Abstract: A probiotic composition for improving an effect of a chemotherapeutic drug of Gemcitabine on inhibiting pancreatic cancer is disclosed in the present disclosure. The probiotic composition comprises an effective amount of Lactobacillus paracasei GMNL-133, an effective amount of Lactobacillus reuteri GMNL-89, and a pharmaceutically acceptable carrier, wherein the Lactobacillus paracasei GMNL-133 was deposited in the China Center for Type Culture Collection on Sep. 26, 2011 under an accession number CCTCC NO. M 2011331, and the Lactobacillus reuteri GMNL-89 was deposited in the China Center for Type Culture Collection on Nov. 19, 2007 under an accession number CCTCC NO. M 207154. A method for improving the effect of the chemotherapeutic drug of Gemcitabine on inhibiting pancreatic cancer is further disclosed in the present disclosure.

Abstract: Provided are an anti-wrinkle composition, an anti-wrinkle microneedle patch and a preparation method thereof. The anti-wrinkle microneedle patch comprises a base and multiple needles, the base has an upper surface, and the needles are formed on the upper surface; wherein, a material of each needle comprises a low-molecular hyaluronic acid, a modified hyaluronic acid and a cross-linked hyaluronic acid. A weight ratio of the modified hyaluronic acid to the low-molecular hyaluronic acid is 0.1 to 4, and a weight ratio of the modified hyaluronic acid to the cross-linked hyaluronic acid is less than 30. Accordingly, the anti-wrinkle microneedle patch has effects of moisturizing the skin, elevating the thickness and the strength of the skin, and smoothing and reducing the wrinkles.

Abstract: Provided is a microneedle patch comprising a substrate part and multiple needle parts protruding from the substrate part. The substrate part consists of a diffusion-proof layer and a base, and each needle part consists of a needle tip, a diffusion-proof layer and a base. The diffusion-proof layer of each needle part is formed between the needle tip and the base of the corresponding needle part. The diffusion-proof layer of the substrate part and the diffusion-proof layer of needle part are one-piece structures, and so are the base of the substrate part and the base of the needle part. The diffusion-proof layer of the microneedle patch can prevent the active ingredients from diffusing to the base, limit the active ingredients to the needle tip and control the carrying quantity thereof.

Abstract: An electrophoretic display and a driving method thereof are provided. The electrophoretic display includes a display panel, a storage unit and a timing controller. The display panel has a plurality of sub pixels. The storage unit stores a plurality of sets of multiple-grayscale driving waveforms, in which the driving voltage scales of driving waveforms corresponding to a same grayscale in the sets of multiple-grayscale driving waveforms are different from each other. The timing controller is coupled to the storage unit and the display panel and receives an image signal, and when the image signal transmits a multiple-grayscale frame, the timing controller sequentially adopts the sets of multiple-grayscale driving waveforms to drive the sub pixels.

Abstract: An electrophoretic display and a driving method thereof are provided. The electrophoretic display includes a display panel, a storage unit, a timing controller (TCON). The display panel has a plurality of sub-pixels. The storage unit stores a plurality sets of driving waveforms, wherein the lengths of driving waveforms in the sets of driving waveforms are different from each other. The TCON has an analysis module, couples to the display panel and the storage unit, and receives an image signal having a plurality of display data. The analysis module analyzes the display data to obtain a analysis result. The TCON selects one of the sets of driving waveforms according to the analysis result, and drives the sub-pixels according to the selected set of driving waveforms.