Abstract: The present invention relates to phthalazinone derivatives, including pharmaceutical compositions and for the preparation of phthalazinone derivatives. And more particularly the present invention provided a pharmaceutical composition of phthalazinone derivatives for inhibiting activity of the Poly(ADP-riboside) polymerase enzyme.

Abstract: A lighting apparatus including a plurality of frames connected to each other in the lengthwise direction; a connector, which is arranged between the plurality of frames and interconnects the plurality of frames by including a portion inserted into one of the plurality of frames, and including another portion inserted into the other one of the plurality of frames; and a light source arranged on the plurality of frames.

Abstract: The present invention relates to phthalazinone derivatives, including pharmaceutical compositions and for the preparation of phthalazinone derivatives. And more particularly the present invention provided a pharmaceutical composition of phthalazinone derivatives for inhibiting activity of the Poly(ADP-riboside) polymerase enzyme.

Abstract: A bio-chip has a base plate, and a fluid resin layer positioned on the base plate and having a plurality of convexo-concave structures that are uniformly arranged in line. Side walls of the structures form reflecting films to form a Fabry-Perot interferometer structure. The bio-chip is used to detect an analyte provided to the bio-chip, so that it is possible to rapidly analyze the small amount of samples and to realize the detection sensitivity relatively higher than the conventional method.

Abstract: The present invention relates to the screening method of antagonistic material of integrin using the protein chip and useful peptides screened thereby. The protein chip used in the present invention is unique substrate coated with new material, calixarene derivative, which can keep uniform and high activities of proteins. Integrin receptor protein is arrayed high densely on the chip, and materials (protein, peptide, small molecules and so on) specifically inhibiting the binding of ligand can be screened therewith. The integrins used in the present invention are integrin av f3 3 and integrin a1, b j3 3, and new antagonistic peptides screened from peptide library have high binding affinity.

Abstract: The present invention relates to the screening method of antagonistic material of integrin using the protein chip and useful peptides screened thereby. The protein chip used in the present invention is unique substrate coated with new material, calixarene derivative, which can keep uniform and high activities of proteins. Integrin receptor protein is arrayed high densely on the chip, and materials (protein, peptide, small molecules and so on) specifically inhibiting the binding of ligand can be screened therewith. The integrins used in the present invention are integrin av f3 3 and integrin a1, b j3 3, and new antagonistic peptides screened from peptide library have high binding affinity.

Abstract: A 2?-deoxyuridine derivative of formula I is bioavailable and thermally stable and forms a gel in water at a low concentration; and, can be employed as a drug delivery vehicle: