Abstract: The present invention provides a composition and a method both for treating or preventing atopic dermatitis effectively. Provided is a composition which contains an acetylcholine inhibitor, e.g., an anticholinergic substance, as an active ingredient. Also provided is a method which includes a step of administering an acetylcholine inhibitor such as an anticholinergic substance. The detailed mechanism of the development of atopic dermatitis has not been elucidated so far. Therefore, it has been difficult to treat atopic dermatitis effectively. The composition according to the present invention can treat atopic dermatitis effectively through the inhibition of the action of acetylcholine.

Abstract: A detection device is a detection device for estimating the occurrence of an allergic reaction, and includes a detection section which noninvasively acquires information of an internal skin or a skin surface as detection data for estimating the allergic reaction. The detection section includes a skin temperature detection section which detects a skin temperature, and at least one detection section which acquires the detection data other than the skin temperature.

Abstract: Provision of a stable ?-lipoic acid. A method for producing ?-lipoic acid nanoparticles, the method comprising the steps of: preparing an aqueous dispersion liquid containing ?-lipoic acid and a nonionic surfactant; adding a divalent metal salt into the aqueous dispersion liquid, wherein the divalent metal salt is a divalent metal halide, a divalent metal acetate or a divalent metal gluconate; and adding an alkali metal carbonate or an alkali metal phosphate into the aqueous dispersion liquid which has been added with the divalent metal salt, thereby forming ?-lipoic acid nanoparticles.

Abstract: Provision of a stable ?-lipoic acid. A method for producing ?-lipoic acid nanoparticles, the method comprising the steps of: preparing an aqueous dispersion liquid containing ?-lipoic acid and a nonionic surfactant; adding a divalent metal salt into the aqueous dispersion liquid, wherein the divalent metal salt is a divalent metal halide, a divalent metal acetate or a divalent metal gluconate; and adding an alkali metal carbonate or an alkali metal phosphate into the aqueous dispersion liquid which has been added with the divalent metal salt, thereby forming ?-lipoic acid nanoparticles.

Abstract: It is an object to provide a thermoplastic elastomer material for a paper feeding roller having all of a high coefficient of friction, great delivery force, a polishing workability and an abrasion resistance which are characteristics to be required for the paper feeding roller. It is preferable that 20 to 80 parts by weight of an olefin-based thermoplastic elastomer and 80 to 20 parts by weight of a styrene-based thermoplastic elastomer are contained and a total amount of both thermoplastic elastomers is 100 parts by weight.

Abstract: It is an object to provide a thermoplastic elastomer material for a paper feeding roller having all of a high coefficient of friction, great delivery force, a polishing workability and an abrasion resistance which are characteristics to be required for the paper feeding roller. It is preferable that 20 to 80 parts by weight of an olefin based thermoplastic elastomer and 80 to 20 parts by weight of a styrene based thermoplastic elastomer are contained and a total amount of both thermoplastic elastomers is 100 parts by weight.

Abstract: A primary side of a transformer has a switching transistor to on-off control the current flowing in a primary winding on a primary side. A secondary side of the transformer has a commutating side FET to be turned on by applying the induced voltage of a tertiary winding on a secondary side of a current transformer, and a flywheel side FET with the primary winding on the primary side of the current transformer connected thereto in series. The current transformation ratio of the current transformer is small in the initial period when the flywheel side FET is turned on, and then, the current transformation ratio is increased by current controlling means comprising a saturable reactor, a diode or the like.

Abstract: A primary side of a transformer has a switching transistor to on-off control the current flowing in a primary winding on a primary side. A secondary side of the transformer has a commutating side FET to be turned on by applying the induced voltage of a tertiary winding on a secondary side of a current transformer, and a flywheel side FET with the primary winding on the primary side of the current transformer connected thereto in series. The current transformation ratio of the current transformer is small in the initial period when the flywheel side FET is turned on, and then, the current transformation ratio is increased by current controlling means comprising a saturable reactor, a diode or the like.