Patents by Inventor Yoshinori Akimoto

Yoshinori Akimoto has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of stabilizing protein C or activated protein C and the stabilized composition obtained by said method
    Patent number: 5962299
    Abstract: A method for stabilizing protein C or activated protein C and a preparation obtained by said method are provided, said method and preparation being applicable during procedures such as isolation and purification, lyophilization, heating, etc. or when stored.To a salt buffer containing protein C or activated protein C and sodium ion are added at least one amino acids, and further either one or a combination of albumin and a non-ionic surfactant.
    Type: Grant
    Filed: April 29, 1996
    Date of Patent: October 5, 1999
    Assignees: Juridical Foundation The Chemo-Sero-Therapeutic Research Institute, Teijin Limited
    Inventors: Kazumasa Miyata, Yoshinori Akimoto, Yoichi Ogata, Tomohiro Nakagaki
  • Purification of gammaglobulin derivative
    Patent number: 4302384
    Abstract: Process for the production of a highly purified S-sulfonated gammaglobulin by treating an S-sulfonated gammaglobulin obtained by sulfonating a conventional gammaglobulin with an ion exchanger in a buffer solution for development, and thereby absorbing single molecular S-sulfonated gammaglobulin thereto, and eluting the single molecular S-sulfonated gammaglobulin with a buffer solution for elution. This process can give the desired S-sulfonated gammaglobulin having a high content of single molecule and an extremely small anticomplementary activity (e.g. CH.sub.50 of 10% or less) and also an excellent shaking stability from the conventional gammaglobulin in an industrial scale.
    Type: Grant
    Filed: November 30, 1979
    Date of Patent: November 24, 1981
    Assignee: Juridical Foundation, The Chemo-Sero-Therapeutic Research Institute
    Inventors: Akinobu Funatsu, Shuzoh Oyama, Yoshinori Akimoto, Komei Ohashi