Patents by Inventor Yasuhiro Mitsumoto
Yasuhiro Mitsumoto has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 9884149Abstract: An object of the present invention is to provide an infusion preparation in which the Maillard reaction between an amino acid and a reducing sugar does not occur during storage and the size of fat particles in the fat emulsion does not increase during storage, and in which various types of vitamins can be incorporated in a stable manner, in spite of the fact that it is a two-chamber infusion preparation. Furthermore, even if only one of the infusions (of the infusion preparation) is administered, the patient is unlikely to develop hyperkalemia, vascular pain, or phlebitis. The present invention provides an infusion preparation containing two chambers separated by a partition that can be communicably opened, wherein a first chamber contains a first-chamber infusion containing a sugar and a fat emulsion, a second chamber contains a second-chamber infusion containing an amino acid and an electrolyte, the first-chamber infusion is substantially free of potassium, and has a relative osmotic pressure of 2.0 to 3.Type: GrantFiled: June 20, 2017Date of Patent: February 6, 2018Assignee: OTSUKA PHARMACEUTICAL FACTORY, INC.Inventors: Seiji Tani, Yasuhiro Mitsumoto
-
Publication number: 20170304530Abstract: An object of the present invention is to provide an infusion preparation in which the Maillard reaction between an amino acid and a reducing sugar does not occur during storage and the size of fat particles in the fat emulsion does not increase during storage, and in which various types of vitamins can be incorporated in a stable manner, in spite of the fact that it is a two-chamber infusion preparation. Furthermore, even if only one of the infusions (of the infusion preparation) is administered, the patient is unlikely to develop hyperkalemia, vascular pain, or phlebitis. The present invention provides an infusion preparation containing two chambers separated by a partition that can be communicably opened, wherein a first chamber contains a first-chamber infusion containing a sugar and a fat emulsion, a second chamber contains a second-chamber infusion containing an amino acid and an electrolyte, the first-chamber infusion is substantially free of potassium, and has a relative osmotic pressure of 2.0 to 3.Type: ApplicationFiled: June 20, 2017Publication date: October 26, 2017Applicant: OTSUKA PHARMACEUTICAL FACTORY, INC.Inventors: Seiji TANI, Yasuhiro MITSUMOTO
-
Patent number: 9687600Abstract: An object of the present invention is to provide an infusion preparation in which the Maillard reaction between an amino acid and a reducing sugar does not occur during storage and the size of fat particles in the fat emulsion does not increase during storage, and in which various types of vitamins can be incorporated in a stable manner, in spite of the fact that it is a two-chamber infusion preparation. Furthermore, even if only one of the infusions (of the infusion preparation) is administered, the patient is unlikely to develop hyperkalemia, vascular pain, or phlebitis. The present invention provides an infusion preparation containing two chambers separated by a partition that can be communicably opened, wherein a first chamber contains a first-chamber infusion containing a sugar and a fat emulsion, a second chamber contains a second-chamber infusion containing an amino acid and an electrolyte, the first-chamber infusion is substantially free of potassium, and has a relative osmotic pressure of 2.0 to 3.Type: GrantFiled: December 18, 2015Date of Patent: June 27, 2017Assignee: OTSUKA PHARMACEUTICAL FACTORY, INC.Inventors: Seiji Tani, Yasuhiro Mitsumoto
-
Patent number: 9446184Abstract: An object of the present invention is to provide an infusion preparation in which the Maillard reaction between an amino acid and a reducing sugar does not occur during storage and the size of fat particles in the fat emulsion does not increase during storage, and in which various types of vitamins can be incorporated in a stable manner, in spite of the fact that it is a two-chamber infusion preparation. Furthermore, even if only one of the infusions (of the infusion preparation) is administered, the patient is unlikely to develop hyperkalemia, vascular pain, or phlebitis. The present invention provides an infusion preparation containing two chambers separated by a partition that can be communicably opened, wherein a first chamber contains a first-chamber infusion containing a sugar and a fat emulsion, a second chamber contains a second-chamber infusion containing an amino acid and an electrolyte, the first-chamber infusion is substantially free of potassium, and has a relative osmotic pressure of 2.0 to 3.Type: GrantFiled: November 28, 2011Date of Patent: September 20, 2016Assignee: OTSUKA PHARMACEUTICAL FACTORY, INC.Inventors: Seiji Tani, Yasuhiro Mitsumoto
-
Publication number: 20160101231Abstract: An object of the present invention is to provide an infusion preparation in which the Maillard reaction between an amino acid and a reducing sugar does not occur during storage and the size of fat particles in the fat emulsion does not increase during storage, and in which various types of vitamins can be incorporated in a stable manner, in spite of the fact that it is a two-chamber infusion preparation. Furthermore, even if only one of the infusions (of the infusion preparation) is administered, the patient is unlikely to develop hyperkalemia, vascular pain, or phlebitis. The present invention provides an infusion preparation containing two chambers separated by a partition that can be communicably opened, wherein a first chamber contains a first-chamber infusion containing a sugar and a fat emulsion, a second chamber contains a second-chamber infusion containing an amino acid and an electrolyte, the first-chamber infusion is substantially free of potassium, and has a relative osmotic pressure of 2.0 to 3.Type: ApplicationFiled: December 18, 2015Publication date: April 14, 2016Applicant: OTSUKA PHARMACEUTICAL FACTORY, INC.Inventors: Seiji TANI, Yasuhiro MITSUMOTO
-
Publication number: 20130313261Abstract: An object of the present invention is to provide an infusion preparation in which the Maillard reaction between an amino acid and a reducing sugar does not occur during storage and the size of fat particles in the fat emulsion does not increase during storage, and in which various types of vitamins can be incorporated in a stable manner, in spite of the fact that it is a two-chamber infusion preparation. Furthermore, even if only one of the infusions (of the infusion preparation) is administered, the patient is unlikely to develop hyperkalemia, vascular pain, or phlebitis. The present invention provides an infusion preparation containing two chambers separated by a partition that can be communicably opened, wherein a first chamber contains a first-chamber infusion containing a sugar and a fat emulsion, a second chamber contains a second-chamber infusion containing an amino acid and an electrolyte, the first-chamber infusion is substantially free of potassium, and has a relative osmotic pressure of 2.0 to 3.Type: ApplicationFiled: November 28, 2011Publication date: November 28, 2013Applicant: OTSUKA PHARMACEUTICAL FACTORY, INC.Inventors: Seiji Tani, Yasuhiro Mitsumoto
-
Patent number: 8404274Abstract: There is provided an aseptic combination preparation to be mixed at the time of use, characterized in that the same medicinal ingredients are divided and preserved in two or more chambers. The aseptic combination preparations according to the present invention are a mixing type at the time of their use and are useful as infusions, various dialysis fluids, intraocular perfusion/washing solutions, coronary perfusion solutions, myocardial protective solutions, peritoneal lavage solutions, solutions for organ preservations, etc., which can eliminate adverse effects caused by medical error on a living body.Type: GrantFiled: June 4, 2004Date of Patent: March 26, 2013Assignee: Otsuka Pharmaceutical Factory, Inc.Inventors: Nobuaki Sumiyoshi, Yasuhiro Mitsumoto, Shigeaki Arita, Seiji Tani, Masaru Kobayashi
-
Patent number: 8273717Abstract: An inhibitor for perioperative blood sugar elevation characterized by containing a branched amino acid, a compound which can be converted into a branched amino acid in vivo or a compound to which an amino group has been transferred from a branched amino acid. This inhibitor for perioperative blood sugar elevation is useful as a drug which is safe to the living body including human, inhibits abnormal elevation in the blood glucose level caused by anesthesia, surgery, etc., and enables proper blood sugar control, when administered to a perioperative patient.Type: GrantFiled: February 5, 2004Date of Patent: September 25, 2012Assignee: Otsuka Pharmaceutical Factory, Inc.Inventors: Ippei Yamaoka, Yasuhiro Mitsumoto, Masako Doi, Tetsuya Fukunaga, Mitsuo Nakayama
-
Patent number: 7984739Abstract: It is intended to provide a method of producing thermally fused synthetic resin members for medical use which makes it possible that, in the case of thermally fusing synthetic resin members for medical use, for example, a relatively soft thermoplastic tube constituting an AVF needle with another part being harder than the tube such as a needle base (hub) of a wing needle, or a part provided with a fitting connector being harder than the tube (for example, a blood circuit, an extension tube, an infusion set or the like), the connecting parts of the thermoplastic tube member and the other member harder than the thermoplastic tube member can be quickly and uniformly thermal-fused and the production process can be automatically and continuously performed while keeping a high productivity; and a production apparatus therefor.Type: GrantFiled: July 26, 2005Date of Patent: July 26, 2011Assignee: JMS Co., Ltd.Inventors: Susumu Hongo, Takafumi Kiyono, Youzou Katsura, Yasuhiro Mitsumoto, Shingo Henmi
-
Publication number: 20090038756Abstract: It is intended to provide a method of producing thermally fused synthetic resin members for medical use which makes it possible that, in the case of thermally fusing synthetic resin members for medical use, for example, a relatively soft thermoplastic tube constituting an AVF needle with another part being harder than the tube such as a needle base (hub) of a wing needle, or a part provided with a fitting connector being harder than the tube (for example, a blood circuit, an extension tube, an infusion set or the like), the connecting parts of the thermoplastic tube member and the other member harder than the thermoplastic tube member can be quickly and uniformly thermal-fused and the production process can be automatically and continuously performed while keeping a high productivity; and a production apparatus therefor.Type: ApplicationFiled: July 26, 2005Publication date: February 12, 2009Inventors: Susumu Hongo, Takafumi Kiyono, Youzou Katsura, Yasuhiro Mitsumoto, Shingo Henmi
-
Publication number: 20060211631Abstract: The infusion preparation for peripheral parenteral administration comprises an infusion (A) containing glucose with 80 to 200 g/L concentration, and an infusion (B) containing amino acid with 50 to 150 g/L concentration. The infusion (A) and the infusion (B) are separately put into a vessel that is divided with an openable partition means. The infusion (A) does not contain sulfite, has titratable acidity of 1 or less, contains vitamin B1 and is adjusted to pH 3 to 5. The infusion (B) is adjusted to pH 6.5 to 8. After mixing the both infusions, the mixture has pH 6 to 7.5 and titratable acidity of 5 to 10.Type: ApplicationFiled: May 14, 2004Publication date: September 21, 2006Inventors: Yasuhiro Mitsumoto, Shigeaki Arita, Seiji Tani, Nobuaki Sumiyoshi
-
Publication number: 20060154873Abstract: There is provided an aseptic combination preparation to be mixed at the time of use, characterized in that the same medicinal ingredients are divided and preserved in two or more chambers. The aseptic combination preparations according to the present invention are a mixing type at the time of their use and are useful as infusions, various dialysis fluids, intraocular perfusion/washing solutions, coronary perfusion solutions, myocardial protective solutions, peritoneal lavage solutions, solutions for organ preservations, etc., which can eliminate adverse effects caused by medical error on a living body.Type: ApplicationFiled: June 4, 2004Publication date: July 13, 2006Inventors: Nobuaki Sumiyoshi, Yasuhiro Mitsumoto, Shigeaki Arita, Seiji Tani, Masaru Kobayashi
-
Publication number: 20060116426Abstract: An inhibitor for perioperative blood sugar elevation characterized by containing a branched amino acid, a compound which can be converted into a branched amino acid in vivo or a compound to which an amino group has been transferred from a branched amino acid. This inhibitor for perioperative blood sugar elevation is useful as a drug which is safe to the living body including human, inhibits abnormal elevation in the blood glucose level caused by anesthesia, surgery, etc., and enables proper blood sugar control, when administered to a perioperative patient.Type: ApplicationFiled: February 5, 2004Publication date: June 1, 2006Inventors: Ippei Yamaoka, Yasuhiro Mitsumoto, Masako Doi, Tetsuya Fukunaga, Mitsuo Nakayama