Abstract: A method, device and system for calculating a microcirculation indicator are provided. A method includes: injecting a vasodilator and subjecting a blood vessel to be measured to coronary angiography; selecting at least one angiographic image of a first body position when the blood vessel to be measured is in a resting state and an angiographic image of a second body position when the blood vessel to be measured is in a dilated state; obtaining a three-dimensional coronary artery vascular model by three-dimensional modeling; injecting a contrast agent, and obtaining time T1 taken for the contrast agent flowing from an inlet to an outlet of the segment of blood vessel and time T2 taken for the contrast agent flowing from an inlet to an outlet of the segment of blood vessel; obtaining the microcirculation indicator.

Abstract: The present disclosure is applicable to the technical field of metering and distributing of an adhesive dispensing machine, and provides a machine learning-based flexible intelligent adhesive dispensing method.

Abstract: A method, an apparatus and a system for conveniently measuring coronary artery vascular evaluation parameters are provided by the disclosure.

Abstract: A simplified method, an apparatus and a system for measuring coronary artery vascular evaluation parameters are provided.

Abstract: A method and system of predicting or estimating an adherence score representing a subject's adherence to a medication dosage scheme. A subject-reported adherence score is upwardly revised based on application usage information of an application used by the subject to report their adherence. A prediction model may be used to adjust the subject-reported adherence score based on the application usage information.

Abstract: A method, device and system for calculating a microcirculation indicator are provided. A method includes: injecting a vasodilator and subjecting a blood vessel to be measured to coronary angiography; selecting at least one angiographic image of a first body position when the blood vessel to be measured is in a resting state and an angiographic image of a second body position when the blood vessel to be measured is in a dilated state; obtaining a three-dimensional coronary artery vascular model by three-dimensional modeling; injecting a contrast agent, and obtaining time T1 taken for the contrast agent flowing from an inlet to an outlet of the segment of blood vessel and time T2 taken for the contrast agent flowing from an inlet to an outlet of the segment of blood vessel; obtaining the microcirculation indicator.

Abstract: A mitral valve replacement device is adapted to be deployed at a mitral valve position in a human heart. The device has an atrial flange defining an atrial end of the device, a ventricular portion defining a ventricular end of the device, the ventricular portion having a height ranging between 2 mm to 15 mm, and an annulus support that is positioned between the atrial flange and the ventricular portion. The annulus support includes a ring of anchors extending radially therefrom, with an annular clipping space defined between the atrial flange and the ring of anchors. A plurality of leaflet holders positioned at the atrial end of the atrial flange, and a plurality of valve leaflets secured to the leaflet holders, and positioned inside the atrial flange at a location above the native annulus.

Abstract: Presented are concepts for providing subject-specific information. One such concept comprises obtaining a first knowledge model, the first knowledge model comprising a plurality of clinical data elements for a population of subjects and relationship information representing one or more relationships between the clinical data elements. Also obtained is historical data relating to a sub-population of the population of subjects, the historical data relating to previously-obtained clinical data elements and relationship information for the sub-population. A second knowledge model is generated based on the first knowledge model and the historical data. A subject-specific model is generated based on the second knowledge model and subject-specific data relating to a subject.

Abstract: A mitral valve replacement device is adapted to be deployed at a mitral valve position in a human heart. The device has an atrial flange defining an atrial end of the device, a ventricular portion defining a ventricular end of the device, the ventricular portion having a height ranging between 2 mm to 15 mm, and an annulus support that is positioned between the atrial flange and the ventricular portion. The annulus support includes a ring of anchors extending radially therefrom, with an annular clipping space defined between the atrial flange and the ring of anchors. A plurality of leaflet holders positioned at the atrial end of the atrial flange, and a plurality of valve leaflets secured to the leaflet holders, and positioned inside the atrial flange at a location above the native annulus.

Abstract: A mitral valve replacement device is adapted to be deployed at a mitral valve position in a human heart. The device has an atrial flange defining an atrial end of the device, a ventricular portion defining a ventricular end of the device, the ventricular portion having a height ranging between 2 mm to 15 mm, and an annulus support that is positioned between the atrial flange and the ventricular portion. The annulus support includes a ring of anchors extending radially therefrom, with an annular clipping space defined between the atrial flange and the ring of anchors. A plurality of leaflet holders positioned at the atrial end of the atrial flange, and a plurality of valve leaflets secured to the leaflet holders, and positioned inside the atrial flange at a location above the native annulus.

Abstract: A mitral valve replacement device is adapted to be deployed at a mitral valve position in a human heart. The device has an atrial flange defining an atrial end of the device, a ventricular portion defining a ventricular end of the device, the ventricular portion having a height ranging between 2 mm to 15 mm, and an annulus support that is positioned between the atrial flange and the ventricular portion. The annulus support includes a ring of anchors extending radially therefrom, with an annular clipping space defined between the atrial flange and the ring of anchors. A plurality of leaflet holders positioned at the atrial end of the atrial flange, and a plurality of valve leaflets secured to the leaflet holders, and positioned inside the atrial flange at a location above the native annulus.

Abstract: A mitral valve replacement device is adapted to be deployed at a mitral valve position in a human heart. The device has an atrial flange defining an atrial end of the device, a valve body defining a ventricular end of the device, and an annulus support that connects the atrial flange and the valve body, the annulus support including a ring of tabs extending radially therefrom and adapted to engage the native mitral annulus and/or the native leaflet(s) of the human heart. The atrial flange can be seated in the atrium above the native mitral valve annulus in a human heart, and the ring of tabs can engage the native mitral annulus in a manner where the atrial flange and tabs provide a clipping effect to secure the mitral valve replacement device at the native mitral valve position.

Abstract: A mitral valve replacement device is adapted to be deployed at a mitral valve position in a human heart. The device has an atrial flange defining an atrial end of the device, a valve body defining a ventricular end of the device, and an annulus support that connects the atrial flange and the valve body, the annulus support including a ring of tabs extending radially therefrom and adapted to engage the native mitral annulus and/or the native leaflet(s) of the human heart.