Abstract: An antitumor agent comprising a compound selected from the group consisting of Compounds A to D described in the specification, or a salt thereof, for treating a malignant tumor patient expressing EGFR having exon 20 insertion mutation.

Abstract: An antitumor agent comprising a compound selected from the group consisting of Compounds A to D described in the specification, or a salt thereof, for treating a malignant tumor patient expressing EGFR having exon 20 insertion mutation.

Abstract: An antitumor agent comprising a compound selected from the group consisting of Compounds A to D described in the specification, or a salt thereof, for treating a malignant tumor patient expressing EGFR having exon 20 insertion mutation.

Abstract: This invention relates to an immunomodulator comprising, as an active ingredient, (S)—N-(4-amino-5-(quinolin-3-yl)-6,7,8,9-tetrahydropyrimido[5,4-b]indolizin-8-yl)acrylamide represented by Formula (I) or a salt thereof and a pharmaceutical composition for the prevention or treatment of a disease that can be ameliorated via immunomodulation.

Abstract: A receiver is provided with a connector including: an outer earbud contact composed of a tube-shaped conductor and provided on the earbud side, an inner earbud contact arranged inside the outer earbud contact via an earbud-side insulator, an outer cable contact composed of a tube-shaped conductor and provided on the cable side, and an inner cable contact arranged inside the outer cable contact via a cable-side insulator; a coaxial connector being formed when the outer contacts are screwed into each other.

Abstract: Solution Means: Earphone 10 possesses an outer ear canal insertion member for which at least a portion can be inserted into the outer ear canal, housing 11 onto which the outer ear canal insertion member can be installed and removed, and driver unit 41 which is disposed within housing 11 and which generates sound, and driver unit 41 is maintained within the interior space of the support member by the rigid support member being installed within housing 11.

Abstract: A receiver is provided with a connector including: an outer earbud contact composed of a tube-shaped conductor and provided on the earbud side, an inner earbud contact arranged inside the outer earbud contact via an earbud-side insulator, an outer cable contact composed of a tube-shaped conductor and provided on the cable side, and an inner cable contact arranged inside the outer cable contact via a cable-side insulator; a coaxial connector being formed when the outer contacts are screwed into each other.

Abstract: An earphone that possesses an outer ear canal insertion member for which at least a portion can be inserted into the outer ear canal, a housing onto which the outer ear canal insertion member is installed, a driver unit which is disposed within the housing and which generates sound, a first retention member through the interior of which passes a cable connected at one end to the driver unit and which is itself directly installed to the housing, and a second retention member through the interior of which passes the cable and which is itself installed to the first retention member; and when the second retention member is installed to the first retention member, the first retention member grasps the cable.

Abstract: An earphone that possesses an outer ear canal insertion member for which at least a portion can be inserted into the outer ear canal, a housing onto which the outer ear canal insertion member is installed, a driver unit which is disposed within the housing and which generates sound, a first retention member through the interior of which passes a cable connected at one end to the driver unit and which is itself directly installed to the housing, and a second retention member through the interior of which passes the cable and which is itself installed to the first retention member; and when the second retention member is installed to the first retention member, the first retention member grasps the cable.

Abstract: An earphone is disclosed. The earphone comprises an external auditory meatus insertion member, a casing and a driver unit. The external auditory meatus insertion member has a part which is insertable into an external auditory meatus. The external auditory meatus insertion member is detachable from the casing. The driver unit is disposed within the casing to generate sounds. The the external auditory meatus insertion member further includes an elastically deformable soft insertion member and a highly rigid hard insertion member.

Abstract: Solution Means: Earphone 10 possesses an outer ear canal insertion member for which at least a portion can be inserted into the outer ear canal, housing 11 onto which the outer ear canal insertion member can be installed and removed, and driver unit 41 which is disposed within housing 11 and which generates sound, and driver unit 41 is maintained within the interior space of the support member by the rigid support member being installed within housing 11.