Abstract: A microneedle structure, a manufacturing method therefor, and a manufacturing apparatus therefor are presented. The microneedle structure manufacturing method according to one embodiment of the present invention comprises the steps of: a) injecting, into a lower mold comprising a microneedle intaglio, a polymer solution containing a biocompatible polymer; and b) coupling a shape control mold, which comprises a protrusion, to the lower mold such that one end of the protrusion of the shape control mold is impregnated with the biocompatible polymer solution injected into the microneedle intaglio.

Abstract: The microfluidic device capable of initiating sequential flow according to the present invention includes: a main flow path in which a suction port for sucking the fluid with a negative pressure is formed at one end; a plurality of reservoirs that supply a fluid stored therein to the main flow path through an outlet by the negative pressure applied to the suction port, and are connected to a plurality of different points of the main flow path; and a blocking element that blocks the inflow of external air to the main flow path through the outlet when all the fluid in the reservoir flows out, wherein the fluid stored in a plurality of the reservoirs may flow sequentially.

Abstract: The present invention relates to a filter device for capturing a target cell and a target cell collecting method using the same. A filter substrate by which a target cell is captured is formed of an elastic material. When blood passes, the size of a lattice hole of the filter substrate by which the target cell is captured is reduced. When the blood completely passes, the size of the lattice hole of the filter substrate by which the target cell is captured is restored, so that a destruction rate of the target cell may be reduced and a collect rate of the target cell may be increased.

Abstract: In an apparatus for manufacturing a micro-channel and a method for manufacturing a micro-channel, the apparatus includes a base member and a holding chamber. The base member includes a first base member having a concave portion and a convex portion, and a second base member covering the concave portion to form a channel. The holding chamber holds the base member thereinside, to form a space uniformly applying a pressure on a surface of the base member. Accordingly, the pressure is uniformly applied on an entire surface of the base member and thus the micro-channel may be manufactured.

Abstract: A microneedle structure, a manufacturing method therefor, and a manufacturing apparatus therefor are presented. The microneedle structure manufacturing method according to one embodiment of the present invention comprises the steps of: a) injecting, into a lower mold comprising a microneedle intaglio, a polymer solution containing a biocompatible polymer; and b) coupling a shape control mold, which comprises a protrusion, to the lower mold such that one end of the protrusion of the shape control mold is impregnated with the biocompatible polymer solution injected into the microneedle intaglio.

Abstract: A hybrid type filtration structure for filtering liquid includes a first active layer, a porous supporting layer and a permeable layer. The first active layer has a first nano pore inner wall of which a function group included compound is combined with. The porous supporting layer has a plurality of pores and is disposed under the first active layer. The permeable layer is disposed under the porous supporting layer. The porous supporting layer includes a plurality of lipid bilayers having membrane protein inside of the pore, a molecule of water selectively passes through the membrane protein. The first nano pore passes through the first active layer vertically. The first nano pore and the pore are connected with each other through which liquid flows.

Abstract: The present invention relates to a filter device for capturing a target cell and a target cell collecting method using the same. A filter substrate by which a target cell is captured is formed of an elastic material. When blood passes, the size of a lattice hole of the filter substrate by which the target cell is captured is reduced. When the blood completely passes, the size of the lattice hole of the filter substrate by which the target cell is captured is restored, so that a destruction rate of the target cell may be reduced and a collect rate of the target cell may be increased.

Abstract: The present disclosure relates to a liquid filtration structure with one or more macromolecule membrane structures including membrane proteins selectively permeable to water molecules and fixed within a pore. A liquid filtration structure according to an exemplary embodiment of the present disclosure increases stability and durability of macromolecule membrane structures including membrane proteins selectively permeable to water molecules, and, thus, can be effectively used in a filtration device for purifying water.

Abstract: A hybrid type filtration structure for filtering liquid includes a first active layer, a porous supporting layer and a permeable layer. The first active layer has a first nano pore inner wall of which a function group included compound is combined with. The porous supporting layer has a plurality of pores and is disposed under the first active layer. The permeable layer is disposed under the porous supporting layer. The porous supporting layer includes a plurality of lipid bilayers having membrane protein inside of the pore, a molecule of water selectively passes through the membrane protein. The first nano pore passes through the first active layer vertically. The first nano pore and the pore are connected with each other through which liquid flows.

Abstract: The present disclosure relates to a liquid filtration structure with one or more macromolecule membrane structures including membrane proteins selectively permeable to water molecules and fixed within a pore. A liquid filtration structure according to an exemplary embodiment of the present disclosure increases stability and durability of macromolecule membrane structures including membrane proteins selectively permeable to water molecules, and, thus, can be effectively used in a filtration device for purifying water.

Abstract: In an apparatus for manufacturing a micro-channel and a method for manufacturing a micro-channel, the apparatus includes a base member and a holding chamber. The base member includes a first base member having a concave portion and a convex portion, and a second base member covering the concave portion to form a channel. The holding chamber holds the base member thereinside, to form a space uniformly applying a pressure on a surface of the base member. Accordingly, the pressure is uniformly applied on an entire surface of the base member and thus the micro-channel may be manufactured.

Abstract: A liquid filtering structure having high filtering efficiency, excellent transparency, and excellent durability can be provided. The liquid filtering structure includes a filtering layer, wherein the filtering layer includes a nanopore structure unit including a plurality of nanopores and a functional group-containing compound including functional groups at one end, and has selectivity with respect to liquid molecules to be filtered, for example, water molecules, and effectively filter liquid, particularly water by preventing ions or compounds from being passed.

Abstract: A method of manufacturing a roll for roll printing/roll imprinting is provided. The method includes preparing an exterior on one surface of which a printed pattern of a predetermined shape is formed and that has magnetic power and having the other surface of the exterior contact an external surface of a central roll so that the exterior is attached to the central roll having magnetic power by magnetic power. Therefore, the method of manufacturing a roll for roll printing/roll imprinting capable of reducing production cost to massively manufacture the roll for roll printing/roll imprinting is provided.

Abstract: Disclosed is an apparatus for self-extracting a cell using a magnetic field. The apparatus for self-extracting the cell using the magnetic field according to the present invention includes a flow path casing including an upper substrate and a lower substrate having a magnetic property combined with each other, and a fluid path formed to fluidize a cell solution therein; a separation portion disposed on the fluid path and provided with a separation channel selectively passing only an effective cell that is a separation target in the cell included in the cell solution therethrough; and a magnetic field control portion forming the magnetic field in the flow path portion to separate the cell blocking the separation channel from the separation channel.

Abstract: An apparatus for separating cells using magnetic force includes: a separation channel portion including ferromagnetic particles, and provided with a flow path through which a cell fluid containing a plurality of cells having at least one of diamagnetic and paramagnetic properties; and a magnetic field controller that generates a magnetic field within the flow path so that the cells in the cell fluid flow within the flow path and are separated by height by a magnetic field. Accordingly, there are provided an apparatus for separating cells using magnetic force and a cell separation method using the same, by which cells can be easily separated using magnetic force.

Abstract: Disclosed is an apparatus for self-extracting a cell using a magnetic field. The apparatus for self-extracting the cell using the magnetic field according to the present invention includes a flow path casing including an upper substrate and a lower substrate having a magnetic property combined with each other, and a fluid path formed to fluidize a cell solution therein; a separation portion disposed on the fluid path and provided with a separation channel selectively passing only an effective cell that is a separation target in the cell included in the cell solution therethrough; and a magnetic field control portion forming the magnetic field in the flow path portion to separate the cell blocking the separation channel from the separation channel.

Abstract: An apparatus for separating cells using magnetic force includes: a separation channel portion including ferromagnetic particles, and provided with a flow path through which a cell fluid containing a plurality of cells having at least one of diamagnetic and paramagnetic properties; and a magnetic field controller that generates a magnetic field within the flow path so that the cells in the cell fluid flow within the flow path and are separated by height by a magnetic field. Accordingly, there are provided an apparatus for separating cells using magnetic force and a cell separation method using the same, by which cells can be easily separated using magnetic force.

Abstract: A method of manufacturing a roll for roll printing/roll imprinting is provided. The method includes preparing an exterior on one surface of which a printed pattern of a predetermined shape is formed and that has magnetic power and having the other surface of the exterior contact an external surface of a central roll so that the exterior is attached to the central roll having magnetic power by magnetic power. Therefore, the method of manufacturing a roll for roll printing/roll imprinting capable of reducing production cost to massively manufacture the roll for roll printing/roll imprinting is provided.

Abstract: A lithography apparatus is provided. The lithography apparatus includes: a polarizing filter that converts incident light to first polarized light having a single polarizing direction; and a photo mask that is disposed to be separated from the polarizing filter and in which a polarizing pattern having a polarization axis of a predetermined direction in order to convert the applied first polarized light to second polarized light by adjusting a transmittance of the first polarized light and a light blocking pattern that blocks the first polarized light are formed, wherein by radiating light in which a transmittance is adjusted in the photo mask, the photoresist is patterned.

Abstract: A device for forming a surface pattern of fluid includes: fluid that can be hardened under a predetermined condition; a base unit to which the fluid is applied; and a vibration unit for vibrating the applied fluid to form a waveform on a surface of the fluid. A method for forming a surface pattern of fluid includes: a fluid receiving stage for applying fluid to a base unit; a vibration stage for vibrating the fluid applied to the base unit to form a waveform on a surface of the fluid; and a hardening stage for hardening the fluid on which the waveform is formed. The disclosed device for forming a surface pattern of fluid and the forming method thereof have an advantage of easily forming various waveform patterns on the surface of the fluid by a vibration unit for vibrating the fluid with various waveforms, frequencies, and amplitudes.