Patents by Inventor Yasuo Kitani
Yasuo Kitani has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20170022220Abstract: An object of the present invention is to provide a high-purity crystal of a compound represented by formula (1a) that is an activated blood coagulation factor X (FXa) inhibitor. Solution: High-purity crystals of a compound represented by the following formula (1a): wherein, with regard to the content of impurities, the maximum content of any one type of impurity is 0.03% or less, and the total content of impurities is 0.13% or less, and wherein the high-purity crystals are obtained by a step of dissolving crystals in a solvent and then recrystallizing them.Type: ApplicationFiled: February 23, 2015Publication date: January 26, 2017Applicant: Daiichi Sankyo Company, LimitedInventors: Koutarou Kawanami, Yasuo Kitani
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Patent number: 8058440Abstract: 5-Methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylic acid of formula (5) or a salt thereof, is prepared by reacting reacting 2-bromo-5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine of formula (3) or a salt thereof, with a metal cyanide, to obtain 2-cyano-5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine of formula (4) or a salt thereof, and hydrolyzing the 2-cyano-5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine of formula (4) or a salt thereof.Type: GrantFiled: November 8, 2010Date of Patent: November 15, 2011Assignee: Daiichi Sankyo Company, LimitedInventors: Hiroshi Nagasawa, Koji Sato, Tsutomu Yagi, Yasuo Kitani
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Publication number: 20110054177Abstract: 5-Methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylic acid of formula (5) or a salt thereof, is prepared by reacting reacting 2-bromo-5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine of formula (3) or a salt thereof, with a metal cyanide, to obtain 2-cyano-5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine of formula (4) or a salt thereof, and hydrolyzing the 2-cyano-5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine of formula (4) or a salt thereof.Type: ApplicationFiled: November 8, 2010Publication date: March 3, 2011Applicant: DAIICHI PHARMACEUTICAL CO., LTD.Inventors: Hiroshi NAGASAWA, Koji Sato, Tsutomu Yagi, Yasuo Kitani
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Patent number: 7880005Abstract: 5-Methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine of formula (6) or a salt thereof, is prepared by reacting 2-amino-5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine of formula (2) or a salt thereof, with an alkali metal nitrite in the presence of a reducing agent in an aqueous solution of an acidic compound.Type: GrantFiled: December 4, 2009Date of Patent: February 1, 2011Assignee: Daiichi Sankyo Company, LimitedInventors: Hiroshi Nagasawa, Koji Sato, Tsutomu Yagi, Yasuo Kitani
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Publication number: 20100076192Abstract: 5-Methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine of formula (6) or a salt thereof, is prepared by reacting 2-amino-5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine of formula (2) or a salt thereof, with an alkali metal nitrite in the presence of a reducing agent in an aqueous solution of an acidic compound.Type: ApplicationFiled: December 4, 2009Publication date: March 25, 2010Applicant: DAIICHI PHARMACEUTICAL CO., LTD.Inventors: Hiroshi Nagasawa, Koji Sato, Tsutomu Yagi, Yasuo Kitani
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Patent number: 7678910Abstract: 5-Methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylic acid of formula (5) or a salt thereof, [F14] is prepared by reacting a compound of formula (6) or a salt thereof, with a trihalogenoacetyl halide in the presence of a base, followed by hydrolysis.Type: GrantFiled: April 6, 2009Date of Patent: March 16, 2010Assignee: Daiichi Sankyo Company, LimitedInventors: Hiroshi Nagasawa, Koji Sato, Tsutomu Yagi, Yasuo Kitani
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Publication number: 20090192313Abstract: 5-Methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylic acid of formula (5) or a salt thereof, [F14] is prepared by reacting a compound of formula (6) or a salt thereof, with a trihalogenoacetyl halide in the presence of a base, followed by hydrolysis.Type: ApplicationFiled: April 6, 2009Publication date: July 30, 2009Applicant: DAIICHI PHARMACEUTICAL CO., LTD.Inventors: Hiroshi NAGASAWA, Koji SATO, Tsutomu YAGI, Yasuo KITANI
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Patent number: 7547786Abstract: The present invention provides processes for producing a compound (5) based on the following reaction scheme.Type: GrantFiled: November 12, 2004Date of Patent: June 16, 2009Assignee: Daiichi Sankyo Company, LimitedInventors: Hiroshi Nagasawa, Koji Sato, Tsutomu Yagi, Yasuo Kitani
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Publication number: 20070166250Abstract: The present invention discloses a cosmetic polymer composition containing a straight-chain block copolymer, where the copolymer having a unit derived from a compound having an ethylenic unsaturated bond, having a number-average molecular weight of 1.0×103 to 1.0×106, and having at least two or more glass transition points or melting points; a hair cosmetic polymer composition containing a copolymer a copolymer capable of forming a film having a Young's modulus of 50 MPa or larger and a fracture-point elongation of 100% or larger, and dispersible into water and/or alcohol; and a cosmetic material containing these compositions.Type: ApplicationFiled: March 29, 2007Publication date: July 19, 2007Inventors: Tomoaki HIWATASHI, Minako SHIBATA, Osamu NISHIZAWA, Masato ONOE, Yasuo KITANI
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Publication number: 20070135476Abstract: The present invention provides processes for producing a compound (5) based on the following reaction scheme.Type: ApplicationFiled: November 12, 2004Publication date: June 14, 2007Applicant: Daiichi Pharmaceutical Co., Ltd.Inventors: Hiroshi Nagasawa, Koji Sato, Tsutomu Yagi, Yasuo Kitani
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Publication number: 20050249692Abstract: A polymer having a weight-average molecular weight of 5.0×103 to 1.0×107 and comprising a repeating unit represented by formula (I) below: wherein R1 denotes a hydrogen atom or a hydrocarbon group, R2 denotes a hydrogen atom or a methyl group, X denotes a bivalent connecting group, m denotes 0 or 1, and the guanidino group may form an acid-addition salt is disclosed.Type: ApplicationFiled: August 28, 2003Publication date: November 10, 2005Inventors: Tomoaki Hiwatashi, Shinsuke Oouchi, Yasuo Kitani
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Publication number: 20040223933Abstract: The present invention discloses a cosmetic polymer composition containing a straight-chain block copolymer, where the copolymer having a unit derived from a compound having an ethylenic unsaturated bond, having a number-average molecular weight of 1.0×103 to 1.0×106, and having at least two or more glass transition points or melting points; a hair cosmetic polymer composition containing a copolymer a copolymer capable of forming a film having a Young's modulus of 50 MPa or larger and a fracture-point elongation of 100% or larger, and dispersible into water and/or alcohol; and a cosmetic material containing these compositions.Type: ApplicationFiled: March 12, 2004Publication date: November 11, 2004Applicant: MITSUBISHI CHEMICAL CORPORATIONInventors: Tomoaki Hiwatashi, Minako Shibata, Osamu Nishizawa, Masato Onoe, Yasuo Kitani
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Patent number: 6586106Abstract: Described is a thermoplastic resin film having on a surface thereof a hydroxy-modified imine polymer containing repeating units represented by the following general formula (I) in an amount of 5 mol % or more based on the total of repeating units.Type: GrantFiled: August 6, 2001Date of Patent: July 1, 2003Assignee: Yupo CorporationInventors: Nobuhiro Shibuya, Kazuhisa Kitamura, Ayako Shibata, Yasuo Kitani, Kazuhide Hayama
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Publication number: 20020172655Abstract: A cosmetic-use polymer having a weight average molecular weight of 5.0·103-1.Type: ApplicationFiled: February 28, 2002Publication date: November 21, 2002Applicant: MITSUBISHI CHEMICAL CORPORATIONInventors: Tomoaki Hiwatashi, Shinsuke Oouchi, Yasuo Kitani
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Publication number: 20020054991Abstract: Described is a thermoplastic resin film having on a surface thereof a hydroxy-modified imine polymer containing repeating units represented by the following general formula (I) in an amount of 5 mol % or more based on the total of repeating units.Type: ApplicationFiled: August 6, 2001Publication date: May 9, 2002Applicant: YUPO CORPORATIONInventors: Nobuhiro Shibuya, Kazuhisa Kitamura, Ayako Shibata, Yasuo Kitani, Kazuhide Hayama
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Patent number: 6375932Abstract: A hair cosmetic composition having an excellent hair setting property, and which imparts to hair good flexibility and a good finish feeling. The hair cosmetic composition comprises (a) a water-soluble amine-oxide-containing polymer having a weight-average molecular weight of 10,000 to 500,000 and (b) a water-soluble polymer selected from the group consisting of nonionic, cationic, anionic and amphoteric polymers. The weight ratio of component (a) to component (b) falls within a range of from 1:10 to 10:1. Components (a) and (b) are incorporated in a total amount of from 0.1 to 10 wt. % based on the hair cosmetic composition.Type: GrantFiled: September 9, 1997Date of Patent: April 23, 2002Assignee: Mitsubishi Chemical CorporationInventors: Tomoaki Hiwatashi, Yasuo Kitani, Kanji Narazaki, Kayo Itou, Kazuhide Hayama
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Patent number: 6300411Abstract: The present invention discloses an aqueous resin composition containing (A) a copolymer of (a) a monomer having one or more aldehyde groups or ketone groups, and a radical polymerizable unsaturated bond, in a molecule, with (b) a monomer having a radical polymerizable unsaturated bond copolymerizable with the monomer (a); (B) a hydrazine compound of the following formula (1) where R1, R2, R3 and R4 independently represent a hydrogen atom, or a hydroxyl group, p denotes an integer of 0 to 3, and q denotes an integer of 2 to 8, provided that the relationships p+q≦8 and p<q are satisfied; and an aqueous medium. When the aqueous resin composition of the present invention is applied and then dried, a film excellent in film intactness, transparency, whitening after water immersion, and adhesion after water immersion can be formed.Type: GrantFiled: March 19, 1999Date of Patent: October 9, 2001Assignee: Mitsubishi Chemical CorporationInventors: Toshiya Seko, Kazuhide Hayama, Yasuo Kitani, Kazumasa Kinugasa
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Patent number: 6123933Abstract: A hair cosmetic composition comprising an amine-oxide-containing water-soluble resin having a weight-average molecular weight of 5,000 to 1,000,000. The hair cosmetic composition of the present invention has excellent setting force, conditioning effects and hair-washing property and being free from stickiness.Type: GrantFiled: July 17, 1996Date of Patent: September 26, 2000Assignee: Mitsubishi Chemical CorporationInventors: Kazuhide Hayama, Yasuo Kitani, Tomoaki Hiwatashi
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Patent number: 5543440Abstract: A process for producing a powdered carboxyl-containing polymer comprising mixing a solution of a water-insoluble polymer containing a carboxyl group per molecule in a hydrophilic organic solvent (e.g., ethanol) and an aqueous solution of a dispersant comprising a neutralized copolymer of a carboxyl-containing unsaturated monomer and a (meth)acrylic ester to precipitate the water-insoluble polymer. Fine polymer particles free from adhesion or agglomeration are obtained efficiently. Since any residual unreacted carboxyl-containing monomers are dissolved out in water as a precipitating solvent, the resulting powdered polymer has a reduced residual content of the unreacted monomers which may be poisonous and is therefore useful as a base resin of cosmetics or a coating resin for applications involving contact with the skin.Type: GrantFiled: January 26, 1995Date of Patent: August 6, 1996Assignee: Mitsubishi Chemical CorporationInventors: Kazuhide Hayama, Yukio Saitoh, Yasuo Kitani, Katsuhiko Yamada