Patents by Inventor Yoshikazu Ohya

Yoshikazu Ohya has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9477875
    Abstract: A cell monitoring device includes an outline detecting section that detects edge pixels from a cell image in a captured image of cells arranged in a single layer and generates an edge image including the detected edge pixels; a pigmented region detecting section that detects pixels of a pigmented region of the cell image in the captured image, and generates a pigmented region image including the detected pixels of the pigmented region; and an image merging section that, in a merged image obtained by overlaying the edge image and the pigmented region image together, detects a cell image region and a background image region in the captured image based on the pixel intensity variance and thus detects the cell image region in the captured image.
    Type: Grant
    Filed: November 27, 2013
    Date of Patent: October 25, 2016
    Assignee: Japan Science and Technology Agency
    Inventors: Yoshikazu Ohya, Shigeyuki Kawano, Satoru Nogami, Shinsuke Ohnuki, Shuhei Ota, Koichi Watanabe
  • Publication number: 20150302237
    Abstract: A cell monitoring device includes an outline detecting section that detects edge pixels from a cell image in a captured image of cells arranged in a single layer and generates an edge image including the detected edge pixels; a pigmented region detecting section that detects pixels of a pigmented region of the cell image in the captured image, and generates a pigmented region image including the detected pixels of the pigmented region; and an image merging section that, in a merged image obtained by overlaying the edge image and the pigmented region image together, detects a cell image region and a background image region in the captured image based on the pixel intensity variance and thus detects the cell image region in the captured image.
    Type: Application
    Filed: November 27, 2013
    Publication date: October 22, 2015
    Applicant: Japan Science and Technology Agency
    Inventors: Yoshikazu OHYA, Shigeyuki KAWANO, Satoru NOGAMI, Shinsuke OHNUKI, Shuhei OTA, Koichi WATANABE
  • Publication number: 20020107226
    Abstract: The present invention relates to rapid, reliable and effective assays for screening and identifying pharmaceutically effective compounds that specifically inhibit the biological activity of fungal GTPase proteins, particularly GTPases involved in cell wall integrity, hyphael formation, and/or other cellular functions critical to pathogenesis.
    Type: Application
    Filed: July 22, 1999
    Publication date: August 8, 2002
    Inventors: VIVIAN BERLIN, DAVID E. LEVIN, YOSHIKAZU OHYA
  • Patent number: 6271197
    Abstract: The present invention relates to rapid, reliable and effective assays for screening and identifying pharmaceutically effective compounds that specifically inhibit the biological activity of fungal GTPase proteins, particularly GTPases involved in cell wall integrity, hyphael formation, and/or other cellular functions critical to pathogenesis. Another aspect of the present invention relates to novel Candida genes and gene products.
    Type: Grant
    Filed: April 23, 1997
    Date of Patent: August 7, 2001
    Assignees: GPC-Biotech Inc., The Johns Hopkins University
    Inventors: Vivian Berlin, David E. Levin, Yoshikazu Ohya, Veronique Damagnez, Susan E. Smith
  • Patent number: 6117641
    Abstract: The present invention relates to rapid, reliable and effective assays for screening and identifying pharmaceutically effective compounds that specifically inhibit the biological activity of fungal GTPase proteins, particularly GTPases involved in cell wall integrity, hyphael formation, and/or other cellular functions critical to pathogenesis.
    Type: Grant
    Filed: April 11, 1996
    Date of Patent: September 12, 2000
    Assignees: Mitotix, Inc., The John Hopkins University
    Inventors: Vivian Berlin, David E. Levin, Yoshikazu Ohya