Patents by Inventor Ying Wan
Ying Wan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11938476Abstract: A biochemical analysis system capable of sample preparation and processing can include at least one inlet channel having a non-fouling, slippery surface to autonomously transport a fluid sample to a chamber by a geometry of the at least one inlet channel. The at least one inlet channel can include a first end, which is open and exposed, and a second end connected to the chamber for mixing and reaction of the fluid sample, and the at least one inlet channel can include a converging or diverging angle.Type: GrantFiled: May 20, 2022Date of Patent: March 26, 2024Assignee: The Penn State Research FoundationInventors: Pak Kin Wong, Tak-Sing Wong, Jing Wang, Hui Li, Yi Lu, Ying Wan
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Patent number: 11918635Abstract: A method and a platform for detecting an immunogenicity of a tumor neoantigen are provided. Specifically, the detection method includes the following steps: culturing human peripheral blood monocytes ex vivo for 13 days, adding an antigenic peptide fragment of human influenza virus and stimulating and activating cytokines, antigenic peptides, and immunoadjuvants during the 13 days, and finally conducting enzyme-linked immunospot (ELISPOT) chromogenic reaction and instrument-based scanning, counting, and analysis to detect the immunogenicity of tumor neoantigen. An application of the detection method and platform in biomedicine is provided. Compared with the prior art, the detection method and platform have advantages and characteristics of a short detection period, high convenience, low consumption of experimental cells, and low detection cost. Therefore, the detection method and platform can be used for ex vivo high-throughput assay for the immunogenicity of the tumor neoantigen.Type: GrantFiled: August 21, 2020Date of Patent: March 5, 2024Assignees: NeoCura Bio-Medical Technology Co., Ltd, Beijing Neocurna Biotechnology corporation, Shenzhen Neocurna Biotechnology corporationInventors: Youdong Pan, Qi Song, Ji Wan, Jun-Yuan Huang, An Xiao, Gang Liu, Ying Wen
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Patent number: 11917598Abstract: A method, base station and user equipment are provided for wireless communication. The method can include steps: transmitting data on a first frequency band; transmitting, on a second frequency band, a detection signal for detecting a channel condition of the second frequency band; generating channel condition information about the second frequency band based on the received detection signal; feeding back the channel condition information via the first frequency band; and selecting a current data transmission frequency band based at least in part on the feedback channel condition information about the second frequency band and/or traffic requirement information; wherein the current data transmission frequency band is any one of the first frequency band, the second frequency band or a cooperative transmission of the first frequency band with the second frequency band.Type: GrantFiled: June 30, 2021Date of Patent: February 27, 2024Assignee: XIDIAN UNIVERSITYInventors: Xiaohui Li, Siting Lv, Hongjie Wan, Ying Li
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Publication number: 20230087950Abstract: In the technical field of lithium ion batteries, disclosed is a wet synthesis method of a high-nickel NCMA quaternary precursor. The method includes synthesizing solid tiny crystal nuclei of the NCMA quaternary precursor in a first reactor, and prompting the crystal nuclei of the quaternary precursor to grow to a certain particle size in a second reactor, wherein in the first reactor, an upper feeding mode is used to continuously produce the solid tiny crystal nuclei of the NCMA quaternary precursor. In the second reactor, an upper-and-lower dual feeding mode is used to prompt the continuous growth of the solid tiny crystal nuclei of the NCMA quaternary precursor. During a washing process, the NCMA quaternary precursor is washed with a mixed alkali solution of sodium carbonate and sodium hydroxide at certain concentration, so that Na can be reduced below 50 ppm and sulfur can be reduced below 800 ppm.Type: ApplicationFiled: February 18, 2020Publication date: March 23, 2023Inventors: Zhongqiang LIU, Xiaoyan ZHANG, Bihuang HU, Feng XIONG, Lixia FAN, Yanmiao HE, Donghua NING, Kaizhong FU, Sikang CHEN, Shibo ZHONG, Ying WAN, Rui YAO, Mengdi LI
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Publication number: 20220274103Abstract: A biochemical analysis system capable of sample preparation and processing can include at least one inlet channel having a non-fouling, slippery surface to autonomously transport a fluid sample to a chamber by a geometry of the at least one inlet channel. The at least one inlet channel can include a first end, which is open and exposed, and a second end connected to the chamber for mixing and reaction of the fluid sample, and the at least one inlet channel can include a converging or diverging angle.Type: ApplicationFiled: May 20, 2022Publication date: September 1, 2022Inventors: Pak Kin WONG, Tak-Sing WONG, Jing WANG, Hui LI, Yi LU, Ying WAN
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Publication number: 20220213704Abstract: Provided are a foundation bolt pre-embedding positioning mold and a method for mounting a foundation bolt, including a centerline positioning assembly and a vertical positioning assembly for mounting on foundation steel bar, wherein the centerline positioning assembly includes a positioning template horizontally arranged, a positioning portion is formed on the positioning template, the positioning portion extends along a first direction, the positioning portion is used to overlap with a preset centerline in a vertical direction, and the first direction is a length direction of the positioning template; the positioning template is configured to be mounted on the vertical positioning assembly, so as to fix a position of the positioning template in the vertical direction; and a first mounting hole is formed in the positioning template, so as to vertically fix the foundation bolt to the positioning template.Type: ApplicationFiled: April 16, 2021Publication date: July 7, 2022Inventors: Zhongpei Liu, Ying Wan, Yafei Geng, Yunguang Chen
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Patent number: 11351536Abstract: A biochemical analysis system capable of sample preparation and processing can include at least one inlet channel having a non-fouling, slippery surface to autonomously transport a fluid sample to a chamber by a geometry of the at least one inlet channel. The at least one inlet channel can include a first end, which is open and exposed, and a second end connected to the chamber for mixing and reaction of the fluid sample, and the at least one inlet channel can include a converging or diverging angle.Type: GrantFiled: October 29, 2018Date of Patent: June 7, 2022Assignee: The Penn State Research FoundationInventors: Pak Kin Wong, Tak-Sing Wong, Jing Wang, Hui Li, Yi Lu, Ying Wan
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Publication number: 20220135509Abstract: A synthetic method of 9,9-bis[4-(2-hydroxyethoxy)phenyl]fluorene, belonging to the technical field of chemical synthesis. 9-fluorenone, phenoxyethanol, a catalyst and a cocatalyst are stiffed in an alkane solvent and heated until refluxing, the generated water is removed from the reaction solution via an azeotropic method while reacting, the reaction solution is diluted with water after the reaction is ended, uniformly stirred and cooled to separate out crystals and then filtered, a filter cake is rinsed and dried to obtain a 9,9-bis[4-(2-hydroxyethoxy)phenyl]fluorene finished product; the filtered crystallization mother liquor is subjected to standing and layering, a water phase is removed, then an organic phase is distilled to recycle the alkane solvent, and the concentrate is rectified to recycle phenoxyethanol.Type: ApplicationFiled: January 12, 2022Publication date: May 5, 2022Inventors: Qiliang YUAN, Dongdong JIANG, Ying WAN, Yonggen SHI, Pengfei XU, Haifeng CHEN
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Patent number: 11255832Abstract: Disclosed are a device and a method for determining the solubility of elemental sulfur in a sulfur-containing gas. The device includes a displacement pump, a first sampler, a high-temperature box, a back-pressure pump, a control valve, an adsorption tank, a low-temperature box, a flow meter and a collection tank. An outlet of the displacement pump is in communication with an inlet of the first sampler; an outlet of the first sampler is in communication with a first inlet of the control valve; a second inlet of the control valve is in communication with an outlet of the back-pressure pump; an outlet of the control valve is in communication with a first opening of the adsorption tank; a second opening of the adsorption tank is in communication with the flow meter; and a third opening of the adsorption tank is in communication with the collection tank.Type: GrantFiled: May 25, 2018Date of Patent: February 22, 2022Assignees: PETROCHINA COMPANY LIMITED, SICHUAN KELITE OIL AND GAS TECHNOLOGY CO. LTD.Inventors: Li Wang, Zhao Ding, Fusen Xiao, Dihong Zhang, Daqing Tang, Jingyuan Chen, Ying Wan, Xuefeng Yang, Bo Kong, Tong Liu, Banghua Xie, Hua Zhou, Zhijin Pu
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Patent number: 10923686Abstract: A heat dissipation structure for a flexible display is disclosed, and includes: a substrate, an anode metal layer, light emitting diode elements, a pixel defining layer, a cathode metal layer, and a heat conducting insulator disposed in sequence. The pixel defining layer has grooves, and the heat conducting insulator is sandwiched between the anode metal layer and the cathode metal layer, and disposed in the grooves. The heat conducting insulator is used to connect the anode metal layer and the cathode metal layer, so as to form an electrically insulating and thermally conducting path between the anode metal layer and the cathode metal layer.Type: GrantFiled: January 17, 2019Date of Patent: February 16, 2021Assignee: Wuhan China Star Optoelectronics Semiconductor Display Technology Co., Ltd.Inventors: Ying Wan, Sheng Liu
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Publication number: 20200203655Abstract: A heat dissipation structure for a flexible display is disclosed, and includes: a substrate, an anode metal layer, light emitting diode elements, a pixel defining layer, a cathode metal layer, and a heat conducting insulator disposed in sequence. The pixel defining layer has grooves, and the heat conducting insulator is sandwiched between the anode metal layer and the cathode metal layer, and disposed in the grooves. The heat conducting insulator is used to connect the anode metal layer and the cathode metal layer, so as to form an electrically insulating and thermally conducting path between the anode metal layer and the cathode metal layer.Type: ApplicationFiled: January 17, 2019Publication date: June 25, 2020Inventors: Ying WAN, Sheng LIU
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Publication number: 20200132647Abstract: Disclosed are a device and a method for determining the solubility of elemental sulfur in a sulfur-containing gas. The device includes a displacement pump, a first sampler, a high-temperature box, a back-pressure pump, a control valve, an adsorption tank, a low-temperature box, a flow meter and a collection tank. An outlet of the displacement pump is in communication with an inlet of the first sampler; an outlet of the first sampler is in communication with a first inlet of the control valve; a second inlet of the control valve is in communication with an outlet of the back-pressure pump; an outlet of the control valve is in communication with a first opening of the adsorption tank; a second opening of the adsorption tank is in communication with the flow meter; and a third opening of the adsorption tank is in communication with the collection tank.Type: ApplicationFiled: May 25, 2018Publication date: April 30, 2020Applicants: PETROCHINA COMPANY LIMITED, SICHUAN KELITE OIL AND GAS TECHNOLOGY CO. LTD.Inventors: Li WANG, Zhao DING, Fusen XIAO, Dihong ZHANG, Daqing TANG, Jingyuan CHEN, Ying WAN, Xuefeng YANG, Bo KONG, Tong LIU, Banghua XIE, Hua ZHOU, Zhijin PU
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Publication number: 20190126268Abstract: A biochemical analysis system capable of sample preparation and processing can include at least one inlet channel having a non-fouling, slippery surface to autonomously transport a fluid sample to a chamber by a geometry of the at least one inlet channel. The at least one inlet channel can include a first end, which is open and exposed, and a second end connected to the chamber for mixing and reaction of the fluid sample, and the at least one inlet channel can include a converging or diverging angle.Type: ApplicationFiled: October 29, 2018Publication date: May 2, 2019Inventors: Pak Kin Kin WONG, Tak-Sing WONG, Jing WANG, Hui LI, Yi LU, Ying WAN
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Publication number: 20160120805Abstract: Provided are methods of treating a subject with a composition comprising an exosome or a polypeptide, RNA, or miRNA contained therein or identified or isolated therefrom. Also provided are methods of promoting dentinogenesis, amelogenesis, or osteogenesis. Also provided are compositions comprising an exosome or a polypeptide, RNA, or miRNA contained therein or identified or isolated therefrom.Type: ApplicationFiled: June 5, 2014Publication date: May 5, 2016Applicant: The Trustees of Columbia University in the City of New YorkInventors: Jeremy J. Mao, Ying Wan, Nan Jiang, Mo Chen
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Publication number: 20140057841Abstract: Disclosed is a recombinant human insulin or analog conjugate thereof. Said conjugate is formed by connecting the ?-amino group of lysine 29 of the B chain to activated polyethylene glycol by means of an amide bond. Further disclosed is a method of preparing said conjugate, a pharmaceutical compound, and a use for said conjugate in preparing medication for treating Type 1 and Type 2 diabetes.Type: ApplicationFiled: March 19, 2012Publication date: February 27, 2014Applicant: Chongqing Fagen Biomedical Inc.Inventors: Kai Fan, Yu Cao, Yong Chen, Hongliang Li, Hairong Chen, Ying Wan