Patents by Inventor Yixin Lin

Yixin Lin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Disruption of EGFR-SAR1 interaction for cancer treatment
    Patent number: 10663465
    Abstract: The present invention relates to the discovery that delivery of EGFR to cell surface requires EGFR-SAR1A binding. Thus, the invention provides a method for identifying inhibitors of EGFR-SAR1A binding, which can serve as therapeutic agents for treating conditions involving undesirable EGFR signaling. The invention also provides novel composition and its use that suppresses the specific binding between EGFR and SAR1A for the purpose of treating or preventing a condition involving undesired EGFR signaling.
    Type: Grant
    Filed: January 22, 2019
    Date of Patent: May 26, 2020
    Assignee: The Hong Kong University of Science and Technology
    Inventors: Yusong Guo, Pik Ki Lau, Yixin Lin
  • DISRUPTION OF EGFR-SAR1 INTERACTION FOR CANCER TREATMENT
    Publication number: 20190277844
    Abstract: The present invention relates to the discovery that delivery of EGFR to cell surface requires EGFR-SAR1A binding. Thus, the invention provides a method for identifying inhibitors of EGFR-SAR1A binding, which can serve as therapeutic agents for treating conditions involving undesirable EGFR signaling. The invention also provides novel composition and its use that suppresses the specific binding between EGFR and SAR1A for the purpose of treating or preventing a condition involving undesired EGFR signaling.
    Type: Application
    Filed: January 22, 2019
    Publication date: September 12, 2019
    Inventors: Yusong GUO, Pki Ki LAU, Yixin LIN
  • Detection of biomarkers and biomarker complexes
    Patent number: 8877516
    Abstract: The invention features methods and devices for the detection of biomarker complexes and their components and for the sequential detection of multiple epitopes of a biomarker. The invention also features methods for diagnosing disease and evaluating the efficacy of treatment of a subject with a disease.
    Type: Grant
    Filed: December 20, 2012
    Date of Patent: November 4, 2014
    Assignee: Axela, Inc.
    Inventors: Yixin Lin, Jean-François Houle
  • Detection of biomarkers and biomarker complexes
    Patent number: 8338189
    Abstract: The invention features methods and devices for the detection of biomarker complexes and their components and for the sequential detection of multiple epitopes of a biomarker. The invention also features methods for diagnosing disease and evaluating the efficacy of treatment of a subject with a disease.
    Type: Grant
    Filed: March 4, 2009
    Date of Patent: December 25, 2012
    Assignee: Axela Inc.
    Inventors: Yixin Lin, Jean-Francois Houle
  • DETECTION OF BIOMARKERS AND BIOMARKER COMPLEXES
    Publication number: 20090233268
    Abstract: The invention features methods and devices for the detection of biomarker complexes and their components and for the sequential detection of multiple epitopes of a biomarker. The invention also features methods for diagnosing disease and evaluating the efficacy of treatment of a subject with a disease.
    Type: Application
    Filed: March 4, 2009
    Publication date: September 17, 2009
    Applicant: Axela Inc.
    Inventors: Yixin Lin, Jean-Francois Houle