Abstract: The present invention provides a pharmaceutical composition for use as an NPY Y5 receptor antagonist comprising a compound of the formula (I): wherein R1 is lower alkyl, cycloalkyl or the like, R2 is hydrogen, lower alkyl or the like, n is 1 or 2, X is lower alkylene, lower alkenylene, arylene, cycloalkylene or the like, Y is CONR7, CSNR7, NR7CO, NR7CS or the like, Z is lower alkyl, optionally substituted carbocyclyl, optionally substituted heterocyclyl or the like and R7 is hydrogen or lower alkyl, prodrug, pharmaceutically acceptable salt or solvate thereof.

Abstract: The present invention provides a pharmaceutical composition for use as an NPY Y5 receptor antagonist comprising a compound of the formula (I): wherein R1 is lower alkyl, cycloalkyl or the like, R2 is hydrogen, lower alkyl or the like, n is 1 or 2, X is lower alkylene, lower alkenylene, arylene, cycloalkylene or the like, Y is CONR7, CSNR7, NR7CO, NR7CS or the like, Z is lower alkyl, optionally substituted carbocyclyl, optionally substituted heterocyclyl or the like and R7 is hydrogen or lower alkyl, prodrug, pharmaceutically acceptable salt or solvate thereof

Abstract: A process for the preparation of Compound (I) comprising reacting Compound (II) with a base in an aprotic solvent, which is represented by the following scheme: wherein R1 and R2 are each independently lower alkyl.

Abstract: A recording time setting process, performed by a data recording and reproduction apparatus capable of readily setting a recording start time and a recording finish time, includes: the step of detecting execution of a meter recording setting mode, the step of detecting an input of recording start position, the step of calculating a time from the recording start position, the step of storing the recording start time in a memory, the step of detecting an input of recording finish position, the step of calculating a time from the recording finish position, the step of calculating a recording time period when the recording finish position is determined, and the step of storing the recording finish time in the memory if the recording time period has not yet been selected for another recording and if the required capacity does not exceed the storage capacity of the HDD.

Abstract: A laser-diode drive circuit is provided with a filter circuit for noise elimination. A measure is taken to eliminate a fear that a leading edge of a signal waveform is so impaired due to a time constant of the filter circuit that a receiving side of optical communications may not be able to accurately detect a level 0 or 1 of the signal at rise time. For this purpose, a laser-diode drive circuit of the invention includes a control-signal generating circuit for generating a control signal over a predetermined time period immediately after the rise of an input signal waveform or an output current signal waveform, and a time-constant reduction circuit active to reduce the time constant of the filter circuit during the receipt of the control signal.

Abstract: The present invention provides a pharmaceutical composition for use as an NPY Y5 receptor antagonist comprising a compound of the formula (I): 1

Abstract: The present invention provides a pharmaceutical composition for use as an NPY Y5 receptor antagonist comprising a compound of the formula (I): 1

Abstract: An optical linkage device includes a trimmable resistance for controlling output characteristics of a laser diode; a board having the trimmable resistance mounted thereon; and a case at least covering the board, the case provided with an adjustment hole for adjustment of a resistance value of the trimmable resistance. This arrangement permits the adjustment of the output of the laser diode to be performed with the case fixed to place. Thus is provided the optical linkage device capable of maintaining a more stable product quality.

Abstract: The present invention provides a pharmaceutical composition for use as an NPY Y5 receptor antagonist comprising a compound of the formula (I): wherein R1 is lower alkyl, cycloalkyl or the like, R2 is hydrogen, lower alkyl or the like, n is 1 or 2, X is lower alkylene, lower alkenylene, arylene, cycloalkylene or the like, Y is CONR7, CSNR7, NR7CO, NR7CS or the like, Z is lower alkyl, optionally substituted carbocyclyl, optionally substituted heterocyclyl or the like and R7 is hydrogen or lower alkyl, prodrug, pharmaceutically acceptable salt or solvate thereof.

Abstract: An optical linkage device includes a trimmable resistance for controlling output characteristics of a laser diode; a board having the trimmable resistance mounted thereon; and a case at least covering the board, the case provided with an adjustment hole for adjustment of a resistance value of the trimmable resistance. This arrangement permits the adjustment of the output of the laser diode to be performed with the case fixed to place. Thus is provided the optical linkage device capable of maintaining a more stable product quality.