Patents by Inventor Yoshiaki Kawashima

Yoshiaki Kawashima has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20090052204
    Abstract: The present invention provides a thin, low-power consumption, lightweight, and inexpensive surface light emitting apparatus using LEDs in conjunction with a light conducting member having a plurality of light conducting rods. More specifically, the surface light emitting apparatus of the invention comprises: a light conducting member constructed from a plurality of light conducting rods and having an end face and a light-emitting face; a light source for emitting light into the light conducting member through the end face; and light deflecting means for causing the light introduced through the end face of the light conducting member to emerge from the light-emitting face of the light conducting member.
    Type: Application
    Filed: February 19, 2007
    Publication date: February 26, 2009
    Inventors: Yoshiaki Kawashima, Yutaka Omura
  • Publication number: 20080248119
    Abstract: A strong pressure and a strong shearing force are exerted to a mixture, constituted of two kinds or more of powder materials including a drug powder, while causing the mixture to pass between a press section (26) of a press head (24) and a receiving surface (25) of a cylindrical rotator (23), thereby combining the drug powder with the other powder material. For example, at least one of a drug and a biocompatible polymer is made into a nano particle whose average particle diameter is less than 1000 nm, and the nano particle is made into a composite in accordance with a dry mechanical particle combining method, so as to form a polymer nano composite particle. Thus, it is possible to produce a composite particle, which contains a drug under a stable condition, in a short time, and it is possible to remarkably improve its handling property without losing advantages of the nano particle.
    Type: Application
    Filed: February 7, 2008
    Publication date: October 9, 2008
    Inventors: Yoshiaki Kawashima, Hiromitsu Yamamoto, Toyokazu Yokoyama, Hiroyuki Tsujimoto
  • Patent number: 7022311
    Abstract: The present invention is aimed at providing a dry powder inhalation with minimal adhesive-agglomerative property during storage and with a good inhalation behavior for a pharmaceutically active ingredient, and is a dry powder inhalation wherein at least an active ingredient is adhered to the surface of a carrier particle comprised of erythritol and/or trehalose. It is also a dry powder inhalation wherein at least S-36496 and/or Pralmorelin dihydrochloride is adhered to the surface of the carrier particle. It is further a dry powder inhalation wherein at least an active ingredient and a surface modifier are adhered to the surface of the carrier particle. It is also a preparation method of these. Said dry powder inhalation may be applied to the capsules for use in an inhaler device.
    Type: Grant
    Filed: October 12, 2000
    Date of Patent: April 4, 2006
    Assignee: Kaken Pharmaceutical Co., Ltd.
    Inventors: Moriyuki Ohkuma, Keiko Matsumoto, Otomo Okuda, Yasutomi Kato, Yoshiaki Kawashima
  • Publication number: 20050191357
    Abstract: A strong pressure and a strong shearing force are exerted to a mixture, constituted of two kinds or more of powder materials including a drug powder, while causing the mixture to pass between a press section (26) of a press head (24) and a receiving surface (25) of a cylindrical rotator (23), thereby combining the drug powder with the other powder material. For example, at least one of a drug and a biocompatible polymer is made into a nano particle whose average particle diameter is less than 1000 nm, and the nano particle is made into a composite in accordance with a dry mechanical particle combining method, so as to form a polymer nano composite particle. Thus, it is possible to produce a composite particle, which contains a drug under a stable condition, in a short time, and it is possible to remarkably improve its handling property without losing advantages of the nano particle.
    Type: Application
    Filed: September 12, 2002
    Publication date: September 1, 2005
    Inventors: Yoshiaki Kawashima, Masuo Hosokawa, Hirofumi Takeuchi, Hiromitsu Yamamoto, Masaru Iwato, Kazuki Suhara, Toyokazu Yokoyama, Hiroyuki Tsujimoto, Akira Kondo, Tsunehiro Yoshidomi, Yoshiyuki Inoue, Hisato Eitoku, Naotoshi Kinoshita
  • Patent number: 5874877
    Abstract: A circuit breaker with a completely electromagnetic type overcurrent tripping device has a flexibility for changes in the production schedule of the overcurrent tripping device. An overcurrent tripping device for each pole is integrally housed in a common unit case, which is then inserted into a case of the circuit breaker. In this case, a yoke of the overcurrent tripping device is combined with an oil dash pot inserted into a coil, and the combined parts are pressed and fixed in the unit case without soldering. Thus, the coil, which is changed depending on the rated current, and the yoke and oil dash pot which are common products, can be separately stored prior to assembly, thereby enabling flexible responses to changes in the production schedule. In addition, the yoke and the oil dash pot need not be soldered and are fixed individually to the unit case, thereby reducing the number of assembly operations.
    Type: Grant
    Filed: July 29, 1997
    Date of Patent: February 23, 1999
    Assignee: Fuji Electric Co., Ltd.
    Inventors: Yoshiaki Kawashima, Kazuhiko Satoh, Tadahisa Aoki, Makoto Ogasawara
  • Patent number: 5560930
    Abstract: A method permits the easy preparation of an aqueous emulsion for coating solid pharmaceutical preparations through emulsification in water without addition of additives such as emulsifying agents, polymerization initiators, chain transfer agents, salts and plasticizers. A cellulosic polymer is dissolved in an organic solvent miscible in water in any rate or a mixed solvent comprising the organic solvent and water to give a polymer solution. The polymer solution is mixed with water to disperse the solution in water and thereafter the organic solvent is removed to form an aqueous emulsion for coating solid pharmaceutical preparations. If ethyl cellulose is used as a coating base, ethyl cellulose is first dissolved in a non-hydrophilic solvent to give a non-hydrophilic solution thereof.
    Type: Grant
    Filed: December 21, 1994
    Date of Patent: October 1, 1996
    Assignee: Shin-Etsu Chemical Co., Ltd.
    Inventors: Naosuke Maruyama, Hiroyasu Kokubo, Yoshiaki Kawashima
  • Patent number: 5180522
    Abstract: A colloid solution for preparing a suspension, containing one or more components selected from Group A and one or more components selected from Group B as dispersoids, and water as a dispersant medium, the colloid solution being at a pH such that suspensoid particles added thereto are positively charged; wherein Group A consists of xylitol, D-sorbitol, D-mannitol, lactose, saccharose, cyclodextrin, maltose, D-fructose, D-glucose and galactose; and Group B consists of sodium carboxymethylcellulose, sodium alginate, sodium polyacrylate and gum arabic.
    Type: Grant
    Filed: March 4, 1988
    Date of Patent: January 19, 1993
    Assignees: Yoshiaki Kawashima, Showa Yakuhin Kako Co., Ltd.
    Inventors: Yoshiaki Kawashima, Taro Iwamoto, Kikuo Tejima
  • Patent number: 5087455
    Abstract: A granular medicine with slow drug-release characteristics that is sufficiently absorbed in the intestines, in which the granular medicine has a hollow spherical structure, a drug is dispersed in the shell, which mainly consists of an enteron-soluble polymer. The method for preparing the medicine includes the steps of: (a) mixing a hydrophilic or hydrophobic drug with an enteron-soluble polymer in a mixture of an aliphatic alcohol and a chlorohydrocarbon; and (b) pouring this mixture into water or an aqueous medium, and stirring the solution to precipitate the medicine.
    Type: Grant
    Filed: September 20, 1990
    Date of Patent: February 11, 1992
    Assignees: Showa Yakuhin Kako Co. Ltd., Yoshiaki Kawashima
    Inventors: Toshiyuki Niwa, Yoshiaki Kawashima, Hirofumi Takeuchi, Yoji Ito
  • Patent number: 5057323
    Abstract: A granular medicine with slow drug-release characteristics that is sufficiently absorbed in the intestines, in which the granular medicine has a hollow spherical structure, a drug is dispersed in the shell, which mainly consists of an enteron-soluble polymer. The method for preparing the medicine includes the steps of: (a) mixing a hydrophilic or hydrophobic drug with an enteron-soluble polymer in a mixture of an aliphatic alcohol and a chlorohydrocarbon; and (b) pouring this mixture into water or an aqueous medium, and stirring the solution to precipitate the medicine.
    Type: Grant
    Filed: June 19, 1989
    Date of Patent: October 15, 1991
    Assignees: Showa Yakuhin Kako Co., Ltd., Yoshiaki Kawashima
    Inventors: Toshiyuki Niwa, Yoshiaki Kawashima, Hirofumi Takeuchi, Yoji Ito
  • Patent number: 4726966
    Abstract: This invention provides a simple method for preparing granular ibuprofen microsphere whose surface is coated with acrylic acid resin. By this method granulation of ibuprofen and coating of its surface can be simultaneously accomplished. Namely, the method of preparation includes the steps of: (a) dissolving ibuprofen with acrylic acid resin into lower aliphatic alcohol, acetone, methylene chloride or N,N-dimethylformamide; and (b) depositing coated granular ibuprofen microsphere by mixing the solution of step (a) with water and by stirring the mixed solution.
    Type: Grant
    Filed: November 25, 1986
    Date of Patent: February 23, 1988
    Assignee: Showa Shinyaku Co., Ltd.
    Inventors: Yoshiaki Kawashima, Hirofumi Takeuchi, Toshiyuki Niwa, Tetsurou Handa