Abstract: An intracardiac defibrillation catheter system equipped with a defibrillation catheter, a power source device and an electrocardiograph. The defibrillation catheter is equipped with a first DC electrode group and a second DC electrode group. The power source device is equipped with a DC power source unit, a catheter-connected connector, an electrocardiograph-connected connector, an arithmetic processing unit, which controls the DC power source unit and has an output circuit for outputting a direct current voltage from the DC power source unit, and a changeover unit, in which the catheter-connected connector is connected to a common contact. The electrocardiograph-connected connector is connected to a first contact, and the arithmetic processing unit is connected to a second contact. In the intracardiac defibrillation catheter system, electric energy necessary and sufficient for defibrillation can be surely supplied.

Abstract: An intracardiac defibrillation catheter system equipped with a defibrillation catheter, a power source device and an electrocardiograph. The defibrillation catheter is equipped with a first DC electrode group and a second DC electrode group. The power source device is equipped with a DC power source unit, a catheter-connected connector, an electrocardiograph-connected connector, an arithmetic processing unit, which controls the DC power source unit and has an output circuit for outputting a direct current voltage from the DC power source unit, and a changeover unit, in which the catheter-connected connector is connected to a common contact. The electrocardiograph-connected connector is connected to a first contact, and the arithmetic processing unit is connected to a second contact. In the intracardiac defibrillation catheter system, electric energy necessary and sufficient for defibrillation can be surely supplied.

Abstract: An intracardiac defibrillation catheter capable of supplying electric energy necessary and sufficient for defibrillation and conducting a defibrillation treatment without causing a burn on the body surface of a patient. The intracardiac defibrillation catheter is equipped with an insulated tube member having a multi-lumen structure, a handle connected to a proximal end of the tube member, a DC electrode group installed in a distal region of the tube member, a second DC electrode group installed on the tube member towards proximal direction from the first DC electrode group, a first lead wire group composed of lead wires connected to the respective electrodes making up the first DC electrode group, and a second lead wire group composed of lead wires connected to the respective electrodes making up the second DC electrode group, wherein the first lead wire group and the second lead wire group respectively extend into different lumens of the tube member.

Abstract: A radiofrequency electric current ablation catheter comprising a tip electrode, a means for detecting temperature of the tip electrode, a catheter shaft and a portion for operation at proximal end, wherein the tip electrode has a shape formed by connecting three or more spherical or approximately spherical surfaces having centers on the same straight line to each other with a curved surface. The catheter has the tip electrode which has a small diameter, is brought into excellent contact with organisms, can provide a great output power and is easily cooled with the circulating blood stream.

Abstract: A radiofrequency electric current ablation catheter comprising a tip electrode, a means for detecting temperature of the tip electrode, a catheter shaft and a portion for operation at proximal end, wherein the tip electrode has a shape formed by connecting three or more spherical or approximately spherical surfaces having centers on the same straight line to each other with a curved surface. The catheter has the tip electrode which has a small diameter, is brought into excellent contact with organisms, can provide a great output power and is easily cooled with the circulating blood stream.

Abstract: A pharmaceutical composition for treating viral diseases, such as pasta, gargle, gel, ointment, suppository, spray, etc., containing interferon in a stable state which comprises an effective amount of human interferon, 15 to 60% by weight of a tri or higher polyhydric sugar alcohol and an organic acid buffer as stabilizers, and a conventional pharmaceutical carrier or diluent. The pH of the composition is about 3 to 6. Optionally, the composition can further contain as a stabilizer an anionic surfactant and/or albumin.

Abstract: A pharmaceutical composition for treating erythematodes, particularly, lupus erythematodes discoides, or mycosis, particularly, candidasis, by topical or local administration which comprises an effective amount of human interferon, a trihydric or more higher polyhydric sugar alcohol, an organic acid buffer and, optionally, an anionic surfactant and albumin, and a conventional pharmaceutical carrier or diluent. A method for treating a human subject suffering from erythematodes and mycosis by using this composition is also provided.

Abstract: A pharmaceutical composition for treating keratosic disorders of skin and mucosa, particularly, lichen planus and leukoplakia, by topical or local administration which comprises an effective amount of human interferon, a trihydric or more higher polyhydric sugar alcohol, an organic acid buffer and, optionally, an anionic surfactant and albumin, and a conventional pharmaceutical carrier or diluent. A method for treating a human subject suffering from keratosic disorders of skin and mucosa by using this composition is also provided.