Abstract: The present disclosure improves the accuracy of blood flow assessment. According to one embodiment of the present invention, a blood flow assessment device has: a measurement part configured to measure skin temperatures at a plurality of locations on a face of a user; a calculation part configured to calculate a variation of the skin temperatures at the plurality of locations; and a blood flow assessment part configured to assess a blood flow of the user based on the variation.

Abstract: A catheter kit includes a catheter having an optical fiber, and a catheter accommodating tool which accommodates the catheter. The catheter accommodating tool has a tubular hoop, and a position adjustment mechanism provided at the hoop. The hoop has a hoop tip end portion at which a catheter tip end portion, from which laser light transmitted through the optical fiber is emitted, is disposed, and a hoop base end portion which is opposite to the hoop tip end portion. The position adjustment mechanism is provided at the hoop base end portion and changes a position of the catheter tip end portion with respect to the hoop tip end portion.

Abstract: A light output monitoring apparatus includes a light receiving unit, an attachment unit, an adapter, and a protective cap, and monitors a power of light output from a light emitting end of a catheter incorporating an optical fiber. The protective cap includes an insertion opening into which a part of the catheter of a predetermined range on the light emitting end side is removably inserted, includes a window portion for transmitting the light output from the light emitting end of the catheter, and is fixed in position by being inserted into a through-hole of the adapter. The adapter is fixed in position by being attached to the attachment unit.

Abstract: The present invention relates to a method for detecting an amyloid ? oligomer which includes a test sample and thioflavin T are brought into contact with each other, fluorescence of the thioflavin T is measured to obtain time-resolved fluorescence spectra, the time-resolved fluorescence spectrum of time period t1 to t2 and the time-resolved fluorescence spectrum of time period t3 to t4 are respectively normalized to obtain normalized spectra (t1<t2?t3<t4), and determination is made to confirm the presence or absence of an amyloid ? oligomer in the test sample on the basis of the two normalized spectra, and shifting of the normalized spectrum of time period t3 to t4 towards the low wavelength side in comparison to the normalized spectrum of time period t1 to t2 indicates the presence of an amyloid ? oligomer in the test sample.

Abstract: The present invention relates to a method for detecting an amyloid ? oligomer which includes a test sample and thioflavin T are brought into contact with each other, fluorescence of the thioflavin T is measured to obtain time-resolved fluorescence spectra, the time-resolved fluorescence spectrum of time period t1 to t2 and the time-resolved fluorescence spectrum of time period t3 to t4 are respectively normalized to obtain normalized spectra (t1<t2?t3<t4), and determination is made to confirm the presence or absence of an amyloid ? oligomer in the test sample on the basis of the two normalized spectra, and shifting of the normalized spectrum of time period t3 to t4 towards the low wavelength side in comparison to the normalized spectrum of time period t1 to t2 indicates the presence of an amyloid ? oligomer in the test sample.

Abstract: A light measurement device measures the intensity of laser light output from a catheter tip end portion of a catheter having a built-in optical fiber. The light measurement device includes a light receiving part which receives the laser light output from the catheter tip end portion and a mounting part which is disposed at a position facing the light receiving part. The mounting part defines a position of a tubular hoop, which accommodates the catheter, with respect to the light receiving part. In a state in which the position of the hoop is defined by the mounting part, the light measurement device obtains the intensity of the laser light by inputting the laser light to the light receiving part.

Abstract: A catheter kit includes a catheter having an optical fiber, and a catheter accommodating tool which accommodates the catheter. The catheter accommodating tool has a tubular hoop, and a protection cap which is provided to the hoop. The protection cap has a transmission window through which laser light L output from the catheter passes.

Abstract: The present invention relates to a method for purifying pure thioflavin T in having a step of preparing a thioflavin T solution in which crude thioflavin T is dissolved in a polar solvent, a step of bringing the thioflavin T solution into contact with a non-polar polymeric porous body, and a step of separating the thioflavin T solution after the contact from the non-polar polymeric porous body.

Abstract: A catheter kit includes a catheter having an optical fiber, and a catheter accommodating tool which accommodates the catheter. The catheter accommodating tool has a tubular hoop, and a protection cap which is provided to the hoop. The protection cap has a transmission window through which laser light L output from the catheter passes.

Abstract: A light measurement device measures the intensity of laser light output from a catheter tip end portion of a catheter having a built-in optical fiber. The light measurement device includes a light receiving part which receives the laser light output from the catheter tip end portion and a mounting part which is disposed at a position facing the light receiving part. The mounting part defines a position of a tubular hoop, which accommodates the catheter, with respect to the light receiving part. In a state in which the position of the hoop is defined by the mounting part, the light measurement device obtains the intensity of the laser light by inputting the laser light to the light receiving part.

Abstract: A catheter kit includes a catheter having an optical fiber, and a catheter accommodating tool which accommodates the catheter. The catheter accommodating tool has a tubular hoop, and a position adjustment mechanism provided at the hoop. The hoop has a hoop tip end portion at which a catheter tip end portion from which laser light transmitted through the optical fiber is emitted is disposed, and a hoop base end portion which is opposite to the hoop tip end portion. The position adjustment mechanism is provided at the hoop base end portion and changes a position of the catheter tip end portion with respect to the hoop tip end portion.

Abstract: A light output monitoring apparatus includes a light receiving unit, an attachment unit, an adapter, and a protective cap, and monitors a power of light output from a light emitting end of a catheter incorporating an optical fiber. The protective cap includes an insertion opening into which a part of the catheter of a predetermined range on the light emitting end side is removably inserted, includes a window portion for transmitting the light output from the light emitting end of the catheter, and is fixed in position by being inserted into a through-hole of the adapter. The adapter is fixed in position by being attached to the attachment unit.

Abstract: The present invention relates to a method for detecting an amyloid ? oligomer which includes a test sample and thioflavin T are brought into contact with each other, fluorescence of the thioflavin T is measured to obtain time-resolved fluorescence spectra, the time-resolved fluorescence spectrum of time period t1 to t2 and the time-resolved fluorescence spectrum of time period t3 to t4 are respectively normalized to obtain normalized spectra (t1<t2?t3 <t4), and determination is made to confirm the presence or absence of an amyloid ? oligomer in the test sample on the basis of the two normalized spectra, and shifting of the normalized spectrum of time period t3 to t4 towards the low wavelength side in comparison to the normalized spectrum of time period t1 to t2 indicates the presence of an amyloid ? oligomer in the test sample.

Abstract: The present invention relates to a method for purifying pure thioflavin T in having a step of preparing a thioflavin T solution in which crude thioflavin T is dissolved in a polar solvent, a step of bringing the thioflavin T solution into contact with a non-polar polymeric porous body, and a step of separating the thioflavin T solution after the contact from the non-polar polymeric porous body.