Patents by Inventor Yoshikazu Shimada
Yoshikazu Shimada has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20150240275Abstract: An object of the present invention is to provide enzymes associated with equol synthesis, genes coding such enzymes, and a process for producing equol and its intermediates using the enzymes and genes. The present invention provides a dihydrodaidzein synthesizing enzyme, tetrahydrodaidzein synthesizing enzyme, equol synthesizing enzyme, and genes coding these enzymes. The present invention also provides a process for synthesizing dihydrodaidzein, tetrahydrodaidzein, and/or equol using these enzymes.Type: ApplicationFiled: February 13, 2015Publication date: August 27, 2015Applicant: OTSUKA PHARMACEUTICAL CO., LTD.Inventors: Yoshikazu SHIMADA, Setsuko YASUDA, Masayuki TAKAHASHI, Takashi HAYASHI, Norihiro MIYAZAWA, Yasuhiro ABIRU, Tadaaki OHTANI, Ikutaro SATO
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Patent number: 8993296Abstract: An object of the present invention is to provide enzymes associated with equol synthesis, genes coding such enzymes, and a process for producing equol and its intermediates using the enzymes and genes. The present invention provides a dihydrodaidzein synthesizing enzyme, tetrahydrodaidzein synthesizing enzyme, equol synthesizing enzyme, and genes coding these enzymes. The present invention also provides a process for synthesizing dihydrodaidzein, tetrahydrodaidzein, and/or equol using these enzymes.Type: GrantFiled: January 15, 2014Date of Patent: March 31, 2015Assignee: Otsuka Pharmaceutical Co., Ltd.Inventors: Yoshikazu Shimada, Setsuko Yasuda, Masayuki Takahashi, Takashi Hayashi, Norihiro Miyazawa, Yasuhiro Abiru, Tadaaki Ohtani, Ikutaro Sato
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Publication number: 20140315264Abstract: An object of the present invention is to provide enzymes associated with equol synthesis, genes coding such enzymes, and a process for producing equol and its intermediates using the enzymes and genes. The present invention provides a dihydrodaidzein synthesizing enzyme, tetrahydrodaidzein synthesizing enzyme, equol synthesizing enzyme, and genes coding these enzymes. The present invention also provides a process for synthesizing dihydrodaidzein, tetrahydrodaidzein, and/or equol using these enzymes.Type: ApplicationFiled: January 15, 2014Publication date: October 23, 2014Applicant: OTSUKA PHARMACEUTICAL CO., LTD.Inventors: Yoshikazu SHIMADA, Setsuko YASUDA, Masayuki TAKAHASHI, Takashi HAYASHI, Norihiro MIYAZAWA, Yasuhiro ABIRU, Tadaaki OHTANI, Ikutaro SATO
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Patent number: 8669088Abstract: An object of the present invention is to provide enzymes associated with equol synthesis, genes coding such enzymes, and a process for producing equol and its intermediates using the enzymes and genes. The present invention provides a dihydrodaidzein synthesizing enzyme, tetrahydrodaidzein synthesizing enzyme, equol synthesizing enzyme, and genes coding these enzymes. The present invention also provides a process for synthesizing dihydrodaidzein, tetrahydrodaidzein, and/or equol using these enzymes.Type: GrantFiled: November 5, 2012Date of Patent: March 11, 2014Assignee: Otsuka Pharmaceutical Co., Ltd.Inventors: Yoshikazu Shimada, Setsuko Yasuda, Masayuki Takahashi, Takashi Hayashi, Norihiro Miyazawa, Yasuhiro Abiru, Tadaaki Ohtani, Ikutaro Sato
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Patent number: 8399232Abstract: An object of the present invention is to provide enzymes associated with equol synthesis, genes coding such enzymes, and a process for producing equol and its intermediates using the enzymes and genes. The present invention provides a dihydrodaidzein synthesizing enzyme, tetrahydrodaidzein synthesizing enzyme, equol synthesizing enzyme, and genes coding these enzymes. The present invention also provides a process for synthesizing dihydrodaidzein, tetrahydrodaidzein, and/or equol using these enzymes.Type: GrantFiled: December 25, 2008Date of Patent: March 19, 2013Assignee: Otsuka Pharmaceutical Co., Ltd.Inventors: Yoshikazu Shimada, Setsuko Yasuda, Masayuki Takahashi, Takashi Hayashi, Norihiro Miyazawa, Yasuhiro Abiru, Tadaaki Ohtani, Ikutaro Sato
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Publication number: 20100330627Abstract: An object of the present invention is to provide enzymes associated with equol synthesis, genes coding such enzymes, and a process for producing equol and its intermediates using the enzymes and genes. The present invention provides a dihydrodaidzein synthesizing enzyme, tetrahydrodaidzein synthesizing enzyme, equol synthesizing enzyme, and genes coding these enzymes. The present invention also provides a process for synthesizing dihydrodaidzein, tetrahydrodaidzein, and/or equol using these enzymes.Type: ApplicationFiled: December 25, 2008Publication date: December 30, 2010Applicant: OTSUKA PHARMACEUTICAL CO. LTD.Inventors: Yoshikazu Shimada, Setsuko Yasuda, Masayuki Takahashi, Takashi Hayashi, Norihiro Miyazawa, Yasuhiro Abiru, Tadaaki Ohtani, Ikutaro Sato
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Publication number: 20080207155Abstract: A receiver system includes an antenna to receive a high-frequency signal; a first band pass filter circuit to eliminate unnecessary frequency components from the high-frequency signal; a low-noise amplifier to amplify signal output from the first band pass filter circuit; a local oscillator to produce a local oscillation signal; a mixer to mix signal output from the low-noise amplifier and the local oscillation signal to produce an intermediate signal; a second band pass filter circuit to eliminate unnecessary frequency components from the intermediate signal; an amplifier to amplify signal output from the second band pass filter circuit; a demodulator circuit to demodulate signal output from the amplifier; an analog-to-digital converter circuit to convert signal output from the demodulator into digital signal.Type: ApplicationFiled: November 8, 2007Publication date: August 28, 2008Inventors: Yoshikazu Shimada, Hiroyuki Ashida
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Patent number: 7308241Abstract: A conventional receiver system has a filter circuit with unsatisfactory gain characteristics, and thus does not offer satisfactory reception performance. A receiver system of the invention has a filter circuit employing an equivalent inductor circuit including a capacitor, a gyrator composed of a plurality of operational transconductance amplifiers and having the capacitor as a load, and a resistor connected in series with the capacitor. A conventional receiver system has a band-pass filter circuit with a low third-order input intercept point, and thus does not offer satisfactory reception performance.Type: GrantFiled: July 19, 2006Date of Patent: December 11, 2007Assignee: Rohm Co., Ltd.Inventors: Yoshikazu Shimada, Hiroyuki Ashida
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Patent number: 7203474Abstract: A conventional receiver system has a filter circuit with unsatisfactory gain characteristics, and thus does not offer satisfactory reception performance. A receiver system of the invention has a filter circuit employing an equivalent inductor circuit including a capacitor, a gyrator composed of a plurality of operational transconductance amplifiers and having the capacitor as a load, and a resistor connected in series with the capacitor. A conventional receiver system has a band-pass filter circuit with a low third-order input intercept point, and thus does not offer satisfactory reception performance.Type: GrantFiled: October 23, 2002Date of Patent: April 10, 2007Assignee: Rohm Co., Ltd.Inventors: Yoshikazu Shimada, Hiroyuki Ashida
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Publication number: 20060258321Abstract: A conventional receiver system has a filter circuit with unsatisfactory gain characteristics, and thus does not offer satisfactory reception performance. A receiver system of the invention has a filter circuit employing an equivalent inductor circuit including a capacitor, a gyrator composed of a plurality of operational transconductance amplifiers and having the capacitor as a load, and a resistor connected in series with the capacitor. A conventional receiver system has a band-pass filter circuit with a low third-order input intercept point, and thus does not offer satisfactory reception performance.Type: ApplicationFiled: July 19, 2006Publication date: November 16, 2006Inventors: Yoshikazu Shimada, Hiroyuki Ashida
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Patent number: 6980776Abstract: The present invention provides a transceiver apparatus that permits miniaturization even when the antenna thereof is an unbalanced circuit and the transmitter circuit section and receiver circuit section thereof are balanced circuits. The transceiver apparatus is constituted comprising: a semiconductor integrated circuit device that mounts on the same semiconductor chip a balanced receiver circuit 41 for receiving a received signal as a differential input and balanced transmitter circuit 52 for outputting a transmitted signal as a differential output, and that has at least two terminals 71,72 connected to connecting nodes that connect the balanced receiver circuit 41 and the balanced transmitter circuit 52; first and second capacitors C2,C3 connected to the terminals 71, 72 respectively; an external inductor L1 connected to the first and second capacitors C2, C3; a band pass filter 2 and an antenna 1 coupled to the first capacitor C2; and a third capacitor C1 connected to the second capacitor C3.Type: GrantFiled: December 4, 2002Date of Patent: December 27, 2005Assignees: Rohm Co., Ltd, RF Chips Technology Inc.Inventors: Yoshikazu Shimada, Hiroyuki Ashida, Katsuya Ogura, Sadao Igarashi
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Publication number: 20030124987Abstract: The present invention provides a transceiver apparatus that permits miniaturization even when the antenna thereof is an unbalanced circuit and the transmitter circuit section and receiver circuit section thereof are balanced circuits.Type: ApplicationFiled: December 4, 2002Publication date: July 3, 2003Applicant: ROHM CO., LTD.Inventors: Yoshikazu Shimada, Hiroyuki Ashida, Katsuya Ogura, Sadao Igarashi
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Publication number: 20030078028Abstract: A conventional receiver system has a filter circuit with unsatisfactory gain characteristics, and thus does not offer satisfactory reception performance. A receiver system of the invention has a filter circuit employing an equivalent inductor circuit including a capacitor, a gyrator composed of a plurality of operational transconductance amplifiers and having the capacitor as a load, and a resistor connected in series with the capacitor. A conventional receiver system has a band-pass filter circuit with a low third-order input intercept point, and thus does not offer satisfactory reception performance.Type: ApplicationFiled: October 23, 2002Publication date: April 24, 2003Inventors: Yoshikazu Shimada, Hiroyuki Ashida
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Patent number: 6489669Abstract: An integrated circuit device as a first IC chip, a second IC chip, and a circuit board having a hole formed therein that is large enough to permit the second IC chip to be accommodated therein. The first and second IC chips are bonded together so as to be electrically connected together, and the first IC chip is mounted on the circuit board with the second IC chip accommodated in the hole formed in the circuit board. Here, one of the IC chips forming a chip-on-chip structure is accommodated in the hole formed in the circuit board, making further thickness reduction possible. Moreover, the obverse surfaces of the IC chips are located closer to the circuit board, making possible wireless mounting of the IC chips, despite forming a chip-on-chip structure, on the circuit board through connection using bumps. This helps reduce trouble due to inductance in a circuit that handles a high-frequency signal.Type: GrantFiled: August 27, 2001Date of Patent: December 3, 2002Assignee: Rohm Co., Ltd.Inventors: Yoshikazu Shimada, Hiroo Mochida
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Publication number: 20020151025Abstract: This invention provides the TSC403 gene having a nucleotide sequence coding for the amino acid sequence of SEQ ID NO:1, which is a novel gene of great utility particularly in the field of research, diagnosis, therapy, etc. for cancer of the lung, among other diseases.Type: ApplicationFiled: April 5, 2002Publication date: October 17, 2002Inventors: Masami Nagata, Kouichi Ozaki, Yoshikazu Shimada, Masato Horie
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Patent number: 6403785Abstract: This invention provides the TSC403 gene having a nucleotide sequence coding for the amino acid sequence of SEQ ID NO:1, which is a novel gene of great utility particularly in the field of research, diagnosis, therapy, etc. for cancer of the lung, among other diseases. In addition, this invention provides the human ING1L gene comprising a nucleotide sequence coding for the amino acid sequence of SEQ ID NO:4, which is a novel human gene useful for regulating the cell cycle, inhibiting or activating cell proliferation, studies on metabolic aging or apoptosis of cells, pathological exploration, diagnosis and therapy of cancer and other diseases, and screening for the development of new drugs.Type: GrantFiled: August 3, 2000Date of Patent: June 11, 2002Assignee: Otsuka Pharmaceutical Co., Ltd.Inventors: Masami Nagata, Kouichi Ozaki, Yoshikazu Shimada, Masato Horie
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Publication number: 20020030264Abstract: An integrated circuit device has a first IC chip, a second IC chip, and a circuit board having a hole formed therein that is large enough to permit the second IC chip to be accommodated therein. The first and second IC chips are bonded together so as to be electrically connected together, and the first IC chip is mounted on the circuit board with the second IC chip accommodated in the hole formed in the circuit board. Here, one of the IC chips forming a chip-on-chip structure is accommodated in the hole formed in the circuit board, making further thickness reduction possible. Moreover, the obverse surfaces of the IC chips are located closer to the circuit board, making possible wireless mounting of the IC chips, despite forming a chip-on-chip structure, on the circuit board through connection using bumps. This helps reduce trouble due to inductance in a circuit that handles a high-frequency signal.Type: ApplicationFiled: August 27, 2001Publication date: March 14, 2002Applicant: ROHM CO., LTD.Inventors: Yoshikazu Shimada, Hiroo Mochida
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Patent number: 5808030Abstract: An isolated hTFIIIA gene having a nucleotide sequence coding for the amino acid sequence of SEQ ID NO:1, as disclosed, and in particular the hTFIIIA gene having the nucleotide sequence of SEQ ID NO:2. The gene can be used to express a corresponding hTFIIIA protein. The gene and protein serve as transcription regulating factors, and are useful in the diagnosis or identification of hereditary disease, such as cancer or other diseases resulting from abnormal transcriptional control and, further, in analyzing the mechanisms of action thereof.Type: GrantFiled: September 5, 1995Date of Patent: September 15, 1998Assignee: Otsuka Pharmaceutical Co., Ltd.Inventors: Tsutomu Fujiwara, Satoshi Takeda, Yoshikazu Shimada, Kouichi Ozaki, Sadahito Shin, deceased
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Patent number: 5712601Abstract: An oscillation circuit is provided which is easily adjusted with a high degree of accuracy. The oscillation circuit including a filter having a time constant and an inverting amplifier which feeds back the output of the filter to the input side of the filter so that an oscillation condition is fulfilled. The filter includes a gm amplifier formed of a differential amplifier, and a capacitor. The constant current source of the differential amplifier is connected to a free running oscillation frequency adjusting circuit. The adjusting circuit includes a microcomputer, a decoder which decodes the output data of the microcomputer and a switching circuit driven by the output of the decoder and varying the current value according to the output of the decoder. A current in accordance with a current value depending on the setting of the switch flows through the constant current source.Type: GrantFiled: February 22, 1996Date of Patent: January 27, 1998Assignee: Rohm Co. Ltd.Inventors: Yoshikazu Shimada, Isoshi Takeda
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Patent number: 5604808Abstract: An FM signal phase-shifted by 90.degree. and an FM signal not phase-shifted are supplied to a multiplier to demodulate a stereo composite signal. A 90.degree. phase shifting circuit has a first oscillation circuit whose phase shift amount varies according to a timing at which the amount of a current flowing through a charging and discharging capacitor is changed. A multiplexer is provided to process the stereo composite signal to output left and right channel signals. The multiplexer has a second oscillation circuit for generating a signal multiplied by the stereo composite signal to extract the left and right channel signals from the composite signal. The first and second oscillation circuits each have a differential amplifier. The constant current of the constant current source of each differential amplifier is set by trimming-regulate it by a regulating circuit.Type: GrantFiled: November 10, 1994Date of Patent: February 18, 1997Assignee: Rohm Co., Ltd.Inventors: Isoshi Takeda, Yoshikazu Shimada