Abstract: A method of preparing crystals of a glucosylmoranoline formula (III) ##STR1## wherein R is hydrogen or lower alkyl by fractional cyrstallizatin using a polar solvent and an arylsulfonic acid.

Abstract: 2-amino-2-deoxy-D-mannitol is produced from a microorganism strain of the genus Streptomyces or a mutant strain thereof in improved yields and purity.

Abstract: Compounds of formula I are useful in the prophylaxis or treatment of hyperglycemic symptoms ##STR1## wherein R is alkyl substituted by one or more hydroxy.

Abstract: A compound of formula (I) ##STR1## wherein: B is a divalent substituted or unsubstituted, cyclic or acyclic, saturated or unsaturated hydrocarbon group;A is a linking group selected from the group consisting of --O--, --S--, --N(H)--, --N(R)--, --C(O)-- and combinations of two or more thereof or A is a direct bond; andR is a monovalent substituted or unsubstituted, cyclic or acyclic, saturated or unsaturated hydrocarbon group, a monovalent substituted or unsubstituted aromatic hydrocarbon group, or a monovalent substituted or unsubstituted heterocyclyl provided that B--A--R may not represent hydrogen, lower alkyl, or a monovalent cyclic or acyclic hydrocarbon group having one or more hydroxyl groups, which is useful for inhibiting an increase in blood glucose in humans and for the treatment of diabetes mellitus.

Abstract: A method of preparing a molecular compound of glucosylmoranoline of the formula I ##STR1## with methanol, which comprises stirring an aqueous solution comprising (I) and other moranoline derivatives with methanol, whereupon crystals of the molecular compound of (I) with methanol are formed.

Abstract: A compound of the formula (I): ##STR1## in which: is a single bond or a double bond,X is hydrogen or hydroxy,n is 0 or 1,Z is ##STR2## when in ring B is a double bond, and, when in ring B is a single bond, Z is wherein W is hydrogen, lower acyl, unsubstituted arylcarbonyl, lower alkyl or substituted arylcarbonyl.These compounds are useful as platelet aggregation inhibitors.

Abstract: Compounds of the formula (I): ##STR1## and pharmaceutically acceptable salts thereof wherein R.sup.1 is hydrogen, alkyl of 1 to 10 carbon atoms or acyl of 1 to 6 carbon atoms; R.sup.2 is hydrogen or halo; R.sup.3 is hydrogen, alkyl of 1 to 6 carbon atoms or acyl of 1 to 6 carbon atoms; R.sup.4 is hydrogen or alkyl of 1 to 6 carbon atoms; R.sup.5 is hydrogen or acyl of 1 to 6 carbon atoms; X is CONH.sub.2, hydroxyalkyl of 1 to 4 carbon atoms or COOR.sup.6 wherein R.sup.6 is hydrogen or alkyl of 1 to 4 carbon atoms; and Y is CONH.sub.2, hydroxyalkyl of 1 to 4 carbon atoms or COOR.sup.7 wherein R.sup.7 is hydrogen, alkyl of 1 to 10 carbon atoms or benzyl are useful for inhibiting the activity of amino-peptidase B, exhibit immunomodulating action against living organisms and exhibit anti-inflammatory activity.

Abstract: Bisglucosyl moranoline of the formula (I) ##STR1## is useful in inhibiting increase of blood sugar in sugar-loaded animals and humans, and particularly for treatment of diabetes mellitus.

Abstract: Moranoline, or 2-hydroxymethyl-3,4,5-trihydroxy piperidine, is prepared by directly reducing an actinomycetes culture solution containing nojirimycin, followed by isolation, as for example, through the utilization of an ion exchange resin. The corresponding N-methyl derivative can be obtained through the addition of formaldehyde to the culture solution prior to the reduction.

Abstract: Moranolines are produced which are useful for controlling blood sugar levels.

Abstract: 2-Hydroxymethyl-3,4,5-trihydroxy piperidine, or moranoline, is prepared by culturing a moranoline-producing strain of microorganism of the genus Streptomyces in an appropriate culture medium and thereafter isolating moranoline from the culture medium.