Patents by Inventor Yasunori Yonejima
Yasunori Yonejima has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20210285020Abstract: The present invention provides production of hydroxylated fatty acid by a hydration reaction using a novel enzyme derived from Lactobacillus and using fatty acid as a substrate, and further, a production method of oxo fatty acid by an enzyme reaction or chemical oxidation reaction using the hydroxylated fatty acid as a substrate. In addition, a valuable novel rare fatty acid obtained by such production method is also provided.Type: ApplicationFiled: June 2, 2021Publication date: September 16, 2021Applicants: Kyoto University, Noster, Inc.Inventors: Jun OGAWA, Shigenobu KISHINO, Teruo KAWADA, Nobuyuki TAKAHASHI, Tsuyoshi GOTO, Yasunori YONEJIMA
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Publication number: 20210236448Abstract: The invention provides a metabolism improving agent containing a rare fatty acid such as hydroxylated fatty acid, oxo fatty acid and the like, and further, food, pharmaceutical product and the like containing the metabolism improving agent.Type: ApplicationFiled: February 12, 2021Publication date: August 5, 2021Applicants: KYOTO UNIVERSITY, Noster Inc.Inventors: Jun OGAWA, Shigenobu KISHINO, Teruo KAWADA, Nobuyuki TAKAHASHI, Tsuyoshi GOTO, Yasunori YONEJIMA
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Patent number: 11046980Abstract: The present invention provides production of hydroxylated fatty acid by a hydration reaction using a novel enzyme derived from Lactobacillus and using fatty acid as a substrate, and further, a production method of oxo fatty acid by an enzyme reaction or chemical oxidation reaction using the hydroxylated fatty acid as a substrate. In addition, a valuable novel rare fatty acid obtained by such production method is also provided.Type: GrantFiled: May 6, 2019Date of Patent: June 29, 2021Assignees: KYOTO UNIVERSITY, Noster, Inc.Inventors: Jun Ogawa, Shigenobu Kishino, Teruo Kawada, Nobuyuki Takahashi, Tsuyoshi Goto, Yasunori Yonejima
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Patent number: 10975397Abstract: The present invention provides a production method of oxo fatty acid, as well as rare fatty acids such as conjugated fatty acid, hydroxylated fatty acid, partially saturated fatty acid and the like, which uses 4 kinds of enzymes (fatty acid-hydratase, hydroxylated fatty acid-dehydrogenase, oxo fatty acid-isomerase, oxo fatty acid-enone reductase) derived from Lactobacillus plantarum including lactic acid bacteria and the like. Furthermore, the present invention also provides a more efficient production method of oxo fatty acid and the like, which partly uses a chemical oxidation reaction in combination.Type: GrantFiled: March 29, 2019Date of Patent: April 13, 2021Assignees: KYOTO UNIVERSITY, Noster Inc.Inventors: Jun Ogawa, Shigenobu Kishino, Sakayu Shimizu, Yasunori Yonejima
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Patent number: 10952983Abstract: The invention provides a metabolism improving agent containing a rare fatty acid such as hydroxylated fatty acid, oxo fatty acid and the like, and further, food, pharmaceutical product and the like containing the metabolism improving agent.Type: GrantFiled: December 11, 2019Date of Patent: March 23, 2021Assignees: KYOTO UNIVERSITY, NITTO PHARMACEUTICAL INDUSTRIES, LTD.Inventors: Jun Ogawa, Shigenobu Kishino, Teruo Kawada, Nobuyuki Takahashi, Tsuyoshi Goto, Yasunori Yonejima
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Publication number: 20210069141Abstract: The present invention provides an anti-inflammatory agent containing a rare fatty acid such as hydroxylated fatty acid, oxo fatty acid and the like, and further, food, pharmaceutical product and the like containing the anti-inflammatory agent.Type: ApplicationFiled: November 19, 2020Publication date: March 11, 2021Applicants: KYOTO UNIVERSITY, NITTO PHARMACEUTICAL INDUSTRIES, LTD.Inventors: Jun OGAWA, Shigenobu KISHINO, Teruo KAWADA, Nobuyuki TAKAHASHI, Tsuyoshi GOTO, Tatsuya SUGAWARA, Yasunori YONEJIMA
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Publication number: 20200101036Abstract: The invention provides a metabolism improving agent containing a rare fatty acid such as hydroxylated fatty acid, oxo fatty acid and the like, and further, food, pharmaceutical product and the like containing the metabolism improving agent.Type: ApplicationFiled: December 11, 2019Publication date: April 2, 2020Applicants: KYOTO UNIVERSITY, NITTO PHARMACEUTICAL INDUSTRIES, LTD.Inventors: Jun OGAWA, Shigenobu KISHINO, Teruo KAWADA, Nobuyuki TAKAHASHI, Tsuyoshi GOTO, Yasunori YONEJIMA
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Patent number: 10548868Abstract: The present invention provides a metabolism improving agent containing a rare fatty acid such as hydroxylated fatty acid, oxo fatty acid and the like, and further, food, pharmaceutical product and the like containing the metabolism improving agent.Type: GrantFiled: January 23, 2015Date of Patent: February 4, 2020Assignees: KYOTO UNIVERSITY, NITTO PHARMACEUTICAL INDUSTRIES, LTD.Inventors: Jun Ogawa, Shigenobu Kishino, Teruo Kawada, Nobuyuki Takahashi, Tsuyoshi Goto, Yasunori Yonejima
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Patent number: 10507222Abstract: The present invention provides a lactobacillus that improves hyperuricemia, fatty liver and a lifestyle-related disease, and a composition containing the lactobacillus.Type: GrantFiled: May 28, 2015Date of Patent: December 17, 2019Assignee: NITTO PHARMACEUTICAL INDUSTRIES, LTD.Inventors: Yasunori Yonejima, Keiko Hisa, Yoshie Uchibori
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Publication number: 20190256876Abstract: The present invention provides production of hydroxylated fatty acid by a hydration reaction using a novel enzyme derived from lactobacillus and using fatty acid as a substrate, and further, a production method of oxo fatty acid by an enzyme reaction or chemical oxidation reaction using the hydroxylated fatty acid as a substrate. In addition, a valuable novel rare fatty acid obtained by such production method is also provided.Type: ApplicationFiled: May 6, 2019Publication date: August 22, 2019Applicants: KYOTO UNIVERSITY, NITTO PHARMACEUTICAL INDUSTRIES, LTD.Inventors: Jun OGAWA, Shigenobu KISHINO, Teruo KAWADA, Nobuyuki TAKAHASHI, Tsuyoshi GOTO, Yasunori YONEJIMA
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Publication number: 20190223464Abstract: The present invention provides lactic acid bacterium-containing chocolate containing a lactic acid bacterium in a living state, wherein the average particle size of the solid particles in the lactic acid bacterium-containing chocolate is larger than 1 ?m and less than 9 ?m, and a manufacturing method thereof.Type: ApplicationFiled: August 10, 2017Publication date: July 25, 2019Applicants: NITTO PHARMACEUTICAL INDUSTRIES, LTD., LOTTE CO., LTD.Inventors: Hiroaki ASHITANI, Toshiyuki KOYAMA, Yoko USAMIKRANK, Yusuke KABUKI, Yasunori YONEJIMA, Keiko HISA
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Publication number: 20190218579Abstract: The present invention provides a production method of oxo fatty acid, as well as rare fatty acids such as conjugated fatty acid, hydroxylated fatty acid, partially saturated fatty acid and the like, which uses 4 kinds of enzymes (fatty acid-hydratase, hydroxylated fatty acid-dehydrogenase, oxo fatty acid-isomerase, oxo fatty acid-enone reductase) derived from Lactobacillus plantarum including lactic acid bacteria and the like. Furthermore, the present invention also provides a more efficient production method of oxo fatty acid and the like, which partly uses a chemical oxidation reaction in combination.Type: ApplicationFiled: March 29, 2019Publication date: July 18, 2019Applicants: KYOTO UNIVERSITY, NITTO PHARMACEUTICAL INDUSTRIES, LTD.Inventors: Jun OGAWA, Shigenobu KISHINO, Sakayu SHIMIZU, Yasunori YONEJIMA
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Patent number: 10294501Abstract: The present invention provides a production method of oxo fatty acid, as well as rare fatty acids such as conjugated fatty acid, hydroxylated fatty acid, partially saturated fatty acid and the like, which uses 4 kinds of enzymes (fatty acid-hydratase, hydroxylated fatty acid-dehydrogenase, oxo fatty acid-isomerase, oxo fatty acid-enone reductase) derived from Lactobacillus plantarum including lactic acid bacteria and the like. Furthermore, the present invention also provides a more efficient production method of oxo fatty acid and the like, which partly uses a chemical oxidation reaction in combination.Type: GrantFiled: June 21, 2017Date of Patent: May 21, 2019Assignees: KYOTO UNIVERSITY, NITTO PHARMACEUTICAL INDUSTRIES, LTD.Inventors: Jun Ogawa, Shigenobu Kishino, Sakayu Shimizu, Yasunori Yonejima
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Patent number: 10285966Abstract: The invention provides a HYA derivative having superior physiological functions intrinsic to HYA and permitting easy ingestion and easy handling, and use thereof. In particular, the invention relates to an alkyl ester of 10-hydroxy-cis-12-octadecenoic acid, or an optical isomer thereof, or ester of 10-hydroxy-cis-12-octadecenoic acid with dihydric alkanol or an optical isomer thereof, and a composition (edible fat or oil, food, medicament, cosmetic etc.) containing same.Type: GrantFiled: June 2, 2016Date of Patent: May 14, 2019Assignees: NITTO PHARMACEUTICAL INDUSTRIES, LTD., KYOTO UNIVERSITYInventors: Yasunori Yonejima, Jun Ogawa, Shigenobu Kishino
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Patent number: 10287234Abstract: The invention provides a HYA derivative having superior physiological functions intrinsic to HYA and permitting easy ingestion and easy handling, and use thereof. In particular, the invention relates to a triglyceride in which at least one fatty acid forming an ester bond with a hydroxy group of glycerol is 10-hydroxy-cis-12-octadecenoic acid, or an optical isomer thereof, and a composition (edible fat or oil, food, medicament, cosmetic etc.) containing same.Type: GrantFiled: June 2, 2016Date of Patent: May 14, 2019Assignees: NITTO PHARMACEUTICAL INDUSTRIES, LTD., KYOTO UNIVERSITYInventors: Yasunori Yonejima, Jun Ogawa, Shigenobu Kishino
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Publication number: 20180318248Abstract: The invention provides a HYA derivative having superior physiological functions intrinsic to HYA and permitting easy ingestion and easy handling, and use thereof. In particular, the invention relates to an alkyl ester of 10-hydroxy-cis-12-octadecenoic acid, or an optical isomer thereof, or ester of 10-hydroxy-cis-12-octadecenoic acid with dihydric alkanol or an optical isomer thereof, and a composition (edible fat or oil, food, medicament, cosmetic etc.) containing same.Type: ApplicationFiled: June 2, 2016Publication date: November 8, 2018Applicants: NITTO PHARMACEUTICAL INDUSTRIES, LTD., KYOTO UNIVERSITYInventors: Yasunori YONEJIMA, Jun OGAWA, Shigenobu KISHINO
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Publication number: 20180206540Abstract: By adding a viable lactic acid bacterium to a fat or oil composition, the present invention has succeeded in producing a lactic acid bacterium-containing fat or oil composition that has a high viability of the lactic acid bacterium and an excellent resistance to acids. By adding lactic acid bacteria powder or a chocolate with a high lactic acid bacterium concentration to a chocolate dough after tempering and before molding, moreover, the present invention has succeeded in producing a lactic acid bacterium-containing chocolate including a viable lactic acid bacterium by a simple producing method. Thus, provided is a lactic acid bacterium-containing chocolate with high palatability that contains a viable lactic acid bacterium.Type: ApplicationFiled: May 31, 2016Publication date: July 26, 2018Inventors: Hiroaki ASHITANI, Toshiyuki KOYAMA, Yoko USAMIKRANK, Tomokazu ISHIZUKA, Keiji TADOKORO, Yusuke KABUKI, Yasunori YONEJIMA, Keiko HISA
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Publication number: 20180170854Abstract: The invention provides a HYA derivative having superior physiological functions intrinsic to HYA and permitting easy ingestion and easy handling, and use thereof. In particular, the invention relates to a triglyceride in which at least one fatty acid forming an ester bond with a hydroxy group of glycerol is 10-hydroxy-cis-12-octadecenoic acid, or an optical isomer thereof, and a composition (edible fat or oil, food, medicament, cosmetic etc.) containing same.Type: ApplicationFiled: June 2, 2016Publication date: June 21, 2018Applicants: NITTO PHARMACEUTICAL INDUSTRIES, LTD., KYOTO UNIVERSITYInventors: Yasunori YONEJIMA, Jun OGAWA, Shigenobu KISHINO
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Publication number: 20170335355Abstract: The present invention provides a production method of oxo fatty acid, as well as rare fatty acids such as conjugated fatty acid, hydroxylated fatty acid, partially saturated fatty acid and the like, which uses 4 kinds of enzymes (fatty acid-hydratase, hydroxylated fatty acid-dehydrogenase, oxo fatty acid-isomerase, oxo fatty acid-enone reductase) derived from Lactobacillus plantarum including lactic acid bacteria and the like. Furthermore, the present invention also provides a more efficient production method of oxo fatty acid and the like, which partly uses a chemical oxidation reaction in combination.Type: ApplicationFiled: June 21, 2017Publication date: November 23, 2017Applicants: KYOTO UNIVERSITY, NITTO PHARMACEUTICAL INDUSTRIES, LTD.Inventors: Jun OGAWA, Shigenobu KISHINO, Sakayu SHIMIZU, Yasunori YONEJIMA
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Patent number: 9719115Abstract: The present invention provides a production method of oxo fatty acid, as well as rare fatty acids such as conjugated fatty acid, hydroxylated fatty acid, partially saturated fatty acid and the like, which uses 4 kinds of enzymes (fatty acid-hydratase, hydroxylated fatty acid-dehydrogenase, oxo fatty acid-isomerase, oxo fatty acid-enone reductase) derived from Lactobacillus plantarum including lactic acid bacteria and the like. Furthermore, the present invention also provides a more efficient production method of oxo fatty acid and the like, which partly uses a chemical oxidation reaction in combination.Type: GrantFiled: November 6, 2012Date of Patent: August 1, 2017Assignees: Kyoto University, Nitto Pharmaceutical Industries, Ltd.Inventors: Jun Ogawa, Shigenobu Kishino, Sakayu Shimizu, Yasunori Yonejima