Abstract: The present invention relates to a method for manufacturing a bone graft material using 3D printing of a DLP system. The method includes (1) dispersing a powder material including calcium phosphate-based ceramics in a solvent; (2) recovering the calcium phosphate-based ceramics by removing the solvent from a solution in which the calcium phosphate-based ceramic material is dispersed in Step 1; (3) producing a photocurable resin composition by adding a binder resin including a crosslinking agent and a photoinitiator to the calcium phosphate-based ceramics obtained in Step 2; (4) performing 3D rapid prototyping on a bone graft material molded body from the composition for a bone graft material produced in Step 3 by 3D printing of a DLP system; and (5) debinding and sintering organic materials remaining in the bone graft material molded body subjected to prototyping in Step 4.

Abstract: The present invention relates to a method for manufacturing a bone graft material using 3D printing of a DLP system. The method includes (1) dispersing a powder material including calcium phosphate-based ceramics in a solvent; (2) recovering the calcium phosphate-based ceramics by removing the solvent from a solution in which the calcium phosphate-based ceramic material is dispersed in Step 1; (3) producing a photocurable resin composition by adding a binder resin including a crosslinking agent and a photoinitiator to the calcium phosphate-based ceramics obtained in Step 2; (4) performing 3D rapid prototyping on a bone graft material molded body from the composition for a bone graft material produced in Step 3 by 3D printing of a DLP system; and (5) debinding and sintering organic materials remaining in the bone graft material molded body subjected to prototyping in Step 4.

Abstract: An ampoule for storing an implant capable of maintaining humidity includes: a container capable of airtight sealing at least momentarily or temporarily; a partition member which divides an accommodation space inside the container into two spaces, first and second spaces, and allows vaporized water molecules to be transported between the divided spaces; and a water molecule supply source which is accommodated in the first space of the two spaces divided by the partition member and supplies the vaporized water molecules. Therefore, the invention enables the construction of an environment which allows the hydrophilicity of the implant to be maintained for a long time, wherein the hydrophilicity is imparted to and protected from the surface of the implant or a coating layer formed on the surface of the implant.

Abstract: A hydrogel and a method for manufacturing the same. The hydrogel, which can be freely used during treatment irrespective of the shape of a bone defect region, has a decomposition rate capable of being regulated in situ and can thus be rapidly decomposed over a certain time, i.e., after the completion of bone regeneration. Furthermore, a hydrogel membrane using the hydrogel which is applied to a bone defect region irrespective of the shape thereof, and a method for manufacturing the same.

Abstract: A dental bleaching composition includes a dental bleaching agent, a binder, a tartrate, and a solvent.

Abstract: The present invention relates to a dental hydrogel and to a method for manufacturing same, and more particularly, to a hydrogel and to a method for manufacturing wherein the hydrogel, which can be freely used during treatment irrespective of the shape of a bone defect region, has a decomposition rate capable of being regulated in situ and can thus be rapidly decomposed over a certain time, i.e., after the completion of bone regeneration. Furthermore, the present invention relates to a hydrogel membrane using the hydrogel which can be applied to a bone defect region irrespective of the shape thereof, and to a method for manufacturing same.

Abstract: An ampoule for storing an implant capable of maintaining humidity includes: a container capable of airtight sealing at least momentarily or temporarily; a partition member which divides an accommodation space inside the container into two spaces, first and second spaces, and allows vaporized water molecules to be transported between the divided spaces; and a water molecule supply source which is accommodated in the first space of the two spaces divided by the partition member and supplies the vaporized water molecules. Therefore, the invention enables the construction of an environment which allows the hydrophilicity of the implant to be maintained for a long time, wherein the hydrophilicity is imparted to and protected from the surface of the implant or a coating layer formed on the surface of the implant.

Abstract: The present invention relates to a nanoparticle-protein-hydrogel composite comprising (1) a polysaccharide-functionalized nanoparticle comprising a core composed of a biodegradable polymer, a hydrogel surface layer composed of a biocompatible polymer emulsifier, and a polysaccharide physically bound to the core and/or the hydrogel layer; (2) a protein forming a specific binding with the polysaccharide; and (3) a hydrogel matrix composed of a biocompatible polymer as a matrix for the nanoparticle. The present also relates to a drug delivery system and a bone defect replacement matrix comprising the composite for sustained release, and the preparation method thereof. Further, the present invention also provides a method for controlling the release rate of a protein drug by changing the content of the polysaccharide in a unit mass of the nanoparticle and/or by changing the content of the nanoparticle in a unit mass of the composite.

Abstract: The present invention provides a polysaccharide-functionalized nanoparticle, a drug delivery system for controlled release comprising the nanoparticle and a preparation method thereof. In particular, the nanoparticle of the present invention comprises a core of a biodegradable polymer, an outer hydrogel layer of a biocompatible polymer emulsifier and a polysaccharide physically bound to the core and the hydrogel layer, thus enabling to significantly enhance stability and controlled release of a protein drug such as a growth factor.