Publication number: 20070072901
Abstract: A compound of Formula (I): or a salt or solvate thereof, wherein R1 represents a phenyl or napthyl group, each of which is substituted by one or more substituents independently selected from —OH, —C1-6alkyl, C1-6haloalkyl, —OCH2OCH3, —C1-6alkoxy, and -halogen, or a mono or bicyclic heteroaryl group comprising 1, 2 or 3 nitrogen atoms, optionally substituted by —C1-6alkoxy, —C1-6alkyl, C1-6haloalkyl or ?O; R2 represents H, benzimidazolyl, benzothiazolyl, piperonyl, isoquinolinyl, quinolinyl, or phenyl wherein said phenyl is optionally substituted by —NR3R4, —C1-4alkoxy, —C1-6alkyl, —CONR3R4, —SO2NR 3R4, —NHCONR3R4, —NHCOC1-6alkyl, —C1-6haloalkyl, phenoxy, NH2 substituted phenoxy, —C1-3alkyl, —C1-3alkoxy, —CF3, or -5 membered heteroaryl group comprising one or two nitrogen atoms; R3 and R4 are independently selected from H, —C1-6alkyl, —C1-3alkylNR5R6; and R5 and R6 are independently H or C1-3alkyl.
Type:
Application
Filed:
November 17, 2004
Publication date:
March 29, 2007
Inventor:
Yoshiaki Washio