Patents by Inventor Yeyu Cao

Yeyu Cao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CAMPTOTHECIN DERIVATIVES
    Publication number: 20120165522
    Abstract: Various 14-Nitro, 14-amino, and 14-substituted amino camptothecin derivatives are useful in the treatment of cancer and other hyperproliferative diseases. Various 14-nitro camptothecin derivatives are conveniently prepared by reacting a camptothecin derivative with fuming nitric acid, optionally employing acetic anhydride as a solvent.
    Type: Application
    Filed: June 16, 2010
    Publication date: June 28, 2012
    Inventors: Xiaohong Cai, Jian-Xin Duan, Mark Matteucci, Yeyu Cao, Hailong Jiao
  • Bicycloheteroaryl compounds as P2X7 modulators and uses thereof
    Patent number: 8093265
    Abstract: Compounds are disclosed that have a formula represented by the following: The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, pain, inflammation, traumatic injury, and others.
    Type: Grant
    Filed: March 7, 2008
    Date of Patent: January 10, 2012
    Assignee: Renovis, Inc.
    Inventors: Michael G. Kelly, John Kincaid, Yunfeng Fang, Yeyu Cao, Carl Kaub, Sumithra Gowlugari, Zhan Wang
  • AMIDE COMPOUNDS, COMPOSITIONS AND USES THEREOF
    Publication number: 20110237578
    Abstract: Compounds are provided according to formula (I), where A, B, W, X?, L, R1, R3, R4b, and m? are as defined herein. Provided compounds and pharmaceutical compositions thereof are useful for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, pain, inflammation, cognitive disorders, anxiety, depression, and others.
    Type: Application
    Filed: September 14, 2009
    Publication date: September 29, 2011
    Inventors: Zhi-Liang Wei, Sumithra Gowlugari, Carl Kaub, Zhan Wang, Yeyu Cao, John Kincaid
  • Bicycloheteroaryl Compounds As P2X7 Modulators and Uses Thereof
    Publication number: 20110118287
    Abstract: Bicycloheteroaryl compounds are disclosed that have formula (I). The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, pain, inflammation, traumatic injury, and others.
    Type: Application
    Filed: March 16, 2007
    Publication date: May 19, 2011
    Applicant: RENOVIS, INC.
    Inventors: Michael G. Kelly, John Kincaid, Yunfeng Fang, Jianhua He, Yeyu Cao, Carl Kaub, Sumithra Gowlugari
  • Bicycloheteroaryl compounds as P2X7 modulators and uses thereof
    Publication number: 20110092476
    Abstract: Bicycloheteroaryl compounds are disclosed that have a formula represented by the following: The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, pain, inflammation, traumatic injury, and others.
    Type: Application
    Filed: October 18, 2010
    Publication date: April 21, 2011
    Inventors: Michael G. Kelly, John Kincaid, Yunfeng Fang, Jianhua He, Yeyu Cao, Carl Kaub, Sumithra Gowlugari, Zhan Wang
  • AMIDE COMPOUNDS, COMPOSITIONS AND USES THEREOF
    Publication number: 20110065681
    Abstract: Compounds are provided according to formula 1: where A, B, W, X?, L, R1, R3, R4b, and m? are as defined herein. Provided compounds and pharmaceutical compositions thereof are useful for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, pain, inflammation, cognitive disorders, anxiety, depression, and others.
    Type: Application
    Filed: February 27, 2009
    Publication date: March 17, 2011
    Inventors: Zhi-Liang Wei, Sumithra Gowlugari, Carl Kaub, Zhan Wang, Yeyu Cao, John Kincaid
  • Biclycloheteroaryl Compounds as P2x7 Modulators and Uses Thereof
    Publication number: 20100298285
    Abstract: Bicycloheteroaryl compounds are disclosed that have a formula represented by the following: The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, pain, inflammation, traumatic injury, and others.
    Type: Application
    Filed: March 16, 2007
    Publication date: November 25, 2010
    Inventors: Michael G. Kelly, John Kincaid, Yunfeng Fang, Jianhua He, Yeyu Cao, Carl Kaub, Sumithra Gowlugari, Zhan Wang
  • Bicycloheteroaryl Compounds as P2x7 Modulators and Uses Thereof
    Publication number: 20100292235
    Abstract: Bicycloheteroaryl compounds are disclosed that have a formula represented by the following: The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, pain, inflammation, traumatic injury, and others.
    Type: Application
    Filed: March 16, 2007
    Publication date: November 18, 2010
    Inventors: Michael G. Kelly, John Kincaid, Yunfeng Fang, Jianhua He, Yeyu Cao, Carl Kaub, Sumithra Gowlugari, Zhan Wang
  • Bicycloheteroaryl compounds as P2Xmodulators and uses thereof
    Patent number: 7816371
    Abstract: Bicycloheteroaryl compounds are disclosed that have a formula represented by the following: The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, pain, inflammation, traumatic injury, and others.
    Type: Grant
    Filed: March 16, 2007
    Date of Patent: October 19, 2010
    Assignee: Renovis, Inc.
    Inventors: Michael G. Kelly, John Kincaid, Yunfeng Fang, Jianhua He, legal representative, Yeyu Cao, Carl Kaub, Sumithra Gowlugari, Zhan Wang
  • Bicycloheteroaryl Compounds as P2X7 Modulators and Uses Thereof
    Publication number: 20100184802
    Abstract: Bicycloheteroaryl compounds are disclosed that have a formula represented by the following: The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, pain, inflammation, traumatic injury, and others.
    Type: Application
    Filed: March 16, 2007
    Publication date: July 22, 2010
    Inventors: Michael G. Kelly, John Kincaid, Yunfeng Fang, Yeyu Cao, Carl Kaub, Sumithra Gowlugari, Zhan Wang
  • NOVEL COMPOUNDS AS P2X7 MODULATORS AND USES THEREOF
    Publication number: 20100022531
    Abstract: Compounds are disclosed that have a formula represented by the following (1), the compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, pain, inflammation, traumatic injury, and others.
    Type: Application
    Filed: September 1, 2006
    Publication date: January 28, 2010
    Applicant: RENOVIS, INC.
    Inventors: John Kincaid, Yeyu Cao, Carl Kaub, David Lonergan, Michael G. Kelly
  • Bicycloheteroaryl Compounds as P2x7 Modulators and Uses Thereof
    Publication number: 20090298825
    Abstract: Bicycloheteroaryl compounds are disclosed that have a formula represented by the following: Formula (I). The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, pain, inflammation, traumatic injury, and others.
    Type: Application
    Filed: March 16, 2007
    Publication date: December 3, 2009
    Inventors: Michael G. Kelly, John Kincaid, Yunfeng Fang, Yeyu Cao, Carl Kaub, Sumithra Gowlugari, Zhan Wang
  • Bicycloheteroaryl compounds as P2X7 modulators and uses thereof
    Publication number: 20080287415
    Abstract: Compounds are disclosed that have a formula represented by the following: The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, pain, inflammation, traumatic injury, and others.
    Type: Application
    Filed: March 7, 2008
    Publication date: November 20, 2008
    Inventors: Michael G. Kelly, John Kincaid, Yunfeng Fang, Yeyu Cao, Carl Kaub, Sumithra Gowlugari, Zhan Wang
  • Bicycloheteroaryl compounds as P2X7 modulators and uses thereof
    Publication number: 20070225324
    Abstract: Bicycloheteroaryl compounds are disclosed that have a formula represented by the following: The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, pain, inflammation, traumatic injury, and others.
    Type: Application
    Filed: March 16, 2007
    Publication date: September 27, 2007
    Inventors: Michael Kelly, John Kincaid, Yunfeng Fang, Jianhua He, Yeyu Cao, Carl Kaub, Sumithra Gowlugari, Zhan Wang