Abstract: A blood state evaluation device, blood state evaluation system, blood state evaluation method, and program that enable evaluation of the risk of thrombosis easily and precisely is provided. An electrical characteristic of blood being an evaluation target is chronologically measured in two or more frequencies or two or more frequency bands. On the basis of chronological change data of the measured electrical characteristic of the blood, a state of blood is evaluated.

Abstract: A flow channel device includes an inflow unit into which a transfer fluid that transfers particles is caused to flow, a first outflow unit including an inflow port into which a part of the transfer fluid caused to flow from the inflow unit is caused to flow, a holding unit that is connected to the inflow port and holds particles, and a particle outflow port from which the particles held in the holding unit are caused to flow out to a predetermined flow channel area by the transfer fluid caused to flow from the inflow port, and a second outflow unit including a peripheral outflow channel through which another part of the transfer fluid caused to flow from the inflow unit is caused to flow out to a peripheral flow channel area that surrounds the predetermined flow channel area, the peripheral outflow channel surrounding at least the particle outflow port.

Abstract: A sample cartridge for measuring the electrical characteristics of a liquid sample, which is made by forming an insulating material into a tubular body and is capable of holding the liquid sample in a region that is constituted by the surfaces of electrodes that are respectively inserted from openings of both ends into an inner cavity and the surface of the inner cavity, and in which a narrowing portion located between two facing electrodes and having a narrowed inner cavity is provided in the region.

Abstract: There is provided a method of producing a fluid channel device including laminating a plurality of polyimide films including at least one polyimide film having a port and at least one polyimide film having a channel, the polyimide films including at least one thermoplastic polyimide film; and adhering a plurality of the polyimide films by applying heat such that the ports are communicated with the channels. There is also provided the flow channel device produced by the method.

Abstract: [Solving Means] A flow channel device includes a vessel layer and a flow channel layer. The vessel layer includes an injection vessel section into which a fluid including a sample is injected and a collection vessel section that collects the fluid. The flow channel layer includes a flow channel connected to the injection vessel section and the collection vessel section and is bonded to the vessel layer.

Abstract: A cell sorting apparatus includes a flow channel through which fluid including cells flows, an electric-field application section capable of applying an electric field having a gradient in a direction different from the flowing direction of the fluid at a first position on the flow channel in accordance with a cell sorting signal requesting an operation to sort the cells, and a flow splitting section configured to split the cells changing their flowing directions due to a dielectrophoretic force caused by application of the electric field at a second position on the downstream side of the first position on the flow channel.

Abstract: A measurement apparatus includes a generation section and a measurement section and performs a predetermined measurement using a flow channel device including a narrow channel through which particles pass by a flow of a fluid and a measurement electrode section provided in the vicinity of the narrow channel. The generation section generates, in the measurement electrode section, an AC voltage that is higher than a characteristic frequency defined by a conductance of the fluid including the particles in the narrow channel and an electrical double layer capacitance formed by the measurement electrode section and has a frequency range indicating a conductance corresponding to a size of the particles. The measurement section measures, while the AC voltage is applied to the measurement electrode section, an electrical amount including at least the conductance obtained when the particles pass through the narrow channel.

Abstract: There is provided a blood condition analyzing device including an erythrocyte quantitative evaluation unit configured to evaluate a hematocrit value and/or a hemoglobin amount on the basis of an electrical characteristic of a blood sample at a frequency of 2 to 25 MHz.

Abstract: There is provided a microparticle analysis apparatus including a sample channel configured to receive liquid containing a plurality of microparticles, a first pair of electrodes configured to form an alternating electric field in at least a part of the sample channel, a measuring part configured to measure impedance between the first pair of electrodes, an analyzing part configured to calculate property values of the microparticles from the impedance measured in the measuring part, and a determining part configured to determine whether data of the impedance measured in the measuring part is derived from the microparticles.

Abstract: The present disclosure provides an apparatus for sample introduction including a flow channel, a sample inlet, a metering unit, a separating unit, cell dischargers and, and a pressure controlling unit. The sample inlet is given a sample fluid such as blood. The sample inlet has a constricting hole that communicates with the flow channel for passage of a carrier fluid. The constricting hole has a diameter large enough for passage of a single cell contained in the sample fluid. The sample fluid is introduced into the flow channel through the constricting hole, and the cells in the sample fluid pass one by one through the constricting hole. The constricting hole does not exist inside the flow channel for passage of the carrier fluid, so that the diameter of the constricting hole does not affect the flow rate of the carrier fluid passing through the flow channel.

Abstract: There is provided an electrical characteristic measuring device including a rotating mechanism that rotates a sample container to be filled with blood to be measured, to any angle, and a measurement unit that applies a voltage between a pair of electrodes installed in the sample container, and chronologically measures electrical characteristics of the blood.

Abstract: A cell sorting apparatus includes a flow channel through which fluid including cells flows, an electric-field application section capable of applying an electric field having a gradient in a direction different from the flowing direction of the fluid at a first position on the flow channel in accordance with a cell sorting signal requesting an operation to sort the cells, and a flow splitting section configured to split the cells changing their flowing directions due to a dielectrophoretic force caused by application of the electric field at a second position on the downstream side of the first position on the flow channel.

Abstract: There is provided a plate-like member for pipette tips including a pipette tip insertion hole disposed on a first plane, one or a plurality of communicating holes that is disposed on a second plane as a back face of the first plane and that communicates with the pipette tip insertion hole, and one or a plurality of flow passages through which a liquid discharged from a pipette tip inserted into the pipette tip insertion hole flows from the second plane side to the first plane side.

Abstract: There is provided an electrical measuring cartridge of a biological sample, the electrical measuring cartridge including at least a plurality of biological sample holding sections each being configured to contain the biological sample, and a pair of electrical conductive sections fixed to each of the biological sample holding sections.

Abstract: Provided is a cell determination device including a classification unit configured to classify individual cells based on one of a relaxation strength, a relaxation frequency, and low-frequency conductance obtained from a complex dielectric constant spectrum of the cells.

Abstract: A blood coagulation analysis device and method in which information relating to the coagulability of blood is evaluated based on a change generated in a permittivity measured in a coagulation process of the blood due to addition of a substance that activates or inactivates platelets to the blood.

Abstract: There is provided a method of producing a fluid channel device including laminating a plurality of polyimide films including at least one polyimide film having a port and at least one polyimide film having a channel, the polyimide films including at least one thermoplastic polyimide film; and adhering a plurality of the polyimide films by applying heat such that the ports are communicated with the channels. There is also provided the flow channel device produced by the method.

Abstract: Provided is a sorting apparatus including: a flow channel device including a flow channel through which a fluid including particles flows and an operation electrode portion that causes a dielectrophoretic force to act on the particles in the flow channel; and a controller configured to detect characteristics of the particles flowing through the flow channel, generate a voltage signal by a pulse modulation using a square pulse based on the detected characteristics of the particles, and output the voltage signal to the operation electrode portion.