Patents by Inventor Yoshio Hayashi

Yoshio Hayashi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240010045
    Abstract: In an air conditioner, a heat medium circuit includes: a first branch part, a first merging part, a second branch part, and a second merging part. A first flow rate adjusting unit is disposed in the heat medium circuit between the first branch part and an outside-air heat exchanger or between the outside-air heat exchanger and the first merging part, and a second flow rate adjusting unit is disposed in the heat medium circuit between the first branch part and the first heater core or between the first heater core and the first merging part. At least one of the first flow rate adjusting unit or the second flow rate adjusting unit is configured to optionally adjust the flow rate of the heat medium, and a controller controls the at least one of the first flow rate adjusting unit or the second flow rate adjusting unit.
    Type: Application
    Filed: September 13, 2023
    Publication date: January 11, 2024
    Inventors: Naito MUTO, Yoshiki KATOH, Hiroaki KAWANO, Yukihisa IJUIN, Yoshinori ICHISHI, Yoshio HAYASHI, Junki HIRAYAMA, Yasuhiro YOKOO
  • Patent number: 11566047
    Abstract: Provided is a peptide having a short chain length, for example, having the number of amino acid residues of 20 or less and having a high myostatin inhibitory activity. The present invention is a peptide comprising an amino acid sequence represented by Formula (1) in the specification and having the number of amino acid residues of 20 or less.
    Type: Grant
    Filed: August 8, 2017
    Date of Patent: January 31, 2023
    Assignee: TOKYO UNIVERSITY OF PHARMACY & LIFE SCIENCES
    Inventors: Yoshio Hayashi, Kentaro Takayama, Yoichi Negishi
  • Publication number: 20220226479
    Abstract: There is provided technology for promoting permeation of a substance into a cell layer. Provided is a cell layer permeation promoter comprising a compound represented by general formula (1). Also provided is a composition for facilitating drug absorption that contains the cell layer permeation promoter, said composition being for facilitating absorption of a drug into a living body. Also provided is a pharmaceutical composition that contains the cell layer permeation promoter and furthermore contains a drug to be absorbed into a living body.
    Type: Application
    Filed: March 19, 2020
    Publication date: July 21, 2022
    Applicants: University of Tsukuba, Tokyo University of Pharmacy and Life Sciences
    Inventors: Takeo USUI, Yoko NAGUMO, Minagi MUKAIYAMA, Yoshio HAYASHI, Atsuhiko TANIGUCHI, Chihiro UCHIYAMA
  • Patent number: 11140893
    Abstract: The present invention provides a method of stopping larvae of sessile invertebrates in the settlement stage from swimming or crawling in water, by irradiating light comprising the spectrum of 409 to 412 nm and a part of 400 to 440 nm, to the larvae in the settlement stage.
    Type: Grant
    Filed: March 24, 2014
    Date of Patent: October 12, 2021
    Assignee: THE CHUGOKU ELECTRIC POWER CO., INC.
    Inventors: Toshiharu Yanagawa, Shinsuke Saito, Keiji Yamashita, Kyoko Kamiya, Yoshio Hayashi
  • Patent number: 11134670
    Abstract: The present invention provides a method of suppressing larvae of barnacles in the settlement stage from settling on a substrate in water by irradiating light comprising the spectrum of 409 to 412 nm and a part of 400 to 460 nm to larvae of barnacles in the settlement stage in a direction from the substrate to the larvae of barnacles in the settlement stage.
    Type: Grant
    Filed: December 8, 2014
    Date of Patent: October 5, 2021
    Assignees: THE CHUGOKU ELECTRIC POWER CO., INC., SESSILE RESEARCH CORPORATION
    Inventors: Toshiharu Yanagawa, Shinsuke Saito, Keiji Yamashita, Kyoko Kamiya, Yoshio Hayashi
  • Patent number: 11134669
    Abstract: The present invention provides a method of killing larvae of sessile invertebrates in the settlement stage in water, comprising the step of irradiating light comprising the spectrum of 409 to 412 nm, to the larvae in the settlement stage.
    Type: Grant
    Filed: March 24, 2014
    Date of Patent: October 5, 2021
    Assignees: THE CHUGOKU ELECTRIC POWER CO., INC., SESSILE RESEARCH CORPORATION
    Inventors: Toshiharu Yanagawa, Shinsuke Saito, Keiji Yamashita, Kyoko Kamiya, Yoshio Hayashi
  • Patent number: 11134671
    Abstract: The present invention is a method of preventing settlement of a sessile organism on a structure in water, including irradiating light comprising the spectrum of 409 to 412 nm to the structure where settlement of the sessile organism is prevented.
    Type: Grant
    Filed: March 27, 2015
    Date of Patent: October 5, 2021
    Assignees: THE CHUGOKU ELECTRIC POWER CO., INC., SESSILE RESEARCH CORPORATION
    Inventors: Toshiharu Yanagawa, Shinsuke Saito, Keiji Yamashita, Kyoko Kamiya, Yoshio Hayashi
  • Patent number: 10829512
    Abstract: The present invention provides a means capable of selectively introducing a disulfide bond with respect to two free thiol groups located in a molecule of an organic compound such as a peptide, or the like, in a short time by a simple treatment and also by a chemically stable method. A nitrogen-containing compound represented by Chemical Formula 1 below or a salt thereof: The symbols shown in Chemical Formula 1 are the same as defined in the specification.
    Type: Grant
    Filed: May 22, 2017
    Date of Patent: November 10, 2020
    Assignees: Tokyo University of Pharmacy & Life Sciences, Kokusan Chemical Co., Ltd.
    Inventors: Yoshio Hayashi, Akihiro Taguchi, Kentaro Fukumoto
  • Patent number: 10590320
    Abstract: To provide novel adhesive molecules. An adhesive molecule having an amino acid sequence of SEQ ID NO. 1, or an amino acid sequence including a conservative substitution, a deletion, an insertion and/or a modification in the sequence of SEQ ID NO. 1.
    Type: Grant
    Filed: March 23, 2015
    Date of Patent: March 17, 2020
    Assignees: THE CHUGOKU ELECTRIC POWER CO., INC., SESSILE RESEARCH CORPORATION
    Inventors: Tsukasa Yoshizaki, Keiji Yamashita, Kyoko Kamiya, Kohichi Suzuki, Yoshio Hayashi
  • Patent number: 10550153
    Abstract: To provide a peptide that selectively activates type 2 neuromedin U receptor and is chemically stable under physiological conditions. A peptide represented by Formula (1) described in the specification.
    Type: Grant
    Filed: January 19, 2018
    Date of Patent: February 4, 2020
    Assignees: TOKYO UNIVERSITY OF PHARMACY & LIFE SCIENCES, NATIONAL CEREBRAL AND CARDIOVASCULAR CENTER, KYOTO PHARMACEUTICAL UNIVERSITY
    Inventors: Yoshio Hayashi, Kentaro Takayama, Mikiya Miyazato, Kenji Kangawa, Kenji Mori, Akira Yamamoto, Toshiyasu Sakane
  • Publication number: 20190359652
    Abstract: To provide a peptide that selectively activates type 2 neuromedin U receptor and is chemically stable under physiological conditions. A peptide represented by Formula (1) described in the specification.
    Type: Application
    Filed: January 19, 2018
    Publication date: November 28, 2019
    Inventors: Yoshio HAYASHI, Kentaro TAKAYAMA, Mikiya MIYAZATO, Kenji KANGAWA, Kenji MORI, Akira YAMAMOTO, Toshiyasu SAKANE
  • Publication number: 20190177370
    Abstract: Provided is a peptide having a short chain length, for example, having the number of amino acid residues of 20 or less and having a high myostatin inhibitory activity. The present invention is a peptide comprising an amino acid sequence represented by Formula (1) in the specification and having the number of amino acid residues of 20 or less.
    Type: Application
    Filed: August 8, 2017
    Publication date: June 13, 2019
    Inventors: Yoshio HAYASHI, Kentaro TAKAYAMA, Yoichi NEGISHI
  • Publication number: 20190169228
    Abstract: The present invention provides a means capable of selectively introducing a disulfide bond with respect to two free thiol groups located in a molecule of an organic compound such as a peptide, or the like, in a short time by a simple treatment and also by a chemically stable method. A nitrogen-containing compound represented by Chemical Formula 1 below or a salt thereof: The symbols shown in Chemical Formula 1 are the same as defined in the specification.
    Type: Application
    Filed: May 22, 2017
    Publication date: June 6, 2019
    Inventors: Yoshio Hayashi, Akihiro Taguchi, Kentaro Fukumoto
  • Publication number: 20180362817
    Abstract: To provide novel adhesive molecules. An adhesive molecule having an amino acid sequence of SEQ ID NO. 1, or an amino acid sequence including a conservative substitution, a deletion, an insertion and/or a modification in the sequence of SEQ ID NO. 1.
    Type: Application
    Filed: March 23, 2015
    Publication date: December 20, 2018
    Inventors: Tsukasa YOSHIZAKI, Keiji YAMASHITA, Kyoko KAMIYA, Kohichi SUZUKI, Yoshio HAYASHI
  • Publication number: 20180079940
    Abstract: To provide novel adhesive molecules. An adhesive molecule having an amino acid sequence of SEQ ID NO. 1, or an amino acid sequence including a conservative substitution, a deletion, an insertion and/or a modification in the sequence of SEQ ID NO. 1.
    Type: Application
    Filed: March 23, 2015
    Publication date: March 22, 2018
    Inventors: Tsukasa YOSHIZAKI, Keiji YAMASHITA, Kyoko KAMIYA, Kohichi SUZUKI, Yoshio HAYASHI
  • Publication number: 20180009013
    Abstract: The present invention is a method of suppressing bio-film formation on a structure in water, including irradiating light comprising the spectrum of 409 to 412 nm to the structure where bio-film formation is to be suppressed.
    Type: Application
    Filed: March 27, 2015
    Publication date: January 11, 2018
    Inventors: Toshiharu YANAGAWA, Shinsuke SAITO, Keiji YAMASHITA, Kyoko KAMIYA, Yoshio HAYASHI
  • Publication number: 20170290326
    Abstract: The present invention provides a method of suppressing larvae of barnacles in the settlement stage from settling on a substrate in water by irradiating light comprising the spectrum of 409 to 412 nm and a part of 400 to 460 nm to larvae of barnacles in the settlement stage in a direction from the substrate to the larvae of barnacles in the settlement stage.
    Type: Application
    Filed: December 8, 2014
    Publication date: October 12, 2017
    Inventors: Toshiharu YANAGAWA, Shinsuke SAITO, Keiji YAMASHITA, Kyoko KAMIYA, Yoshio HAYASHI
  • Publication number: 20170290327
    Abstract: The present invention is a method of preventing settlement of a sessile organism on a structure in water, including irradiating light comprising the spectrum of 409 to 412 nm to the structure where settlement of the sessile organism is prevented.
    Type: Application
    Filed: March 27, 2015
    Publication date: October 12, 2017
    Inventors: Toshiharu YANAGAWA, Shinsuke SAITO, Keiji YAMASHITA, Kyoko KAMIYA, Yoshio HAYASHI
  • Publication number: 20170172135
    Abstract: The present invention provides a method of killing larvae of sessile invertebrates in the settlement stage in water, comprising the step of irradiating light comprising the spectrum of 409 to 412 nm, to the larvae in the settlement stage.
    Type: Application
    Filed: March 24, 2014
    Publication date: June 22, 2017
    Inventors: Toshiharu YANAGAWA, Shinsuke SAITO, Keiji YAMASHITA, Kyoko KAMIYA, Yoshio HAYASHI
  • Publication number: 20170164602
    Abstract: The present invention provides a method of stopping larvae of sessile invertebrates in the settlement stage from swimming or crawling in water, by irradiating light comprising the spectrum of 409 to 412 nm and a part of 400 to 440 nm, to the larvae in the settlement stage.
    Type: Application
    Filed: March 24, 2014
    Publication date: June 15, 2017
    Applicants: THE CHUGOKU ELECTRIC POWER CO., INC., SESSILE RESEARCH CORPORATION
    Inventors: Toshiharu YANAGAWA, Shinsuke SAITO, Keiji YAMASHITA, Kyoko KAMIYA, Yoshio HAYASHI