fragment thereof. The antibody or functional fragment thereof includes a PD-1 chimeric antibody and a functional fragment thereof, and a PD-1 humanized antibody and a functional fragment thereof.

Abstract: The present invention provides a method for production of stable and highly specific heterodimeric immunoglobulin constructs, e.g., bispecific antibodies, retaining desirable properties of native IgG and lacking undesirable heavy chain-light chain mispairing, that can simultaneously bind two target molecules and are more potent in the treatment of complex diseases.

Abstract: An antibody specifically binding to IL-17A or a functional fragment thereof. The antibody or functional fragment thereof includes an IL-17A chimeric antibody and a functional fragment thereof, and an IL-17A humanized antibody and a functional fragment thereof.

Abstract: The present invention provides a bifunctional fusion protein comprising the extracellular region of CTLA4 and an anti-IL-17 antibody, a gene encoding the protein, a vector comprising the gene, a host cell comprising the vector, and a pharmaceutical composition containing the protein.

Abstract: A guard assembly for an abrasive accessory of a power tool is provided, including a guard shell being associated with a first surface of the abrasive accessory and secured to the power tool around an output spindle of the power tool; and a guard cover being associated with a second surface of the abrasive accessory opposite the first surface and attached to the guard shell at a pivot point having an axis that is at a distance from an axis of the spindle, the guard cover being rotatably movable with respect to the guard shell around the pivot point.

Abstract: A guard assembly for an abrasive accessory of a power tool is provided, including an inner guard secured to the power tool around an output spindle of the power tool, and an outer guard secured to the inner guard at a pivot point along or in close proximity to an axis of the spindle. The outer guard is rotatably movable with respect to the inner guar around the pivot point between a retracted position, where the inner and outer guards together cover a first angular area of the abrasive accessory, and an extended position, where the inner and outer guards together cover a second angular area of the abrasive accessory larger than the first angular area.

Abstract: It's disclosed a current monitor and an electric power quality compensation system. The current monitor includes: an internal monitor module configured to output a measurement of current for characterizing a real-time electric power quality of an external power network based on a received detection current, wherein an external detection module is used to detect a current of the external power network and output a first level detection current; and an isolation and transfer module including an input side and an output side electrically isolated from each other, wherein the input side is configured to be connected with the external detection module, and the output side is configured to be connected with the internal monitor module, the isolation and transfer module receives the first level detection current and outputs a second level detection current to the internal monitor module.

Abstract: A multiple inverter and an active power filter system are disclosed in the invention, said multiple inverter can decrease the volume and harmonics, increase the efficiency and decrease the cost, and can be applied to various occasions. The technical scheme is: the filter assembly in the multiple inverter is installed at the output inductor of the multiple inverter for filtering the harmonics.

Abstract: It's disclosed a current monitor and an electric power quality compensation system. The current monitor includes: an internal monitor module configured to output a measurement of current for characterizing a real-time electric power quality of an external power network based on a received detection current, wherein an external detection module is used to detect a current of the external power network and output a first level detection current; and an isolation and transfer module including an input side and an output side electrically isolated from each other, wherein the input side is configured to be connected with the external detection module, and the output side is configured to be connected with the internal monitor module, the isolation and transfer module receives the first level detection current and outputs a second level detection current to the internal monitor module.

Abstract: A conductive rail joint comprises a left conductive rail (1), a middle rail (2), a right conductive rail (3), supporting plates (4), electric conductors (5) and conductive wires (6). The opposite end faces of the three rails are slant and parallel with each other. The supporting plates (4), the electric conductors (5) and the conductive wires (6) respectively consist of a left one and a right one. The two supporting plates are axial non-symmetrically mounted at the bottom of the corresponding conductive rails (1, 3) respectively. One end of each electric conductor (51, 52) is fixed to the corresponding supporting plate (41, 42) and the other end is suspended. Each of the two conductive wires (61, 62) is connected between the fixed end of the corresponding electric conductor (51, 52) and the suspended end of the other electric conductor (52, 51). The conductive wires (6) are loose after the connection.

Abstract: A multiple inverter and an active power filter system are disclosed in the invention, said multiple inverter can decrease the volume and harmonics, increase the efficiency and decrease the cost, and can be applied to various occasions. The technical scheme is: the filter assembly in the multiple inverter is installed at the output inductor of the multiple inverter for filtering the harmonics.

Abstract: An active isolated power supply with multiple outputs is provided. The power supply includes N transformers T1˜Tn connected to output terminals of AC source, the primary circuits of transformers T1˜Tn are connected in parallel with each other, wherein N is a positive integral number equals to or greater than 2, and N switching devices S1˜Sn or N?1 switching devices S1˜Sn?1 connected in series with the primary circuits of transformers T1˜Tn respectively, to restrict the current direction of the primary circuits of transformers T1˜Tn. Herein, N output power supplies isolated with each other are generated on the secondary sides of transformers T1˜Tn. Therefore, flow direction of current in the primary sides of the transformers is fixed by present invention, such that each transformer can accomplish magnetic reset in one operation period, thereby avoiding the occurrence of current circulation between the primary circuits.

Abstract: An angle grinder is provided including a radial fan assembly. The radial fan assembly is configured to direct exhaust radially outwardly and axially away from a user of the angle grinder. Brush card assemblies for an angle grinder are also provided. The brush card assemblies provide for the securing of brush cards to a field case of the angle grinder by the interface between the field case and brush cards. Additionally, a spindle lock mechanism and a safety mechanism for an angle grinder are provided.

Abstract: A conductive rail joint comprises a left conductive rail (1), a middle rail (2), a right conductive rail (3), supporting plates (4), electric conductors (5) and conductive wires (6). The opposite end faces of the three rails are slant and parallel with each other. The supporting plates (4), the electric conductors (5) and the conductive wires (6) respectively consist of a left one and a right one. The two supporting plates are axial non-symmetrically mounted at the bottom of the corresponding conductive rails (1, 3) respectively. One end of each electric conductor (51, 52) is fixed to the corresponding supporting plate (41, 42) and the other end is suspended. Each of the two conductive wires (61, 62) is connected between the fixed end of the corresponding electric conductor (51, 52) and the suspended end of the other electric conductor (52, 51). The conductive wires (6) are loose after the connection.

Abstract: An angle grinder is provided including a radial fan assembly. The radial fan assembly is configured to direct exhaust radially outwardly and axially away from a user of the angle grinder. Brush card assemblies for an angle grinder are also provided. The brush card assemblies provide for the securing of brush cards to a field case of the angle grinder by the interface between the field case and brush cards. Additionally, a spindle lock mechanism and a safety mechanism for an angle grinder are provided.

Abstract: An angle grinder is provided including a radial fan assembly. The radial fan assembly is configured to direct exhaust radially outwardly and axially away from a user of the angle grinder. Brush card assemblies for an angle grinder are also provided. The brush card assemblies provide for the securing of brush cards to a field case of the angle grinder by the interface between the field case and brush cards. Additionally, a spindle lock mechanism and a safety mechanism for an angle grinder are provided.

Abstract: An angle grinder is provided including a radial fan assembly. The radial fan assembly is configured to direct exhaust radially outwardly and axially away from a user of the angle grinder. Brush card assemblies for an angle grinder are also provided. The brush card assemblies provide for the securing of brush cards to a field case of the angle grinder by the interface between the field case and brush cards. Additionally, a spindle lock mechanism and a safety mechanism for an angle grinder are provided.

Abstract: Compositions having the general formula (Ca.sub.x Mg.sub.1-x)Zr.sub.4 (PO.sub.4).sub.6 where x is between 0.5 and 0.99 are produced by solid state and sol-gel processes. In a preferred embodiment, when x is between 0.5 and 0.8, the MgCZP materials have near-zero coefficients of thermal expansion. The MgCZPs of the present invention also show unusually low thermal conductivities, and are stable at high temperatures. Macrostructures formed from MgCZP are useful in a wide variety of high-temperature applications. In a preferred process, calcium, magnesium, and zirconium nitrate solutions have their pH adjusted to between 7 and 9 either before or after the addition of ammonium dihydrogen phosphate. After dehydration to a gel, and calcination at temperatures in excess of 850.degree. C. for approximately 16 hours, single phase crystalline MgCZP powders with particle sizes ranging from approximately 20 nm to 50 nm result. The MgCZP powders are then sintered at temperatures ranging from 1200.degree. C. to 1350.