Abstract: An object detection method and apparatus include obtaining a point cloud of a scene that includes location information of points. The point cloud is mapped to a 3D voxel representation. A convolution operation is performed on the feature information of the 3D voxel to obtain a convolution feature set and initial positioning information of a candidate object region is determined based on the convolution feature set. A target point is located in the candidate object region in the point cloud is determined and the initial positioning information of the candidate object region is adjusted based on the location information and target convolution feature information of the target point. Positioning information of a target object region is obtained to improve object detection accuracy.

Abstract: A control method for a wireless smart wearable device is performed by a terminal device and includes: receiving a control instruction for the wireless smart wearable device from a preset control interface of the terminal device; determining a target device connected with the wireless smart wearable device; and transmitting, according to the control instruction, corresponding control information to the target device, so as to instruct the target device to control the wireless smart wearable device according to the control information.

Abstract: A connection method for a wireless smart wearable device is performed by a terminal device, and includes: receiving a connection switching instruction of the wireless smart wearable device from a preset control interface of the terminal device; determining a target device according to the connection switching instruction; and instructing, according to a preset parameter of the wireless smart wearable device, the target device to be connected with the wireless smart wearable device according to the preset parameter.

Abstract: Disclosed are methods of isolating paired T cell receptor (TCR) alpha and beta chain sequences, or an antigen-binding portion thereof. Also disclosed are methods of automatically identifying the TCR alpha and beta chain V segment sequences and CDR3 sequences of a TCR having antigenic specificity for a mutated amino acid sequence encoded by a cancer-specific mutation. Methods of preparing a population of cells that express paired TCR alpha and beta chain sequences, or an antigen-binding portion thereof, are also disclosed. Isolated pairs of TCR alpha and beta chain sequences and isolated populations of cells prepared by the methods are also disclosed.

Abstract: Disclosed is an isolated or purified T cell receptor (TCR) having antigenic specificity for mutated Kirsten rat sarcoma viral oncogene homolog (KRAS) presented in the context of an HLA-Cw*0802 molecule. Related polypeptides and proteins, as well as related nucleic acids, recombinant expression vectors, host cells, populations of cells, and pharmaceutical compositions are also provided. Also disclosed are methods of detecting the presence of cancer in a mammal and methods of treating or preventing cancer in a mammal.

Abstract: Provided is a method for preparing a hard carbon anode of a lithium/sodium ion battery by biochar, which includes the following steps: S1 biochar pretreatment, S2, preparing a precursor material and S3 pyrolysis carbonization, by a modification of the biochar, setting carbonization temperature and carbonization time, and controlling a cooling rate, so that the obtained biochar generates amorphous carbon after carbonization with low graphitization degree, few surface defects, larger charge-discharge specific capacity, and stable performance in the cycle charging and discharging process; at the same time, the process of the application is relatively simple, and a special complex process is reduced; the present method is suitable for a large-scale industrial production without special adjustment or control of a morphology; and the product performance is relatively good and thus has certain competitive advantages.

Abstract: The present invention discloses a quantum-dot film, wherein the quantum-dot film comprises a binder and a plurality of quantum dots dispersed in the binder, wherein the plurality of quantum dots are capable of being water-resistant and oxygen-resistant.

Abstract: An adjustable platform for installing a wind turbine generator comprises an adjustable platform shell, the adjustable platform shell is installed on a hull, pile legs are connected vertically in the adjustable platform shell in a sliding way, a plurality of adjusting jacks are arranged on the pile legs, an electric plug-in component is arranged in the adjustable platform shell and used for fitting with the adjusting jacks. The fitting of electric plug-in component with the adjusting jacks of the pile legs replaces the bolted connection between the installation platform and the pile legs, and the electric power is used to replace the manual operation, solving the technical problems in the prior art that bolted connection is required between the installation platform and the pile legs, bolts are required to be removed manually before the pile legs sink, and the labor cost is greatly consumed.

Abstract: A method for preparing a nitrogen-containing heterocyclic compound and a derivative thereof by an enzymatic-chemical cascade method, comprising: reacting an alcohol, an amine, an alcohol dehydrogenase, a flavin molecule and a coenzyme in a solvent to obtain the nitrogen-containing heterocyclic compound and the derivative thereof; compared with the prior art, the method is a green and economical enzymatic-chemical cascade method, and is used for synthesizing nitrogen-containing heterocyclic compounds and derivatives thereof; compared with a common toxic chemical catalyst, the alcohol dehydrogenase is selected as a catalyst in the method, which has the characteristics of high substrate specificity, no pollution, high catalytic efficiency, no toxic solvents and simple post-treatment.

Abstract: An improved device for solid phase microextraction, the device including a plastic substrate, a pre-coating layer on the plastic substrate, and an SPME coating on the precoating layer. SPME coatings are typically incompatible with plastic substrates due to differences between the surface energies of the substrate and the coating, leading to uneven coating and poor adhesion. The addition of the precoating layer provides increased evenness and stronger adhesion of the SPME coating to the plastic substrate. Also provided are method of coating an SPME coating on a plastic substrate, the method including the step of precoating the plastic substrate to provide a precoated substrate and then coating the precoated substrate with an SPME coating, wherein precoating provides improved coating evenness and adhesion of the SPME coating to the plastic substrate.

Abstract: A composite optical film comprises: a first substrate; a plurality of reversed prisms disposed on a bottom surface of the first substrate; and a first diffusion film disposed over a top surface of the first substrate.

Abstract: Disclosed herein are compositions and methods for treating a subject having an itch-related disorder, such as dermatological disorders or systemic disorders comprising itch. The methods may include determining the level of a biomarker in a biological sample from the subject. The biomarker may be selected from TRPV4 expression, lysophosphatidylcholine, and miRNA-146a expression, or a combination thereof. The subject may be identified as having the itch-related disorder when the level of the biomarker is greater in a sample from the subject than in a control. An anti-pruritic therapy may be administered to treat the subject having the itch-related disorder.

Abstract: Improved methods for drying for bio-compatible solid phase microextraction (BioSPME) coatings yielding coatings with highly consistent extraction efficiency and biocompatibility. The methods, adapted to flow-through drying systems involve determining relative humidity in and around the drying system, determining a drying temperature range based on the relative humidity, and maintaining the drying temperature within the determined range while drying the coating.

Abstract: A system for additively manufacturing a build part. The system includes a build platform configured for disposition within a resin tank, and a light source configured to cure a layer of resin. The layer of resin is disposed adjacent to a pre-cure build surface of the build part. The system also includes a constrained surface located between the build platform and the light source and configured to form a boundary for the layer of resin disposed between the constrained surface and the pre-cure build surface. The constrained surface is configured to vibrate to reduce a separation force required to separate the constrained surface from a post-cure build surface of the build part. The system also includes a vibratory source configured to vibrate the constrained surface.

Abstract: Provided are a method, an apparatus and a system for implementing carrier grade network address translation, an electronic device, and a computer-readable storage medium. The method includes: transmitting a first request to a control plane of a forwarding and control separated broadband access system, where the first request is used for applying to the control plane for a public network address range; receiving a first response returned by the control plane, where the first response includes allocated public network address range information; receiving a public network address allocated to a user by the control plane according to the public network address range information; receiving a private network address allocated to the user by the control plane; and performing, according to the public network address and the private network address, public and private network address translation on received service traffic of the user.

Abstract: The present disclosure relates to a method for recycling a taurine mother liquor, which includes: adding a base to the taurine mother liquor, heating to a first temperature, carrying out a hydrolysis reaction, removing ammonia produced, and evaporating and concentrating the ammonia-removed solution to obtain an alkali metal hydroxyethyl sulfonate solution. When applying the method provided by the present disclosure for the recycling of the taurine mother liquor, the taurine mother liquor can be further converted into the alkali metal hydroxyethyl sulfonate solution, impurities are removed from the obtained alkali metal hydroxyethyl sulfonate solution, the impurity-removed alkali metal hydroxyethyl sulfonate solution is concentrated and crystallized, and the alkali metal hydroxyethyl sulfonate is separated out.

Abstract: Disclosed is a high-efficiency cyclic preparation method for a columnar taurine finished product, including: preparing an aqueous taurine solution with a certain concentration; introducing the aqueous taurine solution into a basic resin for treatment to remove an alkali metal isethionate and an isethionic acid derivative; monitoring an effluent liquid at an outlet of the basic resin and collecting the effluent liquid that is monitored to be qualified; and crystallizing taurine of the collected effluent liquid to obtain a taurine crystal. The method of the present disclosure has the advantages of process innovation, and high efficiency, and the obtained taurine crystal has the advantages of good quality, good fluidity, no caking, low production cost and high efficiency, and has good prospects for industrial production.

Abstract: Disclosed is an isolated or purified T cell receptor (TCR) having antigenic specificity for mutated Kirsten rat sarcoma viral oncogene homolog (KRAS) presented in the context of an HLA-Cw*0802 molecule. Related polypeptides and proteins, as well as related nucleic acids, recombinant expression vectors, host cells, populations of cells, and pharmaceutical compositions are also provided. Also disclosed are methods of detecting the presence of cancer in a mammal and methods of treating or preventing cancer in a mammal.

Abstract: The present disclosure provides a resin composition, an adhesive-dropping material, an adhesive-pressing material, and a preparation method and application thereof. The resin composition comprises the following components: an ester-based prepolymer; a reactive diluent; and a photoinitiator; wherein the addition amount of the ester-based prepolymer is 60 to 80 parts by weight, the addition amount of the reactive diluent is 15 to 30 parts by weight, and the addition amount of the photoinitiator is 1 to 5 parts by weight, based on the part by weight. The artificial nail prepared by using the resin composition, the adhesive-dropping material, and the adhesive-pressing material according to the present disclosure has high mimicry. When in use, the artificial nail which is not completely hardened may be attached to the surface of the real nail and then hardened by UV light, so that the artificial nail is more conformable.