Patents by Inventor Yoon S. Lee

Yoon S. Lee has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • HETERODIMERIC ANTIBODIES THAT BIND CD3 AND CLDN6
    Publication number: 20240132584
    Abstract: Provided herein are novel CLDN6 binding domains, and anti-CLDN6×anti-CD3 antibodies that include such CLDN6 binding domains. Also provided herein are methods of using such antibodies for the treatment of CLDN6-associated cancers.
    Type: Application
    Filed: July 5, 2023
    Publication date: April 25, 2024
    Inventors: Matthew S. Faber, Sung-Hyung Lee, Yoon Kyung Kim, Jing Qi, Kendra N. Avery, Seung Y. Chu, Alex Nisthal, Matthew J. Bernett, John R. Desjarlais, Chad Borchert
  • 2,4,5-trisubstituted imidazoles and their use as anti-microbial agents
    Patent number: 8987305
    Abstract: The present invention provides therapeutically effective 2,4,5-trisubstituted imidazole compounds, methods of preparing the same, and compositions comprising the compounds alone or in combination with other agents. The present invention further provides for the use of the compounds as anti-microbial agents. The anti-microbial properties of the compounds include anti-bacterial and/or anti-fungal activity.
    Type: Grant
    Filed: February 27, 2013
    Date of Patent: March 24, 2015
    Assignee: Aptose Biosciences Inc.
    Inventors: Raed H. Al-Qawasmeh, Aiping H. Young, Mario Huesca, Yoon S. Lee
  • 2,4,5-TRISUBSTITUTED IMIDAZOLES AND THEIR USE AS ANTI-MICROBIAL AGENTS
    Publication number: 20130177632
    Abstract: The present invention provides therapeutically effective 2,4,5-trisubstituted imidazole compounds, methods of preparing the same, and compositions comprising the compounds alone or in combination with other agents. The present invention further provides for the use of the compounds as anti-microbial agents. The anti-microbial properties of the compounds include anti-bacterial and/or anti-fungal activity.
    Type: Application
    Filed: February 27, 2013
    Publication date: July 11, 2013
    Inventors: Raed H. Al-Qawasmeh, Aiping H. Young, Mario Huesca, Yoon S. Lee
  • 2,4,5-trisubstituted imidazoles and their use as anti-microbial agents
    Patent number: 8394815
    Abstract: The present invention provides therapeutically effective 2,4,5-trisubstituted imidazole compounds, methods of preparing the same, and compositions comprising the compounds alone or in combination with other agents. The present invention further provides for the use of the compounds as anti-microbial agents. The anti-microbial properties of the compounds include anti-bacterial and/or anti-fungal activity.
    Type: Grant
    Filed: December 22, 2010
    Date of Patent: March 12, 2013
    Assignee: Lorus Therapeutics Inc.
    Inventors: Raed H. Al-Qawasmeh, Aiping H. Young, Mario Huesca, Yoon S. Lee
  • 2,4,5-TRISUBSTITUTED IMIDAZOLES AND THEIR USE AS ANTI-MICROBIAL AGENTS
    Publication number: 20110152337
    Abstract: The present invention provides therapeutically effective 2,4,5-trisubstituted imidazole compounds, methods of preparing the same, and compositions comprising the compounds alone or in combination with other agents. The present invention further provides for the use of the compounds as anti-microbial agents. The anti-microbial properties of the compounds include anti-bacterial and/or anti-fungal activity.
    Type: Application
    Filed: December 22, 2010
    Publication date: June 23, 2011
    Applicant: LORUS THERAPEUTICS INC.
    Inventors: RAED H. AL-QAWASMEH, AIPING H. YOUNG, MARIO HUESCA, YOON S. LEE
  • Neuropilin antisense oligonucleotide sequences and methods of using same to modulate cell growth
    Patent number: 7087580
    Abstract: This invention relates to oligonucleotides complementary to the neuropilin genes which modulate tumor cell growth and angiogenesis in mammals. This invention is also related to methods of using such compounds in inhibiting the growth of tumor cells and angiogenesis in mammals. This invention also relates to pharmaceutical compositions comprising a pharmaceutically acceptable excipient and an effective amount of a compound of this invention.
    Type: Grant
    Filed: April 22, 1999
    Date of Patent: August 8, 2006
    Assignee: GeneSense Technologies, Inc.
    Inventors: Jim A. Wright, Aiping H. Young, Yoon S. Lee
  • Oligonucleotide sequences complementary to thioredoxin or thioredoxin reductase genes and methods of using same to modulate cell growth
    Patent number: 6566514
    Abstract: This invention relates to oligonucleotides complementary to the thioredoxin and thioredoxin reductase genes which modulate tumor cell growth in mammals. This invention is also related to methods of using such compounds in inhibiting the growth of tumor cells in mammals. This invention also relates to pharmaceutical compositions comprising a pharmaceutically acceptable excipient and an effective amount of a compound of this invention.
    Type: Grant
    Filed: October 18, 2000
    Date of Patent: May 20, 2003
    Assignee: GeneSense Technologies Inc.
    Inventors: Jim A. Wright, Aiping H. Young, Yoon S. Lee
  • NEUROPILIN ANTISENSE OLIGONUCLEOTIDE SEQUENCES AND METHODS OF USING SAME TO MODULATE CELL GROWTH
    Publication number: 20030083274
    Abstract: This invention relates to oligonucleotides complementary to the neuropilin genes which modulate tumor cell growth and angiogenesis in mammals. This invention is also related to methods of using such compounds in inhibiting the growth of tumor cells and angiogenesis in mammals. This invention also relates to pharmaceutical compositions comprising a pharmaceutically acceptable excipient and an effective amount of a compound of this invention.
    Type: Application
    Filed: April 22, 1999
    Publication date: May 1, 2003
    Inventors: JIM A. WRIGHT, AIPING H. YOUNG, YOON S. LEE
  • Insulin-like growth factor II antisense oligonucleotide sequences and methods of using same to modulate cell growth
    Publication number: 20020187954
    Abstract: This invention relates to oligonucleotides complementary to the IGF-II genes which modulate tumor cell growth in mammals This invention is also related to methods of using such compounds in inhibiting the growth of tumor cells in mammals This invention also relates to pharmaceutical compositions comprising a pharmaceutically acceptable excipient and an effective amount of a compound of this invention.
    Type: Application
    Filed: April 17, 2002
    Publication date: December 12, 2002
    Applicant: GENESENSE TECHNOLOGIES INC.
    Inventors: Jim A. Wright, Aiping H. Young, Yoon S. Lee
  • Insulin-like growth factor II antisense oligonucleotide sequences and methods of using same to inhibit cell growth
    Patent number: 6417169
    Abstract: This invention relates to oligonucleotides complementary to the IGF-II genes which modulate tumor cell growth in mammals. This invention is also related to methods of using such compounds in inhibiting the growth of tumor cells in mammals. This invention also relates to pharmaceutical compositions comprising a pharmaceutically acceptable excipient and an effective amount of a compound of this invention.
    Type: Grant
    Filed: April 22, 1999
    Date of Patent: July 9, 2002
    Assignee: Genesense Technologies Inc.
    Inventors: Jim A. Wright, Aiping H. Young, Yoon S. Lee