Abstract: An ultrasound image processing apparatus includes a reception section that receives an ultrasound image and discriminator determination information from an external apparatus, the ultrasound image being generated based on a reception signal acquired by an ultrasound probe that transmits and receives an ultrasound wave to and from a subject, the discriminator determination information allowing determination of a discriminator that discriminates a target in the ultrasound image, and one or more first hardware processors, in which the one or more first hardware processors determine one from among a plurality of discriminators to which the ultrasound image is to be input, the one discriminator being determined based on the discriminator determination information, input the ultrasound image to the determined discriminator to acquire a discrimination result to be output from the determined discriminator.

Abstract: An apparatus that includes a semiconductor substrate having first and second gate trenches arranged in parallel and extending in a first direction, and first and second gate electrodes embedded in the first and second gate trenches, respectively, via a gate insulating film. Each of the first and second gate electrodes includes a first conductive film located at a bottom of the respective first and second gate trenches and a second conductive film stacked on the first conductive film. The second conductive film included in a first portion of the second gate electrode is thinner than the second conductive film included in a first portion of the first gate electrode which is arranged adjacently to the first portion of the second gate electrode in a second direction crossing to the first direction. The second conductive film is lower in work function than the first conductive film.

Abstract: A sealing device according to at least one embodiment includes not less than three arc-shaped fins arranged in an axial direction. The arc-shaped fins include: a first fin which is one of two outermost fins located on an outermost side in the axial direction; a second fin disposed adjacent to the first fin in the axial direction; and at least one third fin disposed opposite to the first fin across the second fin in the axial direction. It is preferable that the third fin is disposed to be inclined with respect to a radial direction such that a tip end portion is located on a side of the first fin in the axial direction relative to a base end portion, and the third fin has a larger inclination angle than the first fin or the second fin with respect to the radial direction.

Abstract: A sampling apparatus 1 samples a culture medium in a bioreactor 11. A pump 21 circulates the culture medium in the bioreactor 11 via a flow path 41 by leading out the culture medium from the bioreactor 11 into the flow path 41 and introducing the culture medium from the flow path 41 into the bioreactor 11. A valve 22 is provided in the middle of the flow path 41, and switches a flow path such that the culture medium circulated in the flow path 41 flows out to a branch flow path 42 to be sampled.

Abstract: Disclosed herein is an apparatus that includes a semiconductor substrate having source/drain regions and a gate trench located between the source/drain regions; and a gate electrode embedded in the gate trench via a gate insulating film. The gate electrode includes a first polycrystalline silicon film located at a bottom of the gate trench and a metal film stacked on the first polycrystalline silicon film. The first polycrystalline silicon film is doped with boron.

Abstract: A sampling apparatus 1 samples a culture medium in a bioreactor 11. A pump 21 circulates the culture medium in the bioreactor 11 via a flow path 41 by leading out the culture medium from the bioreactor 11 into the flow path 41 and introducing the culture medium from the flow path 41 into the bioreactor 11. A valve 22 is provided in the middle of the flow path 41, and switches a flow path such that the culture medium circulated in the flow path 41 flows out to a branch flow path 42 to be sampled.

Abstract: A chromatography carrier capable of removing an antibody dimer from a solution containing an antibody monomer. The chromatography carrier includes a base carrier containing porous particles and a hydrophobic ligand bound to the base carrier, and has an electric conductivity of 34 mS/cm or less measured by a gradient elution test. The porous particles preferably have an average particle diameter of 66 to 150 ?m, and the hydrophobic ligand preferably has at least one selected from a group consisting of phenyl, n-butyl, n-hexyl, n-octyl, and n-octadecyl.

Abstract: An optical distance measurement device includes: a photodetector including PDs for receiving interference light output from an optical interference unit and outputting detection signals of the interference light; and a switch for selecting one of the detection signals output from the PDs, in which a distance calculation unit calculates a distance to a measurement object on the basis of the detection signal selected by the switch.

Abstract: When a stirring device 11 performs processing of stirring a mixed solution in a test tube S, a holding mechanism 13 and a movement mechanism 14 are operated so that the test tube S is moved to a position of B2. Then, in the test tube S, the cells attached to the inner surface of the test tube S and the liquid are separated. Further, the cells attached to the inner surface of the test tube S are detected by a color sensor 152. Therefore, it is possible to reduce the work for determining the end of the stirring processing by the user. As a result, the workability of the user when using the stirring device 11 can be improved.

Abstract: A stirring device 11 includes a stirring mechanism 7 and a control unit 15. The stirring mechanism 7 includes a motor 74 and a pedestal portion 77. In the stirring device 11, the motor 74 repeats forward rotation and reverse rotation alternately under the control of the control unit 15. Then, the pedestal portion 77 repeats turning in one direction and turning in the other direction alternately. As a result, the test tube S repeats the movement in one direction and the movement in the other direction alternately, and the vortex rotating in one direction and the vortex rotating in the other direction are alternately generated in the mixed solution in the test tube S. Then, the mixed solution in the test tube S is stirred to be rotated, and is stirred to be moved in the vertical direction. Therefore, the mixed solution in the test tube S can be efficiently stirred. As a result, the time required for stirring the mixed solution in the test tube S can be shortened.

Abstract: An adsorbent, which can be produced by a method in which a particle size, a pore size, a specific surface area or the like can be easily controlled, and is suitable for isolation of biomolecules. The adsorbent contains aggregates of calcium phosphate-based particles, and has an average pore size of 15 to 36 nanometers and a specific surface area of 40 to 90 m2/mL when measurement is carried out by mercury porosimetry.

Abstract: An optical distance measurement device includes: a photodetector including PDs for receiving interference light output from an optical interference unit and outputting detection signals of the interference light; and a switch for selecting one of the detection signals output from the PDs, in which a distance calculation unit calculates a distance to a measurement object on the basis of the detection signal selected by the switch.

Abstract: An insulated DC-DC converter includes a substrate, a transformer, a primary side electronic component and a primary side wire defining a primary side circuit together with a primary winding, a secondary side electronic component and a secondary side wire defining a secondary side circuit insulated from the primary side circuit, together with a secondary winding, the secondary side electronic component including a choke coil, and an inter-circuit electronic component and an inter-primary side circuit wire connected over the primary side circuit and the secondary side circuit while insulating the primary side circuit and the secondary side circuit from each other in a DC manner.

Abstract: An antibody purification method, including bringing a solution containing an antibody and HCP into contact with a chromatography media to separate the antibody and the HCP, wherein the chromatography media contains a base media containing porous particles, and a compound having a plurality of primary amino groups bonded to the base media, and 20 to 55% of the primary amino groups in the compound having the plurality of primary amino groups are modified with a hydrophobic group, and collection efficiency of the antibody is 85% or more, and an amount of the HCP in an antibody solution after purification is less than 45 ppm.

Abstract: In one embodiment, the invention provides a method of treating a subject who suffers from a neoplasm (including a cancer such as a radiotherapeutic-resistant cancer) by administering to the subject a therapeutically effective amount of (a) 5-formyl-2?-deoxyuridine (fdU or foUdR) or a 5-formyl-2?-deoxyuridine derivative, optionally in combination with 5-hydroxy-2?-deoxyuridine (hUdR); and (b) at least one composition selected from the group consisting of either 5-fluorouracil (5-FU), a 5-FU prodrug (e.g. 5-fluoro-2?-deoxyuridine (FdU)) or 5-FU metabolite. In a preferred embodiment, a subject who suffers from colorectal cancer (CRC) or metastatic colorectal cancer (mCRC) is treated with a therapeutically-effective amount of fdU and either 5-FU or the 5-FU prodrug 5-fluoro-2?-deoxyuridine (FdU). Related pharmaceutical compositions are also provided.

Abstract: A method for preparing a chromatography medium having the properties of high virus adsorption and high fluidity, and a method for producing a virus vaccine using the chromatography medium are provided. The chromatography medium is obtained by forming a sulfated polysaccharide bound with porous particles having an exclusion limit molecular weight of 6000 Da or less when pure water is used as mobile phase and standard polyethylene glycol is used and an average particle size in the range of 30-200 ?m.

Abstract: An insulated DC-DC converter includes a substrate, a transformer, a primary side electronic component and a primary side wire defining a primary side circuit together with a primary winding, a secondary side electronic component and a secondary side wire defining a secondary side circuit insulated from the primary side circuit, together with a secondary winding, the secondary side electronic component including a choke coil, and an inter-circuit electronic component and an inter-primary side circuit wire connected over the primary side circuit and the secondary side circuit while insulating the primary side circuit and the secondary side circuit from each other in a DC manner.

Abstract: In one embodiment, the invention provides a method of treating a subject who suffers from a neoplasm (including a cancer such as a radiotherapeutic-resistant cancer) by administering to the subject a therapeutically effective amount of (a) 5-formyl-2?-deoxyuridine (fdU or foUdR) or a 5-formyl-2?-deoxyuridine derivative, optionally in combination with 5-hydroxy-2?-deoxyuridine (hUdR); and (b) at least one composition selected from the group consisting of either 5-fluorouracil (5-FU), a 5-FU prodrug (e.g. 5-fluoro-2?-deoxyuridine (FdU)) or 5-FU metabolite. In a preferred embodiment, a subject who suffers from colorectal cancer (CRC) or metastatic colorectal cancer (mCRC) is treated with a therapeutically-effective amount of fdU and either 5-FU or the 5-FU prodrug 5-fluoro-2?-deoxyuridine (FdU). Related pharmaceutical compositions are also provided.

Abstract: A polyisocyanate composition is produced by reaction of bis(isocyanatomethyl) cyclohexane with trimethylolpropane, and contains a trimethylolpropane-monomolecular-body obtained by reaction of three molecules of bis(isocyanatomethyl) cyclohexane with one molecule of trimethylolpropane, and a trimethylolpropane-bimolecular-body obtained by reaction of five molecules of bis(isocyanatomethyl) cyclohexane with two molecules of trimethylolpropane; and the molar ratio of trimethylolpropane-monomolecular-body relative to trimethylolpropane-bimolecular-body (trimethylolpropane-monomolecular-body/trimethylolpropane-bimolecular-body) contained in the polyisocyanate composition is 1.5 or more and 4.5 or less.

Abstract: In a lathe equipped with a spindle for rotatably driving a work and a tool rest having a turret (rotary member) rotatably supporting a plurality of tools in an indexable manner about a horizontal axis, the tool rest is detachably installed on a tool rest installation portion formed so as to be positioned on an operator side so that the tools of the turret face the work side gripped by the spindle in an attachable and detachable manner.