Patents by Inventor Yongbao Zhu

Yongbao Zhu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Chemokine receptor binding compounds
    Publication number: 20090099205
    Abstract: The present invention relates to chemokine receptor binding compounds, pharmaceutical compositions and their use. More specifically, the present invention relates to modulators of chemokine receptor activity, preferably modulators of CCR5. These compounds demonstrate protective effects against infection of target cells by a human immunodeficiency virus (HIV).
    Type: Application
    Filed: June 14, 2006
    Publication date: April 16, 2009
    Inventors: Yuanxi Zhou, Elyse Bourque, Yongbao Zhu, Jonathan Langille, Markus Metz, Wen Yang, Ernest J. McEachern, Curtis Harwig, Ian R. Baird, Tong-Shuang Li, Renato T. Skerlj
  • CXCR4 CHEMOKINE RECEPTOR BINDING COMPOUNDS
    Publication number: 20080255197
    Abstract: The present invention relates to compounds that bind to chemokine receptors, and having the formula wherein each A, X, Y, R1, R2 and R3 are substituents. The present invention also relates to methods of using such compounds, such as in treating HIV infection and inflammatory conditions such as rheumatoid arthritis. Furthermore, the present invention relates to methods to elevate progenitor and stem cell counts, as well as methods to elevate white blood cell counts, using such compounds.
    Type: Application
    Filed: November 6, 2007
    Publication date: October 16, 2008
    Inventors: Gary J. BRIDGER, Ernest J. McEachern, Renato Skerlj, Dominique Schols, Ian Baird, Al Kaller, Curtis Harwig, Yongbao Zhu, Gang Chen, Krystyna Skupinska
  • CXCR4 chemokine receptor binding compounds
    Patent number: 7291631
    Abstract: The present invention relates to compounds that bind to chemokine receptors, and having the formula wherein each A, X, Y, R1, R2 and R3 are substituents. The present invention also relates to methods of using such compounds, such as in treating HIV infection and inflammatory conditions such as rheumatoid arthritis. Furthermore, the present invention relates to methods to elevate progenitor and stem cell counts, as well as methods to elevate white blood cell counts, using such compounds.
    Type: Grant
    Filed: April 12, 2004
    Date of Patent: November 6, 2007
    Assignee: Genzyme Corporation
    Inventors: Gary J. Bridger, Ernest J. McEachern, Renato Skerlj, Dominique Schols, Ian Baird, Al Kaller, Curtis Harwig, Yongbao Zhu, Gang Chen, Krystyna Skupinska
  • Chemokine receptor binding compounds
    Publication number: 20070066624
    Abstract: The present invention relates to chemokine receptor binding compounds, pharmaceutical compositions and their use. More specifically, the present invention relates to modulators of chemokine receptor activity, preferably modulators of CCR4 or CCR5. In one aspect, these compounds demonstrate protective effects against infection of target cells by a human immunodeficiency virus (HIV).
    Type: Application
    Filed: August 16, 2006
    Publication date: March 22, 2007
    Applicant: AnorMED, Inc.
    Inventors: Yuanxi Zhou, Elyse Bourque, Yongbao Zhu, Ernest McEachern, Curtis Harwig, Renato Skerlj, Gary Bridger, Tong-Shuang Li, Markus Metz
  • Chemokine-binding heterocyclic compound salts, and methods of use thereof
    Publication number: 20060069122
    Abstract: The present invention relates to chemokine-binding heterocyclic compound salts, methods of use thereof, and methods for preparing the same.
    Type: Application
    Filed: September 26, 2005
    Publication date: March 30, 2006
    Inventors: Jason Crawford, Yongbao Zhu, Gang Chen, Ian Baird, Renato Skerlj
  • Chemokine receptor binding heterocyclic compounds with enhanced efficacy
    Publication number: 20050059702
    Abstract: Compounds that interact with the CXCR4 receptor are described. These compounds are useful in treating, for Example, HIV infection and inflammatory conditions such as rheumatoid arthritis, as well as asthma or cancer, and are useful in methods to elevate progenitor and stem cell counts as well as methods to elevate white blood cell counts.
    Type: Application
    Filed: April 22, 2004
    Publication date: March 17, 2005
    Inventors: Gary Bridger, Ernest Mceachern, Renato Skerlj, Dominique Schols, Ian Baird, Ai Kaller, Curtis Harwig, Yongbao Zhu, Gang Chen, Krystyna Skupinska, Markus Metz