Patents by Inventor Yoon-Sik Lee

Yoon-Sik Lee has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240161190
    Abstract: An energy trading method and system for supporting environmental, social and governance (ESG) management are provided. More specifically, the method and the system enhance environmental, social and governance (ESG) management of a factory by evaluating utility through energy trading between a main grid and a factory having a distributed resource.
    Type: Application
    Filed: October 10, 2023
    Publication date: May 16, 2024
    Inventors: Yoon-Sik YOO, IL Woo LEE
  • Patent number: 11913098
    Abstract: A self-healing alloy contains 5 to 11% by weight of molybdenum (Mo), iron (Fe) as a remainder, and unavoidable impurities. A method for manufacturing the self-healing alloy includes heat treating the alloy or preparing an alloy raw material powder and sintering, homogenizing, and cooling the alloy raw material powder.
    Type: Grant
    Filed: March 22, 2021
    Date of Patent: February 27, 2024
    Assignees: HYUNDAI MOTOR COMPANY, KIA MOTORS CORPORATION, Kookmin University Industry Academy Cooperation Foundation
    Inventors: Kyung Sik Choi, Hoo Dam Lee, Tae Gyu Lee, Byung Ho Min, Young Jun Kwon, Keun Won Lee, Yoon Jung Won, Ki Sub Cho
  • Patent number: 11884852
    Abstract: The present invention is to provide multilayered multiple quantum dot-doped nanoparticles, each of the multiple quantum dot-doped nanoparticles has a structure consisting of an inorganic core particle, a quantum dot-embedded layer, and a silica/quantum dot composite shell. The multiple quantum dot-doped nanoparticles can be used to detect biomolecules with improved quantum yield (QY) and brightness while maintaining a large area covered by the quantum dots and stable bonds of the quantum dots. Therefore, the multiple quantum dot-doped nanoparticles are suitable for bioapplications, including bioplatforms and highly sensitive methods for detecting biomolecules.
    Type: Grant
    Filed: September 28, 2018
    Date of Patent: January 30, 2024
    Assignees: BIOSQUARE INC., KONKUK UNIVERSITY INDUSTRIAL COOPERATION CORP
    Inventors: Bong Hyun Jun, Sung Wook Yoon, Yoon Sik Lee, Dong Ok Choi, Xuan Hung Pham, Tae Han Kim, Jung Won Kim
  • Patent number: 11795065
    Abstract: The present invention provides iron oxide magnetic particles including an iron oxide and MXn, wherein M includes one or more selected from the group consisting of Cu, Sn, Pb, Mn, Ir, Pt, Rh, Re, Ag, Au, Pd, and Os, X includes one or more selected from the group consisting of F, Cl, Br, and I, and n is an integer of 1 to 6.
    Type: Grant
    Filed: February 26, 2021
    Date of Patent: October 24, 2023
    Assignee: ZTI BIOSCIENCES CO., LTD.
    Inventors: Hyungseok Chang, Sei Jin Park, Yong-Sun Park, Ji Young Ryu, Yoon-Sik Lee
  • Patent number: 11780739
    Abstract: The present invention provides a method for preparing iron oxide magnetic particles and iron oxide magnetic particles prepared thereby, wherein the method includes (a) synthesizing a complex by reacting iron and one or more compounds selected from the group consisting of an aliphatic hydrocarbonate having 4 to 25 carbon atoms and an amine compound, (b) synthesizing an iron oxide crystal nucleus by mixing the complex with a mixture of an unsaturated aliphatic hydrocarbon-based compound having 4 to 25 carbon atoms and an ether-based compound, and (c) forming a shell by mixing the iron oxide crystal nucleus and an MXn compound with a mixture of an unsaturated aliphatic hydrocarbon-based compound having 4 to 25 carbon atoms and an ether-based compound, wherein M is a heavy atom element, X is a halogen element, and n is an integer of 1 to 6.
    Type: Grant
    Filed: February 26, 2021
    Date of Patent: October 10, 2023
    Assignee: ZTI BIOSCIENCES CO., LTD.
    Inventors: Hyungseok Chang, Sei Jin Park, Yong-Sun Park, Ji Young Ryu, Yoon-Sik Lee
  • Publication number: 20230127444
    Abstract: Disclosed is a composition comprising iron oxide magnetic particles. The composition is delivered to a liver in a hepatocyte-specific manner to minimize damage to other organs, and is safely excreted from a body within a few weeks. Further, the particles have excellent hepatocyte targeting ability, and thus are used as a liver cancer treatment agent and a hepatocyte targeting carrier.
    Type: Application
    Filed: October 21, 2021
    Publication date: April 27, 2023
    Applicant: ZTI BIOSCIENCES CO, LTD.
    Inventors: Hyungseok CHANG, Yoon-Sik LEE, Ji Young RYU, Hyoungseok LEE, Yong-Sun PARK
  • Patent number: 11389568
    Abstract: The present invention relates to a biopolymer-based hydrogel as a functional biomaterial produced by crosslinking in the presence of a photopolymerization initiator. The hydrogel of the present invention is elastic so as to be adapted to various shapes in both in vivo and in vitro applications. It is biocompatible, achieving maximum effects on wound healing as wound dressing and tissue adhesion preventing material. The present invention also relates to a method for producing the biocompatible hydrogel.
    Type: Grant
    Filed: April 29, 2019
    Date of Patent: July 19, 2022
    Assignee: Science@Home Inc.
    Inventors: Yoon Sik Lee, Byung Gee Kim, Sung Jun Park, Sang Hyuk Lee
  • Patent number: 11287385
    Abstract: Composite particles are provided. The composite particles can comprise: a base particle; a metal layer encompassing the base particle and having a surface on which a plurality of gaps are formed; and markers provided on the metal layer and also provided within the plurality of gaps of the metal layer.
    Type: Grant
    Filed: September 20, 2018
    Date of Patent: March 29, 2022
    Assignees: INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY ERICA CAMPUS, SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION
    Inventors: Jong-Ho Kim, Yoon-Sik Lee, Jin-Kyoung Yang
  • Publication number: 20210380876
    Abstract: The present invention provides a biological use including a bioplatform and a method for detecting a high-sensitivity biomolecule by providing improved quantum yield (QY) and brightness when detecting biomolecules by preparing nanoparticles, which are doped in multiple quantum dots and have a structure of inorganic core particles, a quantum dot buried layer and a silica/quantum dot composite shell, while maintaining a high occupancy and stable bonding.
    Type: Application
    Filed: September 28, 2018
    Publication date: December 9, 2021
    Inventors: Bong Hyun JUN, Sung Wook YOON, Yoon Sik LEE, Dong Ok CHOI, Xuan Hung PHAM, Tae Han KIM, Jung Won KIM
  • Publication number: 20210327621
    Abstract: The present invention provides iron oxide magnetic particles including an iron oxide and MXn, wherein M includes one or more selected from the group consisting of Cu, Sn, Pb, Mn, Ir, Pt, Rh, Re, Ag, Au, Pd, and Os, X includes one or more selected from the group consisting of F, Cl, Br, and I, and n is an integer of 1 to 6.
    Type: Application
    Filed: February 26, 2021
    Publication date: October 21, 2021
    Inventors: Hyungseok CHANG, Sei Jin PARK, Yong-Sun PARK, Ji Young RYU, Yoon-Sik LEE
  • Publication number: 20210317005
    Abstract: The present invention provides a method for preparing iron oxide magnetic particles and iron oxide magnetic particles prepared thereby, wherein the method includes (a) synthesizing a complex by reacting iron and one or more compounds selected from the group consisting of an aliphatic hydrocarbonate having 4 to 25 carbon atoms and an amine compound, (b) synthesizing an iron oxide crystal nucleus by mixing the complex with a mixture of an unsaturated aliphatic hydrocarbon-based compound having 4 to 25 carbon atoms and an ether-based compound, and (c) forming a shell by mixing the iron oxide crystal nucleus and an MXn compound with a mixture of an unsaturated aliphatic hydrocarbon-based compound having 4 to 25 carbon atoms and an ether-based compound, wherein M is a heavy atom element, X is a halogen element, and n is an integer of 1 to 6.
    Type: Application
    Filed: February 26, 2021
    Publication date: October 14, 2021
    Inventors: Hyungseok CHANG, Sei Jin PARK, Yong-Sun PARK, Ji Young RYU, Yoon-Sik LEE
  • Publication number: 20200217797
    Abstract: Composite particles are provided. The composite particles can comprise: a base particle; a metal layer encompassing the base particle and having a surface on which a plurality of gaps are formed; and markers provided on the metal layer and also provided within the plurality of gaps of the metal layer.
    Type: Application
    Filed: September 20, 2018
    Publication date: July 9, 2020
    Applicants: INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY ERICA CAMPUS, SEOUL NATIONAL UNIVERSITY R & DB FOUNDATION
    Inventors: Jong-Ho Kim, Yoon-Sik Lee, Jin-Kyoung Yang
  • Patent number: 10686203
    Abstract: A peptide-inorganic material composite film according to an exemplary embodiment of the present invention includes: a unit peptide including 4 to 15 amino acids, and a transition metal oxide hybridized with the unit peptide, wherein the unit peptide includes at least two tyrosines, and the plurality of unit peptides positioned adjacent to each other have a form in which the tyrosines are linked.
    Type: Grant
    Filed: December 8, 2017
    Date of Patent: June 16, 2020
    Assignee: SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION
    Inventors: Ki Tae Nam, Yoon-Sik Lee, Young-O Kim, Jaehun Lee, Ik Rang Choe
  • Publication number: 20190314556
    Abstract: The present invention relates to a biopolymer-based hydrogel as a functional biomaterial produced by crosslinking in the presence of a photopolymerization initiator. The hydrogel of the present invention is elastic so as to be adapted to various shapes in both in vivo and in vitro applications. It is biocompatible, achieving maximum effects on wound healing as wound dressing and tissue adhesion preventing material. The present invention also relates to a method for producing the biocompatible hydrogel.
    Type: Application
    Filed: April 29, 2019
    Publication date: October 17, 2019
    Inventors: Yoon Sik LEE, Byung Gee KIM, Sung Jun PARK, Sang Hyuk LEE
  • Publication number: 20180166722
    Abstract: A peptide-inorganic material composite film according to an exemplary embodiment of the present invention includes: a unit peptide including 4 to 15 amino acids, and a transition metal oxide hybridized with the unit peptide, wherein the unit peptide includes at least two tyrosines, and the plurality of unit peptides positioned adjacent to each other have a form in which the tyrosines are linked.
    Type: Application
    Filed: December 8, 2017
    Publication date: June 14, 2018
    Inventors: Ki Tae NAM, Yoon-Sik LEE, Young-O KIM, Jaehun LEE, Ik Rang CHOE
  • Patent number: 9885716
    Abstract: Provided is a nanoprobe based on a self-replicating biological material. The nanoprobe includes a binding agent existing in a first region of the biological material and capable of binding specifically to a target analyte, and nanoparticles existing in a second region of the biological material and providing an optical detection signal. The use of the nanoprobe enables quantitative analysis and multiplexed analysis of a target. In addition, the nanoprobe is easy to fabricate on a large scale.
    Type: Grant
    Filed: May 3, 2013
    Date of Patent: February 6, 2018
    Assignee: SNU R&DB FOUNDATION
    Inventors: Yoon-Sik Lee, Ki Tae Nam, Jun ho Chung, Dae Hong Jeong, Hye Eun Lee
  • Patent number: 9833145
    Abstract: Provided are a method for simultaneously detecting fluorescence and Raman signals for multiple fluorescence and Raman signal targets, and a medical imaging device for simultaneously detecting multiple targets using the method. The method includes: injecting at least one marker particle comprising Raman markers and receptors into the body of an animal, which can be a human; irradiating a laser beam onto the body of the animal; and detecting the optical signals emitted by the marker particle after the irradiation of the laser beam separately as fluorescence signals and Raman signals. The simultaneous detection of multiple targets may be performed even without scanning optical signals emitted by the marker particle individually with different optical fibers. As an examination may be performed by injecting surface-enhanced Raman marker particles, weak Raman signals may be augmented so as to obtain a more accurate diagnosis result in real time.
    Type: Grant
    Filed: January 4, 2017
    Date of Patent: December 5, 2017
    Assignee: SNU R&DB FOUNDATION
    Inventors: Dae Hong Jeong, Keon Wook Kang, Dong Soo Lee, Yoon Sik Lee, Gun Sung Kim, Bong Hyun Jun, Jin Chul Paeng, Ho Young Lee, Yun Sang Lee
  • Patent number: 9696301
    Abstract: The present invention relates to a method for separating nanoparticles and analyzing a biological substance using a microfluidic chip. The microfluidic chip of the present invention is effective in more sensitively and precisely detecting an analyte. According to the present invention, the use of the microfluidic chip enables the separation of nanoparticles through separation holes on the basis of size, achieving highly reliable analysis of a biological substance. In conclusion, the microfluidic chip of the present invention uses separation holes adapted to the size of nanoparticles to greatly increase the reliability of analysis of a biological substance, which will contribute to a marked improvement in the reliability of analysis based on microfluidics and a microfluidic system.
    Type: Grant
    Filed: November 20, 2013
    Date of Patent: July 4, 2017
    Assignee: Seoul National University R&DB Foundation
    Inventors: Yong-Kweon Kim, Yoon-Sik Lee, Yul Koh, Homan Kang
  • Publication number: 20170112380
    Abstract: Provided are a method for simultaneously detecting fluorescence and Raman signals for multiple fluorescence and Raman signal targets, and a medical imaging device for simultaneously detecting multiple targets using the method. The method includes: injecting at least one marker particle comprising Raman markers and receptors into the body of an animal, which can be a human; irradiating a laser beam onto the body of the animal; and detecting the optical signals emitted by the marker particle after the irradiation of the laser beam separately as fluorescence signals and Raman signals. The simultaneous detection of multiple targets may be performed even without scanning optical signals emitted by the marker particle individually with different optical fibers. As an examination may be performed by injecting surface-enhanced Raman marker particles, weak Raman signals may be augmented so as to obtain a more accurate diagnosis result in real time.
    Type: Application
    Filed: January 4, 2017
    Publication date: April 27, 2017
    Inventors: Dae Hong JEONG, Keon Wook KANG, Dong Soo LEE, Yoon Sik LEE, Gun Sung KIM, Bong Hyun JUN, Jin Chul PAENG, Ho Young LEE, Yun Sang LEE
  • Publication number: 20150314291
    Abstract: The present invention relates to a method for separating nanoparticles and analyzing a biological substance using a microfluidic chip. The microfluidic chip of the present invention is effective in more sensitively and precisely detecting an analyte. According to the present invention, the use of the microfluidic chip enables the separation of nanoparticles through separation holes on the basis of size, achieving highly reliable analysis of a biological substance. In conclusion, the microfluidic chip of the present invention uses separation holes adapted to the size of nanoparticles to greatly increase the reliability of analysis of a biological substance, which will contribute to a marked improvement in the reliability of analysis based on microfluidics and a microfluidic system.
    Type: Application
    Filed: November 20, 2013
    Publication date: November 5, 2015
    Applicant: SNU R&DB FOUNDATION
    Inventors: Yong-Kweon KIM, Yoon-Sik LEE, Yul KOH, Homan KANG