Abstract: To be self-propelled in a simple configuration and to perform manual operation smoothly and briskly. A driving wheel includes: a base portion; a rotating shaft (first shaft) rotatably provided with respect to the base portion; a rotation member rotatably provided around the rotating shaft; a drive shaft (second shaft) provided on the rotation member orthogonally to the rotating shaft; a drive wheel provided on the rotation member and rotatable around the drive shaft; a drive unit provided on the rotation member and configured to rotationally drive the drive wheel; and a lock mechanism configured to permit rotation of the rotation member with respect to the base portion, and meanwhile, to deter the rotation of the rotation member with respect to the base portion.

Abstract: To be self-propelled in a simple configuration and to perform manual operation smoothly and briskly. A driving wheel includes: a base portion; a rotating shaft (first shaft) rotatably provided with respect to the base portion; a rotation member rotatably provided around the rotating shaft; a drive shaft (second shaft) provided on the rotation member orthogonally to the rotating shaft; a drive wheel provided on the rotation member and rotatable around the drive shaft; a drive unit provided on the rotation member and configured to rotationally drive the drive wheel; and a lock mechanism configured to permit rotation of the rotation member with respect to the base portion, and meanwhile, to deter the rotation of the rotation member with respect to the base portion.

Abstract: Peptide SY is produced by applying a mixture of peptides obtained by processing fish meat with a protease to a peptide-adsorbing resin (ODS resin or the like), eluting this with water, then with a 11 to 18% v/v ethanol aqueous solution and further with water, and collecting and mixing a latter fraction of the water elution (1), a fraction of the 11 to 18 % v/v ethanol elution and a fraction of the water elution (2). Further, peptide SY-MD is produced by isolating only the fraction of the 11 to 18% v/v ethanol elution. Peptide SY and peptide SY-MD are both novel peptide mixtures. They not only contain a large amount of blood pressure-depressing peptide Val-Tyr newly found but also have less bitterness and are excellent in taste and stability, and can be used as a blood pressure-depressing agent or as functional foods for inhibiting blood pressure elevation or preventing blood pressure elevation.

Abstract: Peptide SY is produced by applying a mixture of peptides obtained by processing fish meat with a protease to a peptide-adsorbing resin (ODS resin or the like), eluting this with water, then with a 11 to 18% v/v ethanol aqueous solution and further with water, and collecting and mixing a latter fraction of the water elution (1), a fraction of the 11 to 18 % v/v ethanol elution and a fraction of the water elution (2). Further, peptide SY-MD is produced by isolating only the fraction of the 11 to 18% v/v ethanol elution.