Patents by Inventor Yasuhiro Kurahashi
Yasuhiro Kurahashi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 9453716Abstract: Provided are a method for measuring tool dimensions and a measurement device, whereby if a machine tool (10) cannot fit the overall outline of a tool (20) inside the field of vision (V) for an image from an imaging device (33), the field of vision (V) of the imaging device (33) is moved by relatively moving the imaging device (33) and the tool (20). In addition, the imaging device (33) can follow the outline (54) of the tool (20) by moving the field of vision (V), because the movement direction (53) for the field of vision (V) is determined on the basis of the partial outline (51) specified based on image data. In this way, even when measuring dimensions for a tool (20) with a larger diameter than the field of vision (V) of the imaging device (33), a partial outline (51) of a desired range, for example, is specified. An outline of a desired range for the tool (20) is extracted if a plurality of specified partial outlines (51) are combined.Type: GrantFiled: October 21, 2011Date of Patent: September 27, 2016Assignee: MAKINO MILLING MACHINE CO., LTD.Inventor: Yasuhiro Kurahashi
-
Patent number: 9329029Abstract: In the machine tool (10) pertaining to the present invention, an imaging device (33) takes an image of a tool (20) being moved in the feeding direction. Contour lines (51) are identified by means of the plurality of sets of image data generated from imaging. The movement trajectory (52) and the central axis (53) of the tool (20) are identified on the basis of the contour lines (51). When the movement trajectory (52) and the central axis (53) are offset, said offset can be used to correct the positioning of the tool (20) with the machine tool (10). As a result, the processing accuracy of a workpiece improves. Moreover, when the dimensions of a tool (20) that has a tilted posture are measured, it is possible to determine the actual tool diameter or the actual blade position in the tilted posture. The aforementioned blade position and tool diameter can be used to correct the positioning of the machine tool (10). Thus, the processing accuracy of the workpiece improves even more.Type: GrantFiled: October 27, 2011Date of Patent: May 3, 2016Assignee: Makino Milling Machine Co., Ltd.Inventor: Yasuhiro Kurahashi
-
Patent number: 9188437Abstract: In the machine tool (10) pertaining to the present invention, the contour lines (51) of a tool (20) are displayed on a display screen (S). When an operator measuring the dimensions traces a contour line (51) on the display screen (S) of a touch panel (45) with a finger, it is possible to automatically identify, on the display screen (S), the site to be measured (i.e., the contour line (51)) on the tool (20). In this way, an operator can measure the dimensions of the tool (20) in an extremely simple manner. Additionally, it is possible to automatically measure the tool diameter or the blade position of the tool (20) as the operator designates a specific position on the contour line (51) of the tool (20). Thus, with such a method for measuring the dimensions of the tool (20), it is possible to easily identify an unexpected site to be measured on a tool having complex contour lines, such as a multi-stage tool.Type: GrantFiled: October 27, 2011Date of Patent: November 17, 2015Assignee: Makino Milling Machine Co., Ltd.Inventor: Yasuhiro Kurahashi
-
Patent number: 8822229Abstract: The inventions provides a method for immunologically determining a keratan sulfate level which method includes bringing an anti-keratan sulfate monoclonal antibody into contact with a biological sample, the anti-keratan sulfate monoclonal antibody exhibiting a relative reaction specificity between keratan sulfate-I and keratan sulfate-II represented by IC50KS-I/KS-II of 0.4 to 5, to thereby provide a signal; and detecting keratan sulfate contained in the biological sample from the signal. On the basis of the method, the invention also provides a joint disease detection method and a method for assessing the effect of a remedy for a joint disease and a candidate substance therefor. Through these methods, a very small amount of keratan sulfate contained in a sample, can be determined. Particularly, these methods can determine, at high-sensitivity and high-specificity, the total keratan sulfate including keratan sulfate-I, which have been difficult to determine through a conventional technique.Type: GrantFiled: December 24, 2009Date of Patent: September 2, 2014Assignee: Seikagaku CorporationInventors: Shigeyuki Wakitani, Hiroshi Fujita, Takeshi Ishimaru, Koji Yamamoto, Yasuhiro Kurahashi, Junichi Onaya, Hiroyuki Masuda
-
Patent number: 8557536Abstract: An object of the present invention is to provide a detection method capable of detecting articular cartilage degeneration or damage in which the abnormality cannot be detected in a radiograph in a simple method and with high accuracy, a method of evaluating the rate of progression of articular cartilage degeneration or damage, and the like. The present invention as a means for achieving the object provides a method of detecting articular cartilage degeneration or damage which cannot be detected in a radiograph, by using the concentration of keratan sulfate in a sample derived from blood as an index, and the like. Further, the present invention provides a method of evaluating the rate of progression of articular cartilage degeneration or damage by using the concentration of keratan sulfate in a sample derived from blood as an index, and the like.Type: GrantFiled: February 5, 2008Date of Patent: October 15, 2013Assignee: Seikagaku CorporationInventors: Shigeyuki Wakitani, Masashi Nawata, Kyosuke Miyazaki, Hiroyuki Masuda, Hiroshi Fujita, Yasuhiro Kurahashi
-
Publication number: 20130222580Abstract: In the machine tool (10) pertaining to the present invention, the contour lines (51) of a tool (20) are displayed on a display screen (S). When an operator measuring the dimensions traces a contour line (51) on the display screen (S) of a touch panel (45) with a finger, it is possible to automatically identify, on the display screen (S), the site to be measured (i.e., the contour line (51)) on the tool (20). In this way, an operator can measure the dimensions of the tool (20) in an extremely simple manner. Additionally, it is possible to automatically measure the tool diameter or the blade position of the tool (20) as the operator designates a specific position on the contour line (51) of the tool (20). Thus, with such a method for measuring the dimensions of the tool (20), it is possible to easily identify an unexpected site to be measured on a tool having complex contour lines, such as a multi-stage tool.Type: ApplicationFiled: October 27, 2011Publication date: August 29, 2013Applicant: MAKINO MILLING MACHINE CO., LTD.Inventor: Yasuhiro Kurahashi
-
Publication number: 20130208286Abstract: In the machine tool (10) pertaining to the present invention, an imaging device (33) takes an image of a tool (20) being moved in the feeding direction. Contour lines (51) are identified by means of the plurality of sets of image data generated from imaging. The movement trajectory (52) and the central axis (53) of the tool (20) are identified on the basis of the contour lines (51). When the movement trajectory (52) and the central axis (53) are offset, said offset can be used to correct the positioning of the tool (20) with the machine tool (10). As a result, the processing accuracy of a workpiece improves. Moreover, when the dimensions of a tool (20) that has a tilted posture are measured, it is possible to determine the actual tool diameter or the actual blade position in the tilted posture. The aforementioned blade position and tool diameter can be used to correct the positioning of the machine tool (10). Thus, the processing accuracy of the workpiece improves even more.Type: ApplicationFiled: October 27, 2011Publication date: August 15, 2013Applicant: Makino Milling Machine Co., LtdInventor: Yasuhiro Kurahashi
-
Publication number: 20130176429Abstract: Provided are a method for measuring tool dimensions and a measurement device, whereby if a machine tool (10) cannot fit the overall outline of a tool (20) inside the field of vision (V) for an image from an imaging device (33), the field of vision (V) of the imaging device (33) is moved by relatively moving the imaging device (33) and the tool (20). In addition, the imaging device (33) can follow the outline (54) of the tool (20) by moving the field of vision (V), because the movement direction (53) for the field of vision (V) is determined on the basis of the partial outline (51) specified based on image data. In this way, even when measuring dimensions for a tool (20) with a larger diameter than the field of vision (V) of the imaging device (33), a partial outline (51) of a desired range, for example, is specified. An outline of a desired range for the tool (20) is extracted if a plurality of specified partial outlines (51) are combined.Type: ApplicationFiled: October 21, 2011Publication date: July 11, 2013Applicant: MAKINO MILLING MACHINE CO., LTD.Inventor: Yasuhiro Kurahashi
-
Publication number: 20110318759Abstract: The inventions provides a method for immunologically determining a keratan sulfate level which method includes bringing an anti-keratan sulfate monoclonal antibody into contact with a biological sample, the anti-keratan sulfate monoclonal antibody exhibiting a relative reaction specificity between keratan sulfate-I and keratan sulfate-II represented by IC50KS-I/KS-II of 0.4 to 5, to thereby provide a signal; and detecting keratan sulfate contained in the biological sample from the signal. On the basis of the method, the invention also provides a joint disease detection method and a method for assessing the effect of a remedy for a joint disease and a candidate substance therefor. Through these methods, a very small amount of keratan sulfate contained in a sample, can be determined. Particularly, these methods can determine, at high-sensitivity and high-specificity, the total keratan sulfate including keratan sulfate-I, which have been difficult to determine through a conventional technique.Type: ApplicationFiled: December 24, 2009Publication date: December 29, 2011Applicant: SEIKAGAKU CORPORATIONInventors: Shigeyuki Wakitani, Hiroshi Fujita, Takeshi Ishimaru, Koji Yamamoto, Yasuhiro Kurahashi, Junichi Onaya, Hiroyuki Masuda
-
Publication number: 20110151492Abstract: An object of the present invention is to provide a detection method capable of detecting articular cartilage degeneration or damage in which the abnormality cannot be detected in a radiograph in a simple method and with high accuracy, a method of evaluating the rate of progression of articular cartilage degeneration or damage, and the like. The present invention as a means for achieving the object provides a method of detecting articular cartilage degeneration or damage which cannot be detected in a radiograph, by using the concentration of keratan sulfate in a sample derived from blood as an index, and the like. Further, the present invention provides a method of evaluating the rate of progression of articular cartilage degeneration or damage by using the concentration of keratan sulfate in a sample derived from blood as an index, and the like.Type: ApplicationFiled: February 5, 2008Publication date: June 23, 2011Applicant: SEIKAGAKU CORPORATIONInventors: Shigeyuki Wakitani, Masashi Nawata, Kyosuke Miyazaki, Hiroyuki Masuda, Hiroshi Fujita, Yasuhiro Kurahashi
-
Patent number: 7331739Abstract: A wear amount of a working tool T during the machining of a workpiece is estimated during the machining, and a positional command generated in accordance with a predetermined machining program is sequentially corrected during the machining based on the estimated wear amount of the working tool T. The workpiece W is machined in accordance with the corrected positional command. Also, the wear amount of the working tool T upon the interruption of the machining operation is calculated, and the positional command generated in accordance with the predetermined machining program is corrected based on the calculated wear amount of the working tool so that a tool edge position of the working tool T upon the interruption of the machining operation coincides with the tool edge position of the working tool T upon the restart of the machining operation when the machining operation is restarted at a position where the machining operation has been interrupted.Type: GrantFiled: August 12, 2004Date of Patent: February 19, 2008Assignee: Makino Milling Machine Co., Ltd.Inventors: Jun Yoshida, Akira Kawana, Yasuhiro Kurahashi
-
Publication number: 20060251484Abstract: A wear amount of a working tool T during the machining of a workpiece is estimated during the machining, and a positional command generated in accordance with a predetermined machining program is sequentially corrected during the machining based on the estimated wear amount of the working tool T. The workpiece W is machined in accordance with the corrected positional command. Also, the wear amount of the working tool T upon the interruption of the machining operation is calculated, and the positional command generated in accordance with the predetermined machining program is corrected based on the calculated wear amount of the working tool so that a tool edge position of the working tool T upon the interruption of the machining operation coincides with the tool edge position of the working tool T upon the restart of the machining operation when the machining operation is restarted at a position where the machining operation has been interrupted.Type: ApplicationFiled: August 12, 2004Publication date: November 9, 2006Inventors: Jun Yoshida, Akira Kawana, Yasuhiro Kurahashi
-
Patent number: 6973738Abstract: A method of measuring the position of the cutting edge of a tool T mounted to a spindle 14 of an NC machine tool includes steps of measuring the dimension of the center of an end surface of the spindle 14 relative a reference position in a machine coordinate system of the machine tool in the axial directions of the X-, Y- and Z-axes, measuring the dimensions of the position of the cutting edge of the tool T mounted to the spindle 14 relative to the center of the end surface of the spindle 14 in the axial directions of the X-, Y- and Z-axes, obtaining the dimensions of the position of the cutting edge of the tool T mounted to the spindle 14 relative to the reference position in the machine coordinate system through a calculation on the basis of the relative dimensions of the center of the end surface of the spindle 14 in the machine coordinate system and the dimensions of the position of the cutting edge of the tool T mounted to the spindle 14.Type: GrantFiled: July 18, 2001Date of Patent: December 13, 2005Assignee: Makino Milling Machine Co., Ltd.Inventors: Kiyoshi Kaneda, Yasuhiro Kurahashi
-
Patent number: 6602859Abstract: A photocurable hyaluronic acid derivative of the present invention comprises hyaluronic acid and a photoreactive crosslinking group bonded thereto, wherein a 1.0 wt. % aqueous solution of the photocurable hyaluronic acid derivative obtained by dissolving the solid photocurable hyaluronic acid derivative in an aqueous solvent, is capable of passing through a porous filter having a pore size of 0.45 &mgr;m and a diameter of 25 mm at a rate of not less than 2 ml/minute at 24° C. under a pressure of 5.0 Kg/cm2; and a process for producing the photocurable hyaluronic acid derivative; and a photocured crosslinked-hyaluronic acid derivative; a medical material using the photoreactive hyaluronic acid derivative and a medical material using the photocured crosslinked-hyaluronic acid derivative.Type: GrantFiled: December 18, 2001Date of Patent: August 5, 2003Assignee: Seikagaku CorporationInventors: Kenji Miyamoto, Yasuhiro Kurahashi, Hiroki Kano
-
Publication number: 20020189120Abstract: A method of measuring the position of the cutting edge of a tool T mounted to a spindle 14 of an NC machine tool includes steps of measuring the dimension of the center of an end surface of the spindle 14 relative a reference position in a machine coordinate system of the machine tool in the axial directions of the X-, Y- and Z-axes, measuring the dimensions of the position of the cutting edge of the tool T mounted to the spindle 14 relative to the center of the end surface of the spindle 14 in the axial directions of the X-, Y- and Z-axes, obtaining the dimensions of the position of the cutting edge of the tool T mounted to the spindle 14 relative to the reference position in the machine coordinate system through a calculation on the basis of the relative dimensions of the center of the end surface of the spindle 14 in the machine coordinate system and the dimensions of the position of the cutting edge of the tool T mounted to the spindle 14.Type: ApplicationFiled: June 17, 2002Publication date: December 19, 2002Inventors: Kiyoshi Kaneda, Yasuhiro Kurahashi
-
Publication number: 20020143121Abstract: A photocurable hyaluronic acid derivative of the present invention comprises hyaluronic acid and a photoreactive crosslinking group bonded thereto, wherein a 1.0 wt. % aqueous solution of the photocurable hyaluronic acid derivative obtained by dissolving the solid photocurable hyaluronic acid derivative in an aqueous solvent, is capable of passing through a porous filter having a pore size of 0.45 &mgr;m and a diameter of 25 mm at a rate of not less than 2 ml/minute at 24° C. under a pressure of 5.0 Kg/cm2; and a process for producing the photocurable hyaluronic acid derivative; and a photocured crosslinked-hyaluronic acid derivative; a medical material using the photoreactive hyaluronic acid derivative and a medical material using the photocured crosslinked-hyaluronic acid derivative.Type: ApplicationFiled: December 18, 2001Publication date: October 3, 2002Inventors: Kenji Miyamoto, Yasuhiro Kurahashi, Hiroki Kano