Patents by Inventor Yishai Levin

Yishai Levin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • AGENTS BINDING MODIFIED ANTIGEN PRESENTED PEPTIDES AND USE OF SAME
    Publication number: 20240029819
    Abstract: Agents binding modified antigen dependent peptides and use of same are provided. Accordingly, there is provided an agent capable of specifically binding an MHC presented peptide comprising a post translational modification (PTM), wherein the agent does not bind a peptide having the same amino acid sequence as said peptide but does not comprise said modification. Also provided are polynucleotides encoding the agent, cells expressing same and methods of use thereof. Also provided is a computer implemented method for generating a dataset of PTM on MHC bound peptides.
    Type: Application
    Filed: April 27, 2023
    Publication date: January 25, 2024
    Applicant: Yeda Research and Development Co. Ltd.
    Inventors: Yifat MERBL, Assaf KACEN, Yishai LEVIN, David MORGENSTERN
  • NON-INVASIVE ASSAY FOR DETECTING AND MONITORING SYSTEMIC INFLAMMATION
    Publication number: 20230003742
    Abstract: The invention provides assays and methods for detecting and monitoring systemic inflammation Particularly, the invention in embodiments thereof relates to the use of urinary biomarkers for non-invasive determination of the level of inflammation.
    Type: Application
    Filed: December 10, 2020
    Publication date: January 5, 2023
    Inventors: Shani Shenhar-Tsarfaty, Shlomo Avraham Berliner, Ori Rogowski, Eyal Fisher, Adi Silberman, Yishai Levin
  • METHODS OF ISOLATING BARREL-LIKE PROTEASES AND IDENTIFYING PEPTIDES PROCESSED THEREBY
    Publication number: 20210311059
    Abstract: A method of isolating barrel-like proteases is disclosed. The method comprising isolating barrel-like proteases from a biological sample containing the barrel-like proteases under conditions that maintain the content of the barrel-like protease-processed peptides in the barrel-like proteases upon isolation. A method of isolating barrel-like protease-processed peptides and a method of identifying barrel-like protease-processed peptides are also disclosed.
    Type: Application
    Filed: June 14, 2021
    Publication date: October 7, 2021
    Applicant: Yeda Research and Development Co. Ltd.
    Inventors: Yifat MERBL, Hila WOLF-LEVY, Yishai LEVIN, Bareket DASSA
  • Methods of isolating barrel-like proteases and identifying peptides processed thereby
    Patent number: 11035858
    Abstract: A method of isolating barrel-like proteases is disclosed. The method comprising isolating barrel-like proteases from a biological sample containing the barrel-like proteases under conditions that maintain the content of the barrel-like protease-processed peptides in the barrel-like proteases upon isolation. A method of isolating barrel-like protease-processed peptides and a method of identifying barrel-like protease-processed peptides are also disclosed.
    Type: Grant
    Filed: March 17, 2017
    Date of Patent: June 15, 2021
    Assignee: Yeda Research and Development Co. Ltd.
    Inventors: Yifat Merbl, Hila Wolf-Levy, Yishai Levin, Bareket Dassa
  • METHODS OF ISOLATING BARREL-LIKE PROTEASES AND IDENTIFYING PEPTIDES PROCESSED THEREBY
    Publication number: 20190033312
    Abstract: A method of isolating barrel-like proteases is disclosed. The method comprising isolating barrel-like proteases from a biological sample containing the barrel-like proteases under conditions that maintain the content of the barrel-like protease-processed peptides in the barrel-like proteases upon isolation. A method of isolating barrel-like protease-processed peptides and a method of identifying barrel-like protease-processed peptides are also disclosed.
    Type: Application
    Filed: March 17, 2017
    Publication date: January 31, 2019
    Inventors: Yifat MERBL, Hila WOLF-LEVY, Yishai LEVIN, Bareket DASSA
  • BIOMARKERS
    Publication number: 20150005192
    Abstract: The invention relates to a method of diagnosing or monitoring schizophrenia or other psychotic disorder.
    Type: Application
    Filed: September 12, 2014
    Publication date: January 1, 2015
    Applicant: Cambridge Enterprise Limited
    Inventors: Sabine Bahn, Paul Guest, Laura Harris, Yishai Levin, Divya Krishnamurthy
  • BIOMARKERS FOR SCHIZOPHRENIA
    Publication number: 20130224221
    Abstract: The invention relates to a method of diagnosing or monitoring schizophrenia or other psychotic disorder.
    Type: Application
    Filed: March 31, 2011
    Publication date: August 29, 2013
    Applicant: PSYNOVA NEUROTECH LTD.
    Inventors: Sabine Bahn, Paul Guest, Laura Harris, Yishai Levin, Divya Krishnamurthy
  • BIOMARKERS
    Publication number: 20130178385
    Abstract: The invention relates to a method of diagnosing or monitoring schizophrenia or other psychotic disorder.
    Type: Application
    Filed: May 18, 2011
    Publication date: July 11, 2013
    Applicant: CAMBRIDGE ENTERPRISE LIMITED
    Inventors: Sabine Bahn, Emanuel Schwarz, Yishai Levin
  • BIOMARKERS
    Publication number: 20130017970
    Abstract: The invention relates to a method of diagnosing or monitoring schizophrenia or other psychotic disorder.
    Type: Application
    Filed: December 20, 2010
    Publication date: January 17, 2013
    Applicant: Psynova Neurotech Ltd.
    Inventors: Sabine Bahn, Yishai Levin, Emanuel Schwarz
  • BIOMARKERS FOR SCHIZOPHRENIA OR OTHER PSYCHOTIC DISORDERS
    Publication number: 20120251553
    Abstract: The invention relates to a method of diagnosing or monitoring schizophrenia or other psychotic disorder.
    Type: Application
    Filed: September 9, 2010
    Publication date: October 4, 2012
    Applicant: Psynova Neurotech Ltd.
    Inventors: Sabine Bahn, Yishai Levin
  • BIOMARKERS
    Publication number: 20120040852
    Abstract: The present invention relates to a method of diagnosing or monitoring schizophrenia or other psychotic disorders
    Type: Application
    Filed: October 8, 2009
    Publication date: February 16, 2012
    Applicant: Psynova Neurotech Ltd.
    Inventors: Yishai Levin, Lan Wang, Sabine Bahn
  • Methods and biomarkers for diagnosing and monitoring psychotic disorders
    Patent number: 7981684
    Abstract: A method of diagnosing or monitoring a psychotic disorder, or predisposition thereto, comprises measuring, in a sample taken from a subject, the level of a biomarker selected from clusterin precursor, inter ?-trypsin inhibitor, IgM, apolipoprotein A2 and ?2 H5 glycoprotein.
    Type: Grant
    Filed: January 21, 2008
    Date of Patent: July 19, 2011
    Assignee: Psynova Neurotech Limited
    Inventors: Yishai Levin, Sabine Bahn
  • METHODS AND BIOMARKERS FOR DIAGNOSING AND MONITORING PSYCHOTIC DISORDERS
    Publication number: 20110165554
    Abstract: A method of diagnosing or monitoring a psychotic disorder, or predisposition thereto, comprises measuring, in a sample taken from a subject, the levels of one or more peptide biomarkers listed herein.
    Type: Application
    Filed: December 18, 2008
    Publication date: July 7, 2011
    Applicants: Psynova Neurotech Limited, Cambridge Enterprise Limited
    Inventors: Yishai Levin, Sabine Bahn, Lan Wang, Emanuel Schwarz, George McAllister
  • METHODS AND BIOMARKERS FOR DIAGNOSING AND MONITORING PSYCHOTIC DISORDERS
    Publication number: 20100129919
    Abstract: A method of diagnosing or monitoring a psychotic disorder, or predisposition thereto, comprises measuring, in a sample taken from a subject, the level of a biomarker selected from clusterin precursor, inter ?-trypsin inhibitor, IgM, apolipoprotein A2 and ?2 H5 glycoprotein.
    Type: Application
    Filed: January 21, 2008
    Publication date: May 27, 2010
    Inventors: Yishai Levin, Sabine Bahn