Patents by Inventor Yoshinori Takema
Yoshinori Takema has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 7041658Abstract: Disclosed herein are a method of inhibiting hair growth, which comprises administering an inhibitor of elastase-like enzymes or a neutral endopeptidase inhibitor, and use of an inhibitor of elastase-like enzymes or a neutral endopeptidase inhibitor for the preparation of a hair-growth inhibitor.Type: GrantFiled: March 16, 2004Date of Patent: May 9, 2006Assignee: Kao CorporationInventors: Naoko Tsuji, Shigeru Moriwaki, Atsushi Ohuchi, Yoshinori Takema, Yasuto Suzuki, Genji Imokawa
-
Publication number: 20060093567Abstract: Disclosed herein are a method of inhibiting hair growth, which comprises administering an inhibitor of elastase-like enzymes or a neutral endopeptidase inhibitor, and-use of an inhibitor of elastase-like enzymes or a neutral endopeptidase inhibitor for the preparation of a hair-growth inhibitor.Type: ApplicationFiled: December 20, 2005Publication date: May 4, 2006Applicant: KAO CORPORATIONInventors: Naoko Tsuji, Shigeru Moriwaki, Atsushi Ohuchi, Yoshinori Takema, Yasuto Suzuki, Genji Imokawa
-
Publication number: 20040175349Abstract: Disclosed herein are a method of inhibiting hair growth, which comprises administering an inhibitor of elastase-like enzymes or a neutral endopeptidase inhibitor, and use of an inhibitor of elastase-like enzymes or a neutral endopeptidase inhibitor for the preparation of a hair-growth inhibitor.Type: ApplicationFiled: March 16, 2004Publication date: September 9, 2004Applicant: KAO CORPORATIONInventors: Naoko Tsuji, Shigeru Moriwaki, Atsushi Ohuchi, Yoshinori Takema, Yasuto Suzuki, Genji Imokawa
-
Patent number: 6747017Abstract: Disclosed herein are a method of inhibiting hair growth, which comprises administering an inhibitor of elastase-like enzymes or a neutral endopeptidase inhibitor, and use of an inhibitor of elastase-like enzymes or a neutral endopeptidase inhibitor for the preparation of a hair-growth inhibitor.Type: GrantFiled: December 28, 1998Date of Patent: June 8, 2004Assignee: Kao CorporationInventors: Naoko Tsuji, Shigeru Moriwaki, Atsushi Ohuchi, Yoshinori Takema, Yasuto Suzuki, Genji Imokawa
-
Patent number: 6436920Abstract: The invention relates to wrinkling modifiers and anti-aging cosmetic compositions which each comprise a guanidine derivative represented by the following general formula (1): wherein is a heterocyclic group selected from azetidine, pyrrolidine, piperidine, piperazine or morpholine, and R1 and R2 are the same or different from each other and independently a hydrogen atom, or an alkyl, hydroxyl, hydroxyalkyl, carboxyl, carboxyalkyl or amidino group, or a salt thereof. The cosmetic compositions are excellent in the effects of suppressing wrinkling and of removing wrinkles and give users a pleasant feeling upon use.Type: GrantFiled: August 23, 2001Date of Patent: August 20, 2002Assignee: Kao CorporationInventors: Tsutomu Fujimura, Noriko Ito, Minoru Nagai, Toshiya Ono, Akira Yamamuro, Yoshinori Takema
-
Publication number: 20020037880Abstract: Disclosed herein are a method of inhibiting hair growth, which comprises administering an inhibitor of elastase-like enzymes or a neutral endopeptidase inhibitor, and use of an inhibitor of elastase-like enzymes or a neutral endopeptidase inhibitor for the preparation of a hair-growth inhibitor.Type: ApplicationFiled: December 28, 1998Publication date: March 28, 2002Inventors: NAOKO TSUJI, SHIGERU MORIWAKI, ATSUSHI OHUCHI, YOSHINORI TAKEMA, YASUTO SUZUKI, GENJI IMOKAWA
-
Publication number: 20020022611Abstract: The invention relates to wrinkling modifiers and anti-aging cosmetic compositions which each comprise a guanidine derivative represented by the following general formula (1): 1Type: ApplicationFiled: August 23, 2001Publication date: February 21, 2002Applicant: KAO CORPORATIONInventors: Tsutomu Fujimura, Noriko Ito, Minoru Nagai, Toshiya Ono, Akira Yamamuro, Yoshinori Takema
-
Patent number: 6306848Abstract: The invention relates to wrinkling modifiers and anti-aging cosmetic compositions which each comprise a guanidine derivative represented by the following general formula (1): wherein is a heterocyclic group selected from azetidine, pyrrolidine, piperidine, piperazine or morpholine, and R1 and R2 are the same or different from each other and independently a hydrogen atom, or an alkyl, hydroxyl, hydroxyalkyl, carboxyl, carboxyalkyl or amidino group, or a salt thereof. The cosmetic compositions are excellent in the effects of suppressing wrinkling and of removing wrinkles and give users a pleasant feeling upon use.Type: GrantFiled: April 6, 1999Date of Patent: October 23, 2001Assignee: Kao CorporationInventors: Tsutomu Fujimura, Noriko Ito, Minoru Nagai, Toshiya Ono, Akira Yamamuro, Yoshinori Takema
-
Patent number: 6171595Abstract: The present invention provides a skin external preparation comprising a compound of the formula (1), (2), (3) or (4). wherein X represents COOH, etc., Z represents CONH2, etc. and R1 and R7 individually represent a hydrogen atom, etc. The above-described compound has excellent effects, for example, for preventing or alleviating skin aging or inhibiting hair growth.Type: GrantFiled: January 11, 2000Date of Patent: January 9, 2001Assignee: Kao CorporationInventors: Yasuto Suzuki, Naoko Tsuji, Shigeru Moriwaki, Yoshinori Nishizawa, Yoshinori Takema, Satoshi Kanazawa, Genji Imokawa, Yukihiro Ohashi, Mikako Watanabe
-
Patent number: 6075052Abstract: The present invention provides a skin external preparation comprising a compound of the formula (1), (2), (3) or (4). ##STR1## wherein X represents COOH, etc., Z represents CONH.sub.2, etc. and R.sup.1 and R.sup.7 individually represent a hydrogen atom, etc.The above-described compound has excellent effects, for example, for preventing or alleviating skin aging or inhibiting hair growth.Type: GrantFiled: March 25, 1999Date of Patent: June 13, 2000Assignee: Kao CorporationInventors: Yasuto Suzuki, Naoko Tsuji, Shigeru Moriwaki, Yoshinori Nishizawa, Yoshinori Takema, Satoshi Kanazawa, Genji Imokawa, Yukihiro Ohashi, Mikako Watanabe
-
Patent number: 5939078Abstract: A wrinkle-care product, an aging-preventive cosmetic and a skin cosmetic each comprising a guanidine derivative of formula (I) or an acid addition salt thereof: ##STR1## wherein R1 represents a hydrogen atom, a lower alkyl group or --(AO).sub.m --(BO).sub.n --D--E ?wherein A and B may be the same or different and each represents an alkylene group having 2 to 8 carbon atoms; D represents a binding hand, --CO--, or an unsubstituted or substituted alkylene group having 1 to 6 carbon atoms; E represents a hydrogen atom, a lower alkyl group, an aralkyl group or an unsubstituted or substituted aryl group; m is a number of from 1 to 6; and n is a number of from 0 to 6!; k is a number of from 1 to 10; and G represents a hydrogen atom, a hydroxyl group, a carboxyl group, a sulfonate group or a phosphate group. These products are excellent in the effects of inhibiting wrinkling and smoothing wrinkles without damaging the physiological conditions of the skin.Type: GrantFiled: November 18, 1996Date of Patent: August 17, 1999Assignee: Kao CorporationInventors: Tsutomu Fujimura, Ayumi Ogawa, Kazue Tsukahara, Yoshinori Takema, Minoru Nagai, Toshiya Ono
-
Patent number: 5723497Abstract: The present invention relates to an amine derivative represented by the following general formula (I) or (II): ##STR1## wherein R.sup.1 means a heteroatom-containing C.sub.1 -C.sub.40 hydrocarbon group which may have a ring structure, or the like; R.sup.2 -R.sup.5 each denote a C.sub.1 -C.sub.20 hydrocarbon group, hydrogen or the like; A.sup.1 represents ##STR2## or R.sup.15 --Z--.sup.16 --(CH.sub.2).sub.n --; B.sup.1 stands for hydrogen, a C.sub.1 -C.sub.10 hydrocarbon group, nitrogen or the like; C.sup.1 denotes hydrogen, a C.sub.1 -C.sub.10 hydrocarbon group, nitrogen, alcohol residue, phosphoric acid residue or the like; a dermatologic preparation containing the same; and a process for producing the amine derivative. This amine derivative has excellent effects of smoothing or removing wrinkles and improving keratinization.Type: GrantFiled: September 18, 1995Date of Patent: March 3, 1998Assignee: Kao CorporationInventors: Yukihiro Ohashi, Yukihiro Yada, Yoshinori Takema, Taketoshi Fujimori, Akira Kawamata, Hiroyuki Ohsu, Kazuhiko Higuchi, Genji Imokawa, Hiroshi Kusuoku, Ayumi Ogawa, Tsutomu Fujimura
-
Patent number: 5709816Abstract: Singlet oxygen quenchers containing as an active component a compound represented by the following formula or (2): ##STR1## wherein each of R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.10 and n are as described herein, and external compositions containing these compounds are provided for the prevention and treatment of various forms of damage to living bodies caused by singlet oxygen, and are thus quite useful as antiinflammation agents, anti-aging agents, agents preventing darkening of the skin, agents preventing protein denaturation, inhibitors against formation of sunburn cells, agents preventing lipid peroxidation, agents preventing DNA damage, and particularly in the fields of medicines and cosmetics as external compositions for the skin.Type: GrantFiled: July 22, 1996Date of Patent: January 20, 1998Assignee: Kao CorporationInventors: Masakazu Yamaguchi, Hiroyuki Ohsu, Eiichi Nishizawa, Mitsuru Sugiyama, Koichi Nakamura, Yoshinori Takema
-
Patent number: 5681864Abstract: A composition for external skin care comprising an amine derivative represented by the following formula (1), ##STR1## wherein R.sup.1 is a linear, branched, or cyclic saturated or unsaturated hydrocarbon group having 4-40 carbon atoms, and R.sup.2, R.sup.3, R.sup.4, R.sup.5, and R.sup.6 are individually a hydrogen atom or a hydrocarbon group having 1-10 carbon atoms, which may be substituted or unsubstituted by 1 or more hydroxy groups; or an acid addition salt thereof, in an amount from 0.0001 to less than 0.1% by weight; and a method of curing wrinkles and keratinization of the skin characterized by applying said amine derivative or its salt to the skin.Type: GrantFiled: December 6, 1996Date of Patent: October 28, 1997Assignee: Kao CorporationInventors: Yukihiro Ohashi, Taketoshi Fujimori, Minoru Nagai, Akira Kawamata, Yukihiro Yada, Kazuhiko Higuchi, Genji Imokawa, Yoshinori Takema, Yukiko Sakaino, Ayumi Ogawa, Tsutomu Fujimura
-
Patent number: 5552445Abstract: A composition for external skin care comprising an amine derivative represented by the following formula (1), ##STR1## wherein R.sup.1 is a linear, branched, or cyclic saturated or unsaturated hydrocarbon group having 4-40 carbon atoms, and R.sup.2, R.sup.3, R.sup.4, R.sup.5 and R.sup.6 are individually a hydrogen atom or a hydrocarbon group having 1-10 carbon atoms, which may be substituted or unsubstituted by 1 or more hydroxy groups; or an acid addition salt thereof, in an amount from 0.0001 to less than 0.1% by weight; and a method of curing wrinkles and keratinization of the skin characterized by applying said amine derivative or its salt to the skin.Type: GrantFiled: March 23, 1994Date of Patent: September 3, 1996Assignee: Kao CorporationInventors: Yukihiro Ohashi, Taketoshi Fujimori, Minoru Nagai, Akira Kawamata, Yukihiro Yada, Kazuhiko Higuchi, Genji Imokawa, Yoshinori Takema, Yukiko Sakaino, Ayumi Ogawa, Tsutomu Fujimura
-
Patent number: 5032311Abstract: A novel acidic heteropolysaccharide which comprises as its structural units arabinose, mannose, galactose, glucuronic acid, and xylose, at a specific ratio. The polysaccharide can be prepared by culturing a callus induced from a plant belonging to the genus Polianthes L. in a culture medium containing plant hormones. The polysaccharide can be used as a component of agents for external application and detergents, and provides good moisturizing effects and a smooth, satisfying feeling upon use. When formulated in detergents, they produce remarkable improvement in a clean, rich feeling upon use.Type: GrantFiled: February 27, 1990Date of Patent: July 16, 1991Assignee: KAO CorporationInventors: Kazuya Otsuji, Yasuki Honda, Kikuhiko Okamoto, Hakaru Inaoka, Satoshi Takano, Yukio Sugimura, Noriko Okamura, Kazumi Saito, Yoshinori Takema, Toshiyuki Suzuki
-
Patent number: 4923809Abstract: A novel acidic heteropolysaccharide which comprises as its structural units arabinose, mannose, galactose, glucuronic acid, and xylose, at a specific ratio. The polysaccharide can be prepared by culturing a callus induced from a plant belonging to the genus Polianthes L. in a culture medium containing plant hormones. The polysaccharide can be used as a component of agents for external application and detergents, and provides good moisturizing effects and a smooth, satisfying feeling upon use. When formulated in detergents, they produce remarkable improvement in a clean, rich feeling upon use.Type: GrantFiled: March 9, 1988Date of Patent: May 8, 1990Assignee: KAO CorporationInventors: Kazuya Otsuji, Yasuki Honda, Kikuhiko Okamoto, Hakaru Inaoka, Satoshi Takano, Yukio Sugimura, Noriko Okamura, Kazumi Saito, Yoshinori Takema, Toshiyuki Suzuki
-
Patent number: 4743441Abstract: A film-forming cosmetic composition useful as a facial pack, nail enamel, eye liner etc., which comprises a copolymer of vinyl alcohol and alkyl vinyl ether, being referred to simply as PVA/AVE, consisting of 98 to 80 mole % of vinyl alcohol monomer units and 2 to 20 mole % of linear or branched alkyl vinyl monomer units having from 1 to 6 carbon atoms. The molar ratio of the vinyl alcohol monomer units to the alkyl vinyl ether monomer units is in the range of from 95/5 to 85/15. The PVA/AVE according to the invention has no acetic groups with ester bonds in a molecule. Instead, there are alkyl or alkenyl groups having ether bonds which serve for steric hindrance for preventing gelation of an aqueous solution of such copolymer. From this reason, the PVA/AVE does not undergo any hydrolysis as time passes and is thus excellent in storage stability.Type: GrantFiled: September 15, 1986Date of Patent: May 10, 1988Assignee: Kao CorporationInventors: Yoshinori Takema, Rikio Tsushima, Yutaka Yasuda, Yoshinao Kono