Abstract: Systems, methods, and devices for inserting an intraocular lens (IOL) assembly into an eye may be provided. A device for delivery of the IOL into the eye may include a nozzle; a bay adjacent to the nozzle, wherein the bay is configured to contain the lens component and comprises a recess in a shape of a haptic extension; and a cam-actuated mechanism comprising a slider configured to move in a direction toward the nozzle; a side arm moveably disposed within the bay, wherein the side arm is positioned at an end of the slider, the end of the slider comprising a groove aligned with the side arm, wherein the groove extends from an outer edge of the slider into an interior portion of the slider, wherein the groove is angled to receive the side arm as the slider moves.

Abstract: Systems, methods, and devices for inserting an intraocular lens (IOL) assembly into an eye may be provided. A device for delivery of the IOL into the eye may include a housing; a nozzle operatively coupled to the housing; a first cylinder movably disposed within the housing; a second cylinder movably disposed within the housing, wherein the second cylinder is in fluid communication with the first cylinder; a plunger at least partially and movably disposed within the first cylinder; and a shaft movably disposed within the second cylinder, wherein the shaft is configured to move toward the lens component.

Abstract: Intraocular lens injectors described herein may include a symmetrical arranged storage compartment, nozzle passage, and plunger tip in order to symmetrically fold and provide symmetrical loading to an intraocular lens during advancement and delivery so as to avoid rotation of the intraocular lens about longitudinal, vertical, and/or lateral axes during advancement and/or delivery of the intraocular lens.

Abstract: Methods and systems are disclosed for security management in an industrial control system (ICS). An event entity detection and linking module generates a model for a plurality of event entities extracted from a plurality of different data sources including one ICS data source and one IT data source. The model encodes a set of linked event entities and their relationships, each event entity associated with a vector of attributevalue pairs. A data standardization of domain knowledge includes translating, by a machine learning application, extracted knowledge base information to rules for the constraints and using the rules to validate the constraints and to add new constraints. A fusion module performs temporal correlation detection across data streams of the different data sources for establishing causality between triplets of association models within a defined time span.

Abstract: Embodiments described herein enable tracking machine learning (“ML”) model data provenance. In particular, a computing device is configured to accept ML model code that, when executed, instantiates and trains an ML model, to parse the ML model code into a workflow intermediate representation (WIR), to semantically annotate the WIR to provide an annotated WIR, and to identify, based on the annotated WIR and ML API corresponding to the ML model code, data from at least one data source that is relied upon by the ML model code when training the ML model. A WIR may be generated from an abstract syntax tree (AST) based on the ML model code, generating provenance relationships (PRs) based at least in part on relationships between nodes of the AST, wherein a PR comprises one or more input variables, an operation, a caller, and one or more output variables.

Abstract: Apparatuses, systems, and methods for implanting an intraocular lens into an eye are described. For example, an intraocular lens injector may include a passage formed in a distal end portion of the intraocular lens injector. The passage may define an interior surface, and one or more rails may be formed on the interior surface so as to displace an optic of an intraocular lens (IOL) being advanced through the passage towards a portion of the interior surface disposed opposite the one or more rails.

Abstract: A query suggestion to expand an initial query is calculated whereby the cost of the expanded initial query is bounded in both time and quality. The user validates a subset of the top-n answers Q(G) to a query Q and provides adjusted configuration parameters. The top-n diversified ?-expansion terms Q? are calculated from the validated subset of answers Q(G) to the query Q and are provided to an interactive user interface for selection. Answers Q?(G) for the top-n diversified ?-expansion terms Q? are cost bounded by cost threshold ? and exploration range r specified by the user. The user selects a new term of terms Q? and an incremental query evaluation of the new term is invoked to compute expanded query answers Q?(G) by incrementally updating the validated subset of answers Q(G), without re-evaluating an expanded query Q? including the new term from scratch.

Abstract: Systems, methods, and apparatuses for removably attaching a drive mechanism handpiece to an intraocular lens (IOL) cartridge that folds the IOL upon removal of a cap, are provided. The IOL cartridge comprises a nozzle and a housing comprising a slide. A compartment configured to receive an IOL is disposed within the housing. An interior portion of the slide is exposed to the compartment. The nozzle is in fluid communication with the compartment. The cap covers the nozzle and the slide. The cap is configured to expose the nozzle and advance the slide to fold the IOL upon removal of the cap.

Abstract: Systems, methods, and apparatuses for inserting an intraocular lens (IOL) into an eye, are provided. An apparatus comprises an IOL cartridge comprising a nozzle, a compartment, and a plunger case. The nozzle is in fluid communication with the compartment, and the plunger case is in fluid communication with the compartment. The plunger is disposed within the plunger case. The plunger case is configured to removably attach to a handpiece.

Abstract: Systems, methods, and apparatuses for inserting an intraocular lens (IOL) into an eye, are provided. The apparatus comprises an IOL cartridge comprising a nozzle, a compartment, a plunger, and a plunger case. The nozzle is in fluid communication with the compartment, and the plunger case is in fluid communication with the compartment. The plunger is disposed within the plunger case. The plunger case includes flexible members extending from an outer surface of the plunger case. The IOL cartridge is configured to removably attach to a handpiece.

Abstract: Systems, methods, and apparatuses for storing and/or shipping an intraocular lens (IOL) cartridge are provided. A system comprises the IOL cartridge. The IOL cartridge comprises a nozzle and a compartment comprising an IOL. The nozzle is in fluid communication with the compartment. The IOL cartridge further comprises a dial disposed adjacent to the compartment, wherein an inner surface of the dial is exposed to the compartment. The dial is configured to fold the IOL upon rotation of the dial. The IOL cartridge further comprises a plunger case in fluid communication with the compartment, wherein a plunger is movably disposed within the plunger case. The IOL cartridge is configured to removably attach to a handpiece.

Abstract: Systems, methods, and apparatuses for storing and/or shipping an intraocular lens (IOL) cartridge are provided. A system comprises a packaging comprising a passage. The IOL cartridge is removably disposed within the passage. The IOL cartridge comprises a nozzle and a compartment configured to receive an IOL. The nozzle is in fluid communication with the compartment. The IOL cartridge further comprises a dial configured to rotate upon withdrawal of the IOL cartridge from the passage, wherein an inner surface of the dial is exposed to the compartment. The dial is configured to fold the IOL and release the IOL cartridge from the packaging upon rotation of the dial.

Abstract: Systems, methods, and apparatuses for removably attaching a drive mechanism handpiece to an intraocular lens (IOL) cartridge that folds the IOL upon retraction of a cap, are provided. The IOL cartridge comprises a nozzle and a compartment configured to receive an IOL. The nozzle is in fluid communication with the compartment. The IOL cartridge also includes a retractable cap that covers the nozzle and the compartment. The retractable cap is configured to expose the nozzle and fold the IOL upon retraction of the retractable cap. The IOL cartridge may also include a plunger case that is in fluid communication with the compartment, wherein a plunger is movably disposed within the plunger case.

Abstract: Systems, methods, and devices for inserting an intraocular lens (IOL) assembly into an eye may be provided. A device for delivery of the IOL into the eye may include a housing; a nozzle operatively coupled to the housing; a first cylinder movably disposed within the housing; a second cylinder movably disposed within the housing, wherein the second cylinder is in fluid communication with the first cylinder; a plunger at least partially and movably disposed within the first cylinder; and a shaft movably disposed within the second cylinder, wherein the shaft is configured to move toward the lens component.

Abstract: Systems, methods, and devices for inserting an intraocular lens (IOL) assembly into an eye may be provided. A device for delivery of the IOL into the eye may include a nozzle; a bay adjacent to the nozzle, wherein the bay is configured to contain the lens component and comprises a recess in a shape of a haptic extension; and a cam-actuated mechanism comprising a slider configured to move in a direction toward the nozzle; a side arm moveably disposed within the bay, wherein the side arm is positioned at an end of the slider, the end of the slider comprising a groove aligned with the side arm, wherein the groove extends from an outer edge of the slider into an interior portion of the slider, wherein the groove is angled to receive the side arm as the slider moves.

Abstract: An IOL injector having an automatic plunger advancement driver is described. In addition, an IOL injector having a spring-assisted driving mechanism and a spring damping mechanism is described.

Abstract: Intraocular lens (IOL) folding devices and methods of folding an IOL or components thereof are disclosed.

Abstract: Systems, methods, and devices, for delivery of a lens portion of a modular intraocular lens into an eye, may be provided. A device may include a housing; a nozzle positioned at an end of the housing, wherein an interior of the nozzle comprises a floor, the floor including an aperture; and a cam-actuated mechanism positioned within the housing, comprising: a lens stop comprising a base and a post, wherein the post is movably disposed within the aperture; and a slider configured to move in a direction toward the lens stop, wherein the lens stop is positioned at a distal end of the slider, the slider comprising a slot that is aligned with a portion of the base of the lens stop and configured to receive the portion of the base as the slider moves.

Abstract: An intraocular lens (IOL) folding device is described.

Abstract: Apparatuses, systems, and methods for implanting an intraocular lens into an eye are described. For example, an intraocular lens injector may include a plunger and an injector body that includes an insertion depth guard and a nozzle extending therefrom. The insertion depth guard is disposed at a distal end of the injector body to limit a distance that the nozzle penetrates the eye. The intraocular lens injector may also include a biasing element configured to generate a counterforce to distal movement of the plunger through the injector rod. An example intraocular lens injector may include a biasing element to produce a counterforce that opposes advancement of the plunger through the injector body. The counterforce provides for a more continuous advancement of the plunger while reducing or substantially eliminating abrupt changes in the rate at which the plunger is advanced through the injector body.