Patents by Inventor Yoshiyuki Tokieda

Yoshiyuki Tokieda has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Recombinant anti-osteopontin antibody and use thereof
    Patent number: 7241873
    Abstract: A recombinant antibody in which at least the constant regions in the heavy chain and the light chain have been converted into human-origin regions and which inhibits the binding of an integrin recognizing the RGD sequence to osteopontin or its fragment and inhibits the binding of an integrin recognizing the SVVYGLR sequence or a sequence corresponding thereto to osteopontin or its fragment. This antibody is useful as a remedy for autoimmune diseases and a remedy for rheumatism or rheumatoid arthritis. Thus, a method of treating autoimmune diseases, rheumatism or rheumatoid arthritis is provided. This osteopontin antibody is useful in a diagnostic for rheumatism and a method of diagnosing rheumatism too.
    Type: Grant
    Filed: September 25, 2002
    Date of Patent: July 10, 2007
    Assignees: Juridical Foundation the Chemo-sero-therapeutic Research Institute, Astellas Pharma Inc.
    Inventors: Toshimitsu Uede, Shigeyuki Kon, Nobuchika Yamamoto, Hirofumi Higuchi, Masaharu Torikai, Yoshiyuki Tokieda, Toshihiro Nakashima, Hiroaki Maeda
  • Recombinant anti-osteopontin antibody and use thereof
    Publication number: 20060002923
    Abstract: A recombinant antibody in which at least the constant regions in the heavy chain and the light chain have been converted into human-origin regions and which inhibits the binding of an integrin recognizing the RGD sequence to osteopontin or its fragment and inhibits the binding of an integrin recognizing the SVVYGLR sequence or a sequence corresponding thereto to osteopontin or its fragment. This antibody is useful as a remedy for autoimmune diseases and a remedy for rheumatism or rheumatoid arthritis. Thus, a method of treating autoimmune diseases, rheumatism or rheumatoid arthritis is provided. This osteopontin antibody is useful in a diagnostic for rheumatism and a method of diagnosing rheumatism too.
    Type: Application
    Filed: September 25, 2002
    Publication date: January 5, 2006
    Applicants: IMMUNO-BIOLOGICAL LABORATORIES CO., LTD., FUJISAWA PHARMACEUTICAL CO., LTD.
    Inventors: Toshimitsu Uede, Shigeyuki Kon, Nobuchika Yamamoto, Hirofumi Higuchi, Masaharu Torikai, Yoshiyuki Tokieda, Toshihiro Nakashima, Hiroaki Maeda