Patents by Inventor Yi Jae LEE

Yi Jae LEE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230400430
    Abstract: The present disclosure relates to an electrochemical sensor for simultaneous detection of dopamine and serotonin including an electrode containing a reduced graphene oxide (rGO), poly(3,4-ethylenedioxythiophene):poly(4-styrenesulfonate) (PEDOT:PSS), and Nafion, wherein the sensor has high interfacial conductivity and electrocatalytic properties and further improves the negatively charged electrode interface, thereby enabling high sensitivity selective measurement of dopamine and serotonin. In addition, since the sensor according to the present disclosure is stable for a long time and has high reproducibility, it can be used for clinical diagnosis of various brain and neurological diseases, drug treatment, biological research using changes in the concentration of neurotransmitters, and biochip application fields.
    Type: Application
    Filed: April 18, 2023
    Publication date: December 14, 2023
    Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Yi Jae LEE, Seung Hyeon KO
  • Patent number: 11668709
    Abstract: The present disclosure relates to a system for monitoring post-translational modification of protein using a biosensor with a gap, which performs with high reliability a diagnosis of a disease associated with a target protein for which impedance is measured, by measuring an impedance of a sample introduced into a sensor and calculating a change rate of the measured impedance, and to a method of manufacturing the biosensor used for the system.
    Type: Grant
    Filed: September 24, 2019
    Date of Patent: June 6, 2023
    Assignee: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Soo Hyun Lee, Ji Yoon Kang, Hyewhon Rhim, Yi Jae Lee, Hyewon Seo, Yun Kyung Kim
  • Publication number: 20220381722
    Abstract: The present invention relates to a sensor for dopamine-selective detection, a preparation method therefor, and use thereof.
    Type: Application
    Filed: May 18, 2022
    Publication date: December 1, 2022
    Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Yi Jae LEE, Seunghyeon KO
  • Publication number: 20200110099
    Abstract: The present disclosure relates to a system for monitoring post-translational modification of protein using a biosensor with a gap, which performs with high reliability a diagnosis of a disease associated with a target protein for which impedance is measured, by measuring an impedance of a sample introduced into a sensor and calculating a change rate of the measured impedance, and to a method of manufacturing the biosensor used for the system.
    Type: Application
    Filed: September 24, 2019
    Publication date: April 9, 2020
    Inventors: Soo Hyun Lee, Ji Yoon KANG, Hyewhon RHIM, Yi Jae LEE, Hyewon SEO, Yun Kyung KIM