Patents by Inventor Yi-Zhou Quan

Yi-Zhou Quan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TREATMENT OF HEARING LOSS
    Publication number: 20230277574
    Abstract: Compositions for regeneration of inner cells and for treating hearing loss comprise at least one modulator of mechanistic target of rapamycin (mTOR) sufficient to induce reprogramming proliferation and regeneration of inner ear cells. The composition include, in some instances, an effective amount of one or more phosphatase and tensin homolog (PTEN) inhibitors, MYC/NOTCH modulators, Atonal Homolog 1 (Atoh1) modulators or combinations thereof.
    Type: Application
    Filed: January 13, 2023
    Publication date: September 7, 2023
    Inventors: Zheng-Yi Chen, Wenyan Li, Yi-Zhou Quan
  • Treatment of hearing loss
    Patent number: 11590152
    Abstract: Compositions for regeneration of inner cells and for treating hearing loss comprise at least one modulator of mechanistic target of rapamycin (mTOR) sufficient to induce reprogramming proliferation and regeneration of inner ear cells. The composition include, in some instances, an effective amount of one or more phosphatase and tensin homolog (PTEN) inhibitors, MYC/NOTCH modulators, Atonal Homolog 1 (Atoh1) modulators or combinations thereof.
    Type: Grant
    Filed: January 28, 2019
    Date of Patent: February 28, 2023
    Assignee: Massachusetts Eye and Ear Infirmary
    Inventors: Zheng-Yi Chen, Wenyan Li, Yi-Zhou Quan
  • TREATMENT OF HEARING LOSS
    Publication number: 20210030775
    Abstract: Compositions for regeneration of inner cells and for treating hearing loss comprise at least one modulator of mechanistic target of rapamycin (mTOR) sufficient to induce reprogramming proliferation and regeneration of inner ear cells. The composition include, in some instances, an effective amount of one or more phosphatase and tensin homolog (PTEN) inhibitors, MYC/NOTCH modulators, Atonal Homolog 1 (Atoh1) modulators or combinations thereof.
    Type: Application
    Filed: January 28, 2019
    Publication date: February 4, 2021
    Inventors: Zheng-Yi Chen, Wenyan Li, Yi-Zhou Quan