Abstract: An apparatus comprises a mount body by which the apparatus is secured to a structure. A camera assembly includes an image sensor adapted to capture images within its field of view. A lighting assembly houses one or more light sources including a directional light source. A control-board assembly, fixed to the mount body, houses control boards including one or more processors configured to acquire information about an object, to associate a location within the field of view of the image sensor with the object, to point light emitted by the directional light source at the location associated with the object by rotating the lighting assembly and turning the laser assembly, and, based on an image acquired from the camera assembly, to detect change within the field of view of the image sensor corresponding to placement or removal of the object.

Abstract: An apparatus for helping locate an item of interest in or near a building comprises an indicator and a body with a pair of pincers adapted to operate in opposition to grasp or be placed on or near the item of interest. The body houses a radiofrequency (RF) receiver configured to receive RF signals transmitted by an RF transmitter, and a processor in communication with the RF receiver and the indicator. The processor is configured to acquire information from the RF signals that are received by the RF receiver and to turn on the indicator in response to the information acquired from the RF signals.

Abstract: An apparatus comprises a mount body by which the apparatus is secured to a structure. A camera assembly includes an image sensor adapted to capture images within its field of view. A lighting assembly houses one or more light sources including a directional light source. A control-board assembly fixed to the mount body, houses control boards including one or more processors configured to acquire information about an object, to associate a location within the field of view of the image sensor with the object, to point light emitted by the directional light source at the location associated with the obj ect by rotating the lighting assembly and turning the laser assembly, and, based on an image acquired from the camera assembly, to detect change within the field of view of the image sensor corresponding to placement or removal of the object.

Abstract: The present invention relates to certain compounds of Formula Ia and pharmaceutical compositions thereof that modulate the activity of the cannabinoid CB2 receptor. The present invention further relates to certain compounds of Formula Ia and pharmaceutical compositions thereof that modulate the activities of both the CB1 receptor and the CB2 receptor.

Abstract: Provided herein are compounds which are useful as antagonists of the muscarinic acetylcholine receptor M1 (mAChR M1); synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating neurological and psychiatric disorders associated with muscarinic acetylcholine receptor dysfunction using the compounds and compositions.

Abstract: Provided herein are compounds which are useful as antagonists of the muscarinic acetylcholine receptor M1 (mAChR M1); synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating neurological and psychiatric disorders associated with muscarinic acetylcholine receptor dysfunction using the compounds and compositions.

Abstract: Imidazo[1,2-?]pyridine derivatives of Formula (Ia) and pharmaceutical compositions thereof that modulate the activity of the 5-HT2A serotonin receptor. Compounds and pharmaceutical compositions thereof are directed to methods useful in the treatment of insomnia, dyssomnia, parasomnia and related sleep disorders, platelet aggregation, coronary artery disease, myocardial infarction, transient ischemic attack, angina, stroke, atrial fibrillation, thrombosis, asthma or symptoms thereof, agitation or symptoms thereof, behavioral disorders, drug induced psychosis, excitative psychosis, Gilles de la Tourette's syndrome, manic disorder, organic or NOS psychosis, psychotic disorders, psychosis, acute schizophrenia, chronic schizophrenia, NOS schizophrenia and related disorders, diabetic-related disorders, progressive multifocal leukoencephalopathy and the like.

Abstract: Provided are certain methods useful in the treatment of cancer comprising administering a compound of Formula Ia and pharmaceutical compositions thereof that modulate the activity of the cannabinoid CB2 receptor;

Abstract: An apparatus for helping locate an item of interest in or near a building comprises an indicator and a body with a pair of pincers adapted to operate in opposition to grasp or be placed on or near the item of interest. The body houses a radiofrequency (RF) receiver configured to receive RF signals transmitted by an RF transmitter, and a processor in communication with the RF receiver and the indicator. The processor is configured to acquire information from the RF signals that are received by the RF receiver and to turn on the indicator in response to the information acquired from the RF signals.

Abstract: The present invention relates to certain 3-phenyl-pyrazole derivatives of Formula (Ia) and pharmaceutical compositions thereof that modulate the activity of the 5-HT2A serotonin receptor. Compounds and pharmaceutical compositions thereof are directed to methods useful in the treatment of platelet aggregation, coronary artery disease, myocardial infarction, transient ischemic attack, angina, stroke, atrial fibrillation, reducing the risk of blood clot formation, asthma or symptoms thereof, agitation or a symptom, behavioral disorders, drug induced psychosis, excitative psychosis, Gilles de la Tourette's syndrome, manic disorder, organic or NOS psychosis, psychotic disorder, psychosis, acute schizophrenia, chronic schizophrenia, NOS schizophrenia and related disorders, and sleep disorders, sleep disorders, diabetic-related disorders, progressive multifocal leukoencephalopathy and the like.

Abstract: An apparatus comprises a mount body by which the apparatus is secured to a structure. A camera assembly, fixed to the mount body, includes an image sensor adapted to capture images within its field of view. A lighting assembly, rotatably connected to the mount body, houses one or more light sources including a directional light source. A control-board assembly, fixed to the mount body, houses control boards including one or more processors configured to acquire information about an object, to associate a location within the field of view of the image sensor with the object, to point light emitted by the directional light source at the location associated with the object by rotating the lighting assembly and turning the laser assembly, and, based on an image acquired from the camera assembly, to detect change within the field of view of the image sensor corresponding to placement or removal of the object.

Abstract: Provided are certain methods useful in the treatment of cancer comprising administering a compound of Formula Ia and pharmaceutical compositions thereof that modulate the activity of the cannabinoid CB2 receptor;

Abstract: Systems and methods improve virtual reality and augmented reality functionality for mobile devices using radio frequency (RF) signals transmitted by a tracked device and received at four or more spatially separated antennae. These antennae are connected, wirelessly or through wired connections, to a base station. Through RF signal time of arrival information acquired at the antennae, the base station can continuously determine accurate position information of the tracked device, without lighting or line of sight limitations experienced by camera and other optical systems. As the position of the RF-transmitting tracked device is registered within a virtual environment produced by an interactive software program in communication with (or part of) the base station, the virtual viewpoint of the tracked device is controlled to reflect the relative position and orientation of the tracked device with respect to the virtual environment produced by the software program and displayed on a view screen.

Abstract: Provided are certain methods useful in the treatment of pain comprising administering a compound of Formula Ia and pharmaceutical compositions thereof that modulate the activity of the cannabinoid CB2 receptor;

Abstract: Pyrazolc derivatives of Formula (Ia) and pharmaceutical compositions thereof that modulate the activity of the serotonin 5HT2A receptor. Formula (Ia). Compounds and pharmaceutical compositions thereof are directed to methods useful in the treatment of insomnia and related sleep disorders, platelet aggregation, coronary artery disease, myocardial infarction, transient ischemic attack, angina, stroke, atrial fibrillation, reducing the risk of blood clot formation, asthma or symptoms thereof, agitation or symptoms thereof, behavioral disorders, drug induced psychosis, excitative psychosis, Gilles de la Tourette's syndrome, manic disorder, organic or NOS psychosis, psychotic disorders, psychosis, acute schizophrenia, chronic schizophrenia. NOS schizophrenia and related disorders, diabetic-related disorders, progressive multifocal leukoencephalopathy and the like.

Abstract: The present invention relates to certain compounds of Formula Ia and pharmaceutical compositions thereof that modulate the activity of the cannabinoid CB2 receptor. The present invention further relates to certain compounds of Formula Ia and pharmaceutical compositions thereof that modulate the activities of both the CB1 receptor and the CB2 receptor.

Abstract: Systems and methods for position tracking include at least three spatially separated radio-frequency (RF) sources of radio signals. Each RF source is disposed in an area at a location known to that RF source. Each RF source includes an RF transmitter configured to transmit radio signals that carry a unique identifier and the known location of that RF source. The position tracking system and method include at least one tag. Each tag is coupled to a different mobile object and includes a radio module with an RF receiver for receiving the radio signals transmitted by the at least three spatially separated RF sources. Each tag further includes memory and a processor that executes executable code stored in the memory to compute a range from that tag to each of the at least three RF sources and to compute a position of that tag based on at least three computed ranges.

Abstract: The present invention relates to certain 3-phenyl-pyrazole derivatives of Formula (Ia) and pharmaceutical compositions thereof that modulate the activity of the 5-HT2A serotonin receptor. Compounds and pharmaceutical compositions thereof are directed to methods useful in the treatment of platelet aggregation, coronary artery disease, myocardial infarction, transient ischemic attack, angina, stroke, atrial fibrillation, reducing the risk of blood clot formation, asthma or symptoms thereof, agitation or a symptom, behavioral disorders, drug induced psychosis, excitative psychosis, Gilles de la Tourette's syndrome, manic disorder, organic or NOS psychosis, psychotic disorder, psychosis, acute schizophrenia, chronic schizophrenia, NOS schizophrenia and related disorders, and sleep disorders, sleep disorders, diabetic-related disorders, progressive multifocal leukoencephalopathy and the like.

Abstract: Pyrazole derivatives of Formula (Ia) and pharmaceutical compositions thereof that modulate the activity of the serotonin 5HT2A receptor. Formula (Ia). Compounds and pharmaceutical compositions thereof are directed to methods useful in the treatment of insomnia and related sleep disorders, platelet aggregation, coronary artery disease, myocardial infarction, transient ischemic attack, angina, stroke, atrial fibrillation, reducing the risk of blood clot formation, asthma or symptoms thereof, agitation or symptoms thereof, behavioral disorders, drug induced psychosis, excitative psychosis, Gilles de la Tourette's syndrome, manic disorder, organic or NOS psychosis, psychotic disorders, psychosis, acute schizophrenia, chronic schizophrenia, NOS schizophrenia and related disorders, diabetic-related disorders, progressive multifocal leukoencephalopathy and the like.

Abstract: Systems and methods improve virtual reality and augmented reality functionality for mobile devices using radio frequency (RF) signals transmitted by a tracked device and received at four or more spatially separated antennae. These antennae are connected, wirelessly or through wired connections, to a base station. Through RF signal time of arrival information acquired at the antennae, the base station can continuously determine accurate position information of the tracked device, without lighting or line of sight limitations experienced by camera and other optical systems. As the position of the RF-transmitting tracked device is registered within a virtual environment produced by an interactive software program in communication with (or part of) the base station, the virtual viewpoint of the tracked device is controlled to reflect the relative position and orientation of the tracked device with respect to the virtual environment produced by the software program and displayed on a view screen.