Patents by Inventor Yasuhiro Nishitani
Yasuhiro Nishitani has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9334289Abstract: The present invention provides a novel compound which has a wide antimicrobial spectrum, and in particular exhibits potent antimicrobial activity against beta-lactamase producing Gram negative bacteria. Specifically, the present invention provides a compound of the formula (I): wherein each symbol is as defined in the specification, or an amino-protected compound when the amino group is present on the ring in the 7-side chain, or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition comprising the same.Type: GrantFiled: April 25, 2012Date of Patent: May 10, 2016Assignee: SHIONOGI & CO., LTD.Inventors: Yasuhiro Nishitani, Toshiaki Aoki, Jun Sato, Kenji Yamawaki, Katsuki Yokoo, Masayuki Sano
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Patent number: 9242999Abstract: The present invention provides a novel compound which has a broad antibacterial spectrum and particularly exhibits a high antibacterial activity on ?-lactamase-producing gram-negative bacteria. Specifically provided are: a compound represented by formula (I) wherein the meaning of each symbol is as defined in the description, an amino-group-protected form of a type of the compound which has the amino group on a ring in a position-7 side chain, or a pharmaceutically acceptable salt of the compound or the amino-group-protected form; and a pharmaceutical composition containing the compound, the amino-group-protected form or the pharmaceutically acceptable salt.Type: GrantFiled: June 26, 2012Date of Patent: January 26, 2016Assignee: SHIONOGI & CO., LTD.Inventors: Yasuhiro Nishitani, Toshiaki Aoki
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Patent number: 9238657Abstract: The present disclosure describes Cephem compounds of the formula: wherein, X is N, CH or C—Cl; T is S or the like; A and G are lower alkylene or the like; B is a single bond or the like; D is optionally present, and when present is, —NR7—, —CO—, —CO—NR7—, —NR7—CO—, —NR7—CO—NR7—, or the like; F is optionally present, and when present is or phenylene; R3 and R4 are —OR8; R5 and R6 each is independently hydrogen, halogen, nitrile, or —OR8; or an ester at the carboxyl at the 7-position side chain or at the 4-position, a compound protected at the amino on the ring in the 7-side chain, a pharmaceutically acceptable salt, or a solvate thereof, which have a wide antimicrobial spectrum and have potent antimicrobial activity against beta-lactamase producing Gram negative bacteria.Type: GrantFiled: October 27, 2009Date of Patent: January 19, 2016Assignee: SHIONOGI & CO., LTD.Inventors: Yasuhiro Nishitani, Kenji Yamawaki, Yusuke Takeoka, Hideki Sugimoto, Shinya Hisakawa, Toshiaki Aoki
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Patent number: 8933012Abstract: The present invention provides a novel glycopeptide antibiotic derivative.Type: GrantFiled: May 25, 2007Date of Patent: January 13, 2015Assignee: Shionogi & Co., Ltd.Inventors: Yasuhiro Nishitani, Osamu Yoshida, Tsutomu Iwaki, Issei Kato
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Publication number: 20140114060Abstract: The present invention provides a novel compound which has a broad antibacterial spectrum and particularly exhibits a high antibacterial activity on ?-lactamase-producing gram-negative bacteria. Specifically provided are: a compound represented by formula (I) wherein the meaning of each symbol is as defined in the description, an amino-group-protected form of a type of the compound which has the amino group on a ring in a position-7 side chain, or a pharmaceutically acceptable salt of the compound or the amino-group-protected form; and a pharmaceutical composition containing the compound, the amino-group-protected form or the pharmaceutically acceptable salt.Type: ApplicationFiled: June 26, 2012Publication date: April 24, 2014Applicant: SHIONOGI & CO., LTD.Inventors: Yasuhiro Nishitani, Toshiaki Aoki
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Publication number: 20140088302Abstract: The present invention provides a novel compound which has a wide antimicrobial spectrum, and in particular exhibits potent antimicrobial activity against beta-lactamase producing Gram negative bacteria. Specifically, the present invention provides a compound of the formula (I): wherein each symbol is as defined in the specification, or an amino-protected compound when the amino group is present on the ring in the 7-side chain, or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition comprising the same.Type: ApplicationFiled: April 25, 2012Publication date: March 27, 2014Applicant: SHIONOGI & CO., LTD.Inventors: Yasuhiro Nishitani, Toshiaki Aoki, Jun Sato, Kenji Yamawaki, Katsuki Yokoo, Masayuki SANO
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Publication number: 20110190254Abstract: The present invention provides Cephem compounds which have a wide antimicrobial spectrum and have potent antimicrobial activity against beta-lactamase producing Gram negative bacteria as follows: A compound of the formula: wherein, X is N, CH or C—Cl; T is S or the like; A and G are lower alkylene or the like; B is a single bond or the like; D is a single bond, —NR7—, —CO—, —CO—NR7—, —NR7—CO—, —NR7—CO—NR7—, or the like; E is optionally substituted lower alkylene; F is a single bond or optionally substituted phenylene; R3, R4, R5 and R6 each is independently hydrogen, halogene, nitrile, or the like; or an ester, a compound protected at the amino on the ring in the 7-side chain, a pharmaceutically acceptable salt, or a solvate thereof.Type: ApplicationFiled: October 27, 2009Publication date: August 4, 2011Applicant: SHIONOGI & CO., LTD.Inventors: Yasuhiro Nishitani, Kenji Yamawaki, Yusuke Takeoka, Hideki Sugimoto, Shinya Hisakawa, Toshiaki Aoki
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Patent number: 7696354Abstract: A compound of the formula: (wherein, T is S, SO or O; X is halogen, CN, carbamoyl optionally substituted with lower alkyl, lower alkyl, lower alkoxy, or lower alkylthio; A is substituted lower alkylene (wherein the substituent is optionally substituted mono lower alkyl, optionally substituted lower alkylidene, or optionally substituted lower alkylene); Z+ is an optionally substituted, a cation and an N atom-containing heterocyclic group), ester, amino-protected compound wherein the amino bonds to a thiazole ring at the 7-position, or pharmaceutically acceptable salt or solvate thereof.Type: GrantFiled: April 9, 2008Date of Patent: April 13, 2010Assignee: Shionogi & Co., Ltd.Inventors: Yasuhiro Nishitani, Yoshinori Yamano
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Publication number: 20090286717Abstract: The present invention provides a novel glycopeptide antibiotic derivative.Type: ApplicationFiled: May 25, 2007Publication date: November 19, 2009Inventors: Yasuhiro Nishitani, Osamu Yoshida, Tsutomu Iwaki, Issei Kato
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Publication number: 20090131655Abstract: A compound of the formula: (wherein, T is S, SO or O; X is halogen, CN, carbamoyl optionally substituted with lower alkyl, lower alkyl, lower alkoxy, or lower alkylthio; A is substituted lower alkylene (wherein the substituent is optionally substituted mono lower alkyl, optionally substituted lower alkylidene, or optionally substituted lower alkylene) Z+ is an optionally substituted, a cation and an N atom-containing heterocyclic group), ester, amino-protected compound wherein the amino bonds to a thiazole ring at the 7-position, or pharmaceutically acceptable salt or solvate thereof.Type: ApplicationFiled: April 9, 2008Publication date: May 21, 2009Inventors: Yasuhiro Nishitani, Yoshinori Yamano
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Patent number: 7384928Abstract: A compound of the formula: (wherein, T is S, SO or O; X is halogen, CN, carbamoyl optionally substituted with lower alkyl, lower alkyl, lower alkoxy, or lower alkylthio; A is substituted lower alkylene (wherein the substituent is optionally substituted mono lower alkyl, optionally substituted lower alkylidene, or optionally substituted lower alkylene); Z+ is an optionally substituted, a cation and an N atom-containing heterocyclic group), ester, amino-protected compound wherein the amino bonds to a thiazole ring at the 7-position, or pharmaceutically acceptable salt or solvate thereof.Type: GrantFiled: March 18, 2003Date of Patent: June 10, 2008Assignee: Shionogi & Co., Ltd.Inventors: Yasuhiro Nishitani, Yoshinori Yamano
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Publication number: 20070219191Abstract: A compound of Formula 1: (wherein A is optionally substituted lower alkylene (substituent: mono- or di-lower alkyl, lower alkylidene, or lower alkylene having two or more carbons); Z+ is either of the groups shown below: (wherein R1 and R2 are each independently hydrogen, optionally substituted amino lower alkyl, optionally substituted aminocycloalkyl, optionally substituted cyclic amino, or optionally substituted cyclic amino lower alkyl; R9 is hydrogen or lower alkyl, or R1 and R9 taken together with an adjacent N atom may form optionally substituted cyclic amino; R3 is hydrogen or amino; X is N or CR4 (R4 is hydrogen or optionally substituted lower alkyl)), a pharmaceutically acceptable salt or a solvate thereof.Type: ApplicationFiled: March 3, 2005Publication date: September 20, 2007Inventors: Yasuhiro Nishitani, Tatsuro Yasukata, Kenji Yamawaki
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Patent number: 7116355Abstract: Printing light beams from a printing head that is driven based on image data are used for recording a latent image in a predetermined exposure area on an instant film. The instant film is exposed through an exposure opening formed through a case of a film pack. The printing head projects the printing light beams linearly along a main scan direction while moving in a sub scan direction perpendicular to the main scan direction. An illumination range of the printing light beams is determined to be wider than the exposure area in the main and sub scan directions, in consideration of clearances between the case and the instant film. So the entire exposure area is exposed even where the instant film deviates inside the case. A light-shielding housing for covering up a moving range of the printing head in a light-tight fashion is formed integrally with a pack loading chamber for loading the film pack.Type: GrantFiled: April 12, 1999Date of Patent: October 3, 2006Assignee: Fuji Photo Film Co., Ltd.Inventors: Hiroshi Omura, Yasuhiro Nishitani, Ko Aosaki, Yoshio Sugano
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Publication number: 20050179731Abstract: Printing light beams from a printing head that is driven based on image data are used for recording a latent image in a predetermined exposure area on an instant film. The instant film is exposed through an exposure opening formed through a case of a film pack. The printing head projects the printing light beams linearly along a main scan direction while moving in a sub scan direction perpendicular to the main scan direction. An illumination range of the printing light beams is determined to be wider than the exposure area in the main and sub scan directions, in consideration of clearances between the case and the instant film. So the entire exposure area is exposed even where the instant film deviates inside the case. A light-shielding housing for covering up a moving range of the printing head in a light-tight fashion is formed integrally with a pack loading chamber for loading the film pack.Type: ApplicationFiled: April 12, 2005Publication date: August 18, 2005Applicant: FUJI PHOTO FILM CO., LTD.Inventors: Hiroshi Omura, Yasuhiro Nishitani, Ko Aosaki, Yoshio Sugano
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Publication number: 20050153950Abstract: A compound of the formula: (wherein, T is S, SO or O; X is halogen, CN, carbamoyl optionally substituted with lower alkyl, lower alkyl, lower alkoxy, or lower alkylthio; A is substituted lower alkylene (wherein the substituent is optionally substituted mono lower alkyl, optionally substituted lower alkylidene, or optionally substituted lower alkylene); Z+ is an optionally substituted, a cation and an N atom-containing heterocyclic group), ester, amino-protected compound wherein the amino bonds to a thiazole ring at the 7-position, or pharmaceutically acceptable salt or solvate thereof.Type: ApplicationFiled: March 18, 2003Publication date: July 14, 2005Applicant: SHIONOGI & CO., LTD.Inventors: Yasuhiro Nishitani, Yoshinori Yamano
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Patent number: 6801718Abstract: Modes of a camera are classified into groups according to their type. On an LCD panel, the different groups are displayed on different rows, and modes to be selected out of each group are displayed in different columns. Group selection is accomplished by vertically manipulating a selector button, and mode selection out of each group is accomplished by laterally manipulating the selector button. This makes possible displaying of selectable modes classified by group on the LCD panel in a way perceivable at a glance. Furthermore, the choice of a group and that of a mode within each group are matched in the mode display arrangement to facilitate the operation for mode selection.Type: GrantFiled: May 21, 2002Date of Patent: October 5, 2004Assignees: Fuji Photo Optical Co., Ltd., Fuji Photo Film Co., Ltd.Inventors: Takao Umetsu, Haruo Onozuka, Minoru Ishiguro, Yasuhiro Nishitani, Kunihiko Tanaka, Makoto Akiba
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Patent number: 6800621Abstract: A cefem compound of the formula (I) shows wide antibacterial spectrum against various pathogenic bacteria including MRSA. wherein, X is N or CY and Y is H or halogen; R1 is amino or protected amino; R2 is hydrogen or optionally substituted lower alkyl etc.; R3 is hydrogen etc.; R4 is hydrogen, optionally substituted lower alkyl, or optionally substituted N-containing heterocyclic group etc.; R5 is hydrogen etc.; and a wavy line means syn- or anti-isomerism or a mixture thereof.Type: GrantFiled: December 13, 2002Date of Patent: October 5, 2004Assignee: Shionogi & Co., Ltd.Inventors: Yasuhiro Nishitani, Hikaru Itani, Tadashi Irie
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Publication number: 20030149014Abstract: A cefem compound of the formula (I) shows wide antibacterial spectrum against various pathogenic bacteria including MRSA.Type: ApplicationFiled: December 13, 2002Publication date: August 7, 2003Applicant: Shionogi & Co., Ltd.Inventors: Yasuhiro Nishitani, Hikaru Itani, Tadashi Irie
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Patent number: 6518263Abstract: A cefem compound of the formula (I) shows wide antibacterial spectrum against various pathogenic bacteria including MRSA. wherein, X is N or CY and Y is H or halogen; R1 is amino or protected amino; R2 is hydrogen or optionally substituted lower alkyl etc.; R3 is hydrogen etc.; R4 is hydrogen, optionally substituted lower alkyl, or optionally substituted N-containing heterocyclic group etc.; R5 is hydrogen etc.; and a wavy line means syn- or anti-isomerism or a mixture thereof.Type: GrantFiled: May 25, 2001Date of Patent: February 11, 2003Assignee: Shionogi & Co., Ltd.Inventors: Yasuhiro Nishitani, Hikaru Itani, Tadashi Irie
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Publication number: 20020176709Abstract: Modes of a camera are classified into groups according to their type. On an LCD panel, the different groups are displayed on different rows, and modes to be selected out of each group are displayed in different columns. Group selection is accomplished by vertically manipulating a selector button, and mode selection out of each group is accomplished by laterally manipulating the selector button. This makes possible displaying of selectable modes classified by group on the LCD panel in a way perceivable at a glance. Furthermore, the choice of a group and that of a mode within each group are matched in the mode display arrangement to facilitate the operation for mode selection.Type: ApplicationFiled: May 21, 2002Publication date: November 28, 2002Applicant: FUJI PHOTO OPTICAL CO., LTD.Inventors: Takao Umetsu, Haruo Onozuka, Minoru Ishiguro, Yasuhiro Nishitani, Kunihiko Tanaka, Makoto Akiba