Patents by Inventor Yasunori Yonejima

Yasunori Yonejima has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210285020
    Abstract: The present invention provides production of hydroxylated fatty acid by a hydration reaction using a novel enzyme derived from Lactobacillus and using fatty acid as a substrate, and further, a production method of oxo fatty acid by an enzyme reaction or chemical oxidation reaction using the hydroxylated fatty acid as a substrate. In addition, a valuable novel rare fatty acid obtained by such production method is also provided.
    Type: Application
    Filed: June 2, 2021
    Publication date: September 16, 2021
    Applicants: Kyoto University, Noster, Inc.
    Inventors: Jun OGAWA, Shigenobu KISHINO, Teruo KAWADA, Nobuyuki TAKAHASHI, Tsuyoshi GOTO, Yasunori YONEJIMA
  • Publication number: 20210236448
    Abstract: The invention provides a metabolism improving agent containing a rare fatty acid such as hydroxylated fatty acid, oxo fatty acid and the like, and further, food, pharmaceutical product and the like containing the metabolism improving agent.
    Type: Application
    Filed: February 12, 2021
    Publication date: August 5, 2021
    Applicants: KYOTO UNIVERSITY, Noster Inc.
    Inventors: Jun OGAWA, Shigenobu KISHINO, Teruo KAWADA, Nobuyuki TAKAHASHI, Tsuyoshi GOTO, Yasunori YONEJIMA
  • Patent number: 11046980
    Abstract: The present invention provides production of hydroxylated fatty acid by a hydration reaction using a novel enzyme derived from Lactobacillus and using fatty acid as a substrate, and further, a production method of oxo fatty acid by an enzyme reaction or chemical oxidation reaction using the hydroxylated fatty acid as a substrate. In addition, a valuable novel rare fatty acid obtained by such production method is also provided.
    Type: Grant
    Filed: May 6, 2019
    Date of Patent: June 29, 2021
    Assignees: KYOTO UNIVERSITY, Noster, Inc.
    Inventors: Jun Ogawa, Shigenobu Kishino, Teruo Kawada, Nobuyuki Takahashi, Tsuyoshi Goto, Yasunori Yonejima
  • Patent number: 10975397
    Abstract: The present invention provides a production method of oxo fatty acid, as well as rare fatty acids such as conjugated fatty acid, hydroxylated fatty acid, partially saturated fatty acid and the like, which uses 4 kinds of enzymes (fatty acid-hydratase, hydroxylated fatty acid-dehydrogenase, oxo fatty acid-isomerase, oxo fatty acid-enone reductase) derived from Lactobacillus plantarum including lactic acid bacteria and the like. Furthermore, the present invention also provides a more efficient production method of oxo fatty acid and the like, which partly uses a chemical oxidation reaction in combination.
    Type: Grant
    Filed: March 29, 2019
    Date of Patent: April 13, 2021
    Assignees: KYOTO UNIVERSITY, Noster Inc.
    Inventors: Jun Ogawa, Shigenobu Kishino, Sakayu Shimizu, Yasunori Yonejima
  • Patent number: 10952983
    Abstract: The invention provides a metabolism improving agent containing a rare fatty acid such as hydroxylated fatty acid, oxo fatty acid and the like, and further, food, pharmaceutical product and the like containing the metabolism improving agent.
    Type: Grant
    Filed: December 11, 2019
    Date of Patent: March 23, 2021
    Assignees: KYOTO UNIVERSITY, NITTO PHARMACEUTICAL INDUSTRIES, LTD.
    Inventors: Jun Ogawa, Shigenobu Kishino, Teruo Kawada, Nobuyuki Takahashi, Tsuyoshi Goto, Yasunori Yonejima
  • Publication number: 20210069141
    Abstract: The present invention provides an anti-inflammatory agent containing a rare fatty acid such as hydroxylated fatty acid, oxo fatty acid and the like, and further, food, pharmaceutical product and the like containing the anti-inflammatory agent.
    Type: Application
    Filed: November 19, 2020
    Publication date: March 11, 2021
    Applicants: KYOTO UNIVERSITY, NITTO PHARMACEUTICAL INDUSTRIES, LTD.
    Inventors: Jun OGAWA, Shigenobu KISHINO, Teruo KAWADA, Nobuyuki TAKAHASHI, Tsuyoshi GOTO, Tatsuya SUGAWARA, Yasunori YONEJIMA
  • Publication number: 20200101036
    Abstract: The invention provides a metabolism improving agent containing a rare fatty acid such as hydroxylated fatty acid, oxo fatty acid and the like, and further, food, pharmaceutical product and the like containing the metabolism improving agent.
    Type: Application
    Filed: December 11, 2019
    Publication date: April 2, 2020
    Applicants: KYOTO UNIVERSITY, NITTO PHARMACEUTICAL INDUSTRIES, LTD.
    Inventors: Jun OGAWA, Shigenobu KISHINO, Teruo KAWADA, Nobuyuki TAKAHASHI, Tsuyoshi GOTO, Yasunori YONEJIMA
  • Patent number: 10548868
    Abstract: The present invention provides a metabolism improving agent containing a rare fatty acid such as hydroxylated fatty acid, oxo fatty acid and the like, and further, food, pharmaceutical product and the like containing the metabolism improving agent.
    Type: Grant
    Filed: January 23, 2015
    Date of Patent: February 4, 2020
    Assignees: KYOTO UNIVERSITY, NITTO PHARMACEUTICAL INDUSTRIES, LTD.
    Inventors: Jun Ogawa, Shigenobu Kishino, Teruo Kawada, Nobuyuki Takahashi, Tsuyoshi Goto, Yasunori Yonejima
  • Patent number: 10507222
    Abstract: The present invention provides a lactobacillus that improves hyperuricemia, fatty liver and a lifestyle-related disease, and a composition containing the lactobacillus.
    Type: Grant
    Filed: May 28, 2015
    Date of Patent: December 17, 2019
    Assignee: NITTO PHARMACEUTICAL INDUSTRIES, LTD.
    Inventors: Yasunori Yonejima, Keiko Hisa, Yoshie Uchibori
  • Publication number: 20190256876
    Abstract: The present invention provides production of hydroxylated fatty acid by a hydration reaction using a novel enzyme derived from lactobacillus and using fatty acid as a substrate, and further, a production method of oxo fatty acid by an enzyme reaction or chemical oxidation reaction using the hydroxylated fatty acid as a substrate. In addition, a valuable novel rare fatty acid obtained by such production method is also provided.
    Type: Application
    Filed: May 6, 2019
    Publication date: August 22, 2019
    Applicants: KYOTO UNIVERSITY, NITTO PHARMACEUTICAL INDUSTRIES, LTD.
    Inventors: Jun OGAWA, Shigenobu KISHINO, Teruo KAWADA, Nobuyuki TAKAHASHI, Tsuyoshi GOTO, Yasunori YONEJIMA
  • Publication number: 20190223464
    Abstract: The present invention provides lactic acid bacterium-containing chocolate containing a lactic acid bacterium in a living state, wherein the average particle size of the solid particles in the lactic acid bacterium-containing chocolate is larger than 1 ?m and less than 9 ?m, and a manufacturing method thereof.
    Type: Application
    Filed: August 10, 2017
    Publication date: July 25, 2019
    Applicants: NITTO PHARMACEUTICAL INDUSTRIES, LTD., LOTTE CO., LTD.
    Inventors: Hiroaki ASHITANI, Toshiyuki KOYAMA, Yoko USAMIKRANK, Yusuke KABUKI, Yasunori YONEJIMA, Keiko HISA
  • Publication number: 20190218579
    Abstract: The present invention provides a production method of oxo fatty acid, as well as rare fatty acids such as conjugated fatty acid, hydroxylated fatty acid, partially saturated fatty acid and the like, which uses 4 kinds of enzymes (fatty acid-hydratase, hydroxylated fatty acid-dehydrogenase, oxo fatty acid-isomerase, oxo fatty acid-enone reductase) derived from Lactobacillus plantarum including lactic acid bacteria and the like. Furthermore, the present invention also provides a more efficient production method of oxo fatty acid and the like, which partly uses a chemical oxidation reaction in combination.
    Type: Application
    Filed: March 29, 2019
    Publication date: July 18, 2019
    Applicants: KYOTO UNIVERSITY, NITTO PHARMACEUTICAL INDUSTRIES, LTD.
    Inventors: Jun OGAWA, Shigenobu KISHINO, Sakayu SHIMIZU, Yasunori YONEJIMA
  • Patent number: 10294501
    Abstract: The present invention provides a production method of oxo fatty acid, as well as rare fatty acids such as conjugated fatty acid, hydroxylated fatty acid, partially saturated fatty acid and the like, which uses 4 kinds of enzymes (fatty acid-hydratase, hydroxylated fatty acid-dehydrogenase, oxo fatty acid-isomerase, oxo fatty acid-enone reductase) derived from Lactobacillus plantarum including lactic acid bacteria and the like. Furthermore, the present invention also provides a more efficient production method of oxo fatty acid and the like, which partly uses a chemical oxidation reaction in combination.
    Type: Grant
    Filed: June 21, 2017
    Date of Patent: May 21, 2019
    Assignees: KYOTO UNIVERSITY, NITTO PHARMACEUTICAL INDUSTRIES, LTD.
    Inventors: Jun Ogawa, Shigenobu Kishino, Sakayu Shimizu, Yasunori Yonejima
  • Patent number: 10285966
    Abstract: The invention provides a HYA derivative having superior physiological functions intrinsic to HYA and permitting easy ingestion and easy handling, and use thereof. In particular, the invention relates to an alkyl ester of 10-hydroxy-cis-12-octadecenoic acid, or an optical isomer thereof, or ester of 10-hydroxy-cis-12-octadecenoic acid with dihydric alkanol or an optical isomer thereof, and a composition (edible fat or oil, food, medicament, cosmetic etc.) containing same.
    Type: Grant
    Filed: June 2, 2016
    Date of Patent: May 14, 2019
    Assignees: NITTO PHARMACEUTICAL INDUSTRIES, LTD., KYOTO UNIVERSITY
    Inventors: Yasunori Yonejima, Jun Ogawa, Shigenobu Kishino
  • Patent number: 10287234
    Abstract: The invention provides a HYA derivative having superior physiological functions intrinsic to HYA and permitting easy ingestion and easy handling, and use thereof. In particular, the invention relates to a triglyceride in which at least one fatty acid forming an ester bond with a hydroxy group of glycerol is 10-hydroxy-cis-12-octadecenoic acid, or an optical isomer thereof, and a composition (edible fat or oil, food, medicament, cosmetic etc.) containing same.
    Type: Grant
    Filed: June 2, 2016
    Date of Patent: May 14, 2019
    Assignees: NITTO PHARMACEUTICAL INDUSTRIES, LTD., KYOTO UNIVERSITY
    Inventors: Yasunori Yonejima, Jun Ogawa, Shigenobu Kishino
  • Publication number: 20180318248
    Abstract: The invention provides a HYA derivative having superior physiological functions intrinsic to HYA and permitting easy ingestion and easy handling, and use thereof. In particular, the invention relates to an alkyl ester of 10-hydroxy-cis-12-octadecenoic acid, or an optical isomer thereof, or ester of 10-hydroxy-cis-12-octadecenoic acid with dihydric alkanol or an optical isomer thereof, and a composition (edible fat or oil, food, medicament, cosmetic etc.) containing same.
    Type: Application
    Filed: June 2, 2016
    Publication date: November 8, 2018
    Applicants: NITTO PHARMACEUTICAL INDUSTRIES, LTD., KYOTO UNIVERSITY
    Inventors: Yasunori YONEJIMA, Jun OGAWA, Shigenobu KISHINO
  • Publication number: 20180206540
    Abstract: By adding a viable lactic acid bacterium to a fat or oil composition, the present invention has succeeded in producing a lactic acid bacterium-containing fat or oil composition that has a high viability of the lactic acid bacterium and an excellent resistance to acids. By adding lactic acid bacteria powder or a chocolate with a high lactic acid bacterium concentration to a chocolate dough after tempering and before molding, moreover, the present invention has succeeded in producing a lactic acid bacterium-containing chocolate including a viable lactic acid bacterium by a simple producing method. Thus, provided is a lactic acid bacterium-containing chocolate with high palatability that contains a viable lactic acid bacterium.
    Type: Application
    Filed: May 31, 2016
    Publication date: July 26, 2018
    Inventors: Hiroaki ASHITANI, Toshiyuki KOYAMA, Yoko USAMIKRANK, Tomokazu ISHIZUKA, Keiji TADOKORO, Yusuke KABUKI, Yasunori YONEJIMA, Keiko HISA
  • Publication number: 20180170854
    Abstract: The invention provides a HYA derivative having superior physiological functions intrinsic to HYA and permitting easy ingestion and easy handling, and use thereof. In particular, the invention relates to a triglyceride in which at least one fatty acid forming an ester bond with a hydroxy group of glycerol is 10-hydroxy-cis-12-octadecenoic acid, or an optical isomer thereof, and a composition (edible fat or oil, food, medicament, cosmetic etc.) containing same.
    Type: Application
    Filed: June 2, 2016
    Publication date: June 21, 2018
    Applicants: NITTO PHARMACEUTICAL INDUSTRIES, LTD., KYOTO UNIVERSITY
    Inventors: Yasunori YONEJIMA, Jun OGAWA, Shigenobu KISHINO
  • Publication number: 20170335355
    Abstract: The present invention provides a production method of oxo fatty acid, as well as rare fatty acids such as conjugated fatty acid, hydroxylated fatty acid, partially saturated fatty acid and the like, which uses 4 kinds of enzymes (fatty acid-hydratase, hydroxylated fatty acid-dehydrogenase, oxo fatty acid-isomerase, oxo fatty acid-enone reductase) derived from Lactobacillus plantarum including lactic acid bacteria and the like. Furthermore, the present invention also provides a more efficient production method of oxo fatty acid and the like, which partly uses a chemical oxidation reaction in combination.
    Type: Application
    Filed: June 21, 2017
    Publication date: November 23, 2017
    Applicants: KYOTO UNIVERSITY, NITTO PHARMACEUTICAL INDUSTRIES, LTD.
    Inventors: Jun OGAWA, Shigenobu KISHINO, Sakayu SHIMIZU, Yasunori YONEJIMA
  • Patent number: 9719115
    Abstract: The present invention provides a production method of oxo fatty acid, as well as rare fatty acids such as conjugated fatty acid, hydroxylated fatty acid, partially saturated fatty acid and the like, which uses 4 kinds of enzymes (fatty acid-hydratase, hydroxylated fatty acid-dehydrogenase, oxo fatty acid-isomerase, oxo fatty acid-enone reductase) derived from Lactobacillus plantarum including lactic acid bacteria and the like. Furthermore, the present invention also provides a more efficient production method of oxo fatty acid and the like, which partly uses a chemical oxidation reaction in combination.
    Type: Grant
    Filed: November 6, 2012
    Date of Patent: August 1, 2017
    Assignees: Kyoto University, Nitto Pharmaceutical Industries, Ltd.
    Inventors: Jun Ogawa, Shigenobu Kishino, Sakayu Shimizu, Yasunori Yonejima