Patents by Inventor Yoshikazu Shimada

Yoshikazu Shimada has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20150240275
    Abstract: An object of the present invention is to provide enzymes associated with equol synthesis, genes coding such enzymes, and a process for producing equol and its intermediates using the enzymes and genes. The present invention provides a dihydrodaidzein synthesizing enzyme, tetrahydrodaidzein synthesizing enzyme, equol synthesizing enzyme, and genes coding these enzymes. The present invention also provides a process for synthesizing dihydrodaidzein, tetrahydrodaidzein, and/or equol using these enzymes.
    Type: Application
    Filed: February 13, 2015
    Publication date: August 27, 2015
    Applicant: OTSUKA PHARMACEUTICAL CO., LTD.
    Inventors: Yoshikazu SHIMADA, Setsuko YASUDA, Masayuki TAKAHASHI, Takashi HAYASHI, Norihiro MIYAZAWA, Yasuhiro ABIRU, Tadaaki OHTANI, Ikutaro SATO
  • Patent number: 8993296
    Abstract: An object of the present invention is to provide enzymes associated with equol synthesis, genes coding such enzymes, and a process for producing equol and its intermediates using the enzymes and genes. The present invention provides a dihydrodaidzein synthesizing enzyme, tetrahydrodaidzein synthesizing enzyme, equol synthesizing enzyme, and genes coding these enzymes. The present invention also provides a process for synthesizing dihydrodaidzein, tetrahydrodaidzein, and/or equol using these enzymes.
    Type: Grant
    Filed: January 15, 2014
    Date of Patent: March 31, 2015
    Assignee: Otsuka Pharmaceutical Co., Ltd.
    Inventors: Yoshikazu Shimada, Setsuko Yasuda, Masayuki Takahashi, Takashi Hayashi, Norihiro Miyazawa, Yasuhiro Abiru, Tadaaki Ohtani, Ikutaro Sato
  • Publication number: 20140315264
    Abstract: An object of the present invention is to provide enzymes associated with equol synthesis, genes coding such enzymes, and a process for producing equol and its intermediates using the enzymes and genes. The present invention provides a dihydrodaidzein synthesizing enzyme, tetrahydrodaidzein synthesizing enzyme, equol synthesizing enzyme, and genes coding these enzymes. The present invention also provides a process for synthesizing dihydrodaidzein, tetrahydrodaidzein, and/or equol using these enzymes.
    Type: Application
    Filed: January 15, 2014
    Publication date: October 23, 2014
    Applicant: OTSUKA PHARMACEUTICAL CO., LTD.
    Inventors: Yoshikazu SHIMADA, Setsuko YASUDA, Masayuki TAKAHASHI, Takashi HAYASHI, Norihiro MIYAZAWA, Yasuhiro ABIRU, Tadaaki OHTANI, Ikutaro SATO
  • Patent number: 8669088
    Abstract: An object of the present invention is to provide enzymes associated with equol synthesis, genes coding such enzymes, and a process for producing equol and its intermediates using the enzymes and genes. The present invention provides a dihydrodaidzein synthesizing enzyme, tetrahydrodaidzein synthesizing enzyme, equol synthesizing enzyme, and genes coding these enzymes. The present invention also provides a process for synthesizing dihydrodaidzein, tetrahydrodaidzein, and/or equol using these enzymes.
    Type: Grant
    Filed: November 5, 2012
    Date of Patent: March 11, 2014
    Assignee: Otsuka Pharmaceutical Co., Ltd.
    Inventors: Yoshikazu Shimada, Setsuko Yasuda, Masayuki Takahashi, Takashi Hayashi, Norihiro Miyazawa, Yasuhiro Abiru, Tadaaki Ohtani, Ikutaro Sato
  • Patent number: 8399232
    Abstract: An object of the present invention is to provide enzymes associated with equol synthesis, genes coding such enzymes, and a process for producing equol and its intermediates using the enzymes and genes. The present invention provides a dihydrodaidzein synthesizing enzyme, tetrahydrodaidzein synthesizing enzyme, equol synthesizing enzyme, and genes coding these enzymes. The present invention also provides a process for synthesizing dihydrodaidzein, tetrahydrodaidzein, and/or equol using these enzymes.
    Type: Grant
    Filed: December 25, 2008
    Date of Patent: March 19, 2013
    Assignee: Otsuka Pharmaceutical Co., Ltd.
    Inventors: Yoshikazu Shimada, Setsuko Yasuda, Masayuki Takahashi, Takashi Hayashi, Norihiro Miyazawa, Yasuhiro Abiru, Tadaaki Ohtani, Ikutaro Sato
  • Publication number: 20100330627
    Abstract: An object of the present invention is to provide enzymes associated with equol synthesis, genes coding such enzymes, and a process for producing equol and its intermediates using the enzymes and genes. The present invention provides a dihydrodaidzein synthesizing enzyme, tetrahydrodaidzein synthesizing enzyme, equol synthesizing enzyme, and genes coding these enzymes. The present invention also provides a process for synthesizing dihydrodaidzein, tetrahydrodaidzein, and/or equol using these enzymes.
    Type: Application
    Filed: December 25, 2008
    Publication date: December 30, 2010
    Applicant: OTSUKA PHARMACEUTICAL CO. LTD.
    Inventors: Yoshikazu Shimada, Setsuko Yasuda, Masayuki Takahashi, Takashi Hayashi, Norihiro Miyazawa, Yasuhiro Abiru, Tadaaki Ohtani, Ikutaro Sato
  • Publication number: 20080207155
    Abstract: A receiver system includes an antenna to receive a high-frequency signal; a first band pass filter circuit to eliminate unnecessary frequency components from the high-frequency signal; a low-noise amplifier to amplify signal output from the first band pass filter circuit; a local oscillator to produce a local oscillation signal; a mixer to mix signal output from the low-noise amplifier and the local oscillation signal to produce an intermediate signal; a second band pass filter circuit to eliminate unnecessary frequency components from the intermediate signal; an amplifier to amplify signal output from the second band pass filter circuit; a demodulator circuit to demodulate signal output from the amplifier; an analog-to-digital converter circuit to convert signal output from the demodulator into digital signal.
    Type: Application
    Filed: November 8, 2007
    Publication date: August 28, 2008
    Inventors: Yoshikazu Shimada, Hiroyuki Ashida
  • Patent number: 7308241
    Abstract: A conventional receiver system has a filter circuit with unsatisfactory gain characteristics, and thus does not offer satisfactory reception performance. A receiver system of the invention has a filter circuit employing an equivalent inductor circuit including a capacitor, a gyrator composed of a plurality of operational transconductance amplifiers and having the capacitor as a load, and a resistor connected in series with the capacitor. A conventional receiver system has a band-pass filter circuit with a low third-order input intercept point, and thus does not offer satisfactory reception performance.
    Type: Grant
    Filed: July 19, 2006
    Date of Patent: December 11, 2007
    Assignee: Rohm Co., Ltd.
    Inventors: Yoshikazu Shimada, Hiroyuki Ashida
  • Patent number: 7203474
    Abstract: A conventional receiver system has a filter circuit with unsatisfactory gain characteristics, and thus does not offer satisfactory reception performance. A receiver system of the invention has a filter circuit employing an equivalent inductor circuit including a capacitor, a gyrator composed of a plurality of operational transconductance amplifiers and having the capacitor as a load, and a resistor connected in series with the capacitor. A conventional receiver system has a band-pass filter circuit with a low third-order input intercept point, and thus does not offer satisfactory reception performance.
    Type: Grant
    Filed: October 23, 2002
    Date of Patent: April 10, 2007
    Assignee: Rohm Co., Ltd.
    Inventors: Yoshikazu Shimada, Hiroyuki Ashida
  • Publication number: 20060258321
    Abstract: A conventional receiver system has a filter circuit with unsatisfactory gain characteristics, and thus does not offer satisfactory reception performance. A receiver system of the invention has a filter circuit employing an equivalent inductor circuit including a capacitor, a gyrator composed of a plurality of operational transconductance amplifiers and having the capacitor as a load, and a resistor connected in series with the capacitor. A conventional receiver system has a band-pass filter circuit with a low third-order input intercept point, and thus does not offer satisfactory reception performance.
    Type: Application
    Filed: July 19, 2006
    Publication date: November 16, 2006
    Inventors: Yoshikazu Shimada, Hiroyuki Ashida
  • Patent number: 6980776
    Abstract: The present invention provides a transceiver apparatus that permits miniaturization even when the antenna thereof is an unbalanced circuit and the transmitter circuit section and receiver circuit section thereof are balanced circuits. The transceiver apparatus is constituted comprising: a semiconductor integrated circuit device that mounts on the same semiconductor chip a balanced receiver circuit 41 for receiving a received signal as a differential input and balanced transmitter circuit 52 for outputting a transmitted signal as a differential output, and that has at least two terminals 71,72 connected to connecting nodes that connect the balanced receiver circuit 41 and the balanced transmitter circuit 52; first and second capacitors C2,C3 connected to the terminals 71, 72 respectively; an external inductor L1 connected to the first and second capacitors C2, C3; a band pass filter 2 and an antenna 1 coupled to the first capacitor C2; and a third capacitor C1 connected to the second capacitor C3.
    Type: Grant
    Filed: December 4, 2002
    Date of Patent: December 27, 2005
    Assignees: Rohm Co., Ltd, RF Chips Technology Inc.
    Inventors: Yoshikazu Shimada, Hiroyuki Ashida, Katsuya Ogura, Sadao Igarashi
  • Publication number: 20030124987
    Abstract: The present invention provides a transceiver apparatus that permits miniaturization even when the antenna thereof is an unbalanced circuit and the transmitter circuit section and receiver circuit section thereof are balanced circuits.
    Type: Application
    Filed: December 4, 2002
    Publication date: July 3, 2003
    Applicant: ROHM CO., LTD.
    Inventors: Yoshikazu Shimada, Hiroyuki Ashida, Katsuya Ogura, Sadao Igarashi
  • Publication number: 20030078028
    Abstract: A conventional receiver system has a filter circuit with unsatisfactory gain characteristics, and thus does not offer satisfactory reception performance. A receiver system of the invention has a filter circuit employing an equivalent inductor circuit including a capacitor, a gyrator composed of a plurality of operational transconductance amplifiers and having the capacitor as a load, and a resistor connected in series with the capacitor. A conventional receiver system has a band-pass filter circuit with a low third-order input intercept point, and thus does not offer satisfactory reception performance.
    Type: Application
    Filed: October 23, 2002
    Publication date: April 24, 2003
    Inventors: Yoshikazu Shimada, Hiroyuki Ashida
  • Patent number: 6489669
    Abstract: An integrated circuit device as a first IC chip, a second IC chip, and a circuit board having a hole formed therein that is large enough to permit the second IC chip to be accommodated therein. The first and second IC chips are bonded together so as to be electrically connected together, and the first IC chip is mounted on the circuit board with the second IC chip accommodated in the hole formed in the circuit board. Here, one of the IC chips forming a chip-on-chip structure is accommodated in the hole formed in the circuit board, making further thickness reduction possible. Moreover, the obverse surfaces of the IC chips are located closer to the circuit board, making possible wireless mounting of the IC chips, despite forming a chip-on-chip structure, on the circuit board through connection using bumps. This helps reduce trouble due to inductance in a circuit that handles a high-frequency signal.
    Type: Grant
    Filed: August 27, 2001
    Date of Patent: December 3, 2002
    Assignee: Rohm Co., Ltd.
    Inventors: Yoshikazu Shimada, Hiroo Mochida
  • Publication number: 20020151025
    Abstract: This invention provides the TSC403 gene having a nucleotide sequence coding for the amino acid sequence of SEQ ID NO:1, which is a novel gene of great utility particularly in the field of research, diagnosis, therapy, etc. for cancer of the lung, among other diseases.
    Type: Application
    Filed: April 5, 2002
    Publication date: October 17, 2002
    Inventors: Masami Nagata, Kouichi Ozaki, Yoshikazu Shimada, Masato Horie
  • Patent number: 6403785
    Abstract: This invention provides the TSC403 gene having a nucleotide sequence coding for the amino acid sequence of SEQ ID NO:1, which is a novel gene of great utility particularly in the field of research, diagnosis, therapy, etc. for cancer of the lung, among other diseases. In addition, this invention provides the human ING1L gene comprising a nucleotide sequence coding for the amino acid sequence of SEQ ID NO:4, which is a novel human gene useful for regulating the cell cycle, inhibiting or activating cell proliferation, studies on metabolic aging or apoptosis of cells, pathological exploration, diagnosis and therapy of cancer and other diseases, and screening for the development of new drugs.
    Type: Grant
    Filed: August 3, 2000
    Date of Patent: June 11, 2002
    Assignee: Otsuka Pharmaceutical Co., Ltd.
    Inventors: Masami Nagata, Kouichi Ozaki, Yoshikazu Shimada, Masato Horie
  • Publication number: 20020030264
    Abstract: An integrated circuit device has a first IC chip, a second IC chip, and a circuit board having a hole formed therein that is large enough to permit the second IC chip to be accommodated therein. The first and second IC chips are bonded together so as to be electrically connected together, and the first IC chip is mounted on the circuit board with the second IC chip accommodated in the hole formed in the circuit board. Here, one of the IC chips forming a chip-on-chip structure is accommodated in the hole formed in the circuit board, making further thickness reduction possible. Moreover, the obverse surfaces of the IC chips are located closer to the circuit board, making possible wireless mounting of the IC chips, despite forming a chip-on-chip structure, on the circuit board through connection using bumps. This helps reduce trouble due to inductance in a circuit that handles a high-frequency signal.
    Type: Application
    Filed: August 27, 2001
    Publication date: March 14, 2002
    Applicant: ROHM CO., LTD.
    Inventors: Yoshikazu Shimada, Hiroo Mochida
  • Patent number: 5808030
    Abstract: An isolated hTFIIIA gene having a nucleotide sequence coding for the amino acid sequence of SEQ ID NO:1, as disclosed, and in particular the hTFIIIA gene having the nucleotide sequence of SEQ ID NO:2. The gene can be used to express a corresponding hTFIIIA protein. The gene and protein serve as transcription regulating factors, and are useful in the diagnosis or identification of hereditary disease, such as cancer or other diseases resulting from abnormal transcriptional control and, further, in analyzing the mechanisms of action thereof.
    Type: Grant
    Filed: September 5, 1995
    Date of Patent: September 15, 1998
    Assignee: Otsuka Pharmaceutical Co., Ltd.
    Inventors: Tsutomu Fujiwara, Satoshi Takeda, Yoshikazu Shimada, Kouichi Ozaki, Sadahito Shin, deceased
  • Patent number: 5712601
    Abstract: An oscillation circuit is provided which is easily adjusted with a high degree of accuracy. The oscillation circuit including a filter having a time constant and an inverting amplifier which feeds back the output of the filter to the input side of the filter so that an oscillation condition is fulfilled. The filter includes a gm amplifier formed of a differential amplifier, and a capacitor. The constant current source of the differential amplifier is connected to a free running oscillation frequency adjusting circuit. The adjusting circuit includes a microcomputer, a decoder which decodes the output data of the microcomputer and a switching circuit driven by the output of the decoder and varying the current value according to the output of the decoder. A current in accordance with a current value depending on the setting of the switch flows through the constant current source.
    Type: Grant
    Filed: February 22, 1996
    Date of Patent: January 27, 1998
    Assignee: Rohm Co. Ltd.
    Inventors: Yoshikazu Shimada, Isoshi Takeda
  • Patent number: 5604808
    Abstract: An FM signal phase-shifted by 90.degree. and an FM signal not phase-shifted are supplied to a multiplier to demodulate a stereo composite signal. A 90.degree. phase shifting circuit has a first oscillation circuit whose phase shift amount varies according to a timing at which the amount of a current flowing through a charging and discharging capacitor is changed. A multiplexer is provided to process the stereo composite signal to output left and right channel signals. The multiplexer has a second oscillation circuit for generating a signal multiplied by the stereo composite signal to extract the left and right channel signals from the composite signal. The first and second oscillation circuits each have a differential amplifier. The constant current of the constant current source of each differential amplifier is set by trimming-regulate it by a regulating circuit.
    Type: Grant
    Filed: November 10, 1994
    Date of Patent: February 18, 1997
    Assignee: Rohm Co., Ltd.
    Inventors: Isoshi Takeda, Yoshikazu Shimada