Patents by Inventor Yoshiki Murakami
Yoshiki Murakami has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230405039Abstract: Provided are an miR-29a-like nucleic acid reagent and a pharmaceutical composition that aim to inhibit liver fibrosis. An miR-29a-like nucleic acid reagent according to the present invention includes nucleic acid having a base sequence of Sequence ID No. 1 that includes DNA and RNA and in which at least one nucleotide residue is a modified residue: Sequence ID No. 1: uagcaccaggctgucc. A liver fibrosis inhibitor and a pharmaceutical composition according to the present invention include the miR-29a-like nucleic acid reagent according to the present invention, and are preferably used for oral administration.Type: ApplicationFiled: November 10, 2021Publication date: December 21, 2023Inventors: Yoshiki MURAKAMI, Masahiko KURODA
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Patent number: 11014520Abstract: An airbag apparatus includes a longitudinal webbing guide configured to guide movement in a longitudinal direction of webbing, an inflatable airbag disposed along an outer side of the webbing guide, a bag cover configured to cover the airbag, and an upper side coupling member configured to couple a guide upper end of the webbing guide to a cover upper end of the bag cover, and move upward along the webbing together with the airbag when the airbag is inflated and deployed. A seatbelt apparatus includes the airbag apparatus.Type: GrantFiled: May 21, 2018Date of Patent: May 25, 2021Assignee: Joyson Safety Systems Japan K.K.Inventors: Yoshiki Murakami, Hiroaki Isozaki
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Publication number: 20200377049Abstract: An airbag apparatus includes a longitudinal webbing guide configured to guide movement in a longitudinal direction of webbing, an inflatable airbag disposed along an outer side of the webbing guide, a bag cover configured to cover the airbag, and an upper side coupling member configured to couple a guide upper end of the webbing guide to a cover upper end of the bag cover, and move upward along the webbing together with the airbag when the airbag is inflated and deployed. A seatbelt apparatus includes the airbag apparatus.Type: ApplicationFiled: May 21, 2018Publication date: December 3, 2020Inventors: Yoshiki MURAKAMI, Hiroaki ISOZAKI
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Patent number: 10183646Abstract: According to one embodiment, an occupant restraining apparatus includes a webbing W, a tongue 4, an airbag 20 provided along the webbing W, a bag cover 40 surrounding the airbag 20, and a webbing guide 30 through which the webbing W is passed. The webbing guide 30 extends continuously from one end to the other end of the bag cover 40. The lower end of the bag cover 40 surrounds the lower end of the webbing guide 30, and the lower end of the bag cover 40 and the lower end of the webbing guide 30 are bound together. The upper end of the bag cover 40 surrounds the upper end of the webbing guide 30, and the upper end of the bag cover 40 and the upper end of the webbing guide 30 are bound together.Type: GrantFiled: May 3, 2017Date of Patent: January 22, 2019Assignee: JOYSON SAFETY SYSTEMS JAPAN K.K.Inventors: Yoshiki Murakami, Hiroaki Isozaki, Tatsuya Higuchi, Yongliang Huang
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Publication number: 20180281726Abstract: A seat belt apparatus includes webbing, a tubular webbing guide through which the webbing is movably inserted in an insertion direction, an inflatable airbag disposed along an outer side of the webbing guide, and a bag cover configured to cover the airbag, wherein the bag cover includes a first cover end in the insertion direction and a second cover end on an opposite side of the first cover end in the insertion direction, and the webbing guide includes a first guide end alongside the first cover end, a second guide end alongside the second cover end, and a peripheral wall continuously extending between the first guide end and the second guide end so as to form a space between the peripheral wall and the webbing.Type: ApplicationFiled: March 23, 2018Publication date: October 4, 2018Inventors: Yoshiki MURAKAMI, Hiroaki ISOZAKI
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Patent number: 9963098Abstract: A vehicle occupant restraint device includes an airbag that is provided in a shoulder belt position of a seat belt while being folded in a belt-like shape to be capable of inflating upon receiving a predetermined actuating signal, and the seat belt is wound by a single winding device. The airbag is folded to surround a slide guide including a hard member having seat-belt passing portions arranged at predetermined intervals in an insertion direction of webbing and a soft member supporting the hard member. The airbag smoothly slides along the webbing through the slide guide when the seat belt is pulled out.Type: GrantFiled: March 23, 2015Date of Patent: May 8, 2018Assignee: TAKATA CORPORATIONInventors: Hiroaki Isozaki, Yoshiki Murakami, Hikaru Kameyoshi
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Publication number: 20170327075Abstract: According to one embodiment, an occupant restraining apparatus includes a webbing W, a tongue 4, an airbag 20 provided along the webbing W, a bag cover 40 surrounding the airbag 20, and a webbing guide 30 through which the webbing W is passed. The webbing guide 30 extends continuously from one end to the other end of the bag cover 40. The lower end of the bag cover 40 surrounds the lower end of the webbing guide 30, and the lower end of the bag cover 40 and the lower end of the webbing guide 30 are bound together. The upper end of the bag cover 40 surrounds the upper end of the webbing guide 30, and the upper end of the bag cover 40 and the upper end of the webbing guide 30 are bound together.Type: ApplicationFiled: May 3, 2017Publication date: November 16, 2017Applicant: TAKATA CORPORATIONInventors: Yoshiki MURAKAMI, Hiroaki ISOZAKI, Tatsuya HIGUCHI, Yongliang HUANG
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Publication number: 20170106828Abstract: A vehicle occupant restraint device includes an airbag that is provided in a shoulder belt position of a seat belt while being folded in a belt-like shape to be capable of inflating upon receiving a predetermined actuating signal, and the seat belt is wound by a single winding device. The airbag is folded to surround a slide guide including a hard member having seat-belt passing portions arranged at predetermined intervals in an insertion direction of webbing and a soft member supporting the hard member.Type: ApplicationFiled: March 23, 2015Publication date: April 20, 2017Applicant: TAKATA CORPORATIONInventors: Hiroaki ISOZAKI, Yoshiki MURAKAMI, Hikaru KAMEYOSHI
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Patent number: 9479461Abstract: In a computer on the transmission side, an NW driver, which is recognized, by the OS, as an NIC driver, stores data to be transmitted and a destination SPA into a memory, and outputs a transaction layer packet (TLP), which has been generated by a first computer, to a PCIe switch. A first NIC logic of the PCIe switch of the PCIe switch corresponding to the first computer on the transmission side adds a system port address (SPA) to the TLP transferred from the first computer, and transfers the data of the TLP to a port associated with a second NIC logic and having an address indicated by the SPA (destination SPA). The second NIC logic having received the data writes the receive data into a memory of a second computer, on the reception side, which is connected to another PCIe switch where the second NIC logic exists.Type: GrantFiled: March 16, 2012Date of Patent: October 25, 2016Assignee: Hitachi, Ltd.Inventors: Shuhei Eguchi, Ryo Yamagata, Yoshiki Murakami
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Patent number: 9333939Abstract: Provided are an airbag, an airbag unit, and a vent hole open/close control method that facilitate control of opening and closing of a vent hole, and suppress an increase in weight and cost of the airbag unit vent hole. The airbag 1 includes a vent hole 4, an open/close device 5 configured to open and close the vent hole 4, and a stretch tether 6 stretchable in stages and connected to the open/close device 5 and an airbag component. The stretch tether 6 assumes, depending on an expansion and unfolding status of the airbag 1, a first stage including transition from a slack state to a tense state, a second stage including stretching to a predetermined length while maintaining the tense state, and a third stage including being slackened when the driver contacts the airbag 1. The open/close device 5 maintains the vent hole 4 in the open state in the first stage, maintains the vent hole 4 in the closed state in the second stage, and shifts the vent hole 4 to the open state in the third stage.Type: GrantFiled: March 21, 2013Date of Patent: May 10, 2016Assignee: TAKATA CORPORATIONInventors: Kimihiro Koshikawa, Yoshiki Murakami
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Patent number: 9027963Abstract: A tension member for an airbag, and an airbag device are provided in each of which the tensile force is controlled continuously with a simple configuration. An airbag device includes an airbag that is normally folded and is inflated and deployed in a case of an emergency, an inflator for supplying gas into the airbag, a retainer for retaining the airbag and the inflator, and a tension member that controls a shape or a function of the airbag by using tension. The tension member for an airbag includes two end portions connected to respective portions of the airbag that are movable relative to each other when the airbag is inflated and deployed, a widened portion provided between the two end portions, and a breaking section provided in the widened portion in such a manner as to extend in a direction of widening of the widened portion and configured to break depending on a magnitude of tension applied between the two end portions.Type: GrantFiled: July 27, 2012Date of Patent: May 12, 2015Assignee: Takata CorporationInventors: Yoshiki Murakami, Kimihiro Koshikawa
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Publication number: 20150042082Abstract: Provided are an airbag, an airbag unit, and a vent hole open/close control method that facilitate control of opening and closing of a vent hole, and suppress an increase in weight and cost of the airbag unit vent hole. The airbag 1 includes a vent hole 4, an open/close device 5 configured to open and close the vent hole 4, and a stretch tether 6 stretchable in stages and connected to the open/close device 5 and an airbag component. The stretch tether 6 assumes, depending on an expansion and unfolding status of the airbag 1, a first stage including transition from a slack state to a tense state, a second stage including stretching to a predetermined length while maintaining the tense state, and a third stage including being slackened when the driver contacts the airbag 1. The open/close device 5 maintains the vent hole 4 in the open state in the first stage, maintains the vent hole 4 in the closed state in the second stage, and shifts the vent hole 4 to the open state in the third stage.Type: ApplicationFiled: March 21, 2013Publication date: February 12, 2015Applicant: Takata CorporationInventors: Kimihiro Koshikawa, Yoshiki Murakami
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Publication number: 20150031574Abstract: A method for classifying test body fluid samples into either of two groups selected from four groups consisting of chronic hepatitis C, chronic hepatitis B, non-alcoholic steatohepatitis (NASH) and normal liver, is provided. In one or plural embodiment(s), it relates to a method for classifying test body fluid samples into either of two groups selected from four groups consisting of chronic hepatitis C, chronic hepatitis B, non-alcoholic steatohepatitis (NASH) and normal liver. The method includes a measurement of an expression level of the one or plural non-coding RNA(s) in the test body fluid sample.Type: ApplicationFiled: February 22, 2013Publication date: January 29, 2015Applicant: SUMITOMO BAKELITE CO., LTD.Inventors: Yoshiki Murakami, Takahiro Ochiya
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Publication number: 20140269754Abstract: In a computer on the transmission side, an NW driver, which is recognized, by the OS, as an NIC driver, stores data to be transmitted and a destination SPA into a memory, and outputs a transaction layer packet (TLP), which has been generated by a first computer, to a PCIe switch. A first NIC logic of the PCIe switch of the PCIe switch corresponding to the first computer on the transmission side adds a system port address (SPA) to the TLP transferred from the first computer, and transfers the data of the TLP to a port associated with a second NIC logic and having an address indicated by the SPA (destination SPA). The second NIC logic having received the data writes the receive data into a memory of a second computer, on the reception side, which is connected to another PCIe switch where the second NIC logic exists.Type: ApplicationFiled: March 16, 2012Publication date: September 18, 2014Applicant: Hitachi, Ltd.Inventors: Shuhei Eguchi, Ryo Yamagata, Yoshiki Murakami
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Publication number: 20140191497Abstract: A tension member for an airbag, and an airbag device are provided in each of which the tensile force is controlled continuously with a simple configuration. An airbag device includes an airbag that is normally folded and is inflated and deployed in a case of an emergency, an inflator for supplying gas into the airbag, a retainer for retaining the airbag and the inflator, and a tension member that controls a shape or a function of the airbag by using tension. The tension member for an airbag includes two end portions connected to respective portions of the airbag that are movable relative to each other when the airbag is inflated and deployed, a widened portion provided between the two end portions, and a breaking section provided in the widened portion in such a manner as to extend in a direction of widening of the widened portion and configured to break depending on a magnitude of tension applied between the two end portions.Type: ApplicationFiled: July 27, 2012Publication date: July 10, 2014Inventors: Yoshiki Murakami, Kimihiro Koshikawa
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Publication number: 20140112131Abstract: Provided are a PCIe switch provided with a bandwidth control function, and a computer system using the same. The PCIe switch has: input ports to which are connected initiators that generate packets; output ports to which are connected targets that are the transmission destinations of the packets; and an output port adjustment section intervening between the input ports and the output ports, for adjusting the output of packets from the input ports to the output ports. The input ports further have a bandwidth control section that establishes bandwidth limit values beforehand for each of a plurality of divided groups; classifies packets transmitted from the initiators into any of the plurality of groups according to a predetermined rule; and outputs the classified packets to the output adjustment section, on the basis of the bandwidth limit values.Type: ApplicationFiled: June 17, 2011Publication date: April 24, 2014Applicant: Hitachi, Ltd.Inventors: Takashi Todaka, Yoshiki Murakami, Junji Yamamoto
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Patent number: 8706311Abstract: An electric power planning apparatus is provided. The apparatus has an initial plan creating section, a generation amount probability density distribution creating section, an economic load dispatch calculating section, and a display section. The initial plan creating section creates an initial plan based on a demand predicted value, a predicted value of a natural energy electric power source power generation output amount, and electric power source equipment data. The generation amount probability density distribution creating section creates a probability density distribution using fluctuation bands of the demand and of the natural energy electric power source power generation output amount. The economic load dispatch calculating section calculates an output allocation based on the initial plan and the probability density distribution to create a prediction distribution of a power generation output of the controllable electric power source. The display section displays the prediction distribution.Type: GrantFiled: July 22, 2011Date of Patent: April 22, 2014Assignee: Kabushiki Kaisha ToshibaInventors: Yoko Kosaka, Takenori Kobayashi, Yoshiki Murakami, Hideo Kusano
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Publication number: 20130013233Abstract: An electric-power-generation level predicting apparatus 1 includes a memory unit 20 that stores, as past data relating to a past electric power generation level of an electric power generator, past data containing information at multiple time points in each day, and an predicted-value calculating unit 13 that calculates, as time-series data containing an occurrence probability, an predicted value of the past data relating to an electric power generation level of the electric power generator based on a statistical correlation between different times in the past data or a statistical correlation between locations of the different electric power generators. The predicted-value calculating unit 13 includes a variance-covariance-matrix generator unit 131 that generates a variance-covariance matrix based on the past data, and a random-number generator unit 132 that generates a random number following the probability distribution based on the variance-covariance matrix.Type: ApplicationFiled: March 18, 2011Publication date: January 10, 2013Inventors: Yoshiki Murakami, Takenori Kobayashi, Katsutoshi Hiromasa, Yoko Kosaka, Hideo Kusano, Kenji Watanabe, Hideki Hayashi
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Publication number: 20120238459Abstract: A method for predicting therapeutic effect of combination therapy with peginterferon and ribavirin in chronic hepatitis C therapy, comprising: a drug-sensitivity marker detection step of detecting a drug-sensitivity marker in a biological sample; and a drug-sensitivity evaluation step of evaluating drug sensitivity of the biological sample on the basis of an expression level of the drug-sensitivity marker, wherein the biological sample is a cell or tissue derived from liver, and the drug-sensitivity marker comprises at least one microRNA selected from the group consisting of microRNAs shown in SEQ ID NOs: 1 to 37.Type: ApplicationFiled: September 7, 2010Publication date: September 20, 2012Inventor: Yoshiki Murakami
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Publication number: 20120109393Abstract: An electric power planning apparatus is provided. The apparatus has an initial plan creating section, a generation amount probability density distribution creating section, an economic load dispatch calculating section, and a display section. The initial plan creating section creates an initial plan based on a demand predicted value, a predicted value of a natural energy electric power source power generation output amount, and electric power source equipment data. The generation amount probability density distribution creating section creates a probability density distribution using fluctuation bands of the demand and of the natural energy electric power source power generation output amount. The economic load dispatch calculating section calculates an output allocation based on the initial plan and the probability density distribution to create a prediction distribution of a power generation output of the controllable electric power source. The display section displays the prediction distribution.Type: ApplicationFiled: July 22, 2011Publication date: May 3, 2012Inventors: Yoko Kosaka, Takenori Kobayashi, Yoshiki Murakami, Hideo Kusano