Abstract: Provided are a cell strain for producing a biosimilar drug of Ustekinumab and a production method therefor. Specifically, provided is a Chinese hamster ovary cell S cell strain. The cell strain expresses a full human monoclonal antibody directed against the P40 subunit shared by human IL-12 and human IL-23. The fully human monoclonal antibody directed against the P40 subunit shared by human IL-12 and human IL-23 is a biosimilar drug of Ustekinumab, which not only exhibits high consistency with Ustekinumab in pre-clinical research, but also passes pharmacokinetic bioequivalence and safety similarity evaluation in clinical research. The biosimilar drug of Ustekinumab is the first one that has entered clinical trials in China, is the only one that has completed the I stage clinical trial, and is also one of the biosimilar drugs of Ustekinumab, which has the fastest progress in new drug application in the world.

Abstract: A method for producing a surface finish on an electrically conductive substrate includes transferring an ink having a plurality of electrically conductive particles onto an area of a predetermined form and/or size on a surface of the electrically conductive substrate by gravure and/or flexo printing. The ink is heated to a temperature that is higher than a melting point of the electrically conductive particles to create a melt. The melt solidifies into the surface finish on the electrically conductive substrate.

Abstract: An bifunctional surface for antimicrobial applications is described. The bifunctional surface comprises a polymer composite comprising of a mixtures of a polymer, at least one antimicrobial additive and an optional hydrophobic additive.

Abstract: An antimicrobial polymer composite is described. The antimicrobial polymer composite comprises a polymer, at least one antimicrobial additive, at least one flame retardant and at least one hydrophobic additive. An apparatus formed from an antimicrobial polymer composite is also described.

Abstract: An antimicrobial product comprising an inner layer and an outer layer surrounding said inner layer wherein said inner layer is crosslinked. The outer layer includes at least one antimicrobial additive. A process of forming such antimicrobial product using extrusion is described.

Abstract: A method of manufacturing an electrical connector and an electrical connector with a layer or primer with a free radical initiator dissolved therein which is applied to the connector housing. An oil-bleeding liquid silicone is applied to the layer or primer. The layer or primer crosslinks with the oil-bleeding liquid silicone to adhere the oil-bleeding liquid silicone. The method includes applying a layer or primer with a free radical initiator dissolved therein to the housing; applying an oil-bleeding liquid silicone to the primer; and crosslinking the oil-bleeding liquid silicone to the layer or primer to adhere the oil-bleeding silicone.

Abstract: At least a computer program product comprising computing instructions stored on a non-transitory computer storage medium is provided. The computer program product is provided for efficiently encoding or decoding a video frame to smooth out or reduce visual distortions such as visual artifact between different video subsections encoded with different compression methods within a video frame. In addition, an improved memory storage is provided for applying a raster scan search strategy for finding a reference image for the input video frame by applying a shift-based input addressing scheme to write to the memory storage and a corresponding shift-based output addressing scheme to read from the memory storage.

Abstract: At least a method and an apparatus are provided for efficiently encoding or decoding a video frame, and more particularly, to a method or an apparatus for efficiently providing an improved slice based pipelined coding/decoding with low latency. In particular, each video frame of a sequence of video frames are segmented into equal number of slices, with only one slice per video frame. In addition, the position of the only I slice changes sequentially for the each video frame of the sequence of video frames over time, forming a sawtooth pattern.

Abstract: At least a method and an apparatus are provided for efficiently encoding or decoding a video frame to smooth out or reduce visual distortions such as visual artifact between different video subsections encoded with different compression methods within a video frame. In addition, an improved memory storage is provided for applying a raster scan search strategy for finding a reference image for the input video frame by applying a shift-based input addressing scheme to write to the memory storage and a corresponding shift-based output addressing scheme to read from the memory storage.

Abstract: A hybrid silicone composite for high temperature insulation applications is disclosed. The hybrid silicone composite is formed of a mixture of liquid high consistency silicone rubber and solid high consistency silicone rubber and a thermally decomposable inorganic filler which are compounded together. The compounded material is then injection molded, over molded, compression molded, cast, laminated, extruded, calendered, adhered or dispensed. When the silicone composite is exposed to a high temperature, it forms an inorganic composite and maintains its insulating properties and dimensional stability.

Abstract: A silicone composite for high temperature insulation applications is disclosed. The composite is formed of a silicone and a thermally decomposable inorganic filler which are compounded together. The compounded material is then injection molded, overmolded, compression molded, cast, laminated, extruded, or dispensed. When the silicone composite is exposed to a high temperature, it forms an inorganic composite and maintains its insulating properties and dimensional stability.

Abstract: Provided are antibodies and fragments against human interleukin-4 receptor alpha (hIL-4R?) and uses thereof. The antibodies and fragments preferably have heavy chain complementary determining regions as set forth in SEQ ID NOs: 1-3 or 14-16 and light chain complementary determining regions as set forth in SEQ ID NOs: 4-6 or 17-19.

Abstract: Disclosed by the present invention are an anti-human interleukin 17A monoclonal antibody and an application thereof. The epitope of the monoclonal antibody binding to human interleukin 17A comprises 78th asparagine (N78). The antibody may be used to treat rheumatoid arthritis, psoriasis, multiple sclerosis, psoriatic arthritis, plaque psoriasis and/or ankylosing spondylitis.

Abstract: A silicone composite for high temperature insulation applications is disclosed. The composite is formed of a silicone and a thermally decomposable inorganic filler which are compounded together. The compounded material is then injection molded, overmolded, compression molded, cast, laminated, extruded, or dispensed. When the silicone composite is exposed to a high temperature, it forms an inorganic composite and maintains its insulating properties and dimensional stability.

Abstract: A process for ultrasonically consolidating particulates in an ink onto a substrate at ambient temperatures in less than 5 seconds to form a completely dense, well adhered functional coatings is disclosed. The coating can be used for electronic components. The process is applicable to various substrates such as metals, plastics and ceramics.

Abstract: A method of producing a solderable aluminum contact comprises formulating an ink, applying the ink to an aluminum substrate to form an ink layer on a surface of the aluminum substrate, and melting the ink layer. The ink includes a solderable element that is conductive. The melting of the ink layer forms an alloy on the surface of the aluminum substrate including the solderable element.

Abstract: A lighting device includes a base, a transparent cover, an electronic circuit mounted to the base, and an antenna. The electronic circuit is connectable with a light emitting element adapted to emit a light through the transparent cover and/or a light receiving element adapted to receive a light through the transparent cover. The antenna has a radiating patch following a contour of an inner surface of the transparent cover and connected to the electronic circuit.

Abstract: The present invention relates to an enhanced performance ultraconductive copper composite structure. The ultraconductive copper composite structure comprises at least two composite layers in which the interface between the two composite layers is sufficiently close to the surface of the ultraconductive copper composite so as to enhance the RF conductivity of the ultraconductive copper composite. The present invention also provides for method of forming such a ultraconductive copper composite structure.

Abstract: Processes for preparing stabilized metal-containing nanoparticles comprising silver and/or a silver alloy composite by reacting a silver compound with a reducing agent comprising a hydrazine compound at a temperature between about 20° C. and about 60° C. The reaction being carried out by incrementally adding the silver compound or a mixture of the silver compound and a stabilizer to a solution comprising the reducing agent, a stabilizer, and a solvent. Conductive ink compositions containing stabilized metal-containing nanoparticles prepared by such processes.

Abstract: A method of forming a conductive trace that includes steps of A) selecting a substrate, B) providing a jet dispenser, C) selecting a conductive ink, D) measuring the ink's viscosity (Vm), E) using Vm to select one of criteria (i)-(iv), F) applying the selected criteria to the dispenser, and G) applying the ink onto the substrate; and drying, curing, or annealing the ink to form the conductive trace having ?4B adhesion. The criteria (i)-(iv) include: (i) (Vm) >2.0 Pa-s, then (1) add a fluid—repeat D)-E) or (2) repeat C)-E); (ii) 2.0 Pa-s?Vm>0.35 Pa-s, use needle diameter ?3.0 mm & nozzle diameter (d) ?0.15 mm with ratio of nozzle length (L) to nozzle diameter (d) ?30; (iii) Vm<0.25 Pa-s, use a needle diameter ?1.0 mm and <3.0 mm & nozzle diameter ?0.15 mm with L/d ?30; or (iv) 0.25 Pa-s?Vm?0.35 Pa-s, use criteria (ii) or (iii).