Abstract: An image processing device includes: one or more processors including hardware. The one or more processors are configured to: calculate, on a basis of a reference image acquired by capturing an image of a reference subject which has an optical characteristic that is equivalent to at least a part of a living body, image transformation parameters through congruence transformation that transforms a coordinate corresponding to a color of target region included in the reference image defined in a color space into a coordinate corresponding to an achromatic color in the color space; and perform, in the color space on a basis of the calculated image transformation parameters, the congruence transformation of colors of a color image acquired by capturing an image of the living body, the color image being constituted by at least two monochromatic image corresponding to different illumination having different center wavelengths.

Abstract: An endoscope apparatus including: a light source configured to emit illumination light including light in a first wavelength band included in a blue wavelength band, light in a first narrowband included in a green wavelength band, and light in a second narrowband having a same light absorption coefficient of hemoglobin as that of the light in the first narrowband; an imager configured to acquire a first image of an object in the first wavelength band, a first narrowband image of the object in the first narrowband, and a second narrowband image of the object in the second narrowband; and a processor including hardware. The processor is configured to implement acquiring scattering characteristics information based on a comparison result between the first narrowband image and the second narrowband image, and generating an observation image using the first image, the first narrowband image, and the scattering characteristics information.

Abstract: An observation system includes a processor. The processor manages a plurality of images acquired in time series with respect to a biological sample which is being cultured, records a first comment and a first region of interest (RoI) in a storage device in association with the images based on user's instructions, and records a second comment and a second ROI in the storage device in association with the first comment based on user's instructions.

Abstract: An observation apparatus including: a top plate on which a container in which a specimen is accommodated can be placed, and through which illumination light can pass; a light source that emits the illumination light upward from below the specimen; an objective lens that focuses, below the specimen and the top plate, transmitted light which is the illumination light that has passed through the specimen from thereabove and that has passed through the top plate; and a camera that captures the transmitted light, wherein the light source emits the illumination light toward an area above the specimen from outside the objective lens in a radial direction, and the top plate is provided with a mark that specifies a viewing-field area of the camera.

Abstract: An image reproducing device includes one or more processors. The processor acquires image group data including a plurality of images and tag information on at least one tag. The images relate to a biological sample along time series. The tag information relates to an operation on the biological sample and is associated with at least part of the images. The processor selects from the plurality of images using the tag information, images to be reproduced along the time series as reproduction selected images. The processor outputs to a display, data relating to the images for the reproduction selected images to be reproduced along time series.

Abstract: An observation apparatus including: a light-source that emits illumination light and excitation light upward from below a specimen; and an image-capturing optical system having an objective lens that focuses, below the specimen, transmitted light, which is the illumination light that is emitted from the light-source, that is reflected above the specimen, and that has passed through the specimen, and fluorescence that is generated in the specimen that has been irradiated with the excitation light emitted from the light-source, wherein the light-source is disposed radially outside the objective lens.

Abstract: A cell observation system includes an imaging element that acquires images of the inside of a culture container in which cells are cultured, the imaging element acquiring the images over time; a computer configured to: quantitatively analyze a culture state of the cells cultured in the culture container on the basis of each of the images acquired by the imaging element; and statistically analyze the quantitatively analyzed data; and a display that displays statistical analysis results in the culture container within a plurality of subculture periods obtained by the computer in a manner allowing comparison of the statistical analysis results.

Abstract: An image processing device includes: one or more processors including hardware. The one or more processors are configured to: calculate, on a basis of a reference image acquired by capturing an image of a reference subject which has an optical characteristic that is equivalent to at least a part of a living body, image transformation parameters through congruence transformation that transforms a coordinate corresponding to a color of target region included in the reference image defined in a color space into a coordinate corresponding to an achromatic color in the color space; and perform, in the color space on a basis of the calculated image transformation parameters, the congruence transformation of colors of a color image acquired by capturing an image of the living body, the color image being constituted by at least two monochromatic image corresponding to different illumination having different center wavelengths.

Abstract: An endoscope apparatus including: a light source configured to emit illumination light including light in a first wavelength band included in a blue wavelength band, light in a first narrowband included in a green wavelength band, and light in a second narrowband having a same light absorption coefficient of hemoglobin as that of the light in the first narrowband; an imager configured to acquire a first image of an object in the first wavelength band, a first narrowband image of the object in the first narrowband, and a second narrowband image of the object in the second narrowband; and a processor including hardware. The processor is configured to implement acquiring scattering characteristics information based on a comparison result between the first narrowband image and the second narrowband image, and generating an observation image using the first image, the first narrowband image, and the scattering characteristics information.

Abstract: A control device for an ablation treatment tool includes: a target-value storage unit that stores a target value for the total treatment area; an energy-source output unit that outputs, to the ablation treatment tool, an energy source for performing ablation treatment; an area calculation unit that calculates the total treatment area of the ileal mucosa on which the ablation treatment has been performed; and a control unit that controls termination of the ablation treatment performed by the ablation treatment tool. The control unit notifies an operator of the termination of the ablation treatment or stops the output of the energy source from the energy-source output unit when the calculated total treatment area of the ileal mucosa becomes equal to or greater than the target value.

Abstract: An observation system includes a processor. The processor manages a plurality of images acquired in time series with respect to a biological sample which is being cultured, records a first comment and a first region of interest (RoI) in a storage device in association with the images based on user's instructions, and records a second comment and a second ROI in the storage device in association with the first comment based on user's instructions.

Abstract: A quantitative evaluation apparatus of the present invention includes: a counter that counts the numbers of cells or densities of cells contained in individual images of a plurality of image-capturing regions in a culturing vessel for culturing the cells; an evaluation-value calculating portion that calculates an evaluation value related to variation in the distribution of the cells in the culturing vessel on the basis of the numbers of the cells or the densities of cells counted by means of the counter in each of the images; a determining portion that determines whether or not the evaluation value calculated by the evaluation-value calculating portion is in a range of a prescribed threshold; and a display that displays determination result determined by the determining portion.

Abstract: An image reproducing device includes one or more processors. The processor acquires image group data including a plurality of images and tag information on at least one tag. The images relate to a biological sample along time series. The tag information relates to an operation on the biological sample and is associated with at least part of the images. The processor selects from the plurality of images using the tag information, images to be reproduced along the time series as reproduction selected images. The processor outputs to a display, data relating to the images for the reproduction selected images to be reproduced along time series.

Abstract: Provided is an observation apparatus including: a housing that has, in a top face thereof, a transmission window on which a container accommodating cells can be placed and through which light can pass; a camera portion that is accommodated in the housing and that captures observation light coming from the cells irradiated with illumination light emitted from an illumination portion and entering the housing by passing through a bottom face of the container and the transmission window of the housing; and a housing-interior heating portion that is accommodated in the housing and that heats the cells.

Abstract: A cell observation system includes an imaging element that acquires images of the inside of a culture container in which cells are cultured, the imaging element acquiring the images over time; a computer configured to: quantitatively analyze a culture state of the cells cultured in the culture container on the basis of each of the images acquired by the imaging element; and statistically analyze the quantitatively analyzed data; and a display that displays statistical analysis results in the culture container within a plurality of subculture periods obtained by the computer in a manner allowing comparison of the statistical analysis results.

Abstract: For the purpose of counting the number of cells within a culture container readily and accurately, a cell analysis device includes a cell-image acquiring unit that acquires an image of cells within a culture container in which the cells are cultured, a usability determining unit that determines whether or not the image acquired by the cell-image acquiring unit is usable, a number-of-cells counting unit that counts the number of cells within the image determined as being usable by the usability determining unit, and a number-of-cells calculating unit that calculates the number of cells within the culture container based on the number of cells counted by the number-of-cells counting unit.

Abstract: A cell analysis apparatus including: a cell image acquisition unit that acquires an image of cells in a culture vessel in which cells are cultured; a smoothing processing unit that smooths luminance values in the image acquired by the cell image acquisition unit; a minimum-value detecting unit that detects minimum values of the luminance values smoothed by the smoothing processing unit; a smallest-minimum-value extracting unit that extracts smallest minimum values which are the smallest in regions according to the sizes of the cells, from the minimum values detected by the minimum-value detecting unit; a counting unit that counts the number of smallest minimum values extracted by the smallest-minimum-value extracting unit; and a cell-count calculating unit that calculates the number of cells in the culture vessel on the basis of the number of smallest minimum values counted by the counting unit.

Abstract: An observation apparatus including: a light-source that emits illumination light and excitation light upward from below a specimen; and an image-capturing optical system having an objective lens that focuses, below the specimen, transmitted light, which is the illumination light that is emitted from the light-source, that is reflected above the specimen, and that has passed through the specimen, and fluorescence that is generated in the specimen that has been irradiated with the excitation light emitted from the light-source, wherein the light-source is disposed radially outside the objective lens.

Abstract: An observation device includes: a housing having, in a top surface, a glass window on which a vessel accommodating samples is placed and through which illumination light is transmitted; and an image acquisition unit accommodated in the housing and configured to capture transmitted light obtained after illumination light is transmitted through the samples from above, is transmitted through the glass window, and enters the housing.

Abstract: An observation apparatus including: a top plate on which a container in which a specimen is accommodated can be placed, and through which illumination light can pass; a light source that emits the illumination light upward from below the specimen; an objective lens that focuses, below the specimen and the top plate, transmitted light which is the illumination light that has passed through the specimen from thereabove and that has passed through the top plate; and a camera that captures the transmitted light, wherein the light source emits the illumination light toward an area above the specimen from outside the objective lens in a radial direction, and the top plate is provided with a mark that specifies a viewing-field area of the camera.