Abstract: A kit-of-parts for visualizing by a magnetic resonance imaging (MRI) technique including a functional magnetic resonance imaging (fMRI) technique, regions of a central nervous system of a patient having an implanted active implantable medical device (AIMD) is provided. The kit-of-parts is provided and includes: the AIMD, which can be used exposed to the electromagnetic conditions for MR-images acquisition, an external processing unit for controlling the AIMD, an optical communication lead for establishing a two-way optical communication between the AIMD and an external communication unit which is controlled by the external processing unit. A patient having an implanted AIMD can be treated in a conventional MR-device for imaging, e.g., a brain region. The other elements of the kit-of-parts allow controlling the functions of the AIMD and following any effects of a stimulation on the brain region thus imaged.

Abstract: An active implantable medical device (AIMD), for electrical stimulation of a tissue includes a light source, lodged in an encapsulation unit, for delivering optical energy pulses of optical power (Popt). A stimulation optical fibre for transferring optical energy from the light source of the encapsulation unit to the tissue coupling unit is also provided. The tissue coupling unit is configured for being coupled to a tissue to be electrically stimulated by electrodes (65) belonging to an electrical circuit. The PV-unit includes Us units arranged in series, each unit having Pp photovoltaic cells (PV-cells) arranged in parallel. Us and Pp, ?N, and Us×Pp=N=constant. The electrical circuit includes switches configured for varying the values of Us and alternatively or concomitantly, the light source is an addressable optical emitters array.

Abstract: An active implantable medical device (AIMD), for electrical stimulation of a tissue includes a light source, lodged in an encapsulation unit, for delivering optical energy pulses of optical power (Popt). A stimulation optical fibre for transferring optical energy from the light source of the encapsulation unit to the tissue coupling unit is also provided. The tissue coupling unit is configured for being coupled to a tissue to be electrically stimulated by electrodes (65) belonging to an electrical circuit. The PV-unit includes Us units arranged in series, each unit having Pp photovoltaic cells (PV-cells) arranged in parallel. Us and Pp, ?, and Us×Pp=N=constant. The electrical circuit includes switches configured for varying the values of Us and alternatively or concomitantly, the light source is an addressable optical emitters array.

Abstract: A kit-of-parts for visualizing by a magnetic resonance imaging (MRI) technique including a functional magnetic resonance imaging (fMRI) technique, regions of a central nervous system of a patient having an implanted active implantable medical device (AIMD) is provided. The kit-of-parts is provided and includes: the AIMD, which can be used exposed to the electromagnetic conditions for MR-images acquisition, an external processing unit for controlling the AIMD, an optical communication lead for establishing a two-way optical communication between the AIMD and an external communication unit which is controlled by the external processing unit. A patient having an implanted AIMD can be treated in a conventional MR-device for imaging, e.g., a brain region. The other elements of the kit-of-parts allow controlling the functions of the AIMD and following any effects of a stimulation on the brain region thus imaged.

Abstract: A kit of parts and method for the control of a delivery of an electric or electromagnetic pulse to a vagus nerve by an implanted stimulating device is provided. The kit of parts includes an implantable stimulating device (10) that includes a cuff electrode/optrode for being coupled to a vagus nerve (Vn) of a patient to be treated, and an encapsulation unit (50) suitable for being subcutaneously implanted at a location separated from the vagus nerve coupling unit (60), and enclosing an energy pulse generator (51s), for delivering electrical or optical energy pulses, and coupled to the cuff electrode/optrode by one or more electrical conductors (41e) and/or optical fibres (41f), an external controller device (100) of the kit includes laryngeal electrodes (161) suitable for being coupled to a laryngeal region (Lx) of a patient for measuring a laryngeal electrical activity at the laryngeal region, the laryngeal electrodes being coupled to an external control unit (150).