Abstract: Providing an agent for activating a sirtuin gene and an application thereof. The agent for activating a sirtuin gene is characterized to contain an egg shell membrane ingredient, for example an egg shell membrane-containing powder or soluble egg shell membrane ingredient.

Abstract: To provide an insulin resistance-improving agent, and the application thereof. The insulin resistance-improving agent contains an eggshell membrane component, for example, an eggshell membrane-containing powder or a soluble eggshell membrane component. Further, the eggshell membrane-containing powder to be used is a fine powder, and preferably has a volume average particle size of 6 ?m or less, and/or a volume maximum particle size of 20 ?m or less, but these particle sizes are not limited to the values.

Abstract: To provide an activator of gene expression of molecular chaperone gene and applications thereof. This activator of gene expression of molecular chaperone gene contains an eggshell membrane component, for example, a powder containing eggshell membrane or a soluble eggshell membrane component. Moreover, the powder containing eggshell membrane used in the present invention may be a fine powder preferably having 6 ?m or less in the mean volume particle diameter of the fine powder containing eggshell membranes, and/or 20 ?m or less in the maximum volume particle diameter thereof, but not limited to these values.

Abstract: Providing an agent for activating a sirtuin gene and an application thereof. The agent for activating a sirtuin gene is characterized to contain an egg shell membrane ingredient, for example an egg shell membrane-containing powder or soluble egg shell membrane ingredient.

Abstract: A garment is provided with a main part which consists of a front body section, a back body section and sleeves extending from front and back body sections toward both arm sides over shoulders, and a pair of first tightening parts separately placed in right and left areas located at the positions of right and left deltoid muscles covering the boundary of the wearer's shoulder and upper arm in the back side, wherein the front and back body sections and the upper arm sections of the sleeves comprise at least two kinds of stretch materials, which differ in stretchability from each other, including a material for the main part and a material for the first tightening parts having a lower stretchability than the main part.