Abstract: Provided is a use of Wee1 kinase inhibitors in the treatment of cancer. In particular, provided is a use of Wee1 kinase inhibitors in the preparation of drugs for the treatment of cancers with Histone H3K27M mutation.

Abstract: A metalens configured to shape the focus light into a flexibly designed pattern. The present teachings demonstrate the engineering of metalens with artificial focus pattern by creating line and ring-shaped focus as ‘drawing tools’. These metalens are fabricated through a single layer of silicon-based material through CMOS compatible nano fabrication process. The mechanism to generate artificial focus pattern can be applied to a plethora of future on-chip optical devices with applications ranging from beam engineering to next generation nano lithography.

Abstract: A processing unit can train a model as a joint multi-domain recurrent neural network (JRNN), such as a bi-directional recurrent neural network (bRNN) and/or a recurrent neural network with long-short term memory (RNN-LSTM) for spoken language understanding (SLU). The processing unit can use the trained model to, e.g., jointly model slot filling, intent determination, and domain classification. The joint multi-domain model described herein can estimate a complete semantic frame per query, and the joint multi-domain model enables multi-task deep learning leveraging the data from multiple domains. The joint multi-domain recurrent neural (JRNN) can leverage semantic intents (such as, finding or identifying, e.g., a domain specific goal) and slots (such as, dates, times, locations, subjects, etc.) across multiple domains.

Abstract: A processing unit can train a model as a joint multi-domain recurrent neural network (JRNN), such as a bi-directional recurrent neural network (bRNN) and/or a recurrent neural network with long-short term memory (RNN-LSTM) for spoken language understanding (SLU). The processing unit can use the trained model to, e.g., jointly model slot filling, intent determination, and domain classification. The joint multi-domain model described herein can estimate a complete semantic frame per query, and the joint multi-domain model enables multi-task deep learning leveraging the data from multiple domains. The joint multi-domain recurrent neural network (JRNN) can leverage semantic intents (such as, finding or identifying, e.g., a domain specific goal) and slots (such as, dates, times, locations, subjects, etc.) across multiple domains.

Abstract: The present disclosure relates to an electronic device, a method, and a computer-readable medium for quickly switching channels. An electronic device is provided. The electronic device includes: a memory having instructions stored thereon; and a processor. The processor is configured to execute the instructions stored on the memory to cause the electronic device to execute the following operations: playing a first program of a first channel, wherein the first program is a live program; receiving user input when playing the first program; and in response to receiving the user input, switching from the first channel to a second channel and playing a second program of the second channel, wherein the second program is an OTT program.

Abstract: The present application describes a system and method for searching for content items in an application executing on a computing device. In order to increase the efficiency of the search, the present disclosure provides a refiner that is used to filter or otherwise refine search results. The refiner is user-specific and/or tenant/entity-specific. The refiner may be based on long-term aggregated data and/or contextual information associated with the user.

Abstract: The present disclosure relates to an electronic device and its execution method and a computer-readable medium. An electronic device, comprising: a memory, in which instructions are stored; and a processor, configured to execute the instructions stored in the memory to cause the electronic device to execute the following operations: receiving a request for entering a sleep mode; obtaining expected time to fall asleep; obtaining current volume value and/or current brightness value of a playback device; selecting a decay type; and determining a required amount of change per unit time of the brightness value and/or volume value of the playback device according to the decay type, expected time to fall asleep, and the current volume value and/or current brightness value.

Abstract: Automatically detected and identified tasks and calendar items from electronic communications may be populated into one or more tasks applications and calendaring applications. Text content retrieved from one or more electronic communications may be extracted and parsed for determining whether keywords or terms contained in the parsed text may lead to a classification of the text content or part of the text content as a task. Identified tasks may be automatically populated into a tasks application. Similarly, text content from such sources may be parsed for keywords and terms that may be identified as indicating calendar items, for example, meeting requests. Identified calendar items may be automatically populated into a calendar application as a calendar entry.

Abstract: Systems and methods are disclosed to provide optimized scheduling of calendar events based on flexibility scores of calendar events. A flexibility score may be representative of a probability or likelihood that a calendar event can or will be rescheduled in response to a conflicting calendar event. Flexibility scores of calendar events may be calculated based on one or more factors, which may be weighted, using one or more machine-learning models. Factors may include: event densities of invitees' calendars, organizational rankings of respective invitees, the remaining time before an event start time, an urgency of respective calendar events, etc. In this way, if open time slots are not available for all invitees to a proposed calendar request, an event organizer may identify time slots occupied by existing calendar events with the highest likelihood of being rescheduled in view of the proposed calendar event, thereby facilitating scheduling of the proposed calendar event.

Abstract: A computer-implemented technique is described herein for creating a relational data structure by extracting user data items from a collection of one or more applications sources. These data items evince interests exhibited by the users, and may include messages, documents, tasks, meetings, etc. The technique also collects knowledge data items from one or more knowledge sources. In one implementation, these data items may include terms used to describe skills possessed by the users. The technique constructs the data structure by providing objects associated with respective data items, and links between respective pairs of objects. In its real-time phase of operation, the technique allows a user to interrogate the relational data structure, e.g., to identify skills possessed by a particular user, to find users associated with a specified skill, etc.

Abstract: Automatically detected and identified tasks and calendar items from electronic communications may be populated into one or more tasks applications and calendaring applications. Text content retrieved from one or more electronic communications may be extracted and parsed for determining whether keywords or terms contained in the parsed text may lead to a classification of the text content or part of the text content as a task. Identified tasks may be automatically populated into a tasks application. Similarly, text content from such sources may be parsed for keywords and terms that may be identified as indicating calendar items, for example, meeting requests. Identified calendar items may be automatically populated into a calendar application as a calendar entry.

Abstract: Automatically detected and identified tasks and calendar items from electronic communications may be populated into one or more tasks applications and calendaring applications. Text content retrieved from one or more electronic communications may be extracted and parsed for determining whether keywords or terms contained in the parsed text may lead to a classification of the text content or part of the text content as a task. Identified tasks may be automatically populated into a tasks application. Similarly, text content from such sources may be parsed for keywords and terms that may be identified as indicating calendar items, for example, meeting requests. Identified calendar items may be automatically populated into a calendar application as a calendar entry.

Abstract: A computer-implemented technique is described herein for creating a relational data structure by extracting user data items from a collection of one or more applications sources. These data items evince interests exhibited by the users, and may include messages, documents, tasks, meetings, etc. The technique also collects knowledge data items from one or more knowledge sources. In one implementation, these data items may include terms used to describe skills possessed by the users. The technique constructs the data structure by providing objects associated with respective data items, and links between respective pairs of objects. In its real-time phase of operation, the technique allows a user to interrogate the relational data structure, e.g., to identify skills possessed by a particular user, to find users associated with a specified skill, etc.

Abstract: Intent determination as a service (IaaS) is disclosed. A third party application may be provided access to an IaaS service. The third party application and the IaaS system may exchange or be provided registration data and information that allow configuration of data and interfaces used in provision of IaaS to the third party application. A query received as input at the third party application may be sent to the IaaS system and the intent of a query may be determined and indicated in a query response sent back to the third party application. A third party application may also interface with a device client application integrated into the operating system of a device as part of accessing an IaaS system. Use of IaaS for queries associated with or relevant to third party applications may extend the capabilities of the third party applications and device client applications.

Abstract: The present disclosure relates to a field of optical module technology, and in particular to a monitoring indication system of an optical module. The monitoring indication system of the optical module includes a optical module and a monitoring indication system. The optical module includes a housing, a circuit board arranged in the housing, and an unlocking pull handle arranged on a rear end of the housing. The monitoring indication system includes a monitoring unit arranged on the circuit board, an indicator light connected with the monitoring unit, and a display portion arranged on the unlocking pull handle. The display portion is communicated with the indicator light. The monitoring unit obtains a working state or an abnormal state of the optical module, and generates a corresponding indication signal. The indicator light performs a corresponding light-emitting operation according to the indication signal, and transmits outwards from the display portion.

Abstract: Systems and methods are disclosed to provide optimized scheduling of calendar events based on flexibility scores of calendar events. A flexibility score may be representative of a probability or likelihood that a calendar event can or will be rescheduled in response to a conflicting calendar event. Flexibility scores of calendar events may be calculated based on one or more factors, which may be weighted, using one or more machine-learning models. Factors may include: event densities of invitees' calendars, organizational rankings of respective invitees, the remaining time before an event start time, an urgency of respective calendar events, etc. In this way, if open time slots are not available for all invitees to a proposed calendar request, an event organizer may identify time slots occupied by existing calendar events with the highest likelihood of being rescheduled in view of the proposed calendar event, thereby facilitating scheduling of the proposed calendar event.

Abstract: Techniques for providing a people recommendation system for predicting and recommending relevant people (or other entities) to include in a conversation based on contextual indicators. In an exemplary embodiment, email recipient recommendations may be suggested based on contextual signals, e.g., project names, body text, existing recipients, current date and time, etc. In an aspect, a plurality of properties including ranked key phrases are associated with profiles corresponding to personal entities. Aggregated profiles are analyzed using first- and second-layer processing techniques. The recommendations may be provided to the user reactively, e.g., in response to a specific query by the user to the people recommendation system, or proactively, e.g., based on the context of what the user is currently working on, in the absence of a specific query by the user.

Abstract: Structured web pages are accessed and parsed to obtain implicit annotation for natural language understanding tasks. Search queries that hit these structured web pages are automatically mined for information that is used to semantically annotate the queries. The automatically annotated queries may be used for automatically building statistical unsupervised slot filling models without using a semantic annotation guideline. For example, tags that are located on a structured web page that are associated with the search query may be used to annotate the query. The mined search queries may be filtered to create a set of queries that is in a form of a natural language query and/or remove queries that are difficult to parse. A natural language model may be trained using the resulting mined queries. Some queries may be set aside for testing and the model may be adapted using in-domain sentences that are not annotated.

Abstract: A system may comprise one or more processors and memory storing instructions that, when executed by one or more processors, configure one or more processors to perform a number of operations or tasks, such as receiving a query or a document, and mapping the query or the document into a lower dimensional representation by performing at least one operational layer that shares at least two disparate tasks.

Abstract: Techniques for providing a people recommendation system for predicting and recommending relevant people (or other entities) to include in a conversation. In an exemplary embodiment, a plurality of conversation boxes associated with communications between a user and target recipients, or between other users and recipients, are collected and stored as user history. During a training phase, the user history is used to train encoder and decoder blocks in a de-noising auto-encoder model. During a prediction phase, the trained encoder and decoder are used to predict one or more recipients for a current conversation box composed by the user, based on contextual and other signals extracted from the current conversation box. The predicted recipients are ranked using a scoring function, and the top-ranked individuals or entities may be recommended to the user.