Patents by Inventor Yasuhiro Nishitani

Yasuhiro Nishitani has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9334289
    Abstract: The present invention provides a novel compound which has a wide antimicrobial spectrum, and in particular exhibits potent antimicrobial activity against beta-lactamase producing Gram negative bacteria. Specifically, the present invention provides a compound of the formula (I): wherein each symbol is as defined in the specification, or an amino-protected compound when the amino group is present on the ring in the 7-side chain, or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition comprising the same.
    Type: Grant
    Filed: April 25, 2012
    Date of Patent: May 10, 2016
    Assignee: SHIONOGI & CO., LTD.
    Inventors: Yasuhiro Nishitani, Toshiaki Aoki, Jun Sato, Kenji Yamawaki, Katsuki Yokoo, Masayuki Sano
  • Patent number: 9242999
    Abstract: The present invention provides a novel compound which has a broad antibacterial spectrum and particularly exhibits a high antibacterial activity on ?-lactamase-producing gram-negative bacteria. Specifically provided are: a compound represented by formula (I) wherein the meaning of each symbol is as defined in the description, an amino-group-protected form of a type of the compound which has the amino group on a ring in a position-7 side chain, or a pharmaceutically acceptable salt of the compound or the amino-group-protected form; and a pharmaceutical composition containing the compound, the amino-group-protected form or the pharmaceutically acceptable salt.
    Type: Grant
    Filed: June 26, 2012
    Date of Patent: January 26, 2016
    Assignee: SHIONOGI & CO., LTD.
    Inventors: Yasuhiro Nishitani, Toshiaki Aoki
  • Patent number: 9238657
    Abstract: The present disclosure describes Cephem compounds of the formula: wherein, X is N, CH or C—Cl; T is S or the like; A and G are lower alkylene or the like; B is a single bond or the like; D is optionally present, and when present is, —NR7—, —CO—, —CO—NR7—, —NR7—CO—, —NR7—CO—NR7—, or the like; F is optionally present, and when present is or phenylene; R3 and R4 are —OR8; R5 and R6 each is independently hydrogen, halogen, nitrile, or —OR8; or an ester at the carboxyl at the 7-position side chain or at the 4-position, a compound protected at the amino on the ring in the 7-side chain, a pharmaceutically acceptable salt, or a solvate thereof, which have a wide antimicrobial spectrum and have potent antimicrobial activity against beta-lactamase producing Gram negative bacteria.
    Type: Grant
    Filed: October 27, 2009
    Date of Patent: January 19, 2016
    Assignee: SHIONOGI & CO., LTD.
    Inventors: Yasuhiro Nishitani, Kenji Yamawaki, Yusuke Takeoka, Hideki Sugimoto, Shinya Hisakawa, Toshiaki Aoki
  • Patent number: 8933012
    Abstract: The present invention provides a novel glycopeptide antibiotic derivative.
    Type: Grant
    Filed: May 25, 2007
    Date of Patent: January 13, 2015
    Assignee: Shionogi & Co., Ltd.
    Inventors: Yasuhiro Nishitani, Osamu Yoshida, Tsutomu Iwaki, Issei Kato
  • Publication number: 20140114060
    Abstract: The present invention provides a novel compound which has a broad antibacterial spectrum and particularly exhibits a high antibacterial activity on ?-lactamase-producing gram-negative bacteria. Specifically provided are: a compound represented by formula (I) wherein the meaning of each symbol is as defined in the description, an amino-group-protected form of a type of the compound which has the amino group on a ring in a position-7 side chain, or a pharmaceutically acceptable salt of the compound or the amino-group-protected form; and a pharmaceutical composition containing the compound, the amino-group-protected form or the pharmaceutically acceptable salt.
    Type: Application
    Filed: June 26, 2012
    Publication date: April 24, 2014
    Applicant: SHIONOGI & CO., LTD.
    Inventors: Yasuhiro Nishitani, Toshiaki Aoki
  • Publication number: 20140088302
    Abstract: The present invention provides a novel compound which has a wide antimicrobial spectrum, and in particular exhibits potent antimicrobial activity against beta-lactamase producing Gram negative bacteria. Specifically, the present invention provides a compound of the formula (I): wherein each symbol is as defined in the specification, or an amino-protected compound when the amino group is present on the ring in the 7-side chain, or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition comprising the same.
    Type: Application
    Filed: April 25, 2012
    Publication date: March 27, 2014
    Applicant: SHIONOGI & CO., LTD.
    Inventors: Yasuhiro Nishitani, Toshiaki Aoki, Jun Sato, Kenji Yamawaki, Katsuki Yokoo, Masayuki SANO
  • Publication number: 20110190254
    Abstract: The present invention provides Cephem compounds which have a wide antimicrobial spectrum and have potent antimicrobial activity against beta-lactamase producing Gram negative bacteria as follows: A compound of the formula: wherein, X is N, CH or C—Cl; T is S or the like; A and G are lower alkylene or the like; B is a single bond or the like; D is a single bond, —NR7—, —CO—, —CO—NR7—, —NR7—CO—, —NR7—CO—NR7—, or the like; E is optionally substituted lower alkylene; F is a single bond or optionally substituted phenylene; R3, R4, R5 and R6 each is independently hydrogen, halogene, nitrile, or the like; or an ester, a compound protected at the amino on the ring in the 7-side chain, a pharmaceutically acceptable salt, or a solvate thereof.
    Type: Application
    Filed: October 27, 2009
    Publication date: August 4, 2011
    Applicant: SHIONOGI & CO., LTD.
    Inventors: Yasuhiro Nishitani, Kenji Yamawaki, Yusuke Takeoka, Hideki Sugimoto, Shinya Hisakawa, Toshiaki Aoki
  • Patent number: 7696354
    Abstract: A compound of the formula: (wherein, T is S, SO or O; X is halogen, CN, carbamoyl optionally substituted with lower alkyl, lower alkyl, lower alkoxy, or lower alkylthio; A is substituted lower alkylene (wherein the substituent is optionally substituted mono lower alkyl, optionally substituted lower alkylidene, or optionally substituted lower alkylene); Z+ is an optionally substituted, a cation and an N atom-containing heterocyclic group), ester, amino-protected compound wherein the amino bonds to a thiazole ring at the 7-position, or pharmaceutically acceptable salt or solvate thereof.
    Type: Grant
    Filed: April 9, 2008
    Date of Patent: April 13, 2010
    Assignee: Shionogi & Co., Ltd.
    Inventors: Yasuhiro Nishitani, Yoshinori Yamano
  • Publication number: 20090286717
    Abstract: The present invention provides a novel glycopeptide antibiotic derivative.
    Type: Application
    Filed: May 25, 2007
    Publication date: November 19, 2009
    Inventors: Yasuhiro Nishitani, Osamu Yoshida, Tsutomu Iwaki, Issei Kato
  • Publication number: 20090131655
    Abstract: A compound of the formula: (wherein, T is S, SO or O; X is halogen, CN, carbamoyl optionally substituted with lower alkyl, lower alkyl, lower alkoxy, or lower alkylthio; A is substituted lower alkylene (wherein the substituent is optionally substituted mono lower alkyl, optionally substituted lower alkylidene, or optionally substituted lower alkylene) Z+ is an optionally substituted, a cation and an N atom-containing heterocyclic group), ester, amino-protected compound wherein the amino bonds to a thiazole ring at the 7-position, or pharmaceutically acceptable salt or solvate thereof.
    Type: Application
    Filed: April 9, 2008
    Publication date: May 21, 2009
    Inventors: Yasuhiro Nishitani, Yoshinori Yamano
  • Patent number: 7384928
    Abstract: A compound of the formula: (wherein, T is S, SO or O; X is halogen, CN, carbamoyl optionally substituted with lower alkyl, lower alkyl, lower alkoxy, or lower alkylthio; A is substituted lower alkylene (wherein the substituent is optionally substituted mono lower alkyl, optionally substituted lower alkylidene, or optionally substituted lower alkylene); Z+ is an optionally substituted, a cation and an N atom-containing heterocyclic group), ester, amino-protected compound wherein the amino bonds to a thiazole ring at the 7-position, or pharmaceutically acceptable salt or solvate thereof.
    Type: Grant
    Filed: March 18, 2003
    Date of Patent: June 10, 2008
    Assignee: Shionogi & Co., Ltd.
    Inventors: Yasuhiro Nishitani, Yoshinori Yamano
  • Publication number: 20070219191
    Abstract: A compound of Formula 1: (wherein A is optionally substituted lower alkylene (substituent: mono- or di-lower alkyl, lower alkylidene, or lower alkylene having two or more carbons); Z+ is either of the groups shown below: (wherein R1 and R2 are each independently hydrogen, optionally substituted amino lower alkyl, optionally substituted aminocycloalkyl, optionally substituted cyclic amino, or optionally substituted cyclic amino lower alkyl; R9 is hydrogen or lower alkyl, or R1 and R9 taken together with an adjacent N atom may form optionally substituted cyclic amino; R3 is hydrogen or amino; X is N or CR4 (R4 is hydrogen or optionally substituted lower alkyl)), a pharmaceutically acceptable salt or a solvate thereof.
    Type: Application
    Filed: March 3, 2005
    Publication date: September 20, 2007
    Inventors: Yasuhiro Nishitani, Tatsuro Yasukata, Kenji Yamawaki
  • Patent number: 7116355
    Abstract: Printing light beams from a printing head that is driven based on image data are used for recording a latent image in a predetermined exposure area on an instant film. The instant film is exposed through an exposure opening formed through a case of a film pack. The printing head projects the printing light beams linearly along a main scan direction while moving in a sub scan direction perpendicular to the main scan direction. An illumination range of the printing light beams is determined to be wider than the exposure area in the main and sub scan directions, in consideration of clearances between the case and the instant film. So the entire exposure area is exposed even where the instant film deviates inside the case. A light-shielding housing for covering up a moving range of the printing head in a light-tight fashion is formed integrally with a pack loading chamber for loading the film pack.
    Type: Grant
    Filed: April 12, 1999
    Date of Patent: October 3, 2006
    Assignee: Fuji Photo Film Co., Ltd.
    Inventors: Hiroshi Omura, Yasuhiro Nishitani, Ko Aosaki, Yoshio Sugano
  • Publication number: 20050179731
    Abstract: Printing light beams from a printing head that is driven based on image data are used for recording a latent image in a predetermined exposure area on an instant film. The instant film is exposed through an exposure opening formed through a case of a film pack. The printing head projects the printing light beams linearly along a main scan direction while moving in a sub scan direction perpendicular to the main scan direction. An illumination range of the printing light beams is determined to be wider than the exposure area in the main and sub scan directions, in consideration of clearances between the case and the instant film. So the entire exposure area is exposed even where the instant film deviates inside the case. A light-shielding housing for covering up a moving range of the printing head in a light-tight fashion is formed integrally with a pack loading chamber for loading the film pack.
    Type: Application
    Filed: April 12, 2005
    Publication date: August 18, 2005
    Applicant: FUJI PHOTO FILM CO., LTD.
    Inventors: Hiroshi Omura, Yasuhiro Nishitani, Ko Aosaki, Yoshio Sugano
  • Publication number: 20050153950
    Abstract: A compound of the formula: (wherein, T is S, SO or O; X is halogen, CN, carbamoyl optionally substituted with lower alkyl, lower alkyl, lower alkoxy, or lower alkylthio; A is substituted lower alkylene (wherein the substituent is optionally substituted mono lower alkyl, optionally substituted lower alkylidene, or optionally substituted lower alkylene); Z+ is an optionally substituted, a cation and an N atom-containing heterocyclic group), ester, amino-protected compound wherein the amino bonds to a thiazole ring at the 7-position, or pharmaceutically acceptable salt or solvate thereof.
    Type: Application
    Filed: March 18, 2003
    Publication date: July 14, 2005
    Applicant: SHIONOGI & CO., LTD.
    Inventors: Yasuhiro Nishitani, Yoshinori Yamano
  • Patent number: 6801718
    Abstract: Modes of a camera are classified into groups according to their type. On an LCD panel, the different groups are displayed on different rows, and modes to be selected out of each group are displayed in different columns. Group selection is accomplished by vertically manipulating a selector button, and mode selection out of each group is accomplished by laterally manipulating the selector button. This makes possible displaying of selectable modes classified by group on the LCD panel in a way perceivable at a glance. Furthermore, the choice of a group and that of a mode within each group are matched in the mode display arrangement to facilitate the operation for mode selection.
    Type: Grant
    Filed: May 21, 2002
    Date of Patent: October 5, 2004
    Assignees: Fuji Photo Optical Co., Ltd., Fuji Photo Film Co., Ltd.
    Inventors: Takao Umetsu, Haruo Onozuka, Minoru Ishiguro, Yasuhiro Nishitani, Kunihiko Tanaka, Makoto Akiba
  • Patent number: 6800621
    Abstract: A cefem compound of the formula (I) shows wide antibacterial spectrum against various pathogenic bacteria including MRSA. wherein, X is N or CY and Y is H or halogen; R1 is amino or protected amino; R2 is hydrogen or optionally substituted lower alkyl etc.; R3 is hydrogen etc.; R4 is hydrogen, optionally substituted lower alkyl, or optionally substituted N-containing heterocyclic group etc.; R5 is hydrogen etc.; and a wavy line means syn- or anti-isomerism or a mixture thereof.
    Type: Grant
    Filed: December 13, 2002
    Date of Patent: October 5, 2004
    Assignee: Shionogi & Co., Ltd.
    Inventors: Yasuhiro Nishitani, Hikaru Itani, Tadashi Irie
  • Publication number: 20030149014
    Abstract: A cefem compound of the formula (I) shows wide antibacterial spectrum against various pathogenic bacteria including MRSA.
    Type: Application
    Filed: December 13, 2002
    Publication date: August 7, 2003
    Applicant: Shionogi & Co., Ltd.
    Inventors: Yasuhiro Nishitani, Hikaru Itani, Tadashi Irie
  • Patent number: 6518263
    Abstract: A cefem compound of the formula (I) shows wide antibacterial spectrum against various pathogenic bacteria including MRSA. wherein, X is N or CY and Y is H or halogen; R1 is amino or protected amino; R2 is hydrogen or optionally substituted lower alkyl etc.; R3 is hydrogen etc.; R4 is hydrogen, optionally substituted lower alkyl, or optionally substituted N-containing heterocyclic group etc.; R5 is hydrogen etc.; and a wavy line means syn- or anti-isomerism or a mixture thereof.
    Type: Grant
    Filed: May 25, 2001
    Date of Patent: February 11, 2003
    Assignee: Shionogi & Co., Ltd.
    Inventors: Yasuhiro Nishitani, Hikaru Itani, Tadashi Irie
  • Publication number: 20020176709
    Abstract: Modes of a camera are classified into groups according to their type. On an LCD panel, the different groups are displayed on different rows, and modes to be selected out of each group are displayed in different columns. Group selection is accomplished by vertically manipulating a selector button, and mode selection out of each group is accomplished by laterally manipulating the selector button. This makes possible displaying of selectable modes classified by group on the LCD panel in a way perceivable at a glance. Furthermore, the choice of a group and that of a mode within each group are matched in the mode display arrangement to facilitate the operation for mode selection.
    Type: Application
    Filed: May 21, 2002
    Publication date: November 28, 2002
    Applicant: FUJI PHOTO OPTICAL CO., LTD.
    Inventors: Takao Umetsu, Haruo Onozuka, Minoru Ishiguro, Yasuhiro Nishitani, Kunihiko Tanaka, Makoto Akiba